Click here to switch to the map view.

The map label for this gene is tgtA [H]

Identifier: 124027360

GI number: 124027360

Start: 451790

End: 452269

Strand: Reverse

Name: tgtA [H]

Synonym: Hbut_0471

Alternate gene names: 124027360

Gene position: 452269-451790 (Counterclockwise)

Preceding gene: 124027361

Following gene: 124027359

Centisome position: 27.13

GC content: 50.21

Gene sequence:

>480_bases
TTGATCATTAGGCGTGCACGGCCCGAAGAGGTTGTTAGGCTTAGAGCAATCGCAGACTATCAGTTTGGCTTTCCTGCAGG
CGACCTATTAATCCCGGATAATGTGGTTGTAGGTGTTTCCCCTGCAACGCGCCGTATAAGGGAGATTTACGGCGAGGAGG
GGCTGCTGGCTGTCCTCCGTGCACATGATTACTTGTACTCTCTCTCGCTATTAGGCGCCAAGAGGTTGCTAGCTCTTCCC
GAGCCTCGTCTCCGCGCAAGGCTTCGTGTTGAAACACCTCCCTCCAAGAGCATTAATTGTAGAATTATAGAAACTATTGA
TCATGATCTCCGGCCCGGCGATGAGGTTATCGTGTTAAACTCTAGTGGCGAGCTTGTAGGTGTCGGCAGACTAAGATTAT
CGCCGACGGAAATACTTGAGAACGAGTGTTGGGGTGAGGCTATTAGGCTTAGGAAAACTGTTAAGGGGGATAATTCCTAG

Upstream 100 bases:

>100_bases
GTGTTGTGAAAAAGTAGTATTGCTTGCTCGGTCATAGTAGGCGTGCCGTTATTTACATAGAGTCGCCTCTTTTTCACCTG
CATCGGGGGCTGTTAGGGCC

Downstream 100 bases:

>100_bases
CTGAGCTTAGGGTTATGCGGGCTTGGCGTTTAGGGCTAGGTTTGAGTATAAGGGGATAAGGATAGCTTACGATGAGGCAC
TCTTAGAGGGAGCAAGTCTA

Product: putative RNA modification enzyme

Products: NA

Alternate protein names: Archaeal tRNA-guanine transglycosylase [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MIIRRARPEEVVRLRAIADYQFGFPAGDLLIPDNVVVGVSPATRRIREIYGEEGLLAVLRAHDYLYSLSLLGAKRLLALP
EPRLRARLRVETPPSKSINCRIIETIDHDLRPGDEVIVLNSSGELVGVGRLRLSPTEILENECWGEAIRLRKTVKGDNS

Sequences:

>Translated_159_residues
MIIRRARPEEVVRLRAIADYQFGFPAGDLLIPDNVVVGVSPATRRIREIYGEEGLLAVLRAHDYLYSLSLLGAKRLLALP
EPRLRARLRVETPPSKSINCRIIETIDHDLRPGDEVIVLNSSGELVGVGRLRLSPTEILENECWGEAIRLRKTVKGDNS
>Mature_159_residues
MIIRRARPEEVVRLRAIADYQFGFPAGDLLIPDNVVVGVSPATRRIREIYGEEGLLAVLRAHDYLYSLSLLGAKRLLALP
EPRLRARLRVETPPSKSINCRIIETIDHDLRPGDEVIVLNSSGELVGVGRLRLSPTEILENECWGEAIRLRKTVKGDNS

Specific function: Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs [H]

COG id: COG1370

COG function: function code O; Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PUA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004804
- InterPro:   IPR002478
- InterPro:   IPR015947
- InterPro:   IPR002616
- InterPro:   IPR004521 [H]

Pfam domain/function: PF01472 PUA; PF01702 TGT [H]

EC number: NA

Molecular weight: Translated: 17803; Mature: 17803

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS50890 PUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIRRARPEEVVRLRAIADYQFGFPAGDLLIPDNVVVGVSPATRRIREIYGEEGLLAVLR
CCCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCEEEECCHHHHHHHHHHCCCCCEEHHH
AHDYLYSLSLLGAKRLLALPEPRLRARLRVETPPSKSINCRIIETIDHDLRPGDEVIVLN
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCCEEEEC
SSGELVGVGRLRLSPTEILENECWGEAIRLRKTVKGDNS
CCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIIRRARPEEVVRLRAIADYQFGFPAGDLLIPDNVVVGVSPATRRIREIYGEEGLLAVLR
CCCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCEEEECCHHHHHHHHHHCCCCCEEHHH
AHDYLYSLSLLGAKRLLALPEPRLRARLRVETPPSKSINCRIIETIDHDLRPGDEVIVLN
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCCEEEEC
SSGELVGVGRLRLSPTEILENECWGEAIRLRKTVKGDNS
CCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA