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The map label for this gene is 124027133

Identifier: 124027133

GI number: 124027133

Start: 222741

End: 224360

Strand: Direct

Name: 124027133

Synonym: Hbut_0236

Alternate gene names: NA

Gene position: 222741-224360 (Clockwise)

Preceding gene: 124027132

Following gene: 124027135

Centisome position: 13.36

GC content: 57.28

Gene sequence:

>1620_bases
TTGCAGTCGGCTAGGGTTGAGGCTAGGGAGGTCGTCTACCTCCTTCAGCCGCTGCCGTTCACGGGTAAGATACGTGACGC
CATATACGGCGATATAGACTATGTGAAGGATGCAGAGGACCTAATCTTCGACTCTTGGCCTGTCCAGAGGCTCCGCTACA
TATACCAGCTTCAGCTGGCCCACCTCGTCTACCCCTCGGCAACCCATACAAGGTTTAGCCACAGCCTAGGCGTAATGCAT
CTAGCATACCGCTTCATGCACCGCATAGTCTCCCAGCTGCAGGAGAAGGCTCTCCGGGAGCCCGGCAGCCTCTACAACAT
ATTCCTCGAGAAGCCCCGCGAACTCCTCCTAGCAGCGCGTATCGCCGGGCTACTCCACGACATCGGCCACGGGCCTTTTA
GCCACGCCTTCGACTACTACGTGCTCTCTCGCCATGACGTAGTCGGGTTTAGGGTTGGGAACCACGAGATATTGAGCTAT
GTGCTGTACCGGTTCCAGCTCCGCGACACCGTGCGCAGGGCAGCGGAGGGTATGGGGCTTGACGGGGAGCTTGTAGTATC
GCTAGTCGACGAGGCTATGAAGCCGCCGAGGGATAACAAGGAGTACACAGACCTCGCCAATAGCGGGGGGTTCGCTGCTG
GGCTTAGTGGTGAAGACTTCTACCAGCCCCACCCCGACATGGAGCCCCATAAGCTCGTCCGGCTTGTGGTGAGGGACTTT
CTCTACCCAGCCGACATAATGGACTATCTTATACGCGACAGTTACTTCACGCAGGCACCGATAGGCTCTATTGACGTGCA
GAGGCTGATAGGCGAGACGTACGTCGTGGAGTATCATGAGCAGCTATGGCCGGCTATTTCAAGGAAGGCTGTGGATAACC
TTGTAAGGCTTCTCAATGCTCGTAAGCTGATGTATAAGAACGTGTACCTACACCCCGTTAACAAGGCTTTCGACCACACC
CTAGGCATGGTGTTTAACCGGTGTAACGCGTTGAGCACCATGATTGCTGAGGCGCTTGACGCGATGCTCCGGGAGGGCAG
GCTCGAGAGGTATAGGGGCCTCACAGACTACACAATCTACGGCATGTTGAGCTACTGGCTTGCGACCGGCAGACTCCACG
ACGAGTGTAGTGATAGCCAAGCAGCTGAGGCTGTGAAGTCGCTGCTGGACTACCGGAAGCCCCTCTGGAAGTGGGTGCAG
AGGCTCTCAATACCCGAGGATAAGGCTGGCCACCTAGCCCGCGGGAAGAAGGCTGTCTACGAACAGCAGTTGGCACGAGA
TTTCGCCGAACATGCTGGCATCGACCCAGAGGAGGTTCTAGTGGATATTGGGAGGGTTAGCGCATACTCCTCCTCCGCGA
CCACTATAACCCCGTACGTCTTCATAGCCGATACTGTCGGGGGTAGAGTGGCAGCGCCGGAGCCGAAGACGCTGGATCAG
TTCCTCCATGAGCACCGGGTTGCCGGGGAGGTCATAGTGACGTTCTACGTTGAGCGAACCAGGTACCGCAAGCTGAGGGA
TGACAGTGGGGCCATGAGGAGGCTTGCAGAGGCTGCCAAGAGGGCACTCCACGACTATGTCCCAGAGGCGCCGATCCGGG
AGATGGTTGAAACCTCCTAG

Upstream 100 bases:

>100_bases
CTTCTTCGCCGTGGCTTCGGGGAGGCTCGCAGGCTGTGGTAATACCTTTAAGGCTTCTGCATAGGTAATACTCTTCAGGG
ACTGGTAGGGGCAGAGGCCG

Downstream 100 bases:

>100_bases
CCCGCGCGTGCGAGGAAGATGCTCCAAGCCTCCCGTATGAGGCGGGCGCCGTTAATCTCTGCTCTCGGCCGTGCTGTCAG
CTCCGCGGGTTCCAGTACTC

Product: HD superfamily phosphohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MQSARVEAREVVYLLQPLPFTGKIRDAIYGDIDYVKDAEDLIFDSWPVQRLRYIYQLQLAHLVYPSATHTRFSHSLGVMH
LAYRFMHRIVSQLQEKALREPGSLYNIFLEKPRELLLAARIAGLLHDIGHGPFSHAFDYYVLSRHDVVGFRVGNHEILSY
VLYRFQLRDTVRRAAEGMGLDGELVVSLVDEAMKPPRDNKEYTDLANSGGFAAGLSGEDFYQPHPDMEPHKLVRLVVRDF
LYPADIMDYLIRDSYFTQAPIGSIDVQRLIGETYVVEYHEQLWPAISRKAVDNLVRLLNARKLMYKNVYLHPVNKAFDHT
LGMVFNRCNALSTMIAEALDAMLREGRLERYRGLTDYTIYGMLSYWLATGRLHDECSDSQAAEAVKSLLDYRKPLWKWVQ
RLSIPEDKAGHLARGKKAVYEQQLARDFAEHAGIDPEEVLVDIGRVSAYSSSATTITPYVFIADTVGGRVAAPEPKTLDQ
FLHEHRVAGEVIVTFYVERTRYRKLRDDSGAMRRLAEAAKRALHDYVPEAPIREMVETS

Sequences:

>Translated_539_residues
MQSARVEAREVVYLLQPLPFTGKIRDAIYGDIDYVKDAEDLIFDSWPVQRLRYIYQLQLAHLVYPSATHTRFSHSLGVMH
LAYRFMHRIVSQLQEKALREPGSLYNIFLEKPRELLLAARIAGLLHDIGHGPFSHAFDYYVLSRHDVVGFRVGNHEILSY
VLYRFQLRDTVRRAAEGMGLDGELVVSLVDEAMKPPRDNKEYTDLANSGGFAAGLSGEDFYQPHPDMEPHKLVRLVVRDF
LYPADIMDYLIRDSYFTQAPIGSIDVQRLIGETYVVEYHEQLWPAISRKAVDNLVRLLNARKLMYKNVYLHPVNKAFDHT
LGMVFNRCNALSTMIAEALDAMLREGRLERYRGLTDYTIYGMLSYWLATGRLHDECSDSQAAEAVKSLLDYRKPLWKWVQ
RLSIPEDKAGHLARGKKAVYEQQLARDFAEHAGIDPEEVLVDIGRVSAYSSSATTITPYVFIADTVGGRVAAPEPKTLDQ
FLHEHRVAGEVIVTFYVERTRYRKLRDDSGAMRRLAEAAKRALHDYVPEAPIREMVETS
>Mature_539_residues
MQSARVEAREVVYLLQPLPFTGKIRDAIYGDIDYVKDAEDLIFDSWPVQRLRYIYQLQLAHLVYPSATHTRFSHSLGVMH
LAYRFMHRIVSQLQEKALREPGSLYNIFLEKPRELLLAARIAGLLHDIGHGPFSHAFDYYVLSRHDVVGFRVGNHEILSY
VLYRFQLRDTVRRAAEGMGLDGELVVSLVDEAMKPPRDNKEYTDLANSGGFAAGLSGEDFYQPHPDMEPHKLVRLVVRDF
LYPADIMDYLIRDSYFTQAPIGSIDVQRLIGETYVVEYHEQLWPAISRKAVDNLVRLLNARKLMYKNVYLHPVNKAFDHT
LGMVFNRCNALSTMIAEALDAMLREGRLERYRGLTDYTIYGMLSYWLATGRLHDECSDSQAAEAVKSLLDYRKPLWKWVQ
RLSIPEDKAGHLARGKKAVYEQQLARDFAEHAGIDPEEVLVDIGRVSAYSSSATTITPYVFIADTVGGRVAAPEPKTLDQ
FLHEHRVAGEVIVTFYVERTRYRKLRDDSGAMRRLAEAAKRALHDYVPEAPIREMVETS

Specific function: Unknown

COG id: COG1078

COG function: function code R; HD superfamily phosphohydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HD domain [H]

Homologues:

Organism=Homo sapiens, GI38016914, Length=362, Percent_Identity=26.7955801104972, Blast_Score=89, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17537827, Length=346, Percent_Identity=27.4566473988439, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17537829, Length=346, Percent_Identity=27.4566473988439, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003607
- InterPro:   IPR006675
- InterPro:   IPR011991 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 61730; Mature: 61730

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSARVEAREVVYLLQPLPFTGKIRDAIYGDIDYVKDAEDLIFDSWPVQRLRYIYQLQLA
CCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHCCHHHHHHCCCHHHHHHHHHHHHHH
HLVYPSATHTRFSHSLGVMHLAYRFMHRIVSQLQEKALREPGSLYNIFLEKPRELLLAAR
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
IAGLLHDIGHGPFSHAFDYYVLSRHDVVGFRVGNHEILSYVLYRFQLRDTVRRAAEGMGL
HHHHHHHHCCCCHHHHHHHHHEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCC
DGELVVSLVDEAMKPPRDNKEYTDLANSGGFAAGLSGEDFYQPHPDMEPHKLVRLVVRDF
CHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHH
LYPADIMDYLIRDSYFTQAPIGSIDVQRLIGETYVVEYHEQLWPAISRKAVDNLVRLLNA
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKLMYKNVYLHPVNKAFDHTLGMVFNRCNALSTMIAEALDAMLREGRLERYRGLTDYTIY
HHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHH
GMLSYWLATGRLHDECSDSQAAEAVKSLLDYRKPLWKWVQRLSIPEDKAGHLARGKKAVY
HHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
EQQLARDFAEHAGIDPEEVLVDIGRVSAYSSSATTITPYVFIADTVGGRVAAPEPKTLDQ
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEECCEEEEEECCCCCCCCCCCHHHHH
FLHEHRVAGEVIVTFYVERTRYRKLRDDSGAMRRLAEAAKRALHDYVPEAPIREMVETS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCC
>Mature Secondary Structure
MQSARVEAREVVYLLQPLPFTGKIRDAIYGDIDYVKDAEDLIFDSWPVQRLRYIYQLQLA
CCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHCCHHHHHHCCCHHHHHHHHHHHHHH
HLVYPSATHTRFSHSLGVMHLAYRFMHRIVSQLQEKALREPGSLYNIFLEKPRELLLAAR
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
IAGLLHDIGHGPFSHAFDYYVLSRHDVVGFRVGNHEILSYVLYRFQLRDTVRRAAEGMGL
HHHHHHHHCCCCHHHHHHHHHEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCC
DGELVVSLVDEAMKPPRDNKEYTDLANSGGFAAGLSGEDFYQPHPDMEPHKLVRLVVRDF
CHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHH
LYPADIMDYLIRDSYFTQAPIGSIDVQRLIGETYVVEYHEQLWPAISRKAVDNLVRLLNA
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKLMYKNVYLHPVNKAFDHTLGMVFNRCNALSTMIAEALDAMLREGRLERYRGLTDYTIY
HHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHH
GMLSYWLATGRLHDECSDSQAAEAVKSLLDYRKPLWKWVQRLSIPEDKAGHLARGKKAVY
HHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
EQQLARDFAEHAGIDPEEVLVDIGRVSAYSSSATTITPYVFIADTVGGRVAAPEPKTLDQ
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEECCEEEEEECCCCCCCCCCCHHHHH
FLHEHRVAGEVIVTFYVERTRYRKLRDDSGAMRRLAEAAKRALHDYVPEAPIREMVETS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]