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The map label for this gene is ruvB

Identifier: 124026772

GI number: 124026772

Start: 1711963

End: 1713033

Strand: Reverse

Name: ruvB

Synonym: NATL1_20671

Alternate gene names: 124026772

Gene position: 1713033-1711963 (Counterclockwise)

Preceding gene: 124026774

Following gene: 124026771

Centisome position: 91.86

GC content: 37.91

Gene sequence:

>1071_bases
ATGGCAATTGTGTCTTCAATTACTAATCATTCTTCTCTTCCTAATGATAAAGGAGAGGAAAGATTGGTTGGTCCCAGCCT
TTTAAGAGAGGAGCTTAAATTATCTCAACAAGATTCACTCAGGCCTAAATCTTTTGATGATTTTGTAGGTCAATCTGAAT
TAAAAAAAGTTCTTGAGATTTCAGTTAAAGCATCATTAAAAAGAGGAGAAGCACTTGATCATTTAATGCTTTATGGGCCG
CCAGGATTGGGAAAAACTACCATGGCTCTTGTTATTGCTGAGGAATTGGGGGTTAAAGCTAGAGTTACAAGCGCTCCTGC
TCTTGAACGACCAAGGGATATTGTTGGATTATTGATTAATATGCAGCCACGTGAATTGATTTTTGTTGATGAGATTCACA
GACTCAATCGCATATCACAGGAACTTTTGTATCCAGCTATGGAAGATAGAAGGTTAGATTTAACTGTAGGTAAGGGTACT
TCTTCCAGAATGCGATCAATAGAAATCCCCCCTTTTACCTTAGTAGGTGCAACTACAAAACCTGCAGCATTAAGCTCCCC
TATGCGAGATCGTTTTGGCATAACTCAGCGACTAGATTTTTACAATTATTTGGACCTTGAAAATATAATTAAAAGATCTG
CGAAACTTATTAATTTAGTAATTTCAGAGGAAGCATCTCAACAATTAGCCAAAAGATGTCGAGGAACTCCTCGGATTGCA
AATAGGCTCATACGAAGAGTTAGAGATTATGCAGAAGTGTATTCTCATTCAAAGAAGATCGATGTTGAAGTTGTAAACGA
TGCACTTGATCTTCATCGTGTGGATCAAAGAGGTCTTGATGCAACAGATAGAAGTTATATAGGCTTGTTAGTTAATCAAT
ATCAAGGAGGCCCAGTAGGGCTGGAGACTTTGGCTGCTGGACTTGGAGAGGATTCAACGACCCTTGAAACTGTAGTTGAG
CCTTATCTAATGCAAATTGGTTTTTTACAGAGAACTTCTAGGGGAAGGGTTGTTACTCCAGCAGCTAAAAAACATTATTT
ACTAACTTCCCCAAATAATATAGATAAATGA

Upstream 100 bases:

>100_bases
TTTCCATCAACTGAGGAATTGTTTTTGGATTTTTTCTTTCCTTTTTTGCTCATTCTTCTATTTACCTACATTTTTGTTTA
GATGCCACTACCCTTTAATC

Downstream 100 bases:

>100_bases
TTTTGGGAAGATTTGTTAAAGTTCTACTTTTACTTTCTATTATTTTTGTTGTCGTTCCATTGTCGACCCAAGCTAAAGTG
CTTCCTAAAGTTTTATTCGA

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MAIVSSITNHSSLPNDKGEERLVGPSLLREELKLSQQDSLRPKSFDDFVGQSELKKVLEISVKASLKRGEALDHLMLYGP
PGLGKTTMALVIAEELGVKARVTSAPALERPRDIVGLLINMQPRELIFVDEIHRLNRISQELLYPAMEDRRLDLTVGKGT
SSRMRSIEIPPFTLVGATTKPAALSSPMRDRFGITQRLDFYNYLDLENIIKRSAKLINLVISEEASQQLAKRCRGTPRIA
NRLIRRVRDYAEVYSHSKKIDVEVVNDALDLHRVDQRGLDATDRSYIGLLVNQYQGGPVGLETLAAGLGEDSTTLETVVE
PYLMQIGFLQRTSRGRVVTPAAKKHYLLTSPNNIDK

Sequences:

>Translated_356_residues
MAIVSSITNHSSLPNDKGEERLVGPSLLREELKLSQQDSLRPKSFDDFVGQSELKKVLEISVKASLKRGEALDHLMLYGP
PGLGKTTMALVIAEELGVKARVTSAPALERPRDIVGLLINMQPRELIFVDEIHRLNRISQELLYPAMEDRRLDLTVGKGT
SSRMRSIEIPPFTLVGATTKPAALSSPMRDRFGITQRLDFYNYLDLENIIKRSAKLINLVISEEASQQLAKRCRGTPRIA
NRLIRRVRDYAEVYSHSKKIDVEVVNDALDLHRVDQRGLDATDRSYIGLLVNQYQGGPVGLETLAAGLGEDSTTLETVVE
PYLMQIGFLQRTSRGRVVTPAAKKHYLLTSPNNIDK
>Mature_355_residues
AIVSSITNHSSLPNDKGEERLVGPSLLREELKLSQQDSLRPKSFDDFVGQSELKKVLEISVKASLKRGEALDHLMLYGPP
GLGKTTMALVIAEELGVKARVTSAPALERPRDIVGLLINMQPRELIFVDEIHRLNRISQELLYPAMEDRRLDLTVGKGTS
SRMRSIEIPPFTLVGATTKPAALSSPMRDRFGITQRLDFYNYLDLENIIKRSAKLINLVISEEASQQLAKRCRGTPRIAN
RLIRRVRDYAEVYSHSKKIDVEVVNDALDLHRVDQRGLDATDRSYIGLLVNQYQGGPVGLETLAAGLGEDSTTLETVVEP
YLMQIGFLQRTSRGRVVTPAAKKHYLLTSPNNIDK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=313, Percent_Identity=50.1597444089457, Blast_Score=347, Evalue=9e-97,
Organism=Escherichia coli, GI1787119, Length=242, Percent_Identity=27.2727272727273, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_PROM1 (A2C563)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001015887.1
- ProteinModelPortal:   A2C563
- SMR:   A2C563
- STRING:   A2C563
- GeneID:   4780105
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_20671
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- BioCyc:   PMAR167555:NATL1_20671-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 39737; Mature: 39606

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIVSSITNHSSLPNDKGEERLVGPSLLREELKLSQQDSLRPKSFDDFVGQSELKKVLEI
CCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHCCCCCCHHHHCCHHHHHHHHHH
SVKASLKRGEALDHLMLYGPPGLGKTTMALVIAEELGVKARVTSAPALERPRDIVGLLIN
HHHHHHHCCCCHHHEEEECCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHCC
MQPRELIFVDEIHRLNRISQELLYPAMEDRRLDLTVGKGTSSRMRSIEIPPFTLVGATTK
CCCCCEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHCEEECCCCEEEECCCCC
PAALSSPMRDRFGITQRLDFYNYLDLENIIKRSAKLINLVISEEASQQLAKRCRGTPRIA
CHHHCCCHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
NRLIRRVRDYAEVYSHSKKIDVEVVNDALDLHRVDQRGLDATDRSYIGLLVNQYQGGPVG
HHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCC
LETLAAGLGEDSTTLETVVEPYLMQIGFLQRTSRGRVVTPAAKKHYLLTSPNNIDK
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCEEEECCCCCCC
>Mature Secondary Structure 
AIVSSITNHSSLPNDKGEERLVGPSLLREELKLSQQDSLRPKSFDDFVGQSELKKVLEI
CHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHCCCCCCHHHHCCHHHHHHHHHH
SVKASLKRGEALDHLMLYGPPGLGKTTMALVIAEELGVKARVTSAPALERPRDIVGLLIN
HHHHHHHCCCCHHHEEEECCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHCC
MQPRELIFVDEIHRLNRISQELLYPAMEDRRLDLTVGKGTSSRMRSIEIPPFTLVGATTK
CCCCCEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHCEEECCCCEEEECCCCC
PAALSSPMRDRFGITQRLDFYNYLDLENIIKRSAKLINLVISEEASQQLAKRCRGTPRIA
CHHHCCCHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
NRLIRRVRDYAEVYSHSKKIDVEVVNDALDLHRVDQRGLDATDRSYIGLLVNQYQGGPVG
HHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCC
LETLAAGLGEDSTTLETVVEPYLMQIGFLQRTSRGRVVTPAAKKHYLLTSPNNIDK
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA