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The map label for this gene is rsmB [H]

Identifier: 124027398

GI number: 124027398

Start: 493180

End: 494598

Strand: Direct

Name: rsmB [H]

Synonym: Hbut_0511

Alternate gene names: 124027398

Gene position: 493180-494598 (Clockwise)

Preceding gene: 124027397

Following gene: 124027399

Centisome position: 29.58

GC content: 48.84

Gene sequence:

>1419_bases
ATGGCTGCCAGCGCAGAGGAACTCGCAAAGATGGTGTGGGAACACATAGAAGCTGAGCGCAGCAATAAGCCTAAGCTCTC
AGTGCCAGCTAAGGGGCTCAGAATACTTGTTGAAGCTGTTAAGCTCGCAGAGGAGTTTAAACCTAGTCAGCACGCCAAAA
GAGTAGTATTTCACAAGCATGGTGTGCTTGGAACGGGCTTAGATAGGCTTCTAACATCAATATTCTATGATACGATGAAA
CGTATGGGTCTGCTTGACCGTGTCGCAGCAGAACTAGCCAACGTGCCTACGGTACTCATACTTGATCCTTGGCTGCGTGC
AGCTCTCCGTTTAGCAGTAGACATAGTGTTATTCCACCGGCCCGACAAGAACACGTTGCACAGGCTACGCTGGATTGTGG
CAGACTTTATCTCAGCCAAGACACATCCTTACGTAGGAATGTTCTACTGGCAGACATTCGACAAACTCCTCGAATATCGC
CCAAAGCCTAAAACTGTCGAAGAGGCACTTGAATGGAAATACCTACTACCAGCCTGGCTCATCCGGAGGATGCGCAGCCT
CCTAGGCGAGGAGGAGTCCGAGAAATTATTCGAAGCGCTCAACAAGAGGCCGCTGATAAGCATCCGCGTAAACACGCTGA
AGACCACTGTTGAGGAGGTCGTAGAGGAATTAAAGAGAGAAGGTAAAAACCCAATCGTCAGCACGAGGGTGCCGGTTATA
GTAAAGTTTGAGGGTCCATACGACTTTGACCGGAGCCGACTCTATCGTGAAGGCAAGTTTGTTATACAAGAGGAGGCTAG
TGCCGCAGCATCGATTATACTTGATCCAAAGCCTGGCATGACCGTGGTGGATTTAGCTGCAGCACCGGGTGGCAAGACGA
GCCATATAGCTGAGCTAATGAAGAACCATGGTAGAATATATGCATTCGACATTGACCGGGTCAGAATAAAACGTATGAGG
ATGATCCTGCGCAGAATGGGAATAACCATAGTACGCATCTTTGAGAAAGATGCAAGGGAGGCGCCAAGAATTCTAGGAGA
AGAGATAGCCGACCGGGTACTTCTTGATGCCCCATGTACAAGCACTGGTACTATAGCGAAGAATCCCGAGCTTAGATGGA
GAGTTAGGGAGGAGGGTCTCGAAGAGATAGTTAAGCTGCAAAGGGAGATGTTGGAAGCAGCAGCGAAGCTAGTAAAGCCC
GGCGGAAGACTACTCTATACAACATGCAGTCTTCTACCCGAGGAGAACGAGGATAACATAAAGTGGTTCCTCAAGAGACA
CTCTGAGTTCAAACTAGTACCGCTCAATGGGCCATATGATCCTTCGCCACTTCTCCATGGCACTATGAGGGCTTGGCCAC
ATCGTCACGATACAATAGGATTCTTCTATGCATTGTTAGAGAAGAAGGAGAGGAGATGA

Upstream 100 bases:

>100_bases
CCATTGTCAGCTTCTACAACTCGTTGTAGCCAGCAGATACCCACATAATAGGGGGTGCATCTACTAGCCATCTAACCTAT
ACGTTAGGGGGCTAAGGGAA

Downstream 100 bases:

>100_bases
TATTCAGCCGAGGCCCCGTTTACTCCTCACGATCCTATAGGGCCTCGGCCAACTCGGCACTCATCACCCAAACCGATTAT
TATCCCATACCTGGGTTTAA

Product: tRNA and rRNA cytosine-C5-methylase

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MAASAEELAKMVWEHIEAERSNKPKLSVPAKGLRILVEAVKLAEEFKPSQHAKRVVFHKHGVLGTGLDRLLTSIFYDTMK
RMGLLDRVAAELANVPTVLILDPWLRAALRLAVDIVLFHRPDKNTLHRLRWIVADFISAKTHPYVGMFYWQTFDKLLEYR
PKPKTVEEALEWKYLLPAWLIRRMRSLLGEEESEKLFEALNKRPLISIRVNTLKTTVEEVVEELKREGKNPIVSTRVPVI
VKFEGPYDFDRSRLYREGKFVIQEEASAAASIILDPKPGMTVVDLAAAPGGKTSHIAELMKNHGRIYAFDIDRVRIKRMR
MILRRMGITIVRIFEKDAREAPRILGEEIADRVLLDAPCTSTGTIAKNPELRWRVREEGLEEIVKLQREMLEAAAKLVKP
GGRLLYTTCSLLPEENEDNIKWFLKRHSEFKLVPLNGPYDPSPLLHGTMRAWPHRHDTIGFFYALLEKKERR

Sequences:

>Translated_472_residues
MAASAEELAKMVWEHIEAERSNKPKLSVPAKGLRILVEAVKLAEEFKPSQHAKRVVFHKHGVLGTGLDRLLTSIFYDTMK
RMGLLDRVAAELANVPTVLILDPWLRAALRLAVDIVLFHRPDKNTLHRLRWIVADFISAKTHPYVGMFYWQTFDKLLEYR
PKPKTVEEALEWKYLLPAWLIRRMRSLLGEEESEKLFEALNKRPLISIRVNTLKTTVEEVVEELKREGKNPIVSTRVPVI
VKFEGPYDFDRSRLYREGKFVIQEEASAAASIILDPKPGMTVVDLAAAPGGKTSHIAELMKNHGRIYAFDIDRVRIKRMR
MILRRMGITIVRIFEKDAREAPRILGEEIADRVLLDAPCTSTGTIAKNPELRWRVREEGLEEIVKLQREMLEAAAKLVKP
GGRLLYTTCSLLPEENEDNIKWFLKRHSEFKLVPLNGPYDPSPLLHGTMRAWPHRHDTIGFFYALLEKKERR
>Mature_471_residues
AASAEELAKMVWEHIEAERSNKPKLSVPAKGLRILVEAVKLAEEFKPSQHAKRVVFHKHGVLGTGLDRLLTSIFYDTMKR
MGLLDRVAAELANVPTVLILDPWLRAALRLAVDIVLFHRPDKNTLHRLRWIVADFISAKTHPYVGMFYWQTFDKLLEYRP
KPKTVEEALEWKYLLPAWLIRRMRSLLGEEESEKLFEALNKRPLISIRVNTLKTTVEEVVEELKREGKNPIVSTRVPVIV
KFEGPYDFDRSRLYREGKFVIQEEASAAASIILDPKPGMTVVDLAAAPGGKTSHIAELMKNHGRIYAFDIDRVRIKRMRM
ILRRMGITIVRIFEKDAREAPRILGEEIADRVLLDAPCTSTGTIAKNPELRWRVREEGLEEIVKLQREMLEAAAKLVKPG
GRLLYTTCSLLPEENEDNIKWFLKRHSEFKLVPLNGPYDPSPLLHGTMRAWPHRHDTIGFFYALLEKKERR

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=280, Percent_Identity=33.9285714285714, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI76150623, Length=280, Percent_Identity=33.9285714285714, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI270288816, Length=347, Percent_Identity=31.700288184438, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI23199998, Length=347, Percent_Identity=31.700288184438, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI8922322, Length=299, Percent_Identity=32.7759197324415, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI270288818, Length=299, Percent_Identity=32.7759197324415, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI32698918, Length=185, Percent_Identity=35.6756756756757, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI39995082, Length=276, Percent_Identity=25.7246376811594, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI301336155, Length=276, Percent_Identity=25.7246376811594, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI11545785, Length=196, Percent_Identity=28.0612244897959, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI40316918, Length=261, Percent_Identity=30.2681992337165, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI2367212, Length=301, Percent_Identity=33.5548172757475, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI87081985, Length=314, Percent_Identity=30.8917197452229, Blast_Score=129, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17536757, Length=320, Percent_Identity=32.5, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI115534021, Length=227, Percent_Identity=30.3964757709251, Blast_Score=95, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI71998419, Length=301, Percent_Identity=27.906976744186, Blast_Score=95, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI25143471, Length=275, Percent_Identity=28, Blast_Score=88, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324268, Length=310, Percent_Identity=33.2258064516129, Blast_Score=154, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6319447, Length=270, Percent_Identity=29.2592592592593, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI22024126, Length=284, Percent_Identity=35.5633802816901, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24668781, Length=234, Percent_Identity=33.7606837606838, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21356513, Length=234, Percent_Identity=33.7606837606838, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21356579, Length=236, Percent_Identity=30.0847457627119, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21355201, Length=207, Percent_Identity=29.4685990338164, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19920494, Length=187, Percent_Identity=28.3422459893048, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 54397; Mature: 54266

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASAEELAKMVWEHIEAERSNKPKLSVPAKGLRILVEAVKLAEEFKPSQHAKRVVFHKH
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
GVLGTGLDRLLTSIFYDTMKRMGLLDRVAAELANVPTVLILDPWLRAALRLAVDIVLFHR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHEEEC
PDKNTLHRLRWIVADFISAKTHPYVGMFYWQTFDKLLEYRPKPKTVEEALEWKYLLPAWL
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
IRRMRSLLGEEESEKLFEALNKRPLISIRVNTLKTTVEEVVEELKREGKNPIVSTRVPVI
HHHHHHHHCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCEEECCCCEE
VKFEGPYDFDRSRLYREGKFVIQEEASAAASIILDPKPGMTVVDLAAAPGGKTSHIAELM
EEECCCCCCCHHHHHHCCCEEEEECCCCCEEEEECCCCCCEEEEEECCCCCCHHHHHHHH
KNHGRIYAFDIDRVRIKRMRMILRRMGITIVRIFEKDAREAPRILGEEIADRVLLDAPCT
HCCCCEEEEECHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
STGTIAKNPELRWRVREEGLEEIVKLQREMLEAAAKLVKPGGRLLYTTCSLLPEENEDNI
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCHH
KWFLKRHSEFKLVPLNGPYDPSPLLHGTMRAWPHRHDTIGFFYALLEKKERR
HHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AASAEELAKMVWEHIEAERSNKPKLSVPAKGLRILVEAVKLAEEFKPSQHAKRVVFHKH
CCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
GVLGTGLDRLLTSIFYDTMKRMGLLDRVAAELANVPTVLILDPWLRAALRLAVDIVLFHR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHEEEC
PDKNTLHRLRWIVADFISAKTHPYVGMFYWQTFDKLLEYRPKPKTVEEALEWKYLLPAWL
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
IRRMRSLLGEEESEKLFEALNKRPLISIRVNTLKTTVEEVVEELKREGKNPIVSTRVPVI
HHHHHHHHCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCEEECCCCEE
VKFEGPYDFDRSRLYREGKFVIQEEASAAASIILDPKPGMTVVDLAAAPGGKTSHIAELM
EEECCCCCCCHHHHHHCCCEEEEECCCCCEEEEECCCCCCEEEEEECCCCCCHHHHHHHH
KNHGRIYAFDIDRVRIKRMRMILRRMGITIVRIFEKDAREAPRILGEEIADRVLLDAPCT
HCCCCEEEEECHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
STGTIAKNPELRWRVREEGLEEIVKLQREMLEAAAKLVKPGGRLLYTTCSLLPEENEDNI
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCHH
KWFLKRHSEFKLVPLNGPYDPSPLLHGTMRAWPHRHDTIGFFYALLEKKERR
HHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]