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The map label for this gene is speB [C]

Identifier: 124026954

GI number: 124026954

Start: 41953

End: 42891

Strand: Direct

Name: speB [C]

Synonym: Hbut_0051

Alternate gene names: 124026954

Gene position: 41953-42891 (Clockwise)

Preceding gene: 124026950

Following gene: 124026956

Centisome position: 2.52

GC content: 50.91

Gene sequence:

>939_bases
ATGGGTATAGCTGAACTATATCTCTCAAGGAGCAGCCTCCTCTTTGGCGGCGTTGAGGTGCCGCTAGAGCGGGCTGAGGC
AGTTATTGTTGGTGTACCATTTGACTATACGTCAAGCTACCGGCCTGGCTCGCGCTTTGCCCCCCGTGCGATAAGAGAGG
CAGCTGCAAACATAGAATTCTATTCGCTGAGAGCGAATCTTGACGTGGAAAATATAGGTATAAGCGATCTAGGCGACATA
GCAGTATCATCGCAGCCCCTTGAAACATTGCAGCGTATCGAGCAGGTGACAAGAGAACTGCTCGAGAATATGCAAGATAA
GCTGCTAATAGTGCTCGGTGGTGAACATACAATAACGCTTGGTGTTGCCAAGGCCCTAGCAGCTACAAGGGAGCAACCAC
TATGCCTCATAGTCTTTGATGCCCACCTCGATCTCCGACAGGAGTACATGGGCGAGAAATACTCGCATGCTAGTGTCATG
AGGAGAGTTGTTGAGCAAGTAACCAGCAACATATTCTACATCGGTGCCAGAGCATTTACAAGCGAGGAGTTTTCGTATAT
GCGCAGCCACGGCTTACAAATGGTAACCCCACAGCAAGCCCGGCTCCTAGGGCTAGCTGAGATCGTACGGAGAATCCGTA
ACTGGGCTAAATCCAGTGAGTGCAAAACGCTATACATAAGCTTCGACATAGACGCATACGACCCTGCCTATGCACCCGGC
GCAGCAAATCCCGAACCTGACGGGCTGGAAACTTGGCTTGCACTAGAACTCCTACACCGTATCATAATCGAGGTACCGGC
AACCATTGCAGTCTTTGACTTAGTAGAGGTCTCACCACCCTACGACTGCTCCTGGATAACGAGCATACTAGCAGCAAAAA
CAGTGGTAGAAGCCATAGCCGCAAACCATGTAGCGCGCCGAGCAGCTAGACAGCCTTGA

Upstream 100 bases:

>100_bases
CCCTCACCCAGCAAGAGCCCTTTACACGCGGATATATTACTCGCCCCCGTCTAGTAAAGCCAATGCACGCAACGAGGCTC
CTAGGGGTGCATAGTAGGCC

Downstream 100 bases:

>100_bases
CGAGCTTTCTACCCGGAGGCCTAACCTTGTATACAACCCTATAGCCACAGTAGGGACACTTAATCGTAGGCATATACTCT
AGGTCGAGGGCGCTAAACTC

Product: agmatinase

Products: putrescine; urea

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MGIAELYLSRSSLLFGGVEVPLERAEAVIVGVPFDYTSSYRPGSRFAPRAIREAAANIEFYSLRANLDVENIGISDLGDI
AVSSQPLETLQRIEQVTRELLENMQDKLLIVLGGEHTITLGVAKALAATREQPLCLIVFDAHLDLRQEYMGEKYSHASVM
RRVVEQVTSNIFYIGARAFTSEEFSYMRSHGLQMVTPQQARLLGLAEIVRRIRNWAKSSECKTLYISFDIDAYDPAYAPG
AANPEPDGLETWLALELLHRIIIEVPATIAVFDLVEVSPPYDCSWITSILAAKTVVEAIAANHVARRAARQP

Sequences:

>Translated_312_residues
MGIAELYLSRSSLLFGGVEVPLERAEAVIVGVPFDYTSSYRPGSRFAPRAIREAAANIEFYSLRANLDVENIGISDLGDI
AVSSQPLETLQRIEQVTRELLENMQDKLLIVLGGEHTITLGVAKALAATREQPLCLIVFDAHLDLRQEYMGEKYSHASVM
RRVVEQVTSNIFYIGARAFTSEEFSYMRSHGLQMVTPQQARLLGLAEIVRRIRNWAKSSECKTLYISFDIDAYDPAYAPG
AANPEPDGLETWLALELLHRIIIEVPATIAVFDLVEVSPPYDCSWITSILAAKTVVEAIAANHVARRAARQP
>Mature_311_residues
GIAELYLSRSSLLFGGVEVPLERAEAVIVGVPFDYTSSYRPGSRFAPRAIREAAANIEFYSLRANLDVENIGISDLGDIA
VSSQPLETLQRIEQVTRELLENMQDKLLIVLGGEHTITLGVAKALAATREQPLCLIVFDAHLDLRQEYMGEKYSHASVMR
RVVEQVTSNIFYIGARAFTSEEFSYMRSHGLQMVTPQQARLLGLAEIVRRIRNWAKSSECKTLYISFDIDAYDPAYAPGA
ANPEPDGLETWLALELLHRIIIEVPATIAVFDLVEVSPPYDCSWITSILAAKTVVEAIAANHVARRAARQP

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=291, Percent_Identity=34.020618556701, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI4502215, Length=312, Percent_Identity=24.6794871794872, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1789306, Length=285, Percent_Identity=28.0701754385965, Blast_Score=95, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: 3.5.3.11

Molecular weight: Translated: 34623; Mature: 34492

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIAELYLSRSSLLFGGVEVPLERAEAVIVGVPFDYTSSYRPGSRFAPRAIREAAANIEF
CCHHHHHHHHCHHEECCCCCCHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCEE
YSLRANLDVENIGISDLGDIAVSSQPLETLQRIEQVTRELLENMQDKLLIVLGGEHTITL
EEEEECCCHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEECCCEEEHH
GVAKALAATREQPLCLIVFDAHLDLRQEYMGEKYSHASVMRRVVEQVTSNIFYIGARAFT
HHHHHHHHHCCCCEEEEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEEHHHHH
SEEFSYMRSHGLQMVTPQQARLLGLAEIVRRIRNWAKSSECKTLYISFDIDAYDPAYAPG
HHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCC
AANPEPDGLETWLALELLHRIIIEVPATIAVFDLVEVSPPYDCSWITSILAAKTVVEAIA
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
ANHVARRAARQP
HHHHHHHHCCCC
>Mature Secondary Structure 
GIAELYLSRSSLLFGGVEVPLERAEAVIVGVPFDYTSSYRPGSRFAPRAIREAAANIEF
CHHHHHHHHCHHEECCCCCCHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCEE
YSLRANLDVENIGISDLGDIAVSSQPLETLQRIEQVTRELLENMQDKLLIVLGGEHTITL
EEEEECCCHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEECCCEEEHH
GVAKALAATREQPLCLIVFDAHLDLRQEYMGEKYSHASVMRRVVEQVTSNIFYIGARAFT
HHHHHHHHHCCCCEEEEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEEHHHHH
SEEFSYMRSHGLQMVTPQQARLLGLAEIVRRIRNWAKSSECKTLYISFDIDAYDPAYAPG
HHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCC
AANPEPDGLETWLALELLHRIIIEVPATIAVFDLVEVSPPYDCSWITSILAAKTVVEAIA
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
ANHVARRAARQP
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: agmatine; H2O

Specific reaction: agmatine + H2O = putrescine + urea

General reaction: Amidine hydrolysis [C]

Inhibitor: EDTA; EGTA [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]