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The map label for this gene is codA [H]

Identifier: 124026429

GI number: 124026429

Start: 1409970

End: 1411283

Strand: Reverse

Name: codA [H]

Synonym: NATL1_17241

Alternate gene names: 124026429

Gene position: 1411283-1409970 (Counterclockwise)

Preceding gene: 124026436

Following gene: 124026428

Centisome position: 75.68

GC content: 35.39

Gene sequence:

>1314_bases
GTGACTTTAGAAAAAGAAGAATTCAATTTATCTACTAAAGCATCAGGTCGTATTGATGTGTTAGTACCGAGATGCTTGAT
TGGAGAGGGTGCAAATATTCTGGGAGTAACAGTTGACTTTGAAGGGCTATGTTCGCTTCAAGTTGAGTGGAGGCATGGAA
AAATCTGCTCAATTAAAGGTTTAAAAGATGCTTCAAAAGTTCCTAATGAAATCCTTCTACCTAGATTTTCTGAACCTCAT
GCTCATTTAGATAAAGCATTTTCATGGTCTCGAGCTCCTAATTATAAAGGGAGTTATCAAGAAGCTTTAGTAGCCAATTT
AAATGACTATAAAAGTAGGTCTCAAGGCCAATTGCTTTTTAGTGTTGAAAAATCTCTGAACCTAGCCCTTGTTAATGGTA
TCCGTGCAATTAGATCTCATATAGATAGCTTTGGAGAAAATGTAATGAGAGATTGGGACCTGTTAGATGATATTAGAAAA
AAATGGCGAGACAAAATTTTCTTACAATTTGTGGCTTTAGTCCCATTAGAATTTTGGCAAACGTATGAAGGTGAGCTTTT
AGCGCAAAGAGTTGCTTTGAATGGAGATCTCCTAGGAGGAGTCATAGCTCCTCCTTTTAATAAAAAGAAGACAATTCAGT
CTTTATTACACTTAGTTCAACTTGCAAATAGACTTAATTGTGATATTGATCTTCATATTGATGAGTCTCAGTCTTGTCCT
GCTGCAGGGGTGAAATTACTTCTTGAAGTATTAGGCCGTATTAAAAATGAGATATCAATAACATGTAGTCATTTGAGCAG
TATGGCTTTACTAAGAGAAAAATCGATTTCAAATTTGGCAAAGGAAATAGCTGAAAAGAAATTAAATGTTGTTGCTTTAC
CACTCACGAATTCTTGGCTGCTCGGTAGAAATGAACGATCTACTTCAATTAAAAGACCTCTAGCTCCAATATTTCAACTT
CAAAAGGCTGGGGTTGTTGTATCTGTAGGAGGAGACAATGTAAATGATGCATGGTTTCCATTCACTAATTTTGATCCAAT
AAATTTAATGGCTTTTTCAATGCCAATTGCTCATTTAACTCCTTGGGAGAGATTGGGCCTTTCTCCATTTACTTCATCCG
CAGCAAGTATTCTTAATCTTCAATGGGATGGCGTTTTACAAAAAGGAAGTCCTGCCGATTTTGTTTTGTTAGATTCAAAT
AGTTGGGTAAAAGCTTTGTCTGAAAGACCTAAAAGAAGAGTAGTAGTTAATGGCGAATTTTTAAATGAATTGCCTAAAAA
CAAAAAATCAACATTCAACAATTCTCACTCATGA

Upstream 100 bases:

>100_bases
TTTTTGTATGTTGATCACAACGCATTTTAAAGATATTAAAGTTACTGTGGATTTGTGAGGCCTTGAAAACAGGCTTTTGA
CTTGGTGATTGTATTTTTAA

Downstream 100 bases:

>100_bases
CTAATACAAAGAAAGTAGAGTTGCTTTTAAGTGAACTAAAATCAGTACCTGATCTAGAGATCTATCAAAAAACTAGTGAT
TTAAAAAGGTTCTCTAAAGA

Product: putative cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MTLEKEEFNLSTKASGRIDVLVPRCLIGEGANILGVTVDFEGLCSLQVEWRHGKICSIKGLKDASKVPNEILLPRFSEPH
AHLDKAFSWSRAPNYKGSYQEALVANLNDYKSRSQGQLLFSVEKSLNLALVNGIRAIRSHIDSFGENVMRDWDLLDDIRK
KWRDKIFLQFVALVPLEFWQTYEGELLAQRVALNGDLLGGVIAPPFNKKKTIQSLLHLVQLANRLNCDIDLHIDESQSCP
AAGVKLLLEVLGRIKNEISITCSHLSSMALLREKSISNLAKEIAEKKLNVVALPLTNSWLLGRNERSTSIKRPLAPIFQL
QKAGVVVSVGGDNVNDAWFPFTNFDPINLMAFSMPIAHLTPWERLGLSPFTSSAASILNLQWDGVLQKGSPADFVLLDSN
SWVKALSERPKRRVVVNGEFLNELPKNKKSTFNNSHS

Sequences:

>Translated_437_residues
MTLEKEEFNLSTKASGRIDVLVPRCLIGEGANILGVTVDFEGLCSLQVEWRHGKICSIKGLKDASKVPNEILLPRFSEPH
AHLDKAFSWSRAPNYKGSYQEALVANLNDYKSRSQGQLLFSVEKSLNLALVNGIRAIRSHIDSFGENVMRDWDLLDDIRK
KWRDKIFLQFVALVPLEFWQTYEGELLAQRVALNGDLLGGVIAPPFNKKKTIQSLLHLVQLANRLNCDIDLHIDESQSCP
AAGVKLLLEVLGRIKNEISITCSHLSSMALLREKSISNLAKEIAEKKLNVVALPLTNSWLLGRNERSTSIKRPLAPIFQL
QKAGVVVSVGGDNVNDAWFPFTNFDPINLMAFSMPIAHLTPWERLGLSPFTSSAASILNLQWDGVLQKGSPADFVLLDSN
SWVKALSERPKRRVVVNGEFLNELPKNKKSTFNNSHS
>Mature_436_residues
TLEKEEFNLSTKASGRIDVLVPRCLIGEGANILGVTVDFEGLCSLQVEWRHGKICSIKGLKDASKVPNEILLPRFSEPHA
HLDKAFSWSRAPNYKGSYQEALVANLNDYKSRSQGQLLFSVEKSLNLALVNGIRAIRSHIDSFGENVMRDWDLLDDIRKK
WRDKIFLQFVALVPLEFWQTYEGELLAQRVALNGDLLGGVIAPPFNKKKTIQSLLHLVQLANRLNCDIDLHIDESQSCPA
AGVKLLLEVLGRIKNEISITCSHLSSMALLREKSISNLAKEIAEKKLNVVALPLTNSWLLGRNERSTSIKRPLAPIFQLQ
KAGVVVSVGGDNVNDAWFPFTNFDPINLMAFSMPIAHLTPWERLGLSPFTSSAASILNLQWDGVLQKGSPADFVLLDSNS
WVKALSERPKRRVVVNGEFLNELPKNKKSTFNNSHS

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=394, Percent_Identity=24.3654822335025, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 48771; Mature: 48640

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLEKEEFNLSTKASGRIDVLVPRCLIGEGANILGVTVDFEGLCSLQVEWRHGKICSIKG
CCCCCCCCCCCCCCCCCEEEEECHHHHCCCCCEEEEEEECCCCEEEEEEECCCCEEEECC
LKDASKVPNEILLPRFSEPHAHLDKAFSWSRAPNYKGSYQEALVANLNDYKSRSQGQLLF
CCHHHHCCCHHCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHCCCCCCCEEE
SVEKSLNLALVNGIRAIRSHIDSFGENVMRDWDLLDDIRKKWRDKIFLQFVALVPLEFWQ
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TYEGELLAQRVALNGDLLGGVIAPPFNKKKTIQSLLHLVQLANRLNCDIDLHIDESQSCP
CCCHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
AAGVKLLLEVLGRIKNEISITCSHLSSMALLREKSISNLAKEIAEKKLNVVALPLTNSWL
HHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEE
LGRNERSTSIKRPLAPIFQLQKAGVVVSVGGDNVNDAWFPFTNFDPINLMAFSMPIAHLT
ECCCCCCCHHHCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCHHHCC
PWERLGLSPFTSSAASILNLQWDGVLQKGSPADFVLLDSNSWVKALSERPKRRVVVNGEF
CHHHCCCCCCCHHHHHHEEEEECCEECCCCCCCEEEECCCHHHHHHHCCCCCEEEECHHH
LNELPKNKKSTFNNSHS
HHHCCCCHHHCCCCCCC
>Mature Secondary Structure 
TLEKEEFNLSTKASGRIDVLVPRCLIGEGANILGVTVDFEGLCSLQVEWRHGKICSIKG
CCCCCCCCCCCCCCCCEEEEECHHHHCCCCCEEEEEEECCCCEEEEEEECCCCEEEECC
LKDASKVPNEILLPRFSEPHAHLDKAFSWSRAPNYKGSYQEALVANLNDYKSRSQGQLLF
CCHHHHCCCHHCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHCCCCCCCEEE
SVEKSLNLALVNGIRAIRSHIDSFGENVMRDWDLLDDIRKKWRDKIFLQFVALVPLEFWQ
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TYEGELLAQRVALNGDLLGGVIAPPFNKKKTIQSLLHLVQLANRLNCDIDLHIDESQSCP
CCCHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
AAGVKLLLEVLGRIKNEISITCSHLSSMALLREKSISNLAKEIAEKKLNVVALPLTNSWL
HHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEE
LGRNERSTSIKRPLAPIFQLQKAGVVVSVGGDNVNDAWFPFTNFDPINLMAFSMPIAHLT
ECCCCCCCHHHCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCHHHCC
PWERLGLSPFTSSAASILNLQWDGVLQKGSPADFVLLDSNSWVKALSERPKRRVVVNGEF
CHHHCCCCCCCHHHHHHEEEEECCEECCCCCCCEEEECCCHHHHHHHCCCCCEEEECHHH
LNELPKNKKSTFNNSHS
HHHCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]