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The map label for this gene is rio2 [H]

Identifier: 124026974

GI number: 124026974

Start: 63555

End: 64454

Strand: Direct

Name: rio2 [H]

Synonym: Hbut_0072

Alternate gene names: 124026974

Gene position: 63555-64454 (Clockwise)

Preceding gene: 124026971

Following gene: 124026975

Centisome position: 3.81

GC content: 48.78

Gene sequence:

>900_bases
ATGGTGCTGCTAGCATTGACATATAAGAAGCTCGTGCCAAGAGACTTCAAAGTATTGCAAGTAATCGAGAGGGAGATGCC
ACGCTATGAGTATGTTCCGGTAGAACTTATAGAGCGAAGGCTTAGAATGCCTTCGAGCCATGTGGCTATGAGCTTACAGA
AGCTCAACCAGCTAAAACTGGTGAGAAGGAGGCTAGGCGAGTATGTGGGCTACCGCCTAACCTACATGGGGCTGGACATG
CTAGCCATACACTCGCTTGTAGAGCGCGGTATCCTACATGCATTGGGGGACAAACTCGGTGTTGGCAAAGAGAGCGATGT
ATACTCTGGGCTAACACCTACCGGGGAGAGGGTCATAGTAAAATTCCATCGTGTGGGAAGGACAAGCTTTCAGCGCGTTG
TAAGAGTTAGAACTTACGCTGCTGATAGGCCATATGCAACCTGGCTACAGATAGCCAAGGTTGCTGGGCAGCGGGAGTAC
CGGGTATTAGAGGAACTCTATCGCGAGGGCGCGCTTGTACCGAAGCCGCTGGGATATAGCAGACATGCAGTTGTAACAGA
ATATCTTGAGGGTGTTGAGCTATACTTGTACAAGGACCCTATAGACCCGGAGTCCATGCTGCAGAGGATACTTGAGACTC
TACGTAAGGCTTACCTAGACGTAGGCATAGTACATGGAGACCTAAGTGAGTATAATGTGCTTGTTGTGATAGAGGATGAG
GAGGAGAAGCCGTATATTATAGACTGGCCACAATACGTTGAGCGAGAACATCCATCAGCAGAGCAGCTACTTCGCCGCGA
TGTGGAGTACATCGTAAGGTTCTTCCGTAAAAAGTATGGCGTAGAGGTTGATGCTGAGAAAGCACTTAAATACGTTAAGG
GTGAGGTTGAAACTGTCTAG

Upstream 100 bases:

>100_bases
AACCCCTATAAGCTTTCCCCACAACATTATACATGTTAAATAGTGTTAGTCGTCTAGATTATAGGCTTGTGGACCACAGC
GGGGTAAGGGGGTTCTAGGG

Downstream 100 bases:

>100_bases
CGTGTCTCTGGTTTACAGTCCTATCATTAGGGAACCATACTAGTCTTGACTTATAAAATGAAACAAATATTTATGCTACT
GGTTTCCTTGAAGCGTAGAC

Product: RIO-like serine/threonine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MVLLALTYKKLVPRDFKVLQVIEREMPRYEYVPVELIERRLRMPSSHVAMSLQKLNQLKLVRRRLGEYVGYRLTYMGLDM
LAIHSLVERGILHALGDKLGVGKESDVYSGLTPTGERVIVKFHRVGRTSFQRVVRVRTYAADRPYATWLQIAKVAGQREY
RVLEELYREGALVPKPLGYSRHAVVTEYLEGVELYLYKDPIDPESMLQRILETLRKAYLDVGIVHGDLSEYNVLVVIEDE
EEKPYIIDWPQYVEREHPSAEQLLRRDVEYIVRFFRKKYGVEVDAEKALKYVKGEVETV

Sequences:

>Translated_299_residues
MVLLALTYKKLVPRDFKVLQVIEREMPRYEYVPVELIERRLRMPSSHVAMSLQKLNQLKLVRRRLGEYVGYRLTYMGLDM
LAIHSLVERGILHALGDKLGVGKESDVYSGLTPTGERVIVKFHRVGRTSFQRVVRVRTYAADRPYATWLQIAKVAGQREY
RVLEELYREGALVPKPLGYSRHAVVTEYLEGVELYLYKDPIDPESMLQRILETLRKAYLDVGIVHGDLSEYNVLVVIEDE
EEKPYIIDWPQYVEREHPSAEQLLRRDVEYIVRFFRKKYGVEVDAEKALKYVKGEVETV
>Mature_299_residues
MVLLALTYKKLVPRDFKVLQVIEREMPRYEYVPVELIERRLRMPSSHVAMSLQKLNQLKLVRRRLGEYVGYRLTYMGLDM
LAIHSLVERGILHALGDKLGVGKESDVYSGLTPTGERVIVKFHRVGRTSFQRVVRVRTYAADRPYATWLQIAKVAGQREY
RVLEELYREGALVPKPLGYSRHAVVTEYLEGVELYLYKDPIDPESMLQRILETLRKAYLDVGIVHGDLSEYNVLVVIEDE
EEKPYIIDWPQYVEREHPSAEQLLRRDVEYIVRFFRKKYGVEVDAEKALKYVKGEVETV

Specific function: Unknown

COG id: COG0478

COG function: function code T; RIO-like serine/threonine protein kinase fused to N-terminal HTH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI229331971, Length=282, Percent_Identity=34.7517730496454, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI229331967, Length=282, Percent_Identity=34.7517730496454, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI23510356, Length=204, Percent_Identity=27.4509803921569, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI32564178, Length=268, Percent_Identity=35.0746268656716, Blast_Score=167, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI115532073, Length=210, Percent_Identity=30, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17556977, Length=201, Percent_Identity=22.3880597014925, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6324122, Length=291, Percent_Identity=34.7079037800687, Blast_Score=169, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6324693, Length=275, Percent_Identity=25.0909090909091, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24649986, Length=273, Percent_Identity=34.0659340659341, Blast_Score=171, Evalue=5e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR018934
- InterPro:   IPR015285
- InterPro:   IPR000687
- InterPro:   IPR018935 [H]

Pfam domain/function: PF01163 RIO1; PF09202 Rio2_N [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 34962; Mature: 34962

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS00109 PROTEIN_KINASE_TYR ; PS01245 RIO1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLLALTYKKLVPRDFKVLQVIEREMPRYEYVPVELIERRLRMPSSHVAMSLQKLNQLKL
CEEEEEHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
VRRRLGEYVGYRLTYMGLDMLAIHSLVERGILHALGDKLGVGKESDVYSGLTPTGERVIV
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
KFHRVGRTSFQRVVRVRTYAADRPYATWLQIAKVAGQREYRVLEELYREGALVPKPLGYS
HHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCC
RHAVVTEYLEGVELYLYKDPIDPESMLQRILETLRKAYLDVGIVHGDLSEYNVLVVIEDE
HHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEECC
EEKPYIIDWPQYVEREHPSAEQLLRRDVEYIVRFFRKKYGVEVDAEKALKYVKGEVETV
CCCCEEECCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MVLLALTYKKLVPRDFKVLQVIEREMPRYEYVPVELIERRLRMPSSHVAMSLQKLNQLKL
CEEEEEHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
VRRRLGEYVGYRLTYMGLDMLAIHSLVERGILHALGDKLGVGKESDVYSGLTPTGERVIV
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
KFHRVGRTSFQRVVRVRTYAADRPYATWLQIAKVAGQREYRVLEELYREGALVPKPLGYS
HHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCC
RHAVVTEYLEGVELYLYKDPIDPESMLQRILETLRKAYLDVGIVHGDLSEYNVLVVIEDE
HHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEECC
EEKPYIIDWPQYVEREHPSAEQLLRRDVEYIVRFFRKKYGVEVDAEKALKYVKGEVETV
CCCCEEECCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]