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The map label for this gene is infC

Identifier: 124026795

GI number: 124026795

Start: 1732321

End: 1732929

Strand: Direct

Name: infC

Synonym: NATL1_20901

Alternate gene names: 124026795

Gene position: 1732321-1732929 (Clockwise)

Preceding gene: 124026794

Following gene: 124026796

Centisome position: 92.9

GC content: 38.75

Gene sequence:

>609_bases
ATGCCACCACGTCCCCGTTTTGATCGTCACGCTCCAGAAAGGGAGTTGCCCAACATTAATGAAAGAATCAGCTATTCAAG
CTTAAGGGTTGTTGATTCTGATGGCACTCAACTTGGTGTCATCAGTCGAGAGGAAGCTCTAGAGGTCGCTAAAGAGAGAG
AATTAGATCTTGTTTTGGTAAGTGAGAAGGCCACTCCTCCTGTATGCCGGATAATGAATTATGGAAAATTCAAGTTTGAG
CAAGAAAAAAAAGCAAAGGAAGCTAAGAAAAAATCACACCAAACAGAAGTTAAAGAAGTAAAAATGAGGTATAAAATTGA
CCAGCATGATTATCAGGTCCGTATTAGTCAGGCCACGAGATTCTTAAAAGCTGGAGATAAAGTCAAATGCACGGTTATAT
TCAGAGGCCGCGAAATTCAACACACTGCTCTAGCAGAAACTCTTCTAAAAAGAATGTCAAAGGATTTGGAAGAAAAGGCT
GAAGTACAACAATCCCCTAAAAGAGAGGGAAGAAATATGATTATGTTTTTAACTCCGCGTAAAACTCCTCTTTTAAAGAA
GGAGAGTGAAACAACTGAACCAAAAAAAGCTTTGAGATCAATTAATTAA

Upstream 100 bases:

>100_bases
ACCCGAAGCTTTAACTTCTATCTATGAGTTTCTAGGTTGATTAGATCATATATGATTAGAATTGCTCCAAAAGATTCTTT
CCACGTTAATTAATTACTGA

Downstream 100 bases:

>100_bases
ATCAAACAAAATTGTCATATGACAAACAAATAATTGTCACTAGCAATTCTTTTCATTAATCTAGCCCCAATCACACCTGG
CATACAAACGCGTGAGATTC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MPPRPRFDRHAPERELPNINERISYSSLRVVDSDGTQLGVISREEALEVAKERELDLVLVSEKATPPVCRIMNYGKFKFE
QEKKAKEAKKKSHQTEVKEVKMRYKIDQHDYQVRISQATRFLKAGDKVKCTVIFRGREIQHTALAETLLKRMSKDLEEKA
EVQQSPKREGRNMIMFLTPRKTPLLKKESETTEPKKALRSIN

Sequences:

>Translated_202_residues
MPPRPRFDRHAPERELPNINERISYSSLRVVDSDGTQLGVISREEALEVAKERELDLVLVSEKATPPVCRIMNYGKFKFE
QEKKAKEAKKKSHQTEVKEVKMRYKIDQHDYQVRISQATRFLKAGDKVKCTVIFRGREIQHTALAETLLKRMSKDLEEKA
EVQQSPKREGRNMIMFLTPRKTPLLKKESETTEPKKALRSIN
>Mature_201_residues
PPRPRFDRHAPERELPNINERISYSSLRVVDSDGTQLGVISREEALEVAKERELDLVLVSEKATPPVCRIMNYGKFKFEQ
EKKAKEAKKKSHQTEVKEVKMRYKIDQHDYQVRISQATRFLKAGDKVKCTVIFRGREIQHTALAETLLKRMSKDLEEKAE
VQQSPKREGRNMIMFLTPRKTPLLKKESETTEPKKALRSIN

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=167, Percent_Identity=49.1017964071856, Blast_Score=138, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_PROM1 (A2C586)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001015910.1
- ProteinModelPortal:   A2C586
- STRING:   A2C586
- GeneID:   4779060
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_20901
- eggNOG:   COG0290
- HOGENOM:   HBG744268
- OMA:   APKAPIN
- ProtClustDB:   PRK00028
- BioCyc:   PMAR167555:NATL1_20901-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 23534; Mature: 23402

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPRPRFDRHAPERELPNINERISYSSLRVVDSDGTQLGVISREEALEVAKERELDLVLV
CCCCCCCCCCCCCCCCCCCHHHCCCCEEEEEECCCCEEEEECHHHHHHHHHHCCCCEEEE
SEKATPPVCRIMNYGKFKFEQEKKAKEAKKKSHQTEVKEVKMRYKIDQHDYQVRISQATR
ECCCCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHEEEHHHHHH
FLKAGDKVKCTVIFRGREIQHTALAETLLKRMSKDLEEKAEVQQSPKREGRNMIMFLTPR
HHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCEEEEECCC
KTPLLKKESETTEPKKALRSIN
CCCCCCCCCCCCCHHHHHHCCC
>Mature Secondary Structure 
PPRPRFDRHAPERELPNINERISYSSLRVVDSDGTQLGVISREEALEVAKERELDLVLV
CCCCCCCCCCCCCCCCCCHHHCCCCEEEEEECCCCEEEEECHHHHHHHHHHCCCCEEEE
SEKATPPVCRIMNYGKFKFEQEKKAKEAKKKSHQTEVKEVKMRYKIDQHDYQVRISQATR
ECCCCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHEEEHHHHHH
FLKAGDKVKCTVIFRGREIQHTALAETLLKRMSKDLEEKAEVQQSPKREGRNMIMFLTPR
HHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCEEEEECCC
KTPLLKKESETTEPKKALRSIN
CCCCCCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA