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The map label for this gene is ttdA [C]

Identifier: 124027056

GI number: 124027056

Start: 143645

End: 144529

Strand: Reverse

Name: ttdA [C]

Synonym: Hbut_0159

Alternate gene names: 124027056

Gene position: 144529-143645 (Counterclockwise)

Preceding gene: 124027058

Following gene: 124027055

Centisome position: 8.67

GC content: 56.61

Gene sequence:

>885_bases
TTGCCTGAGCTTGAGGCCCGGCTACGCGAGTTCCTCGTCGAGTTGATAAGGGTTGCCGAGACCCGGCTGCCGCTCGACGT
CTACAACGCGCTTAAGAAAGCATTGGAGGTTGAGGATAACCCTATAGCGAAGCAGCACCTGGAGGCCATTCTGAGGAACT
CCGAGCTAGCAGCAAAGCTTGGTAAGCCTATATGCCAGGATACCGGTACGCCGGTGTTCTACATAAGGCTTGGTGAGGAG
TTCCCCCTCCGGGCGAAGATATACGAGGTAGCTACTGAAGCTGTGAGAGAGGCGACAAGGCTCATACCATTGAGACCCAA
TGCTGTCAACCCTATACGCGGTGGAAACACGGGCGATAATACTGGCAGGCACATACCGTGGTTCGACGTAGAGATTGTGC
CGGGTGACCGGCTAGAAGTCACGTTTGTAGCTAAGGGCGGTGGCAGCGAGGCGCCCTCAACGCTTAACATGGCACTGCCG
ATAAGGGGGATCCGCAACGTCTGGGAGACAGTACTAAAGGCCGTTGTCTCTGCCGGCCCTAAACCATGCCCACCCGTAGT
CGTCGGCGTTGGCATCGCAGCGCTGGGCGAACAAGCACTGGCAATTGCCAGGAAGGCAGCCCTCCTACGCCCTCTCGGCG
AGAGGCATCCCGAGCCGGAAATAGCTGAGCTAGAGGAGAAGCTCCTCGATGCAATCAACAGTCTGGGTATAGGCGTACAC
GGCTTCGGCGGCAAGATCACTGCGCTAGATGTACACATAGACTATGCGCACCGACACCCAGCAACCTATGCTGTAGGCGT
CGTGTTCAACTGCTGGGCCATAAGGAGGGCAACAGGCTACATAACACCCGATGGCAGGTGGGAGATAACATCAAAACACA
TCTAG

Upstream 100 bases:

>100_bases
GTCCTTGACTGGGTTCTGACCAGCACTGACTAGCATATTTTACACACCGTAAATAGTATTGAAAGTACGGCTGCAGAGAA
ACAAAACGGGTTGATGACAG

Downstream 100 bases:

>100_bases
ATCCATGCAAAGGGGTGAACCCCATGACCAACGTGTATAGGCTCCGGACTCCCCTCTCCGAGGAGGATGTACGCAAGCTA
CGCGTAGGGGACATCGTATA

Product: L(+)-tartrate dehydratase class I, alpha subunit

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MPELEARLREFLVELIRVAETRLPLDVYNALKKALEVEDNPIAKQHLEAILRNSELAAKLGKPICQDTGTPVFYIRLGEE
FPLRAKIYEVATEAVREATRLIPLRPNAVNPIRGGNTGDNTGRHIPWFDVEIVPGDRLEVTFVAKGGGSEAPSTLNMALP
IRGIRNVWETVLKAVVSAGPKPCPPVVVGVGIAALGEQALAIARKAALLRPLGERHPEPEIAELEEKLLDAINSLGIGVH
GFGGKITALDVHIDYAHRHPATYAVGVVFNCWAIRRATGYITPDGRWEITSKHI

Sequences:

>Translated_294_residues
MPELEARLREFLVELIRVAETRLPLDVYNALKKALEVEDNPIAKQHLEAILRNSELAAKLGKPICQDTGTPVFYIRLGEE
FPLRAKIYEVATEAVREATRLIPLRPNAVNPIRGGNTGDNTGRHIPWFDVEIVPGDRLEVTFVAKGGGSEAPSTLNMALP
IRGIRNVWETVLKAVVSAGPKPCPPVVVGVGIAALGEQALAIARKAALLRPLGERHPEPEIAELEEKLLDAINSLGIGVH
GFGGKITALDVHIDYAHRHPATYAVGVVFNCWAIRRATGYITPDGRWEITSKHI
>Mature_293_residues
PELEARLREFLVELIRVAETRLPLDVYNALKKALEVEDNPIAKQHLEAILRNSELAAKLGKPICQDTGTPVFYIRLGEEF
PLRAKIYEVATEAVREATRLIPLRPNAVNPIRGGNTGDNTGRHIPWFDVEIVPGDRLEVTFVAKGGGSEAPSTLNMALPI
RGIRNVWETVLKAVVSAGPKPCPPVVVGVGIAALGEQALAIARKAALLRPLGERHPEPEIAELEEKLLDAINSLGIGVHG
FGGKITALDVHIDYAHRHPATYAVGVVFNCWAIRRATGYITPDGRWEITSKHI

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=283, Percent_Identity=38.5159010600707, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1790564, Length=252, Percent_Identity=30.5555555555556, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787897, Length=256, Percent_Identity=29.6875, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 32115; Mature: 31983

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPELEARLREFLVELIRVAETRLPLDVYNALKKALEVEDNPIAKQHLEAILRNSELAAKL
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHH
GKPICQDTGTPVFYIRLGEEFPLRAKIYEVATEAVREATRLIPLRPNAVNPIRGGNTGDN
CCCHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCC
TGRHIPWFDVEIVPGDRLEVTFVAKGGGSEAPSTLNMALPIRGIRNVWETVLKAVVSAGP
CCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCC
KPCPPVVVGVGIAALGEQALAIARKAALLRPLGERHPEPEIAELEEKLLDAINSLGIGVH
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEE
GFGGKITALDVHIDYAHRHPATYAVGVVFNCWAIRRATGYITPDGRWEITSKHI
CCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCEECCCCCEEECCCCC
>Mature Secondary Structure 
PELEARLREFLVELIRVAETRLPLDVYNALKKALEVEDNPIAKQHLEAILRNSELAAKL
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHH
GKPICQDTGTPVFYIRLGEEFPLRAKIYEVATEAVREATRLIPLRPNAVNPIRGGNTGDN
CCCHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCC
TGRHIPWFDVEIVPGDRLEVTFVAKGGGSEAPSTLNMALPIRGIRNVWETVLKAVVSAGP
CCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCC
KPCPPVVVGVGIAALGEQALAIARKAALLRPLGERHPEPEIAELEEKLLDAINSLGIGVH
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEE
GFGGKITALDVHIDYAHRHPATYAVGVVFNCWAIRRATGYITPDGRWEITSKHI
CCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCEECCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]