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The map label for this gene is ureD

Identifier: 124026628

GI number: 124026628

Start: 1582486

End: 1583409

Strand: Direct

Name: ureD

Synonym: NATL1_19231

Alternate gene names: 124026628

Gene position: 1582486-1583409 (Clockwise)

Preceding gene: 124026619

Following gene: 124026629

Centisome position: 84.86

GC content: 34.85

Gene sequence:

>924_bases
ATGAAATCTCAATGGCATGGAACTTGTGATCTAAGGCTTTTCAAAAGCTCAAGGTCTAACAATAAAGATGTTGTCAAAAC
AATTCATCAAGCGAAATGTACTGCTCCATTAAAAGTAATGAGAGTATTTAATGATAAAAAAGATGGGAGATGTGAAATAC
CAATTCTCCATAGTGCTGGAGGAATTGTTGGAGGTGATCAACTAACAATAAATGTAAATGCCGAAGAAGATAGCATTGCT
ATATGTTCTTCAGTCGCAGCTCAAAAAGTTTATGGAAGTAGAGGCAGATCAAAATTAAATCCGCAAGGGAGCTGGGCAAA
TCAAAAATGCTTTTTCCAAATTAAAAAAAATTCTGACTTTGAGTGGATCCCTCAAGAATTAATTGTTTATCAGGGAGGTC
TTTTTGAACAAAATATGACTGTTAATCTTGATCTTTCATCAAGCTTTTTATGTGTTGATTTGGTTCGCTTGGGACGAACT
GCTGCAGAAGAACAACTTGGTAATGGAGTATGGAGATCATCTTTGGAAATCTTTAGGGATAATAATCAAGGAAAACATTA
TGAATTTAGTGATCGCTTAGAACTATCTGGAGAAGCTCTAAAATCCATTCATGGCTTAGAACAGAAACCAGTATTTGGAT
CTTTAACTTGGATAACACCTAAAAAAATAAAGCAAAAAGATTTGTCTGATTTACTAGTCGAATGTCGAGAACAAAGAGCT
GGACTTGAGGGATTTATGACTTGTAGTCTTCTTGAAAATGGCATCTCAGCAAGATACACTGGCTCATCAACACAATCAGC
TCGATTTTGGTTTTATAGAATTTGGAGTCTTACTAGAATTTTAAGAAAATTAAGCATGCCTGAATATATGAGGATTTGGC
CCATGCAAGAAAATCCATCAAGAGATAAAAAATGTCCATCATGA

Upstream 100 bases:

>100_bases
TTAAATTCTTTGTAGACCTAAATTTTATAGGTTATGTCTGCCAGATCAGACATTTATTATTTTCTCAAAACTAAATAAGC
ACAAACGATAAAGCTATTCA

Downstream 100 bases:

>100_bases
ACTTTTAAGCATTTTTTTGCTAGTAAAATTAACGTCTAACTATTAAAAAATGTACTTAAGCCCTCAAGAAAAAGACAAAT
TACTTGTGGTTACTGCTGCT

Product: urease accessory protein UreD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MKSQWHGTCDLRLFKSSRSNNKDVVKTIHQAKCTAPLKVMRVFNDKKDGRCEIPILHSAGGIVGGDQLTINVNAEEDSIA
ICSSVAAQKVYGSRGRSKLNPQGSWANQKCFFQIKKNSDFEWIPQELIVYQGGLFEQNMTVNLDLSSSFLCVDLVRLGRT
AAEEQLGNGVWRSSLEIFRDNNQGKHYEFSDRLELSGEALKSIHGLEQKPVFGSLTWITPKKIKQKDLSDLLVECREQRA
GLEGFMTCSLLENGISARYTGSSTQSARFWFYRIWSLTRILRKLSMPEYMRIWPMQENPSRDKKCPS

Sequences:

>Translated_307_residues
MKSQWHGTCDLRLFKSSRSNNKDVVKTIHQAKCTAPLKVMRVFNDKKDGRCEIPILHSAGGIVGGDQLTINVNAEEDSIA
ICSSVAAQKVYGSRGRSKLNPQGSWANQKCFFQIKKNSDFEWIPQELIVYQGGLFEQNMTVNLDLSSSFLCVDLVRLGRT
AAEEQLGNGVWRSSLEIFRDNNQGKHYEFSDRLELSGEALKSIHGLEQKPVFGSLTWITPKKIKQKDLSDLLVECREQRA
GLEGFMTCSLLENGISARYTGSSTQSARFWFYRIWSLTRILRKLSMPEYMRIWPMQENPSRDKKCPS
>Mature_307_residues
MKSQWHGTCDLRLFKSSRSNNKDVVKTIHQAKCTAPLKVMRVFNDKKDGRCEIPILHSAGGIVGGDQLTINVNAEEDSIA
ICSSVAAQKVYGSRGRSKLNPQGSWANQKCFFQIKKNSDFEWIPQELIVYQGGLFEQNMTVNLDLSSSFLCVDLVRLGRT
AAEEQLGNGVWRSSLEIFRDNNQGKHYEFSDRLELSGEALKSIHGLEQKPVFGSLTWITPKKIKQKDLSDLLVECREQRA
GLEGFMTCSLLENGISARYTGSSTQSARFWFYRIWSLTRILRKLSMPEYMRIWPMQENPSRDKKCPS

Specific function: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter

COG id: COG0829

COG function: function code O; Urease accessory protein UreH

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ureD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URED_PROM1 (A2C4R9)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001015743.1
- STRING:   A2C4R9
- GeneID:   4779677
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_19231
- eggNOG:   COG0829
- HOGENOM:   HBG711156
- OMA:   NSHLEYL
- ProtClustDB:   CLSK922040
- BioCyc:   PMAR167555:NATL1_19231-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01384
- InterPro:   IPR002669

Pfam domain/function: PF01774 UreD

EC number: NA

Molecular weight: Translated: 34898; Mature: 34898

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSQWHGTCDLRLFKSSRSNNKDVVKTIHQAKCTAPLKVMRVFNDKKDGRCEIPILHSAG
CCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEEEECCC
GIVGGDQLTINVNAEEDSIAICSSVAAQKVYGSRGRSKLNPQGSWANQKCFFQIKKNSDF
CEECCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCC
EWIPQELIVYQGGLFEQNMTVNLDLSSSFLCVDLVRLGRTAAEEQLGNGVWRSSLEIFRD
CCCCHHHHHCCCCEEECCCEEEEECCCCHHHHHHHHHCCHHHHHHHCCHHHHHHHHHEEC
NNQGKHYEFSDRLELSGEALKSIHGLEQKPVFGSLTWITPKKIKQKDLSDLLVECREQRA
CCCCCCEECCCHHHCCHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHC
GLEGFMTCSLLENGISARYTGSSTQSARFWFYRIWSLTRILRKLSMPEYMRIWPMQENPS
CHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCC
RDKKCPS
CCCCCCC
>Mature Secondary Structure
MKSQWHGTCDLRLFKSSRSNNKDVVKTIHQAKCTAPLKVMRVFNDKKDGRCEIPILHSAG
CCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEEEECCC
GIVGGDQLTINVNAEEDSIAICSSVAAQKVYGSRGRSKLNPQGSWANQKCFFQIKKNSDF
CEECCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCC
EWIPQELIVYQGGLFEQNMTVNLDLSSSFLCVDLVRLGRTAAEEQLGNGVWRSSLEIFRD
CCCCHHHHHCCCCEEECCCEEEEECCCCHHHHHHHHHCCHHHHHHHCCHHHHHHHHHEEC
NNQGKHYEFSDRLELSGEALKSIHGLEQKPVFGSLTWITPKKIKQKDLSDLLVECREQRA
CCCCCCEECCCHHHCCHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHC
GLEGFMTCSLLENGISARYTGSSTQSARFWFYRIWSLTRILRKLSMPEYMRIWPMQENPS
CHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCC
RDKKCPS
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA