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The map label for this gene is tldD [C]

Identifier: 124027301

GI number: 124027301

Start: 398542

End: 399921

Strand: Reverse

Name: tldD [C]

Synonym: Hbut_0410

Alternate gene names: 124027301

Gene position: 399921-398542 (Counterclockwise)

Preceding gene: 124027303

Following gene: 124027300

Centisome position: 23.99

GC content: 52.54

Gene sequence:

>1380_bases
TTGCTAGACGATATACGCGACATTCTCGTAAAGGCGCTGGGATTCACTAGCGGGTGGCACATAGATCTTGCCGACATCCG
TGTTGAGAGAATTCAGTTCACCAGAATAGACGTCGAGAACGGCACAGTCAAGATTTCATCGGGCATAGACTATGGTGCGG
CTGTTCGTGTATTCGTAAACGGTGTGATGGGGTTCGCGTTTACAACCAGGGTTACAGTAGATTCGTTAAGGCGAGCCCTA
GAGCAAGCCTACTCCATGGCCTCAGCGCACCGGGAGAAGCTATCCAAACCCCTAACGTTTGAAGCGGTTGAAGACTACTA
TGAGGCTCCGGTTAAGAGGAGTATTGTTGACGTACCAATTGACGCCAAGCTATCCGATGTGCTGGAGCTCGACAAGGCTA
TTGCATCGGCGCCTCAGGTAAAGTCGCGCAGAGTGGTCTACGTAGAGAGGGTCGAGGAGCGCTACTATGCAAGTACCGAG
GACCGCGTGCTGGGCGAGAAGAGAGAGCTAGTATATGTTTATGCCTCGGCATTCGGTGTCGAGGCCGGGGTGCGTGCTGC
AGCTCATGTAACCCAGGGGACGATAAAGGGGTACTATGTCTGGGAGAAGACTAGCCAGGAACAGCTGGCCCAACAGCTAC
TCAAGAGGCTCACAAACCAGTTCAAAGCCAAGACGCCCAAGGCTGGCAACTTCCCAGTAGTATTAGCACCAGAAGCCCTT
GGTGTCTTTGTCCACGAGGCATTTGGCCACCTTGCTGAGGCCGATCTTGTTGTTGCGGGTAGCGCGCTTCAGGGCAAGAA
GGGAGAGAAAGTGGCCTCGGAGCTAGTGACAATAGTTGATGATCCAACTATAGAGGATGGTTTCGGCACGATAAAATACG
ACGATGAGGGCGTGAGGACGGCGCGTGCAGTGATAGTCGAGAGAGGGATACACAAGCAAGTCATGACGGATCGTGTCCAT
GCTGCAATGTTGAATGAGAATCCCACGGGTAATGCTAGGGCAGAATCATTCCGACATGCGCCACTTGTACGTATGAGGAA
TACTGTGCTCCTACCAGGAGACCATAGCGTTGAAGAGGTGTTTGAGGGGATAAGATTTGGCTACTACGTTGTTGCAACTT
CTGGCGGCCAGACAAACATGGATGGAAGTTTCCAGGTGGGCATCGAGGAAGCGTACGAGATAGTAAACGGTGAGGTTGGC
GAACCAGTGCGCAACCTCAGCATAGCTGGTAACACATTGGAAACATTAATGAACATTGATGCTGTAGCGAAGGACTTCAA
GGTGTTCTATGGTCGCTGTGGTAAGGGCCAGCTAGTATACGTATCCGACGGCGGCCCCCACGCACGCGTTAAGAAGATGA
CCGTGGGAGGTCGCGAGTAG

Upstream 100 bases:

>100_bases
GGTAGCAGTGTGTTAATGTAAGAGGCTCTTATAAATACCCCCAGGAACGCTGACAAAACTAATGGTCCTCCCAACCACTG
TTAAAGGGGTCTGGATAGGT

Downstream 100 bases:

>100_bases
GCCTCCATGCATTCCTTTCTGTGTTCACATCTGTTTGAGCCGTGCTATGTGGGGTGTATGGGTGTGTCGGCTCAACGTGT
ACAGCCCGTTGAAGTGGCTG

Product: Zn-dependent protease TldD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MLDDIRDILVKALGFTSGWHIDLADIRVERIQFTRIDVENGTVKISSGIDYGAAVRVFVNGVMGFAFTTRVTVDSLRRAL
EQAYSMASAHREKLSKPLTFEAVEDYYEAPVKRSIVDVPIDAKLSDVLELDKAIASAPQVKSRRVVYVERVEERYYASTE
DRVLGEKRELVYVYASAFGVEAGVRAAAHVTQGTIKGYYVWEKTSQEQLAQQLLKRLTNQFKAKTPKAGNFPVVLAPEAL
GVFVHEAFGHLAEADLVVAGSALQGKKGEKVASELVTIVDDPTIEDGFGTIKYDDEGVRTARAVIVERGIHKQVMTDRVH
AAMLNENPTGNARAESFRHAPLVRMRNTVLLPGDHSVEEVFEGIRFGYYVVATSGGQTNMDGSFQVGIEEAYEIVNGEVG
EPVRNLSIAGNTLETLMNIDAVAKDFKVFYGRCGKGQLVYVSDGGPHARVKKMTVGGRE

Sequences:

>Translated_459_residues
MLDDIRDILVKALGFTSGWHIDLADIRVERIQFTRIDVENGTVKISSGIDYGAAVRVFVNGVMGFAFTTRVTVDSLRRAL
EQAYSMASAHREKLSKPLTFEAVEDYYEAPVKRSIVDVPIDAKLSDVLELDKAIASAPQVKSRRVVYVERVEERYYASTE
DRVLGEKRELVYVYASAFGVEAGVRAAAHVTQGTIKGYYVWEKTSQEQLAQQLLKRLTNQFKAKTPKAGNFPVVLAPEAL
GVFVHEAFGHLAEADLVVAGSALQGKKGEKVASELVTIVDDPTIEDGFGTIKYDDEGVRTARAVIVERGIHKQVMTDRVH
AAMLNENPTGNARAESFRHAPLVRMRNTVLLPGDHSVEEVFEGIRFGYYVVATSGGQTNMDGSFQVGIEEAYEIVNGEVG
EPVRNLSIAGNTLETLMNIDAVAKDFKVFYGRCGKGQLVYVSDGGPHARVKKMTVGGRE
>Mature_459_residues
MLDDIRDILVKALGFTSGWHIDLADIRVERIQFTRIDVENGTVKISSGIDYGAAVRVFVNGVMGFAFTTRVTVDSLRRAL
EQAYSMASAHREKLSKPLTFEAVEDYYEAPVKRSIVDVPIDAKLSDVLELDKAIASAPQVKSRRVVYVERVEERYYASTE
DRVLGEKRELVYVYASAFGVEAGVRAAAHVTQGTIKGYYVWEKTSQEQLAQQLLKRLTNQFKAKTPKAGNFPVVLAPEAL
GVFVHEAFGHLAEADLVVAGSALQGKKGEKVASELVTIVDDPTIEDGFGTIKYDDEGVRTARAVIVERGIHKQVMTDRVH
AAMLNENPTGNARAESFRHAPLVRMRNTVLLPGDHSVEEVFEGIRFGYYVVATSGGQTNMDGSFQVGIEEAYEIVNGEVG
EPVRNLSIAGNTLETLMNIDAVAKDFKVFYGRCGKGQLVYVSDGGPHARVKKMTVGGRE

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=464, Percent_Identity=31.25, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1790682, Length=230, Percent_Identity=27.8260869565217, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 50468; Mature: 50468

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDDIRDILVKALGFTSGWHIDLADIRVERIQFTRIDVENGTVKISSGIDYGAAVRVFVN
CCCHHHHHHHHHHCCCCCCEEEHHHEEEEEEEEEEEEECCCEEEEECCCCCHHHHHHHHH
GVMGFAFTTRVTVDSLRRALEQAYSMASAHREKLSKPLTFEAVEDYYEAPVKRSIVDVPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHCEEECCC
DAKLSDVLELDKAIASAPQVKSRRVVYVERVEERYYASTEDRVLGEKRELVYVYASAFGV
CCHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHCCCCCHHHCCCCCCEEEEEEEHHCH
EAGVRAAAHVTQGTIKGYYVWEKTSQEQLAQQLLKRLTNQFKAKTPKAGNFPVVLAPEAL
HHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCHHH
GVFVHEAFGHLAEADLVVAGSALQGKKGEKVASELVTIVDDPTIEDGFGTIKYDDEGVRT
HHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHH
ARAVIVERGIHKQVMTDRVHAAMLNENPTGNARAESFRHAPLVRMRNTVLLPGDHSVEEV
HHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHCCEEEECCCCCHHHH
FEGIRFGYYVVATSGGQTNMDGSFQVGIEEAYEIVNGEVGEPVRNLSIAGNTLETLMNID
HHHHCCCEEEEEECCCCCCCCCCEEECHHHHHHHHCCCCCCCHHHHEECCHHHHHHHHHH
AVAKDFKVFYGRCGKGQLVYVSDGGPHARVKKMTVGGRE
HHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEECCCCC
>Mature Secondary Structure
MLDDIRDILVKALGFTSGWHIDLADIRVERIQFTRIDVENGTVKISSGIDYGAAVRVFVN
CCCHHHHHHHHHHCCCCCCEEEHHHEEEEEEEEEEEEECCCEEEEECCCCCHHHHHHHHH
GVMGFAFTTRVTVDSLRRALEQAYSMASAHREKLSKPLTFEAVEDYYEAPVKRSIVDVPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHCEEECCC
DAKLSDVLELDKAIASAPQVKSRRVVYVERVEERYYASTEDRVLGEKRELVYVYASAFGV
CCHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHCCCCCHHHCCCCCCEEEEEEEHHCH
EAGVRAAAHVTQGTIKGYYVWEKTSQEQLAQQLLKRLTNQFKAKTPKAGNFPVVLAPEAL
HHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCHHH
GVFVHEAFGHLAEADLVVAGSALQGKKGEKVASELVTIVDDPTIEDGFGTIKYDDEGVRT
HHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHH
ARAVIVERGIHKQVMTDRVHAAMLNENPTGNARAESFRHAPLVRMRNTVLLPGDHSVEEV
HHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHCCEEEECCCCCHHHH
FEGIRFGYYVVATSGGQTNMDGSFQVGIEEAYEIVNGEVGEPVRNLSIAGNTLETLMNID
HHHHCCCEEEEEECCCCCCCCCCEEECHHHHHHHHCCCCCCCHHHHEECCHHHHHHHHHH
AVAKDFKVFYGRCGKGQLVYVSDGGPHARVKKMTVGGRE
HHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]