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The map label for this gene is nrdD [C]

Identifier: 124027037

GI number: 124027037

Start: 120853

End: 122763

Strand: Reverse

Name: nrdD [C]

Synonym: Hbut_0138

Alternate gene names: 124027037

Gene position: 122763-120853 (Counterclockwise)

Preceding gene: 124027041

Following gene: 124027036

Centisome position: 7.36

GC content: 61.12

Gene sequence:

>1911_bases
TTGAAAAGTATAGGAGAGCGAGAGGGCCTGGTTAGTGTCGCGGAGTACCTGGAGGCTTCAGTGTTTGACGTGTTTGAGAA
TGCTAACCGGTATCCTGGCCCTAGCGGGCTCCTAACCTATGTTGCTGAGAAGGCTCTCCGGCCGGTTGTACGGAGTGTGC
TTCCGGAGCCCCTGGCCAGAGCTCATCTTGACGGTAGGGTTTACGTGCACAAGCTGCCATACGCGCTCTTCATACCGTAC
TGCAGCGGTCATAGCGTGGAGCGGCTGCTGCGCAGGGGGCTGAAGACCCCTACGATAACGGCCCGGCCGGCCCGGCACTT
TGACACCTTTGTGGACCATGTGACGAACTACCTGATAGCTATGCAGCACTACTTCAGTGGAGCCCAGGCTTTCGGCGCTG
TGGAGCTCTACGCGGGCCCCTTCATAAGACGCGACAGGCTCGGCTACCGGGAGATACGGCAGGGCGTGCAGAGGCTCATC
TTCAACCTCAACTTCCCGAGCAGGGTTGGCATGCAGACACCATTCACTAACTTTACAGTGGTCCTGGATGCCGCGGAGAC
GAAGCTTGAGAGGGACGACGCCATCTATGCCGGCGAGCCCGTCGGCAAGCTGGGCGAGTACCTCGACGAGGCACGGTTGT
TTGTGCGGGCCCTCTACGAGGTACACATGGAGGGCGATGTTGCCGGCCGACCCTTCACATTCCCCATCCCAACCATTATG
ACTACCAGCAAGCTGCTCTACGACGACCCGGAGATCTTCGATGCCGTCTTCGGCGCTGCAGCCAGGCGGGGGACCGGGTA
CTGGCTAAACACCCGGGTCGTAGACCCGAACGCCAGCTTTGCGATGTGCTGCAGGATAAACATTGACATGAATGAGCTTC
GGCACGCCCTGCGCGTCGGCGGCAAGAGTATGCGTATACGCGACATCCGGAGGGAGCTGGAGCAGGCCAGGGAGGAGTAC
ATACGGAGCCTCGAGAAGCAGCATATGGGCGGCCTCTGGGCAATGCCCGACATTACTGGCAGCAAGGTCGTCATCACGGT
TAACCTGCCCAGGATAGCTCTTGAGGCACGCCGCGACGACGAGGCGTTTGTCGAGAAGCTCGATGAGACCCTGGCGCTTG
TAAGGAGTGGCCTTGAGTGGTTCGCCAGGCGCTACGAGAGGCTCGCCAAGGCCTACCCTGAGTTCTACAGTATGGTTCTC
GAATATGTGCCGGAAGCCCTCCGGTTGATGGGGTCGACGTACTTCCTGCCCGTCGGCGTGATAGGGCTGTCGGAGGCTGC
TGCGATAATGGCTGGCGACCCGAAGGCCTGGACTGAGGGCAGCAGGAGCCAGTGGTTCAGGATGGCCGAGTGGATGAAGA
AGACCGTGGAGCACATCGTGTCGAGGACTAGGGAGTGGAGCAAGAAGACCGGCATACCGTTCAACGTGGAGGAGGTGCCA
GGCGAGAGCGCCGCGGCACGGCTCGCAGAGAGGGACGTCCAGCTCTTCCCGGAGCTACGCGAGTACCTGCCAGACCCCGA
GGAGCCCATCTACAGCACCAGCATAGCCCCCTACTACGCGCCGATGGAGCTATGGGAGCGGGTCGAGGTCGAGGAGCGGG
TGCAGCCAGTCTTCACCGGCGGCGTGATAATGCACATCTTCCTCGGCGAGGAGCCCGACCCAGAGGCCCTCGCAAGCCTC
ACGAGGAAGCTGGCCGCGAACACGAGCCTCGTCTACTGGAGCTACACTCCGGCACTAAGCGTCTGCCCACGCTGCGGCTG
GAGCAGCGTAGGCATCCGCACCACATGCCCCAGGTGTGGAGGCGAGACAGAGATATGGAGTAGGATTGTTGGCTACTACC
GCCCGCTACGGAACTGGAACCCCGCAAGGAGGAGGGAGTTCTGGCTACGCCACCACTACAACAGGCTCTAG

Upstream 100 bases:

>100_bases
GGGTGTTACTCCTGCATGCGGTGTTCCAGCCCTCTCACGACTGTTCTACTCTAACTATGCGGGTAGGGCCTTATACCAGC
GGGGTTCGCTGTGGAGACCC

Downstream 100 bases:

>100_bases
ACGTTGCAAACAGCCAGCCACGGAGAGGCATAGAATGCCTTGCCGCTCGTGGCTTTTGTCGGTGTACACGGCTCCGGCAA
GACCTCCACAGCAAGGCTCC

Product: anaerobic ribonucleoside triphosphate reductase

Products: ribonucleoside triphosphate; thioredoxin

Alternate protein names: NA

Number of amino acids: Translated: 636; Mature: 636

Protein sequence:

>636_residues
MKSIGEREGLVSVAEYLEASVFDVFENANRYPGPSGLLTYVAEKALRPVVRSVLPEPLARAHLDGRVYVHKLPYALFIPY
CSGHSVERLLRRGLKTPTITARPARHFDTFVDHVTNYLIAMQHYFSGAQAFGAVELYAGPFIRRDRLGYREIRQGVQRLI
FNLNFPSRVGMQTPFTNFTVVLDAAETKLERDDAIYAGEPVGKLGEYLDEARLFVRALYEVHMEGDVAGRPFTFPIPTIM
TTSKLLYDDPEIFDAVFGAAARRGTGYWLNTRVVDPNASFAMCCRINIDMNELRHALRVGGKSMRIRDIRRELEQAREEY
IRSLEKQHMGGLWAMPDITGSKVVITVNLPRIALEARRDDEAFVEKLDETLALVRSGLEWFARRYERLAKAYPEFYSMVL
EYVPEALRLMGSTYFLPVGVIGLSEAAAIMAGDPKAWTEGSRSQWFRMAEWMKKTVEHIVSRTREWSKKTGIPFNVEEVP
GESAAARLAERDVQLFPELREYLPDPEEPIYSTSIAPYYAPMELWERVEVEERVQPVFTGGVIMHIFLGEEPDPEALASL
TRKLAANTSLVYWSYTPALSVCPRCGWSSVGIRTTCPRCGGETEIWSRIVGYYRPLRNWNPARRREFWLRHHYNRL

Sequences:

>Translated_636_residues
MKSIGEREGLVSVAEYLEASVFDVFENANRYPGPSGLLTYVAEKALRPVVRSVLPEPLARAHLDGRVYVHKLPYALFIPY
CSGHSVERLLRRGLKTPTITARPARHFDTFVDHVTNYLIAMQHYFSGAQAFGAVELYAGPFIRRDRLGYREIRQGVQRLI
FNLNFPSRVGMQTPFTNFTVVLDAAETKLERDDAIYAGEPVGKLGEYLDEARLFVRALYEVHMEGDVAGRPFTFPIPTIM
TTSKLLYDDPEIFDAVFGAAARRGTGYWLNTRVVDPNASFAMCCRINIDMNELRHALRVGGKSMRIRDIRRELEQAREEY
IRSLEKQHMGGLWAMPDITGSKVVITVNLPRIALEARRDDEAFVEKLDETLALVRSGLEWFARRYERLAKAYPEFYSMVL
EYVPEALRLMGSTYFLPVGVIGLSEAAAIMAGDPKAWTEGSRSQWFRMAEWMKKTVEHIVSRTREWSKKTGIPFNVEEVP
GESAAARLAERDVQLFPELREYLPDPEEPIYSTSIAPYYAPMELWERVEVEERVQPVFTGGVIMHIFLGEEPDPEALASL
TRKLAANTSLVYWSYTPALSVCPRCGWSSVGIRTTCPRCGGETEIWSRIVGYYRPLRNWNPARRREFWLRHHYNRL
>Mature_636_residues
MKSIGEREGLVSVAEYLEASVFDVFENANRYPGPSGLLTYVAEKALRPVVRSVLPEPLARAHLDGRVYVHKLPYALFIPY
CSGHSVERLLRRGLKTPTITARPARHFDTFVDHVTNYLIAMQHYFSGAQAFGAVELYAGPFIRRDRLGYREIRQGVQRLI
FNLNFPSRVGMQTPFTNFTVVLDAAETKLERDDAIYAGEPVGKLGEYLDEARLFVRALYEVHMEGDVAGRPFTFPIPTIM
TTSKLLYDDPEIFDAVFGAAARRGTGYWLNTRVVDPNASFAMCCRINIDMNELRHALRVGGKSMRIRDIRRELEQAREEY
IRSLEKQHMGGLWAMPDITGSKVVITVNLPRIALEARRDDEAFVEKLDETLALVRSGLEWFARRYERLAKAYPEFYSMVL
EYVPEALRLMGSTYFLPVGVIGLSEAAAIMAGDPKAWTEGSRSQWFRMAEWMKKTVEHIVSRTREWSKKTGIPFNVEEVP
GESAAARLAERDVQLFPELREYLPDPEEPIYSTSIAPYYAPMELWERVEVEERVQPVFTGGVIMHIFLGEEPDPEALASL
TRKLAANTSLVYWSYTPALSVCPRCGWSSVGIRTTCPRCGGETEIWSRIVGYYRPLRNWNPARRREFWLRHHYNRL

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DOD-type homing endonuclease domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003586
- InterPro:   IPR003587
- InterPro:   IPR007869
- InterPro:   IPR006142
- InterPro:   IPR004042
- InterPro:   IPR006141
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF05204 Hom_end [H]

EC number: 1.17.4.2

Molecular weight: Translated: 72736; Mature: 72736

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSIGEREGLVSVAEYLEASVFDVFENANRYPGPSGLLTYVAEKALRPVVRSVLPEPLAR
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
AHLDGRVYVHKLPYALFIPYCSGHSVERLLRRGLKTPTITARPARHFDTFVDHVTNYLIA
HCCCCEEEEEECCCEEEEECCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
MQHYFSGAQAFGAVELYAGPFIRRDRLGYREIRQGVQRLIFNLNFPSRVGMQTPFTNFTV
HHHHHCCHHHHCEEEHHCCCCHHHHCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCCEEE
VLDAAETKLERDDAIYAGEPVGKLGEYLDEARLFVRALYEVHMEGDVAGRPFTFPIPTIM
EEECHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
TTSKLLYDDPEIFDAVFGAAARRGTGYWLNTRVVDPNASFAMCCRINIDMNELRHALRVG
HHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEEECCCHHHHHHHHHHC
GKSMRIRDIRRELEQAREEYIRSLEKQHMGGLWAMPDITGSKVVITVNLPRIALEARRDD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEEEECCHHHHHCCCCH
EAFVEKLDETLALVRSGLEWFARRYERLAKAYPEFYSMVLEYVPEALRLMGSTYFLPVGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IGLSEAAAIMAGDPKAWTEGSRSQWFRMAEWMKKTVEHIVSRTREWSKKTGIPFNVEEVP
HHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCC
GESAAARLAERDVQLFPELREYLPDPEEPIYSTSIAPYYAPMELWERVEVEERVQPVFTG
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCC
GVIMHIFLGEEPDPEALASLTRKLAANTSLVYWSYTPALSVCPRCGWSSVGIRTTCPRCG
CEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCCCCCCCCCCCCCCC
GETEIWSRIVGYYRPLRNWNPARRREFWLRHHYNRL
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKSIGEREGLVSVAEYLEASVFDVFENANRYPGPSGLLTYVAEKALRPVVRSVLPEPLAR
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
AHLDGRVYVHKLPYALFIPYCSGHSVERLLRRGLKTPTITARPARHFDTFVDHVTNYLIA
HCCCCEEEEEECCCEEEEECCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
MQHYFSGAQAFGAVELYAGPFIRRDRLGYREIRQGVQRLIFNLNFPSRVGMQTPFTNFTV
HHHHHCCHHHHCEEEHHCCCCHHHHCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCCEEE
VLDAAETKLERDDAIYAGEPVGKLGEYLDEARLFVRALYEVHMEGDVAGRPFTFPIPTIM
EEECHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
TTSKLLYDDPEIFDAVFGAAARRGTGYWLNTRVVDPNASFAMCCRINIDMNELRHALRVG
HHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEEECCCHHHHHHHHHHC
GKSMRIRDIRRELEQAREEYIRSLEKQHMGGLWAMPDITGSKVVITVNLPRIALEARRDD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEEEECCHHHHHCCCCH
EAFVEKLDETLALVRSGLEWFARRYERLAKAYPEFYSMVLEYVPEALRLMGSTYFLPVGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IGLSEAAAIMAGDPKAWTEGSRSQWFRMAEWMKKTVEHIVSRTREWSKKTGIPFNVEEVP
HHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCC
GESAAARLAERDVQLFPELREYLPDPEEPIYSTSIAPYYAPMELWERVEVEERVQPVFTG
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCC
GVIMHIFLGEEPDPEALASLTRKLAANTSLVYWSYTPALSVCPRCGWSSVGIRTTCPRCG
CEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCCCCCCCCCCCCCCC
GETEIWSRIVGYYRPLRNWNPARRREFWLRHHYNRL
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Ca2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2'-deoxyribonucleoside triphosphate; thioredoxin disulfide; H2O

Specific reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]