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The map label for this gene is carB

Identifier: 124027199

GI number: 124027199

Start: 287494

End: 290715

Strand: Reverse

Name: carB

Synonym: Hbut_0302

Alternate gene names: 124027199

Gene position: 290715-287494 (Counterclockwise)

Preceding gene: 124027200

Following gene: 124027198

Centisome position: 17.44

GC content: 60.77

Gene sequence:

>3222_bases
ATGCCTAGGAGGATAGATGTTAGGAAGGTACTGATGCTGGGCAGCGGCGCCATAAAGATAGCTGAGGCTGCAGAGTTCGA
CTATAGTGGCAGTCAGGCGCTGAAAGCCCTGCGCGAGGAGGGTATAGAGACGGTACTGGTAAACCCGAACGTTGCAACCA
TTCAGACGAGCTACAAGCTCGCAGACCATGTCTACCTTGGCCCTCTCCAGCCATGGTTTGTCGAGAAGGTTATTGAGCGC
GAGCGGCCGGACGCGATACTGCTAGGCTTCGGTGGCCAGACAGCGCTTAGCCTTGGCGTGGAGCTGCACCGCCGTGGTAT
CCTGAGCCGGTACGGGATCCGGGTCCTGGGCACCCCTATAGAGGGTATTGAGAAGGCTCTCTCGCGCGGCAAGTTCCGCG
AAACCATGATGAAGGCTGGCCTCCCGGTTCCACCCAGCACCCCTGCCACGAGCGTCGAGGAGGCGCTTAGGGCTGCCAAC
GAGATAGGATACCCGGTCATAGTCCGCGTCAGCTTCAACCTCGGCGGTGGCGGAAGCCTAGTAGCCTGGAGCCGCGAGGA
GCTGGAGCGCTGGCTTGTTCGCGCCTTCGCGTTCTCTGGCACTGGCGAGGTCCTCGTCGAGAAGTACCTCCACTACTGGA
AGGAGATAGAGTACGAGGTTGTACGCGACCAGTATGGCAACATGGTTGCAGTAGCATGCCTCGAGAACGCCGACCCAATG
GGCGTCCACACGGGAGAATCCGTGGTCATAGCTCCGTGCCAGACGCTCACCGACCAGGAGTACCAGCTGCTGCGCGAGGC
AAGCCTGCGTGTTGCCGAAGCTATAGGCCTCGTGGGAGAGGGTAACGTGCAGCTGGCGCTCAACCCCCGTGACAGCTGGG
AGTACTATGTGATAGAGACTAACCCGCGTATGAGCCGTAGCAGCGCCCTGGCGAGCAAGGCGACGGGCTACCCGCTAGCA
TACATTGCTGCAAAGCTCGCACTCGGCTACCGGCTCGACGAGCTACTAAACCGTGTCACTGAGAGGACGTGCGCCTGCTT
CGAGCCAAGCCTAGACTACGTCGTAGTTAAGGTGCCACGATGGGACCTGGAGAAGTTCGAGGGCGTGGAGAAGAGTATTG
GCAGCGAAATGAAGAGCATAGGCGAGGTAATGGCGATAGGTAGAAACTTCGCCGAGGCGCTCCAGAAGGCTATACGCATG
CTCGACATAGGAGAACCGGGGGTCGTCGCAGGCCCGAGGTACGAGGAGCCTGAGAGTCTAGAGGAGGTTCTAGGCAAGCT
GCGGCGCCGAGAGCCATACTGGCCCATATGGGCTGCGAAAGCATTCAGGCTCGGAGCTAGCGTCGAGCAGGTCTACGAGG
CTACCGGTGTAGACCCCTACTTCCTCAGCCAGATACGCGAGATCGTGGAGGTCGCGGAGAAGCTGCGGCGCACAAAGCCC
TGGAGCTCCGAGTTCCTCGACCTGCTTGCTGAGGCTAAACGGCTAGGCTTTAGCGACGAGCAGGTGGCACTGCTCACCGG
CACCACTGTTGAGAAGGTAGAGAAGGCACGTAGAAGCATAGGTCTCGACAGGCCCCGCGTCAGGCAGATCGACACGCTCG
CAGCCGAGTGGCCTGCAGCGACAAACTATCTCTACATGAGCTACAATGCCTACGAGGATGACGAGCCCATAACAACTGGC
CGCCCCAGGCTCATTGTGCTGGGTGCTGGCGTATTCCGTATTGGTGTCTCGGTCGAGTTCGACTGGGGCGTAGTAAGCTT
CGCCGATGAGGCGCGCCGCCTCGGCTACGAGGTGGTAATAGTCAACTACAACCCCGAGACGGTATCCACAGACTGGGATA
TAAGCGACAAGCTGTACTTCGAGGAGCTAACCCTCGAAAGGGTCATCGACATATACTGGTTCGAGAAGCCGGTCGGCGTG
ATAGCCTTCCTCGGCGGCCAGATAGCAAACAATCTCGCCAAGCCGCTGGAGGAGCGCGGCGTCAGACTCCTCGGCACACC
GGGCAGGAGTGTGGACCGAGCCGAGAACCGCGCTTGGTTCTCCCAGCTCCTCGAGGAGCTGGGCATAAAGCAGCCGAGCT
GGACAGCAGCCTCGAGCATCGAGGAGGTTCTAAAGTTCGCGGAGAGCGTGGGCTACCCGGTCCTGGTGCGTCCAAGCTAC
GTGCTAAGTGGCTCAGCGATGAAGATCGCGTGGAGCCCCGAGGAGCTGAAGAGCTACATAGAGCAGGCCGCAAGGGTGTC
GCCACGCTACCCAGTGGTTGTCTCCAAGTTCCTCGAGGACGCTGTAGAGGCGGAGATAGACGCTGTCGGTGATAGCCGCC
GCACGGTGGGCACTGTGATAGAGCACGTTGAGCCTGGCGGTGTGCACAGCGGCGACTCGACAATGGTTATCCCCTGGTTC
AGCCTGCCTGAGACAGCTGTGCGGGAGATGATACGCATAGCAGAGACCCTCAACGAGGTGCTAGAAATCAAGGGCCCATT
CAACATACAGTTCCTAGTCAAGGATGGTAGCGTCTACGTGGTCGAGCTAAACCTCCGCGCAAGCCGATCAATGCCCTTCA
CAAGCAAGGTCACCGGCTACAACCTCATGCGCGCAGCTGCCGAAGCAGCACTCAGGGGAAGGATAAGCTACGGCTTCAAC
GGGGCCGACGGCTTCAAGCTGCTGAGGCCCACCGGGTGGTGGGGCGTCAAGAGCCCCCAGCCGAGCTGGCAGAGGCTCCG
GGGCGCCTATCCAGGCCTAGGCCCCGAGATGAGGAGCACCGGCGAGGTAGCAGCGCTCGGCCGCACACTCCACGAAGCCC
TGCTCAAGAGCTGGCTGAGCGTCCAGGGCAACAGGATACCCCCGGCCGGCAGCATAGTACTCATATACACGCCGACTGGC
AGGGGCAGCAGCGACCTATCCCAGGCAGCGAAGCTGATGACGGAGAAGGGCTACACGGTATACACCATAGAGGGCATGGA
GGTGGATGGTGCTGAGCCGCTGCCGCTGGAGCAGGCACTACGCCTCGTAAGGATGGGCGGTGTAGGCCTCCTAATGACCA
CGGACTATGCGCCACAGCGCGACTACAGGGTGCGCCGCCTAGCGGTAGACCTTGGGGTGCCCGTGGTGCTCGACGCACGG
CTAGCCAGGATGCTCGCCGAGGCCATCAACCGGGTAGGCCTGGAGAATCTCGAGGCGCTCGAGCTACGCGAGTACTGGGG
CCCCAACGTGGAGCCATTCTAG

Upstream 100 bases:

>100_bases
CTCCACATGGGTTTTCGACTTGTTCCTCAAGCTCATCGAGGAGACCAAGTCTCGACAAGCCGTCTAGCCCTGATGGTGCA
TGGCAAGGGGTGGCTGTGGA

Downstream 100 bases:

>100_bases
CATCCAGTACACGCGCTGCCGGCTTGATGATTTTAGAGGAGAATGGGTGTGCTCCGGCCGCAGCCGGGCCTGACTCCCCG
TAGTAGTGAGCATCGCTGGA

Product: carbamoyl phosphate synthase large subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase ammonia chain

Number of amino acids: Translated: 1073; Mature: 1072

Protein sequence:

>1073_residues
MPRRIDVRKVLMLGSGAIKIAEAAEFDYSGSQALKALREEGIETVLVNPNVATIQTSYKLADHVYLGPLQPWFVEKVIER
ERPDAILLGFGGQTALSLGVELHRRGILSRYGIRVLGTPIEGIEKALSRGKFRETMMKAGLPVPPSTPATSVEEALRAAN
EIGYPVIVRVSFNLGGGGSLVAWSREELERWLVRAFAFSGTGEVLVEKYLHYWKEIEYEVVRDQYGNMVAVACLENADPM
GVHTGESVVIAPCQTLTDQEYQLLREASLRVAEAIGLVGEGNVQLALNPRDSWEYYVIETNPRMSRSSALASKATGYPLA
YIAAKLALGYRLDELLNRVTERTCACFEPSLDYVVVKVPRWDLEKFEGVEKSIGSEMKSIGEVMAIGRNFAEALQKAIRM
LDIGEPGVVAGPRYEEPESLEEVLGKLRRREPYWPIWAAKAFRLGASVEQVYEATGVDPYFLSQIREIVEVAEKLRRTKP
WSSEFLDLLAEAKRLGFSDEQVALLTGTTVEKVEKARRSIGLDRPRVRQIDTLAAEWPAATNYLYMSYNAYEDDEPITTG
RPRLIVLGAGVFRIGVSVEFDWGVVSFADEARRLGYEVVIVNYNPETVSTDWDISDKLYFEELTLERVIDIYWFEKPVGV
IAFLGGQIANNLAKPLEERGVRLLGTPGRSVDRAENRAWFSQLLEELGIKQPSWTAASSIEEVLKFAESVGYPVLVRPSY
VLSGSAMKIAWSPEELKSYIEQAARVSPRYPVVVSKFLEDAVEAEIDAVGDSRRTVGTVIEHVEPGGVHSGDSTMVIPWF
SLPETAVREMIRIAETLNEVLEIKGPFNIQFLVKDGSVYVVELNLRASRSMPFTSKVTGYNLMRAAAEAALRGRISYGFN
GADGFKLLRPTGWWGVKSPQPSWQRLRGAYPGLGPEMRSTGEVAALGRTLHEALLKSWLSVQGNRIPPAGSIVLIYTPTG
RGSSDLSQAAKLMTEKGYTVYTIEGMEVDGAEPLPLEQALRLVRMGGVGLLMTTDYAPQRDYRVRRLAVDLGVPVVLDAR
LARMLAEAINRVGLENLEALELREYWGPNVEPF

Sequences:

>Translated_1073_residues
MPRRIDVRKVLMLGSGAIKIAEAAEFDYSGSQALKALREEGIETVLVNPNVATIQTSYKLADHVYLGPLQPWFVEKVIER
ERPDAILLGFGGQTALSLGVELHRRGILSRYGIRVLGTPIEGIEKALSRGKFRETMMKAGLPVPPSTPATSVEEALRAAN
EIGYPVIVRVSFNLGGGGSLVAWSREELERWLVRAFAFSGTGEVLVEKYLHYWKEIEYEVVRDQYGNMVAVACLENADPM
GVHTGESVVIAPCQTLTDQEYQLLREASLRVAEAIGLVGEGNVQLALNPRDSWEYYVIETNPRMSRSSALASKATGYPLA
YIAAKLALGYRLDELLNRVTERTCACFEPSLDYVVVKVPRWDLEKFEGVEKSIGSEMKSIGEVMAIGRNFAEALQKAIRM
LDIGEPGVVAGPRYEEPESLEEVLGKLRRREPYWPIWAAKAFRLGASVEQVYEATGVDPYFLSQIREIVEVAEKLRRTKP
WSSEFLDLLAEAKRLGFSDEQVALLTGTTVEKVEKARRSIGLDRPRVRQIDTLAAEWPAATNYLYMSYNAYEDDEPITTG
RPRLIVLGAGVFRIGVSVEFDWGVVSFADEARRLGYEVVIVNYNPETVSTDWDISDKLYFEELTLERVIDIYWFEKPVGV
IAFLGGQIANNLAKPLEERGVRLLGTPGRSVDRAENRAWFSQLLEELGIKQPSWTAASSIEEVLKFAESVGYPVLVRPSY
VLSGSAMKIAWSPEELKSYIEQAARVSPRYPVVVSKFLEDAVEAEIDAVGDSRRTVGTVIEHVEPGGVHSGDSTMVIPWF
SLPETAVREMIRIAETLNEVLEIKGPFNIQFLVKDGSVYVVELNLRASRSMPFTSKVTGYNLMRAAAEAALRGRISYGFN
GADGFKLLRPTGWWGVKSPQPSWQRLRGAYPGLGPEMRSTGEVAALGRTLHEALLKSWLSVQGNRIPPAGSIVLIYTPTG
RGSSDLSQAAKLMTEKGYTVYTIEGMEVDGAEPLPLEQALRLVRMGGVGLLMTTDYAPQRDYRVRRLAVDLGVPVVLDAR
LARMLAEAINRVGLENLEALELREYWGPNVEPF
>Mature_1072_residues
PRRIDVRKVLMLGSGAIKIAEAAEFDYSGSQALKALREEGIETVLVNPNVATIQTSYKLADHVYLGPLQPWFVEKVIERE
RPDAILLGFGGQTALSLGVELHRRGILSRYGIRVLGTPIEGIEKALSRGKFRETMMKAGLPVPPSTPATSVEEALRAANE
IGYPVIVRVSFNLGGGGSLVAWSREELERWLVRAFAFSGTGEVLVEKYLHYWKEIEYEVVRDQYGNMVAVACLENADPMG
VHTGESVVIAPCQTLTDQEYQLLREASLRVAEAIGLVGEGNVQLALNPRDSWEYYVIETNPRMSRSSALASKATGYPLAY
IAAKLALGYRLDELLNRVTERTCACFEPSLDYVVVKVPRWDLEKFEGVEKSIGSEMKSIGEVMAIGRNFAEALQKAIRML
DIGEPGVVAGPRYEEPESLEEVLGKLRRREPYWPIWAAKAFRLGASVEQVYEATGVDPYFLSQIREIVEVAEKLRRTKPW
SSEFLDLLAEAKRLGFSDEQVALLTGTTVEKVEKARRSIGLDRPRVRQIDTLAAEWPAATNYLYMSYNAYEDDEPITTGR
PRLIVLGAGVFRIGVSVEFDWGVVSFADEARRLGYEVVIVNYNPETVSTDWDISDKLYFEELTLERVIDIYWFEKPVGVI
AFLGGQIANNLAKPLEERGVRLLGTPGRSVDRAENRAWFSQLLEELGIKQPSWTAASSIEEVLKFAESVGYPVLVRPSYV
LSGSAMKIAWSPEELKSYIEQAARVSPRYPVVVSKFLEDAVEAEIDAVGDSRRTVGTVIEHVEPGGVHSGDSTMVIPWFS
LPETAVREMIRIAETLNEVLEIKGPFNIQFLVKDGSVYVVELNLRASRSMPFTSKVTGYNLMRAAAEAALRGRISYGFNG
ADGFKLLRPTGWWGVKSPQPSWQRLRGAYPGLGPEMRSTGEVAALGRTLHEALLKSWLSVQGNRIPPAGSIVLIYTPTGR
GSSDLSQAAKLMTEKGYTVYTIEGMEVDGAEPLPLEQALRLVRMGGVGLLMTTDYAPQRDYRVRRLAVDLGVPVVLDARL
ARMLAEAINRVGLENLEALELREYWGPNVEPF

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0458

COG function: function code EF; Carbamoylphosphate synthase large subunit (split gene in MJ)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ATP-grasp domains

Homologues:

Organism=Homo sapiens, GI18105007, Length=1079, Percent_Identity=47.451343836886, Blast_Score=912, Evalue=0.0,
Organism=Homo sapiens, GI21361331, Length=1088, Percent_Identity=44.8529411764706, Blast_Score=882, Evalue=0.0,
Organism=Homo sapiens, GI169790915, Length=1088, Percent_Identity=44.8529411764706, Blast_Score=881, Evalue=0.0,
Organism=Homo sapiens, GI170295797, Length=1055, Percent_Identity=44.1706161137441, Blast_Score=840, Evalue=0.0,
Organism=Homo sapiens, GI106049528, Length=356, Percent_Identity=27.8089887640449, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI106049295, Length=356, Percent_Identity=27.8089887640449, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI106049292, Length=356, Percent_Identity=27.8089887640449, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI295821183, Length=317, Percent_Identity=24.9211356466877, Blast_Score=71, Evalue=6e-12,
Organism=Homo sapiens, GI189095269, Length=319, Percent_Identity=24.7648902821317, Blast_Score=71, Evalue=6e-12,
Organism=Homo sapiens, GI65506442, Length=319, Percent_Identity=24.7648902821317, Blast_Score=71, Evalue=7e-12,
Organism=Homo sapiens, GI116805327, Length=339, Percent_Identity=23.3038348082596, Blast_Score=70, Evalue=9e-12,
Organism=Escherichia coli, GI1786216, Length=943, Percent_Identity=44.644750795334, Blast_Score=781, Evalue=0.0,
Organism=Caenorhabditis elegans, GI193204318, Length=1088, Percent_Identity=44.1176470588235, Blast_Score=850, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17562816, Length=290, Percent_Identity=25.8620689655172, Blast_Score=76, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71987519, Length=314, Percent_Identity=27.3885350318471, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322331, Length=1083, Percent_Identity=45.0600184672207, Blast_Score=870, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6322569, Length=1097, Percent_Identity=43.482224247949, Blast_Score=839, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319695, Length=276, Percent_Identity=26.0869565217391, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6321376, Length=300, Percent_Identity=25.6666666666667, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24642586, Length=1082, Percent_Identity=45.8410351201479, Blast_Score=897, Evalue=0.0,
Organism=Drosophila melanogaster, GI45555749, Length=983, Percent_Identity=48.3214649033571, Blast_Score=884, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=344, Percent_Identity=26.7441860465116, Blast_Score=84, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24652224, Length=344, Percent_Identity=26.7441860465116, Blast_Score=84, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24652222, Length=344, Percent_Identity=26.7441860465116, Blast_Score=84, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24652220, Length=344, Percent_Identity=26.7441860465116, Blast_Score=84, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24652218, Length=344, Percent_Identity=26.7441860465116, Blast_Score=84, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24652212, Length=344, Percent_Identity=26.7441860465116, Blast_Score=84, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24652210, Length=344, Percent_Identity=26.7441860465116, Blast_Score=84, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24652214, Length=344, Percent_Identity=26.7441860465116, Blast_Score=84, Evalue=7e-16,
Organism=Drosophila melanogaster, GI19921944, Length=344, Percent_Identity=26.7441860465116, Blast_Score=84, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24652216, Length=344, Percent_Identity=26.7441860465116, Blast_Score=84, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24651757, Length=331, Percent_Identity=26.2839879154079, Blast_Score=78, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24651759, Length=275, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=3e-13,

Paralogues:

None

Copy number: 4701 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): CARB_HYPBU (A2BJL3)

Other databases:

- EMBL:   CP000493
- RefSeq:   YP_001012519.1
- ProteinModelPortal:   A2BJL3
- STRING:   A2BJL3
- GeneID:   4781404
- GenomeReviews:   CP000493_GR
- KEGG:   hbu:Hbut_0302
- eggNOG:   arNOG04624
- HOGENOM:   HBG405439
- OMA:   MNRIGEP
- PhylomeDB:   A2BJL3
- ProtClustDB:   PRK05294
- BioCyc:   HBUT415426:HBUT_0302-MONOMER
- HAMAP:   MF_01210_A
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR006275
- InterPro:   IPR005479
- InterPro:   IPR005483
- InterPro:   IPR005481
- InterPro:   IPR005480
- InterPro:   IPR013817
- InterPro:   IPR016185
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:1.10.1030.10
- Gene3D:   G3DSA:3.40.50.20
- PRINTS:   PR00098
- TIGRFAMs:   TIGR01369

Pfam domain/function: PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF02787 CPSase_L_D3; SSF48108 CarbamoylP_synth_lsu_oligo; SSF52440 PreATP-grasp-like

EC number: =6.3.5.5

Molecular weight: Translated: 119164; Mature: 119033

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50975 ATP_GRASP; PS00866 CPSASE_1; PS00867 CPSASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRRIDVRKVLMLGSGAIKIAEAAEFDYSGSQALKALREEGIETVLVNPNVATIQTSYKL
CCCCCCHHHHHEECCCCEEEEHHCCCCCCHHHHHHHHHHCCCCEEEECCCEEEEEEHHHH
ADHVYLGPLQPWFVEKVIERERPDAILLGFGGQTALSLGVELHRRGILSRYGIRVLGTPI
HCEEEECCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEECCCH
EGIEKALSRGKFRETMMKAGLPVPPSTPATSVEEALRAANEIGYPVIVRVSFNLGGGGSL
HHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEEECCCCCCE
VAWSREELERWLVRAFAFSGTGEVLVEKYLHYWKEIEYEVVRDQYGNMVAVACLENADPM
EEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCC
GVHTGESVVIAPCQTLTDQEYQLLREASLRVAEAIGLVGEGNVQLALNPRDSWEYYVIET
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEC
NPRMSRSSALASKATGYPLAYIAAKLALGYRLDELLNRVTERTCACFEPSLDYVVVKVPR
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
WDLEKFEGVEKSIGSEMKSIGEVMAIGRNFAEALQKAIRMLDIGEPGVVAGPRYEEPESL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
EEVLGKLRRREPYWPIWAAKAFRLGASVEQVYEATGVDPYFLSQIREIVEVAEKLRRTKP
HHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
WSSEFLDLLAEAKRLGFSDEQVALLTGTTVEKVEKARRSIGLDRPRVRQIDTLAAEWPAA
CHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCC
TNYLYMSYNAYEDDEPITTGRPRLIVLGAGVFRIGVSVEFDWGVVSFADEARRLGYEVVI
CCEEEEEECCCCCCCCCCCCCCEEEEEECCEEEEEEEEEECCCHHHHHHHHHHCCEEEEE
VNYNPETVSTDWDISDKLYFEELTLERVIDIYWFEKPVGVIAFLGGQIANNLAKPLEERG
EEECCCEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
VRLLGTPGRSVDRAENRAWFSQLLEELGIKQPSWTAASSIEEVLKFAESVGYPVLVRPSY
CEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCE
VLSGSAMKIAWSPEELKSYIEQAARVSPRYPVVVSKFLEDAVEAEIDAVGDSRRTVGTVI
EECCCEEEEEECHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EHVEPGGVHSGDSTMVIPWFSLPETAVREMIRIAETLNEVLEIKGPFNIQFLVKDGSVYV
HHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEE
VELNLRASRSMPFTSKVTGYNLMRAAAEAALRGRISYGFNGADGFKLLRPTGWWGVKSPQ
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCC
PSWQRLRGAYPGLGPEMRSTGEVAALGRTLHEALLKSWLSVQGNRIPPAGSIVLIYTPTG
CHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCC
RGSSDLSQAAKLMTEKGYTVYTIEGMEVDGAEPLPLEQALRLVRMGGVGLLMTTDYAPQR
CCCHHHHHHHHHHHCCCCEEEEEECEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCCCC
DYRVRRLAVDLGVPVVLDARLARMLAEAINRVGLENLEALELREYWGPNVEPF
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PRRIDVRKVLMLGSGAIKIAEAAEFDYSGSQALKALREEGIETVLVNPNVATIQTSYKL
CCCCCHHHHHEECCCCEEEEHHCCCCCCHHHHHHHHHHCCCCEEEECCCEEEEEEHHHH
ADHVYLGPLQPWFVEKVIERERPDAILLGFGGQTALSLGVELHRRGILSRYGIRVLGTPI
HCEEEECCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEECCCH
EGIEKALSRGKFRETMMKAGLPVPPSTPATSVEEALRAANEIGYPVIVRVSFNLGGGGSL
HHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEEECCCCCCE
VAWSREELERWLVRAFAFSGTGEVLVEKYLHYWKEIEYEVVRDQYGNMVAVACLENADPM
EEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCC
GVHTGESVVIAPCQTLTDQEYQLLREASLRVAEAIGLVGEGNVQLALNPRDSWEYYVIET
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEC
NPRMSRSSALASKATGYPLAYIAAKLALGYRLDELLNRVTERTCACFEPSLDYVVVKVPR
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
WDLEKFEGVEKSIGSEMKSIGEVMAIGRNFAEALQKAIRMLDIGEPGVVAGPRYEEPESL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
EEVLGKLRRREPYWPIWAAKAFRLGASVEQVYEATGVDPYFLSQIREIVEVAEKLRRTKP
HHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
WSSEFLDLLAEAKRLGFSDEQVALLTGTTVEKVEKARRSIGLDRPRVRQIDTLAAEWPAA
CHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCC
TNYLYMSYNAYEDDEPITTGRPRLIVLGAGVFRIGVSVEFDWGVVSFADEARRLGYEVVI
CCEEEEEECCCCCCCCCCCCCCEEEEEECCEEEEEEEEEECCCHHHHHHHHHHCCEEEEE
VNYNPETVSTDWDISDKLYFEELTLERVIDIYWFEKPVGVIAFLGGQIANNLAKPLEERG
EEECCCEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
VRLLGTPGRSVDRAENRAWFSQLLEELGIKQPSWTAASSIEEVLKFAESVGYPVLVRPSY
CEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCE
VLSGSAMKIAWSPEELKSYIEQAARVSPRYPVVVSKFLEDAVEAEIDAVGDSRRTVGTVI
EECCCEEEEEECHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EHVEPGGVHSGDSTMVIPWFSLPETAVREMIRIAETLNEVLEIKGPFNIQFLVKDGSVYV
HHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEE
VELNLRASRSMPFTSKVTGYNLMRAAAEAALRGRISYGFNGADGFKLLRPTGWWGVKSPQ
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCC
PSWQRLRGAYPGLGPEMRSTGEVAALGRTLHEALLKSWLSVQGNRIPPAGSIVLIYTPTG
CHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCC
RGSSDLSQAAKLMTEKGYTVYTIEGMEVDGAEPLPLEQALRLVRMGGVGLLMTTDYAPQR
CCCHHHHHHHHHHHCCCCEEEEEECEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCCCC
DYRVRRLAVDLGVPVVLDARLARMLAEAINRVGLENLEALELREYWGPNVEPF
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA