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The map label for this gene is 124026966

Identifier: 124026966

GI number: 124026966

Start: 51739

End: 53574

Strand: Direct

Name: 124026966

Synonym: Hbut_0064

Alternate gene names: NA

Gene position: 51739-53574 (Clockwise)

Preceding gene: 124026965

Following gene: 124026970

Centisome position: 3.1

GC content: 53.43

Gene sequence:

>1836_bases
GTGGCGAGGTTTCCCTATGCTAAGCCGCGGAGGGGCCAGCTCGAAGCTGCTAGGGCTATAGTCTCTACCGTGCGTGAGGG
TGGCGTCTTCGTACTCAGTGCGCCTACAGGCTTTGGCAAGACGTCAACCATCATATATGGATTGCTTGAGGCTGGTGTAG
AGCGCATCCTCTACGTTGTAAGGACTAGGAATGAGATAGCCCCCGTGTTGAGGGAACTTCGGCGCTTCGGTGTTGAGCGG
TACTCGTTCCTCTACAGTGCTAGGCGCATGTGCCCACTCCTTGCAGGAGAGCAGCTAGCAACCGAGGACTTCTGGGAGAC
ATGCAGGCTCCTAAGGCTGCGAGGCGAGTGTATGTACCATGAGAATCTTGTCGAGGTTAGTGAGGAGACCGTAGAAGCAA
TAGTAACCAGCATAGGCGAGAGCAAGCCGTCAGAAGTTGTAGCAGCTCTAAGGAACGCCGGGCTATGCCCCTTCTTCTCG
CTCCGCCTAGCTTCAACCCGTGCAGCGATAACGGTTGCTACTTACCCTTACCTCTTCCGCGAAGACATATTCACAAGCGT
CTTCGAGCCACTAACCTATGGCGACTTCGTCGTAGTCGTTGACGAGGCCCACTCACTGCTCACTATACAGTCCATGCTAG
AGGCAAGGCTCACGCTTGAAACACTTCGGGCGGCACTGGACGAGATAGAGGAGTACGGCCTGCCAGGAGAGCTGACAGTA
GCGCTCAAAAAGCTCCTCGACATGCTGTCGTCTAGTACAGCTCCGAGAATGGCTATGAAGAGGCTTGAGAAGAACAAGAT
CAGAGACATACTTGCAGAGCCAGACCTATGGCTCGATGCGGCGCAGGAGGTAAGAGCTGCAAAGCTACGTGAACGCCTCG
AGCAAGGTGCTCCAGTTAAGCTCAGTGTAGCGCTAACAAGGGTAGCCAACTTCGCAGCCATGGTGTTCCGAGAGGATACA
GGGGTCTACCTCCGCAAGGAGAATGGTCGCCGTGTCCTCATAGCGCTACCGGTGGAGCCGTGTAGCGTTACCGAGAAACC
ACTAAACGAGGCCAAGGCCGTAATCCTCTCTAGCGGTACAATGCCCGCGTCAAGTATCCTCCGCGACGTACTCTGCATAA
GGAAGCCAATGAAGGTTTACGAGGTGGAGCTGCTGCACGGCCATATATTCCCACCGGAGAACATCTATACAGTGTTAGCG
CTTGAGATAACCTCGCGCTACACGAGTAGGAGTAGAGAGATGTATGCGCGCTACGCCGAGTACATAGCAGAAACATTTAG
AGCGGTTAGGAACGCAGTGCTCATAGTATATCCAAGTTATGAGTTTATGGAGGCCATACTCTCACACCTCAAGCATCTGT
TGAGCGGGGAGCCAATGGTCGTAGAGGGACGCGACACAAGTATAGAGCAGGTAGAAGAGTATGTACGGAGACACGGCCAC
GTAGCAATACATGCGGTAGCTGGTGGAAAGCTAACAGAGGGCATAGAGATCGTCGAGAACGGCGAGAGCTTAATCAAAAC
AGTATTTGTTGCAGGTGTGCCCTACCCTCAGCCGGATGACTATGTAGCAGATCAATATGAAGTACTGGCAAAACGCATGG
GCACGACTGAGGCCAAGACGTTTCTCTACGACTACACAGCGGCAGTAAAAACAAGACAAGCAGTAGGGAGGGTGCGTCGC
AGCGAGAAGGACCGTGCGCTCATAATCCTCGGTGATGTGAGATTTGCGAGAAGAAGGCTGAGAGAATACCTACGACTACG
AATAGACGCGTATGCAGCCACGCTAGAGGACTACGTGGCGCGTGTACGGGCTGCAGCAGAAAAACTCAAGGTTTAA

Upstream 100 bases:

>100_bases
GGCAAGCAGTCTAGCATAGGTACACCGTTGCTTGTCTACAAGCCTCCCAGACCTTTAGGCTGGAGGGTGTTGGACAGCTG
TAGTAGTGGGAAGGATAGGT

Downstream 100 bases:

>100_bases
AGGGAGACGGCAGCACAATTCACGCCTGGAACCCCGGTCCCCTGCGAGCACAAGGCCCCGAGTCCCGGGGAACAGATGAG
CAGGGGGCGGGTCACTCCCG

Product: XPD/Rad3 related DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 611; Mature: 610

Protein sequence:

>611_residues
MARFPYAKPRRGQLEAARAIVSTVREGGVFVLSAPTGFGKTSTIIYGLLEAGVERILYVVRTRNEIAPVLRELRRFGVER
YSFLYSARRMCPLLAGEQLATEDFWETCRLLRLRGECMYHENLVEVSEETVEAIVTSIGESKPSEVVAALRNAGLCPFFS
LRLASTRAAITVATYPYLFREDIFTSVFEPLTYGDFVVVVDEAHSLLTIQSMLEARLTLETLRAALDEIEEYGLPGELTV
ALKKLLDMLSSSTAPRMAMKRLEKNKIRDILAEPDLWLDAAQEVRAAKLRERLEQGAPVKLSVALTRVANFAAMVFREDT
GVYLRKENGRRVLIALPVEPCSVTEKPLNEAKAVILSSGTMPASSILRDVLCIRKPMKVYEVELLHGHIFPPENIYTVLA
LEITSRYTSRSREMYARYAEYIAETFRAVRNAVLIVYPSYEFMEAILSHLKHLLSGEPMVVEGRDTSIEQVEEYVRRHGH
VAIHAVAGGKLTEGIEIVENGESLIKTVFVAGVPYPQPDDYVADQYEVLAKRMGTTEAKTFLYDYTAAVKTRQAVGRVRR
SEKDRALIILGDVRFARRRLREYLRLRIDAYAATLEDYVARVRAAAEKLKV

Sequences:

>Translated_611_residues
MARFPYAKPRRGQLEAARAIVSTVREGGVFVLSAPTGFGKTSTIIYGLLEAGVERILYVVRTRNEIAPVLRELRRFGVER
YSFLYSARRMCPLLAGEQLATEDFWETCRLLRLRGECMYHENLVEVSEETVEAIVTSIGESKPSEVVAALRNAGLCPFFS
LRLASTRAAITVATYPYLFREDIFTSVFEPLTYGDFVVVVDEAHSLLTIQSMLEARLTLETLRAALDEIEEYGLPGELTV
ALKKLLDMLSSSTAPRMAMKRLEKNKIRDILAEPDLWLDAAQEVRAAKLRERLEQGAPVKLSVALTRVANFAAMVFREDT
GVYLRKENGRRVLIALPVEPCSVTEKPLNEAKAVILSSGTMPASSILRDVLCIRKPMKVYEVELLHGHIFPPENIYTVLA
LEITSRYTSRSREMYARYAEYIAETFRAVRNAVLIVYPSYEFMEAILSHLKHLLSGEPMVVEGRDTSIEQVEEYVRRHGH
VAIHAVAGGKLTEGIEIVENGESLIKTVFVAGVPYPQPDDYVADQYEVLAKRMGTTEAKTFLYDYTAAVKTRQAVGRVRR
SEKDRALIILGDVRFARRRLREYLRLRIDAYAATLEDYVARVRAAAEKLKV
>Mature_610_residues
ARFPYAKPRRGQLEAARAIVSTVREGGVFVLSAPTGFGKTSTIIYGLLEAGVERILYVVRTRNEIAPVLRELRRFGVERY
SFLYSARRMCPLLAGEQLATEDFWETCRLLRLRGECMYHENLVEVSEETVEAIVTSIGESKPSEVVAALRNAGLCPFFSL
RLASTRAAITVATYPYLFREDIFTSVFEPLTYGDFVVVVDEAHSLLTIQSMLEARLTLETLRAALDEIEEYGLPGELTVA
LKKLLDMLSSSTAPRMAMKRLEKNKIRDILAEPDLWLDAAQEVRAAKLRERLEQGAPVKLSVALTRVANFAAMVFREDTG
VYLRKENGRRVLIALPVEPCSVTEKPLNEAKAVILSSGTMPASSILRDVLCIRKPMKVYEVELLHGHIFPPENIYTVLAL
EITSRYTSRSREMYARYAEYIAETFRAVRNAVLIVYPSYEFMEAILSHLKHLLSGEPMVVEGRDTSIEQVEEYVRRHGHV
AIHAVAGGKLTEGIEIVENGESLIKTVFVAGVPYPQPDDYVADQYEVLAKRMGTTEAKTFLYDYTAAVKTRQAVGRVRRS
EKDRALIILGDVRFARRRLREYLRLRIDAYAATLEDYVARVRAAAEKLKV

Specific function: Unknown

COG id: COG1199

COG function: function code KL; Rad3-related DNA helicases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase ATP-binding domain [H]

Homologues:

Organism=Homo sapiens, GI100913202, Length=282, Percent_Identity=25.531914893617, Blast_Score=74, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6325249, Length=616, Percent_Identity=24.025974025974, Blast_Score=93, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010614
- InterPro:   IPR014013
- InterPro:   IPR006555 [H]

Pfam domain/function: PF06733 DEAD_2 [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 68893; Mature: 68762

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARFPYAKPRRGQLEAARAIVSTVREGGVFVLSAPTGFGKTSTIIYGLLEAGVERILYVV
CCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
RTRNEIAPVLRELRRFGVERYSFLYSARRMCPLLAGEQLATEDFWETCRLLRLRGECMYH
HCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHH
ENLVEVSEETVEAIVTSIGESKPSEVVAALRNAGLCPFFSLRLASTRAAITVATYPYLFR
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEECCHHHHH
EDIFTSVFEPLTYGDFVVVVDEAHSLLTIQSMLEARLTLETLRAALDEIEEYGLPGELTV
HHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ALKKLLDMLSSSTAPRMAMKRLEKNKIRDILAEPDLWLDAAQEVRAAKLRERLEQGAPVK
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
LSVALTRVANFAAMVFREDTGVYLRKENGRRVLIALPVEPCSVTEKPLNEAKAVILSSGT
EHHHHHHHHHHHHHEEECCCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHHEEEEECCC
MPASSILRDVLCIRKPMKVYEVELLHGHIFPPENIYTVLALEITSRYTSRSREMYARYAE
CCHHHHHHHHHHHHCCCHHHEEHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
YIAETFRAVRNAVLIVYPSYEFMEAILSHLKHLLSGEPMVVEGRDTSIEQVEEYVRRHGH
HHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCC
VAIHAVAGGKLTEGIEIVENGESLIKTVFVAGVPYPQPDDYVADQYEVLAKRMGTTEAKT
EEEEEECCCCHHCCHHHHHCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHH
FLYDYTAAVKTRQAVGRVRRSEKDRALIILGDVRFARRRLREYLRLRIDAYAATLEDYVA
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVRAAAEKLKV
HHHHHHHHHCC
>Mature Secondary Structure 
ARFPYAKPRRGQLEAARAIVSTVREGGVFVLSAPTGFGKTSTIIYGLLEAGVERILYVV
CCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
RTRNEIAPVLRELRRFGVERYSFLYSARRMCPLLAGEQLATEDFWETCRLLRLRGECMYH
HCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHH
ENLVEVSEETVEAIVTSIGESKPSEVVAALRNAGLCPFFSLRLASTRAAITVATYPYLFR
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEECCHHHHH
EDIFTSVFEPLTYGDFVVVVDEAHSLLTIQSMLEARLTLETLRAALDEIEEYGLPGELTV
HHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ALKKLLDMLSSSTAPRMAMKRLEKNKIRDILAEPDLWLDAAQEVRAAKLRERLEQGAPVK
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
LSVALTRVANFAAMVFREDTGVYLRKENGRRVLIALPVEPCSVTEKPLNEAKAVILSSGT
EHHHHHHHHHHHHHEEECCCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHHEEEEECCC
MPASSILRDVLCIRKPMKVYEVELLHGHIFPPENIYTVLALEITSRYTSRSREMYARYAE
CCHHHHHHHHHHHHCCCHHHEEHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
YIAETFRAVRNAVLIVYPSYEFMEAILSHLKHLLSGEPMVVEGRDTSIEQVEEYVRRHGH
HHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCC
VAIHAVAGGKLTEGIEIVENGESLIKTVFVAGVPYPQPDDYVADQYEVLAKRMGTTEAKT
EEEEEECCCCHHCCHHHHHCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHH
FLYDYTAAVKTRQAVGRVRRSEKDRALIILGDVRFARRRLREYLRLRIDAYAATLEDYVA
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVRAAAEKLKV
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA