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The map label for this gene is mraY [H]

Identifier: 124026898

GI number: 124026898

Start: 1852485

End: 1853600

Strand: Direct

Name: mraY [H]

Synonym: NATL1_21931

Alternate gene names: 124026898

Gene position: 1852485-1853600 (Clockwise)

Preceding gene: 124026897

Following gene: 124026899

Centisome position: 99.34

GC content: 26.97

Gene sequence:

>1116_bases
TTGAAAAAATCTAAAAAGCTTTTAGATATCAAAAAAGTATCATTTTACAATAGTATTAACAATCATATATTGATTTTATT
TGTATTAATAGCAAGTGCTTGTGTCTTTTCTGATTTTTATTTTAAAGCTAGTAATTTAACTATTCCTTTTATAATTACAA
CGACTGTATCATCAATTATTACTTTTATTGGTATACCTAAATTAAAAAAAATTAGGGCTAAACAAATAATTAGAGAAGAA
GGTCCAAAAAATCATTTTCTTAAGCAAGGGACTCCAACAATGGGTGGGATTTTCTTTATCCCAATTGGAATAATAATAAG
CAACATTTTATATTTTAACCAAGACAATTACGATATTATTTTGACTTTAACCTTTGTTATTATATTTTTTATGTTTATTG
GTTTTATAGATGATTTACTTAGTTTAAGAAAAAAATTGAATACTGGTTTGAGCTCTAACCAAAAAATACTTTTACAATCT
TTTATCAGTCTTATTTTTATTATTATTTGTGCTTCAAATAATTTAATACCTCAAAATATACAAATAGCTAATAAAGTATT
TAATATAGGAAATATAATTTATCCTTTAGGAATATTTGTATTATTAGCGGAAAGTAATTCAACGAATTTGACGGATGGTT
TAGATGGTTTATTGAGTGGCTGTAGCGTATTAATTTTCACAGGCCTAGCTATCAGTATTTTAATTGAAAATCCAAGTAAT
AATTTTACGCTCGCTCCTCTCTGCATAGTAATGGCTGGCGCTTGTATGGGATTTCTTTTTCTGAACAAATATCCTGCAAA
ATTATTTATGGGAGATTCAGGTTCCTTAGCTATAGGAGCATCCCTAGGTGGTATAGCTTTAATATCAAATCATCTTTGGT
CTCTTTTAATTATGGGGGGGATACTTGCCGCAGAATCTATCTCAGTAATCATACAAGTAAGTATTTTTAAAATTTCTAAA
CGAGTAAAGGGAAAGGGTCATAAATTATTTTTAATGACTCCGTTACATCACCATTTTGAACTTAAAGGTAACAATGAGAG
TTTAATTGTAAGTAGCTTTTGGTTAATTACATTATTCTTAGTCATAATCAATCTAATTTTTTTAATTAAATCCTAA

Upstream 100 bases:

>100_bases
GAAGAAGAGCTTTCAGCTTTAATGGGAGAAAAAGAAGACTATAAGGCTGAAGAAGAACCAACCGATGAAGAATGGGAAGA
TTAATTTACTAGCTTAAATT

Downstream 100 bases:

>100_bases
CTGTTTAAATTGAAAAGATGACCTATTTTACTTGGAAAGAAGAAGGACTAACTAAAGACTGTGAAACTTTAGATTCTATG
GCCGCTCGATTTGAAGAATC

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MKKSKKLLDIKKVSFYNSINNHILILFVLIASACVFSDFYFKASNLTIPFIITTTVSSIITFIGIPKLKKIRAKQIIREE
GPKNHFLKQGTPTMGGIFFIPIGIIISNILYFNQDNYDIILTLTFVIIFFMFIGFIDDLLSLRKKLNTGLSSNQKILLQS
FISLIFIIICASNNLIPQNIQIANKVFNIGNIIYPLGIFVLLAESNSTNLTDGLDGLLSGCSVLIFTGLAISILIENPSN
NFTLAPLCIVMAGACMGFLFLNKYPAKLFMGDSGSLAIGASLGGIALISNHLWSLLIMGGILAAESISVIIQVSIFKISK
RVKGKGHKLFLMTPLHHHFELKGNNESLIVSSFWLITLFLVIINLIFLIKS

Sequences:

>Translated_371_residues
MKKSKKLLDIKKVSFYNSINNHILILFVLIASACVFSDFYFKASNLTIPFIITTTVSSIITFIGIPKLKKIRAKQIIREE
GPKNHFLKQGTPTMGGIFFIPIGIIISNILYFNQDNYDIILTLTFVIIFFMFIGFIDDLLSLRKKLNTGLSSNQKILLQS
FISLIFIIICASNNLIPQNIQIANKVFNIGNIIYPLGIFVLLAESNSTNLTDGLDGLLSGCSVLIFTGLAISILIENPSN
NFTLAPLCIVMAGACMGFLFLNKYPAKLFMGDSGSLAIGASLGGIALISNHLWSLLIMGGILAAESISVIIQVSIFKISK
RVKGKGHKLFLMTPLHHHFELKGNNESLIVSSFWLITLFLVIINLIFLIKS
>Mature_371_residues
MKKSKKLLDIKKVSFYNSINNHILILFVLIASACVFSDFYFKASNLTIPFIITTTVSSIITFIGIPKLKKIRAKQIIREE
GPKNHFLKQGTPTMGGIFFIPIGIIISNILYFNQDNYDIILTLTFVIIFFMFIGFIDDLLSLRKKLNTGLSSNQKILLQS
FISLIFIIICASNNLIPQNIQIANKVFNIGNIIYPLGIFVLLAESNSTNLTDGLDGLLSGCSVLIFTGLAISILIENPSN
NFTLAPLCIVMAGACMGFLFLNKYPAKLFMGDSGSLAIGASLGGIALISNHLWSLLIMGGILAAESISVIIQVSIFKISK
RVKGKGHKLFLMTPLHHHFELKGNNESLIVSSFWLITLFLVIINLIFLIKS

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=321, Percent_Identity=35.8255451713396, Blast_Score=184, Evalue=8e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 40973; Mature: 40973

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSKKLLDIKKVSFYNSINNHILILFVLIASACVFSDFYFKASNLTIPFIITTTVSSII
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEECCCEEEEEHHHHHHHHH
TFIGIPKLKKIRAKQIIREEGPKNHFLKQGTPTMGGIFFIPIGIIISNILYFNQDNYDII
HHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCEEE
LTLTFVIIFFMFIGFIDDLLSLRKKLNTGLSSNQKILLQSFISLIFIIICASNNLIPQNI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCH
QIANKVFNIGNIIYPLGIFVLLAESNSTNLTDGLDGLLSGCSVLIFTGLAISILIENPSN
HHHHHHHHHCHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEEECCCC
NFTLAPLCIVMAGACMGFLFLNKYPAKLFMGDSGSLAIGASLGGIALISNHLWSLLIMGG
CEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHH
ILAAESISVIIQVSIFKISKRVKGKGHKLFLMTPLHHHFELKGNNESLIVSSFWLITLFL
HHHHHHHEEEEEEHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCEEEHHHHHHHHHHH
VIINLIFLIKS
HHHHHHHHHCC
>Mature Secondary Structure
MKKSKKLLDIKKVSFYNSINNHILILFVLIASACVFSDFYFKASNLTIPFIITTTVSSII
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEECCCEEEEEHHHHHHHHH
TFIGIPKLKKIRAKQIIREEGPKNHFLKQGTPTMGGIFFIPIGIIISNILYFNQDNYDII
HHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCEEE
LTLTFVIIFFMFIGFIDDLLSLRKKLNTGLSSNQKILLQSFISLIFIIICASNNLIPQNI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCH
QIANKVFNIGNIIYPLGIFVLLAESNSTNLTDGLDGLLSGCSVLIFTGLAISILIENPSN
HHHHHHHHHCHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEEECCCC
NFTLAPLCIVMAGACMGFLFLNKYPAKLFMGDSGSLAIGASLGGIALISNHLWSLLIMGG
CEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHH
ILAAESISVIIQVSIFKISKRVKGKGHKLFLMTPLHHHFELKGNNESLIVSSFWLITLFL
HHHHHHHEEEEEEHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCEEEHHHHHHHHHHH
VIINLIFLIKS
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA