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The map label for this gene is rmlA2 [C]

Identifier: 124027047

GI number: 124027047

Start: 134999

End: 135748

Strand: Direct

Name: rmlA2 [C]

Synonym: Hbut_0150

Alternate gene names: 124027047

Gene position: 134999-135748 (Clockwise)

Preceding gene: 124027046

Following gene: 124027048

Centisome position: 8.1

GC content: 57.6

Gene sequence:

>750_bases
ATGCTGGCTCCGAGGCTGGCTGTACTGCTGGCAGCAGGTCTAGGTACGAGGCTTGGTGGTAAGCCCAAGCCGCTACTACG
GGTTGCTGGTAGGCCGCTGGCATGGTATCCGCTTAGCGTACTACACCTAGCGGGGGCAAGGGAGGCCTGTATAGTTACGA
GGAGCGAGATCGCTGACGAGCTGAGGGGGCTTGCATCCTCAATATATGGTGGTGGCAGCGTCACCGTCGTCGTTAACCCT
GAGCCCGAGAGGGAGAACGGATATAGCCTCCTACTAGCAGCAACGGAGTGCCCGTTATTGGTCAGCGAGCCAGCCTACGT
AAGTATGACTGACCACATATACTCGCCGCTGATACCGGTAAGGGCTGGCTACAGCGTACAGACCGGCTACTATATGATAG
CTGGCGACTCTGAGCCCTGCTGCATAGACATCGACGAGGCGACGTTTGTGAAGGCAGTACTTCCACGGGGCTACGATGTT
GGTAAGGGGATAGCCTGGTGGACCCATGTTGACACGGGCGTTCACGTCTATGCGCTCGACTCTTCTGAGCTACAAGCAGT
TGCAGCGGGCGAGTACACTGTGAAGCTTAACACTATAACTTCGAGGCTTGCACAGCGGGGCAGGCTACTCGTAGCAGACG
TCTCGTGCCTCCCCTGGACTGAGATAGATACGCCGAGGGACCTGGAGGAGGCTGAGAGGGGTCAGCGTAGGTGGGTGATA
AGGCATGTCGAAGAGTGGCTCCGCAGTTAG

Upstream 100 bases:

>100_bases
GACCCTCTTGCTCCGTCTTGAGACGCTCGTTGGGTTCGAGTTCAAGTGTAATAGTTGCTCTTCCCTATTGATCTCACTGC
CTTAGGCATGGGGGTGGTTG

Downstream 100 bases:

>100_bases
CTTTGCCAAGCCAACGGACGGCATCATATCGAGAACCATTAACCGGAAGATATCAGCGAGGATAACAATGTGGCTCGCAT
CGTGGAGGAGACCACCGAGC

Product: sugar nucleotidyltransferase

Products: dTDPglucose; Diphosphate [C]

Alternate protein names: Glucose-1-Phosphate Thymidylyltransferase; Glucose-1-Phosphate Thymidylyltransferase Related Protein; Sugar Nucleotidyltransferase; CTPInositol-1-Phosphate Cytidylyltransferase

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MLAPRLAVLLAAGLGTRLGGKPKPLLRVAGRPLAWYPLSVLHLAGAREACIVTRSEIADELRGLASSIYGGGSVTVVVNP
EPERENGYSLLLAATECPLLVSEPAYVSMTDHIYSPLIPVRAGYSVQTGYYMIAGDSEPCCIDIDEATFVKAVLPRGYDV
GKGIAWWTHVDTGVHVYALDSSELQAVAAGEYTVKLNTITSRLAQRGRLLVADVSCLPWTEIDTPRDLEEAERGQRRWVI
RHVEEWLRS

Sequences:

>Translated_249_residues
MLAPRLAVLLAAGLGTRLGGKPKPLLRVAGRPLAWYPLSVLHLAGAREACIVTRSEIADELRGLASSIYGGGSVTVVVNP
EPERENGYSLLLAATECPLLVSEPAYVSMTDHIYSPLIPVRAGYSVQTGYYMIAGDSEPCCIDIDEATFVKAVLPRGYDV
GKGIAWWTHVDTGVHVYALDSSELQAVAAGEYTVKLNTITSRLAQRGRLLVADVSCLPWTEIDTPRDLEEAERGQRRWVI
RHVEEWLRS
>Mature_249_residues
MLAPRLAVLLAAGLGTRLGGKPKPLLRVAGRPLAWYPLSVLHLAGAREACIVTRSEIADELRGLASSIYGGGSVTVVVNP
EPERENGYSLLLAATECPLLVSEPAYVSMTDHIYSPLIPVRAGYSVQTGYYMIAGDSEPCCIDIDEATFVKAVLPRGYDV
GKGIAWWTHVDTGVHVYALDSSELQAVAAGEYTVKLNTITSRLAQRGRLLVADVSCLPWTEIDTPRDLEEAERGQRRWVI
RHVEEWLRS

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1213

COG function: function code M; Predicted sugar nucleotidyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.24 [C]

Molecular weight: Translated: 27169; Mature: 27169

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAPRLAVLLAAGLGTRLGGKPKPLLRVAGRPLAWYPLSVLHLAGAREACIVTRSEIADE
CCCHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEECHHHHHHHCCCCCEEEEEHHHHHHH
LRGLASSIYGGGSVTVVVNPEPERENGYSLLLAATECPLLVSEPAYVSMTDHIYSPLIPV
HHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEECCCCEEECCCCEEEEHHHHHCCCCCC
RAGYSVQTGYYMIAGDSEPCCIDIDEATFVKAVLPRGYDVGKGIAWWTHVDTGVHVYALD
CCCCEEECCEEEEECCCCCCEEECCCHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEEEC
SSELQAVAAGEYTVKLNTITSRLAQRGRLLVADVSCLPWTEIDTPRDLEEAERGQRRWVI
CCCEEEEECCEEEEEEHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
RHVEEWLRS
HHHHHHHCC
>Mature Secondary Structure
MLAPRLAVLLAAGLGTRLGGKPKPLLRVAGRPLAWYPLSVLHLAGAREACIVTRSEIADE
CCCHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEECHHHHHHHCCCCCEEEEEHHHHHHH
LRGLASSIYGGGSVTVVVNPEPERENGYSLLLAATECPLLVSEPAYVSMTDHIYSPLIPV
HHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEECCCCEEECCCCEEEEHHHHHCCCCCC
RAGYSVQTGYYMIAGDSEPCCIDIDEATFVKAVLPRGYDVGKGIAWWTHVDTGVHVYALD
CCCCEEECCEEEEECCCCCCEEECCCHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEEEC
SSELQAVAAGEYTVKLNTITSRLAQRGRLLVADVSCLPWTEIDTPRDLEEAERGQRRWVI
CCCEEEEECCEEEEEEHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
RHVEEWLRS
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTTP; D-Glucose 1-phosphate; H+ [C]

Specific reaction: dTTP + D-Glucose 1-phosphate + H+ --> dTDPglucose + Diphosphate [C]

General reaction: Nucleotidyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA