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The map label for this gene is ho1 [H]

Identifier: 124026749

GI number: 124026749

Start: 1686711

End: 1687418

Strand: Reverse

Name: ho1 [H]

Synonym: NATL1_20441

Alternate gene names: 124026749

Gene position: 1687418-1686711 (Counterclockwise)

Preceding gene: 124026751

Following gene: 124026748

Centisome position: 90.49

GC content: 33.62

Gene sequence:

>708_bases
ATGGCACTAGCCTTCGCTAGGCAACTTCGTGAAGGGACTAAAAAGTCTCATACGATGGCTGAAAATACAGGTTTTATAAG
TTGTTTCCTCAAGGGCGTAGTTGATAAGTCCTCATACAGAAATTTATTAGCTGATTTATATTTTGTTTACTCTGCGATGG
AGGAAGAGATAGAAAAACTTTGTGAAAATTCTCATCCGATAATTTCTCCAATTGGATTTAAAGAGCTTTTTCGTAAGAAA
AAATTAGAGCAAGATTTGTCGTTCTACTTTGGTAGTAATTGGTCTGAATTGGTAAAACCCTCAAAGCCAGCTGTTGAATA
TGAAGCAAGAATTCGAGAAATCGCGAAAGATAATCCTGAACTTTTAATTGGGCATCATTACAGCCGATATATAGGTGACT
TGTCTGGAGGACAGCTTTTGAAAACAATTACTAAAAAAGCCATGAATCTTCCTGGGGATGATGGACTTAGCTTTTATATT
TTTGAGGAAATCAGCGATGAAAAAGAATTTAAGATTAAGTATAGAAATACCCTGGATAATCTTCCTATTGATCAAAAGAT
AGCAGATTCAATTATAGAAGAGGCCAATAGATCTTTTAAATATAATATGGATATTTTTAATGAATTAGAAGGAAATTTAA
TTGCAGCAATAGGGAAAGTTTTATTTAGATTTTTTGCAAATAAAAAGCGAAAAGGTAGCACGGAGTAG

Upstream 100 bases:

>100_bases
AAGCTTTTCAAAATTTGCCATGATTTTTATTCAACGATTAAGTCATCTAATGTTGAGCTTATGTCTAAGTGGTAAGTTTT
GATTAAATGATTTTGAACTC

Downstream 100 bases:

>100_bases
TAAAATTTATATTTTTTTTATGATCATTATTTTATTTATATTCATTATCTATTAAGATATCTATTATGAAATATAAAAGT
GTAAAAGTTTTGTATTTATT

Product: Heme oxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MALAFARQLREGTKKSHTMAENTGFISCFLKGVVDKSSYRNLLADLYFVYSAMEEEIEKLCENSHPIISPIGFKELFRKK
KLEQDLSFYFGSNWSELVKPSKPAVEYEARIREIAKDNPELLIGHHYSRYIGDLSGGQLLKTITKKAMNLPGDDGLSFYI
FEEISDEKEFKIKYRNTLDNLPIDQKIADSIIEEANRSFKYNMDIFNELEGNLIAAIGKVLFRFFANKKRKGSTE

Sequences:

>Translated_235_residues
MALAFARQLREGTKKSHTMAENTGFISCFLKGVVDKSSYRNLLADLYFVYSAMEEEIEKLCENSHPIISPIGFKELFRKK
KLEQDLSFYFGSNWSELVKPSKPAVEYEARIREIAKDNPELLIGHHYSRYIGDLSGGQLLKTITKKAMNLPGDDGLSFYI
FEEISDEKEFKIKYRNTLDNLPIDQKIADSIIEEANRSFKYNMDIFNELEGNLIAAIGKVLFRFFANKKRKGSTE
>Mature_234_residues
ALAFARQLREGTKKSHTMAENTGFISCFLKGVVDKSSYRNLLADLYFVYSAMEEEIEKLCENSHPIISPIGFKELFRKKK
LEQDLSFYFGSNWSELVKPSKPAVEYEARIREIAKDNPELLIGHHYSRYIGDLSGGQLLKTITKKAMNLPGDDGLSFYIF
EEISDEKEFKIKYRNTLDNLPIDQKIADSIIEEANRSFKYNMDIFNELEGNLIAAIGKVLFRFFANKKRKGSTE

Specific function: Catalyzes the opening of the heme ring with the release of iron. Key enzyme in the synthesis of the chromophoric part of the photosynthetic antennas. Upon overexpression in E.coli with PCB:ferredoxin oxidoreductase, CpeS and either CpcB or PecB permits sy

COG id: COG5398

COG function: function code P; Heme oxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme oxygenase family [H]

Homologues:

Organism=Homo sapiens, GI187761311, Length=204, Percent_Identity=45.5882352941176, Blast_Score=192, Evalue=2e-49,
Organism=Homo sapiens, GI187761309, Length=204, Percent_Identity=45.5882352941176, Blast_Score=192, Evalue=2e-49,
Organism=Homo sapiens, GI187761307, Length=204, Percent_Identity=45.5882352941176, Blast_Score=192, Evalue=2e-49,
Organism=Homo sapiens, GI8051608, Length=204, Percent_Identity=45.5882352941176, Blast_Score=192, Evalue=2e-49,
Organism=Homo sapiens, GI4504437, Length=213, Percent_Identity=41.7840375586854, Blast_Score=179, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002051
- InterPro:   IPR016053
- InterPro:   IPR016084
- InterPro:   IPR018207 [H]

Pfam domain/function: PF01126 Heme_oxygenase [H]

EC number: =1.14.99.3 [H]

Molecular weight: Translated: 27023; Mature: 26892

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALAFARQLREGTKKSHTMAENTGFISCFLKGVVDKSSYRNLLADLYFVYSAMEEEIEKL
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
CENSHPIISPIGFKELFRKKKLEQDLSFYFGSNWSELVKPSKPAVEYEARIREIAKDNPE
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHCCCCC
LLIGHHYSRYIGDLSGGQLLKTITKKAMNLPGDDGLSFYIFEEISDEKEFKIKYRNTLDN
EEECCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHEEEEHHHHHCC
LPIDQKIADSIIEEANRSFKYNMDIFNELEGNLIAAIGKVLFRFFANKKRKGSTE
CCCCHHHHHHHHHHHCCCEEECHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ALAFARQLREGTKKSHTMAENTGFISCFLKGVVDKSSYRNLLADLYFVYSAMEEEIEKL
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
CENSHPIISPIGFKELFRKKKLEQDLSFYFGSNWSELVKPSKPAVEYEARIREIAKDNPE
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHCCCCC
LLIGHHYSRYIGDLSGGQLLKTITKKAMNLPGDDGLSFYIFEEISDEKEFKIKYRNTLDN
EEECCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHEEEEHHHHHCC
LPIDQKIADSIIEEANRSFKYNMDIFNELEGNLIAAIGKVLFRFFANKKRKGSTE
CCCCHHHHHHHHHHHCCCEEECHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]