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The map label for this gene is btuE [C]

Identifier: 124026789

GI number: 124026789

Start: 1727688

End: 1728164

Strand: Direct

Name: btuE [C]

Synonym: NATL1_20841

Alternate gene names: 124026789

Gene position: 1727688-1728164 (Clockwise)

Preceding gene: 124026786

Following gene: 124026794

Centisome position: 92.65

GC content: 34.8

Gene sequence:

>477_bases
ATGTCCGTAAATATCAGCAAAGTGGAGGTCTTCTCTTTTAAAAATCAGAAAATAACTTTTGATCATTACAAAGGAAATGT
CTTATTGATTGTCAATGTCGCAAGCAAGTGCGGGTTTACTAAGCAATATAAAGCTCTTCAGTATCTTCAGGATAAATATG
AATCCAAAGGCTTCAAAGTTTTAGGCTTTCCTTGTAATGACTTTGGAAACCAAGAGCCTGGGCAATTAGAAGAAATAAAA
GAGTTCTGTTCAACAACTTATGGAGTAACTTTCCAACTTTTCCAAAAAGTTCATGCCAAAGGCAAAACAACAGAACCATT
TACTACTTTGAATCAATTAAGTCCATCCGGAGACGTTGAATGGAACTTTGAGAAATTTCTCATTAATACTGAGGGAGATG
CGGTCTTAAGATTTAAAAGTTCAATAGAACCTGACAGTCCTGAAATCACACAAGCAATCGAAAAATTACTCGATTAA

Upstream 100 bases:

>100_bases
ATTGAGTCTCACGAGATGCCCCTATTTCTTCGTTCATATTTGGAGCAGCAAGCCATTATTATTTTATGGCTAACTCCCGT
TTTTTATCACTTCCATATCC

Downstream 100 bases:

>100_bases
GCATTTAATTTCTTAGCAAAGATGTGGCCTAAAGCAATAGCTAAAACTCCCATAAGTACAATTGATATGGAGTTAAATAA
AAACAATTTATACAGGCGTT

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MSVNISKVEVFSFKNQKITFDHYKGNVLLIVNVASKCGFTKQYKALQYLQDKYESKGFKVLGFPCNDFGNQEPGQLEEIK
EFCSTTYGVTFQLFQKVHAKGKTTEPFTTLNQLSPSGDVEWNFEKFLINTEGDAVLRFKSSIEPDSPEITQAIEKLLD

Sequences:

>Translated_158_residues
MSVNISKVEVFSFKNQKITFDHYKGNVLLIVNVASKCGFTKQYKALQYLQDKYESKGFKVLGFPCNDFGNQEPGQLEEIK
EFCSTTYGVTFQLFQKVHAKGKTTEPFTTLNQLSPSGDVEWNFEKFLINTEGDAVLRFKSSIEPDSPEITQAIEKLLD
>Mature_157_residues
SVNISKVEVFSFKNQKITFDHYKGNVLLIVNVASKCGFTKQYKALQYLQDKYESKGFKVLGFPCNDFGNQEPGQLEEIKE
FCSTTYGVTFQLFQKVHAKGKTTEPFTTLNQLSPSGDVEWNFEKFLINTEGDAVLRFKSSIEPDSPEITQAIEKLLD

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=150, Percent_Identity=40.6666666666667, Blast_Score=111, Evalue=2e-25,
Organism=Homo sapiens, GI192455698, Length=152, Percent_Identity=36.8421052631579, Blast_Score=101, Evalue=4e-22,
Organism=Homo sapiens, GI75709200, Length=134, Percent_Identity=39.5522388059701, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI90903240, Length=134, Percent_Identity=39.5522388059701, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI4557629, Length=149, Percent_Identity=37.5838926174497, Blast_Score=91, Evalue=4e-19,
Organism=Homo sapiens, GI90903238, Length=116, Percent_Identity=39.6551724137931, Blast_Score=88, Evalue=3e-18,
Organism=Homo sapiens, GI6006001, Length=145, Percent_Identity=36.551724137931, Blast_Score=85, Evalue=3e-17,
Organism=Homo sapiens, GI33186887, Length=145, Percent_Identity=36.551724137931, Blast_Score=77, Evalue=7e-15,
Organism=Homo sapiens, GI32967607, Length=172, Percent_Identity=33.7209302325581, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI41406084, Length=164, Percent_Identity=32.9268292682927, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788003, Length=163, Percent_Identity=40.4907975460123, Blast_Score=133, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI193210707, Length=150, Percent_Identity=40.6666666666667, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17506887, Length=163, Percent_Identity=37.4233128834356, Blast_Score=96, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71993584, Length=146, Percent_Identity=34.2465753424658, Blast_Score=96, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17535473, Length=147, Percent_Identity=34.6938775510204, Blast_Score=96, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI193209493, Length=180, Percent_Identity=30.5555555555556, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17550320, Length=181, Percent_Identity=27.6243093922652, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71993573, Length=82, Percent_Identity=37.8048780487805, Blast_Score=63, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6319721, Length=162, Percent_Identity=45.0617283950617, Blast_Score=139, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6322228, Length=149, Percent_Identity=46.3087248322148, Blast_Score=138, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6322826, Length=144, Percent_Identity=42.3611111111111, Blast_Score=118, Evalue=5e-28,
Organism=Drosophila melanogaster, GI85726443, Length=142, Percent_Identity=39.4366197183099, Blast_Score=103, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24656772, Length=163, Percent_Identity=34.3558282208589, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24656777, Length=163, Percent_Identity=34.3558282208589, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24656767, Length=163, Percent_Identity=34.3558282208589, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 17969; Mature: 17837

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVNISKVEVFSFKNQKITFDHYKGNVLLIVNVASKCGFTKQYKALQYLQDKYESKGFKV
CCCCCCEEEEEEECCCEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEE
LGFPCNDFGNQEPGQLEEIKEFCSTTYGVTFQLFQKVHAKGKTTEPFTTLNQLSPSGDVE
EEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCE
WNFEKFLINTEGDAVLRFKSSIEPDSPEITQAIEKLLD
ECEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SVNISKVEVFSFKNQKITFDHYKGNVLLIVNVASKCGFTKQYKALQYLQDKYESKGFKV
CCCCCEEEEEEECCCEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEE
LGFPCNDFGNQEPGQLEEIKEFCSTTYGVTFQLFQKVHAKGKTTEPFTTLNQLSPSGDVE
EEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCE
WNFEKFLINTEGDAVLRFKSSIEPDSPEITQAIEKLLD
ECEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]