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The map label for this gene is ubiX [C]

Identifier: 124026946

GI number: 124026946

Start: 34883

End: 35476

Strand: Direct

Name: ubiX [C]

Synonym: Hbut_0043

Alternate gene names: 124026946

Gene position: 34883-35476 (Clockwise)

Preceding gene: 124026945

Following gene: 124026950

Centisome position: 2.09

GC content: 52.19

Gene sequence:

>594_bases
ATGTTGCTGCGTGGCAGAAGAGTGCTTGTGGCGATAACAGGGGCTAGTGGCGTAATCTATGGTGCTAGGCTCGTAGCGCA
CCTCGCGAAGAGGGGGCTCCTCGAGGCAGTAATCTACACTCCATCAGCGTTAATAGTTGCAAGGGAAGAGGGCATAGATC
TTGAGAAGTTTATCAAGGGTTTAGGTGTACCAGCCTATCTTTCAACGAGGCTAGATGCGCCCTATGCGAGTAGTAGCCGT
GCACCATGGGCAATGGTTGTTGCTCCCTGCAGTATGAAGACGTTGGCAGCATTAGCCCACGGATATAGCGATAATCTCGT
TACTCGGGCGGCACTAGCAGTGCTAAGGCTTGGCCGTAAGCTAGTCCTAGTAGTGAGGGAAACACCCCTTGGCAAGGCTG
AGCTGAGAAACATGCTGCTAGCGGCCGAAAACGGAGCCATAATACTGCCTGCTGCTCCAGCCTTCTACACGAGGCCCAGA
ACACTTAGTGATATAGTGGACTTTGTAGTGGGCAAAATACTAGACGTACTTGGTATAGAGCATAGTCTCTACCAGCGCTG
GCGCGGCTACTCGAATTCGTCATCGCCAAAGTAG

Upstream 100 bases:

>100_bases
ACTCTTAGCCGCTGGCTTACAATAGGCGAAATGGGCTCTATGCTTTGTAGCGGGTATGAAGTCTGTGAACAGCGTGCGTA
CGTGGTAGGTGGCTTAGGAT

Downstream 100 bases:

>100_bases
CCCTTGCGTTTCATCAGCTTTTCTATCTTTGACATGGCCTCCTCTTCAGCCCTAATCTCTCTCTCTAGATCCTCGATCCG
GGTCTCTTGAGTTTGCTTCT

Product: flavoprotein, 3-polyprenyl-4-hydroxybenzoate decarboxylase, UbiX

Products: 2-octaprenylphenol; CO2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MLLRGRRVLVAITGASGVIYGARLVAHLAKRGLLEAVIYTPSALIVAREEGIDLEKFIKGLGVPAYLSTRLDAPYASSSR
APWAMVVAPCSMKTLAALAHGYSDNLVTRAALAVLRLGRKLVLVVRETPLGKAELRNMLLAAENGAIILPAAPAFYTRPR
TLSDIVDFVVGKILDVLGIEHSLYQRWRGYSNSSSPK

Sequences:

>Translated_197_residues
MLLRGRRVLVAITGASGVIYGARLVAHLAKRGLLEAVIYTPSALIVAREEGIDLEKFIKGLGVPAYLSTRLDAPYASSSR
APWAMVVAPCSMKTLAALAHGYSDNLVTRAALAVLRLGRKLVLVVRETPLGKAELRNMLLAAENGAIILPAAPAFYTRPR
TLSDIVDFVVGKILDVLGIEHSLYQRWRGYSNSSSPK
>Mature_197_residues
MLLRGRRVLVAITGASGVIYGARLVAHLAKRGLLEAVIYTPSALIVAREEGIDLEKFIKGLGVPAYLSTRLDAPYASSSR
APWAMVVAPCSMKTLAALAHGYSDNLVTRAALAVLRLGRKLVLVVRETPLGKAELRNMLLAAENGAIILPAAPAFYTRPR
TLSDIVDFVVGKILDVLGIEHSLYQRWRGYSNSSSPK

Specific function: Unknown

COG id: COG0163

COG function: function code H; 3-polyprenyl-4-hydroxybenzoate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polyprenyl p-hydroxybenzoate / phenylacrylic acid decarboxylases family [H]

Homologues:

Organism=Escherichia coli, GI1788650, Length=188, Percent_Identity=39.8936170212766, Blast_Score=129, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6320746, Length=187, Percent_Identity=40.1069518716578, Blast_Score=133, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003382
- InterPro:   IPR004507 [H]

Pfam domain/function: PF02441 Flavoprotein [H]

EC number: 4.1.1.- [C]

Molecular weight: Translated: 21250; Mature: 21250

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLRGRRVLVAITGASGVIYGARLVAHLAKRGLLEAVIYTPSALIVAREEGIDLEKFIKG
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHH
LGVPAYLSTRLDAPYASSSRAPWAMVVAPCSMKTLAALAHGYSDNLVTRAALAVLRLGRK
CCCCHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCE
LVLVVRETPLGKAELRNMLLAAENGAIILPAAPAFYTRPRTLSDIVDFVVGKILDVLGIE
EEEEEECCCCCHHHHHHHHEEECCCEEEEECCCCHHCCCCCHHHHHHHHHHHHHHHHCCC
HSLYQRWRGYSNSSSPK
HHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLLRGRRVLVAITGASGVIYGARLVAHLAKRGLLEAVIYTPSALIVAREEGIDLEKFIKG
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHH
LGVPAYLSTRLDAPYASSSRAPWAMVVAPCSMKTLAALAHGYSDNLVTRAALAVLRLGRK
CCCCHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCE
LVLVVRETPLGKAELRNMLLAAENGAIILPAAPAFYTRPRTLSDIVDFVVGKILDVLGIE
EEEEEECCCCCHHHHHHHHEEECCCEEEEECCCCHHCCCCCHHHHHHHHHHHHHHHHCCC
HSLYQRWRGYSNSSSPK
HHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-octaprenyl-4-hydroxybenzoate [C]

Specific reaction: 3-octaprenyl-4-hydroxybenzoate = 2-octaprenylphenol + CO2 [C]

General reaction: Carbon-Carbon Lyases; Carboxy-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]