Click here to switch to the map view.

The map label for this gene is 124026346

Identifier: 124026346

GI number: 124026346

Start: 1337575

End: 1339914

Strand: Direct

Name: 124026346

Synonym: NATL1_16401

Alternate gene names: NA

Gene position: 1337575-1339914 (Clockwise)

Preceding gene: 124026344

Following gene: 124026349

Centisome position: 71.73

GC content: 26.11

Gene sequence:

>2340_bases
TTGAGTGGTTTCGGGGAAAAGAAAAAAGAGAATAAAGGCTCTTCTAAAAAACTCCAAAAGCTTTCAGAAAAGGATCTGAA
AGCAAAATCAATCAATAATCATATTAAAGGGAATTTAGATGAAGCAGAGAAAGGTTATATAGCTTTTTTAAGAAATGGTT
ATTCTGATGCAGATATAATTTCAAATTATGCACTCATATGTGAAGGAAAAGGAGAAAATGAGAAAGCAATAAGATTATAC
AAAAAATGTGCTAAAAGTTTTCCAAATCATATTTACTCAAAATTAAATTTATCTTTTTTATATTATAAATTAAATCAATT
AGAAATAGCAGAAAAAATAATTGAAGAAGCAATTCAATTAAAGCCAAGCATGCCAAATGGGCATTGTATCAGAGGATTGA
TTTTAAAAGGTTTAGATAAATATGATGAGTCAAGACTATCATTTGAGAAAGCAATCGAACTAGATAAAAATTACTTTGAT
GCTTATATCAATCTAGGATTATTGAACAAAGATTCTAATAAATATAATGAAGCAGAAGAATGTTATTTAAAAGCATTAGA
AATAAATAATAAATCTGCTATCGCTCATTTGAATCTAGGCGCATGCTACAAAGAGAAACAAGATCTAGATAAAGCCATTT
TGCATACTAAGATGGCAATAGAGATAGATAATAAATTAGAAAACTGTTATTTAAATCTAGCTACAATATATAACCAAATT
GGAGATTATAAAAAATCACTCTCACTTACAAAAAAAGAACTTTTATTGCATAAGCATAGTGAGTTAAGTTATCAACTTAT
AAGTGAATTAATCAAAAAAGGAGAAGTATTAATCACATCGGAGAAAGATAATAGAGAATTACTTAAAAATTTATTAAATA
GAAAAGATATATCTCATCGAGAACTATTTGGGAATATAAACAGCCTTATCTCGAAAGAAATATTAGAAGAATTATCTATT
TTAGAATCGAAGTTGTATGAAAACAATAAATTTAATATTTTAATTAAGGACAAGGAATTAGTAAAAGCACTTTCTTTACT
AATATTTTGCTCTCCATTATGGGAAAAGGTTTTAGGAAATATACGTAAGAATATTCTATTAAACTATTCAGATAAAGATA
AAATAAGTAATAGTATTTTCAACTTTATAATAGGGCTTGGATCACAATGTTTCTTAAATGAGTATGTCTATTACATATCT
ACAGAAGAAAAGGATAAACTAAAAGAACTTAAAAAGATAATCAATAATAATAAAAATCAAGACTATACATTAGCAATAAT
TTCTTGCTACCAATCTCTATCTTCAATAAATGATGAAATAATTAATTTAAATACTTATATACCAAATAAAAAAGAATTAA
ATAATCTTCTTAATTTACAATTTAAAGAGTTAAATGCTGAAAAAATGATTTCAAAAGGAATTAAAAAGATAGGAAATATA
AAAGATTCAACATCTAAAGAAGTTAAAAACCAGTATGAATTAAACCCATATCCTAGATGGAGATACAATTCATATACTAA
AGAAAACAAACTGAACTTTTTTTCAGTTATTAATTCAGAAATTTCACCGAATACAATTAAACCTAATTCAGCTCAATTAA
CAAATAAAAAAATAAATATTCTTATAGCAGGTTGTGGAACGGGTATTCAAATAATTGAAGCATCTCGGTATAGTAATTGT
GAAATAACAGCCATCGATCTAAGCAATTCAAGTATCTCATATGCAAAGAGAAAGGTCGATGAATATGGATTGAAAAATAT
CAATTTTATAGAAATGGATTTACTTGAATTGACATCGCTAAATAAAAGATTTGATTTAATAGAATGTTCAGGTGTTCTTC
ACCATATGAATGAGCCTATTAAGGGATTATCAAATCTATTTGAAGTATTAGAACCAGAAGGCTTTTTAAAGTTAGGTTTG
TACAGCAAGTATGCAAGAGAAGAAATCCTAAAAGCAAGAAAACTAATCAAAGAAAAAGATATTAAACCAAACATTGATGG
AATAAGAAACTTCCGAAATGATCTTCTGAATGGAGAAATTAAAGAGGTAAATGAGATAAGTAATTGGTCAGATTTCTACT
CAACTTCAATGTGTAGAGATCTTTGCTTTCATATCCATGAAAACTGTTACACGCTAATCGAAATTAAAAACATGTTAAAA
GTATCTAATCTGGAATTCCTAGGTTTTACTCTTTCAAAAGAAATTAGAGATAAGTATCAGATAGATAATAAAGATAAAGA
CTCTTTAAAAAATTTAGAATTATGGGATAAATTTGAAAAATTAAATCCTAAATCTTTTAGAGAAATGTATCAATTCTGGT
CTAGGAAATCAACTAAATAG

Upstream 100 bases:

>100_bases
TAAATTACTATTAACTACAGTTTGGAAACTATAGATTTATTAAGCTAAAATAATTAGATTATTAACTTTTTGTATAATCA
TATTAATTAAATAAAAATCA

Downstream 100 bases:

>100_bases
TTGCTCTTCCAATCCTGGAATAAACATTTTACATAGGCTAAAAATAAATAATATTGCGAGAACATTACCAAGCATTGCTA
TTGCAAAGCGAATTCTTAGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 779; Mature: 778

Protein sequence:

>779_residues
MSGFGEKKKENKGSSKKLQKLSEKDLKAKSINNHIKGNLDEAEKGYIAFLRNGYSDADIISNYALICEGKGENEKAIRLY
KKCAKSFPNHIYSKLNLSFLYYKLNQLEIAEKIIEEAIQLKPSMPNGHCIRGLILKGLDKYDESRLSFEKAIELDKNYFD
AYINLGLLNKDSNKYNEAEECYLKALEINNKSAIAHLNLGACYKEKQDLDKAILHTKMAIEIDNKLENCYLNLATIYNQI
GDYKKSLSLTKKELLLHKHSELSYQLISELIKKGEVLITSEKDNRELLKNLLNRKDISHRELFGNINSLISKEILEELSI
LESKLYENNKFNILIKDKELVKALSLLIFCSPLWEKVLGNIRKNILLNYSDKDKISNSIFNFIIGLGSQCFLNEYVYYIS
TEEKDKLKELKKIINNNKNQDYTLAIISCYQSLSSINDEIINLNTYIPNKKELNNLLNLQFKELNAEKMISKGIKKIGNI
KDSTSKEVKNQYELNPYPRWRYNSYTKENKLNFFSVINSEISPNTIKPNSAQLTNKKINILIAGCGTGIQIIEASRYSNC
EITAIDLSNSSISYAKRKVDEYGLKNINFIEMDLLELTSLNKRFDLIECSGVLHHMNEPIKGLSNLFEVLEPEGFLKLGL
YSKYAREEILKARKLIKEKDIKPNIDGIRNFRNDLLNGEIKEVNEISNWSDFYSTSMCRDLCFHIHENCYTLIEIKNMLK
VSNLEFLGFTLSKEIRDKYQIDNKDKDSLKNLELWDKFEKLNPKSFREMYQFWSRKSTK

Sequences:

>Translated_779_residues
MSGFGEKKKENKGSSKKLQKLSEKDLKAKSINNHIKGNLDEAEKGYIAFLRNGYSDADIISNYALICEGKGENEKAIRLY
KKCAKSFPNHIYSKLNLSFLYYKLNQLEIAEKIIEEAIQLKPSMPNGHCIRGLILKGLDKYDESRLSFEKAIELDKNYFD
AYINLGLLNKDSNKYNEAEECYLKALEINNKSAIAHLNLGACYKEKQDLDKAILHTKMAIEIDNKLENCYLNLATIYNQI
GDYKKSLSLTKKELLLHKHSELSYQLISELIKKGEVLITSEKDNRELLKNLLNRKDISHRELFGNINSLISKEILEELSI
LESKLYENNKFNILIKDKELVKALSLLIFCSPLWEKVLGNIRKNILLNYSDKDKISNSIFNFIIGLGSQCFLNEYVYYIS
TEEKDKLKELKKIINNNKNQDYTLAIISCYQSLSSINDEIINLNTYIPNKKELNNLLNLQFKELNAEKMISKGIKKIGNI
KDSTSKEVKNQYELNPYPRWRYNSYTKENKLNFFSVINSEISPNTIKPNSAQLTNKKINILIAGCGTGIQIIEASRYSNC
EITAIDLSNSSISYAKRKVDEYGLKNINFIEMDLLELTSLNKRFDLIECSGVLHHMNEPIKGLSNLFEVLEPEGFLKLGL
YSKYAREEILKARKLIKEKDIKPNIDGIRNFRNDLLNGEIKEVNEISNWSDFYSTSMCRDLCFHIHENCYTLIEIKNMLK
VSNLEFLGFTLSKEIRDKYQIDNKDKDSLKNLELWDKFEKLNPKSFREMYQFWSRKSTK
>Mature_778_residues
SGFGEKKKENKGSSKKLQKLSEKDLKAKSINNHIKGNLDEAEKGYIAFLRNGYSDADIISNYALICEGKGENEKAIRLYK
KCAKSFPNHIYSKLNLSFLYYKLNQLEIAEKIIEEAIQLKPSMPNGHCIRGLILKGLDKYDESRLSFEKAIELDKNYFDA
YINLGLLNKDSNKYNEAEECYLKALEINNKSAIAHLNLGACYKEKQDLDKAILHTKMAIEIDNKLENCYLNLATIYNQIG
DYKKSLSLTKKELLLHKHSELSYQLISELIKKGEVLITSEKDNRELLKNLLNRKDISHRELFGNINSLISKEILEELSIL
ESKLYENNKFNILIKDKELVKALSLLIFCSPLWEKVLGNIRKNILLNYSDKDKISNSIFNFIIGLGSQCFLNEYVYYIST
EEKDKLKELKKIINNNKNQDYTLAIISCYQSLSSINDEIINLNTYIPNKKELNNLLNLQFKELNAEKMISKGIKKIGNIK
DSTSKEVKNQYELNPYPRWRYNSYTKENKLNFFSVINSEISPNTIKPNSAQLTNKKINILIAGCGTGIQIIEASRYSNCE
ITAIDLSNSSISYAKRKVDEYGLKNINFIEMDLLELTSLNKRFDLIECSGVLHHMNEPIKGLSNLFEVLEPEGFLKLGLY
SKYAREEILKARKLIKEKDIKPNIDGIRNFRNDLLNGEIKEVNEISNWSDFYSTSMCRDLCFHIHENCYTLIEIKNMLKV
SNLEFLGFTLSKEIRDKYQIDNKDKDSLKNLELWDKFEKLNPKSFREMYQFWSRKSTK

Specific function: Unknown

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv2067c [H]

Homologues:

Organism=Homo sapiens, GI32307148, Length=211, Percent_Identity=29.3838862559242, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI32307150, Length=211, Percent_Identity=29.3838862559242, Blast_Score=84, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI115532690, Length=175, Percent_Identity=29.7142857142857, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115532692, Length=175, Percent_Identity=29.7142857142857, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17647755, Length=283, Percent_Identity=26.8551236749117, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24585827, Length=283, Percent_Identity=26.8551236749117, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24585829, Length=283, Percent_Identity=26.8551236749117, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24647123, Length=208, Percent_Identity=25.9615384615385, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161076610, Length=196, Percent_Identity=26.0204081632653, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI19920486, Length=196, Percent_Identity=26.0204081632653, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 90270; Mature: 90139

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGFGEKKKENKGSSKKLQKLSEKDLKAKSINNHIKGNLDEAEKGYIAFLRNGYSDADII
CCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCHHHH
SNYALICEGKGENEKAIRLYKKCAKSFPNHIYSKLNLSFLYYKLNQLEIAEKIIEEAIQL
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHC
KPSMPNGHCIRGLILKGLDKYDESRLSFEKAIELDKNYFDAYINLGLLNKDSNKYNEAEE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHH
CYLKALEINNKSAIAHLNLGACYKEKQDLDKAILHTKMAIEIDNKLENCYLNLATIYNQI
HHHHHHEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHH
GDYKKSLSLTKKELLLHKHSELSYQLISELIKKGEVLITSEKDNRELLKNLLNRKDISHR
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCHH
ELFGNINSLISKEILEELSILESKLYENNKFNILIKDKELVKALSLLIFCSPLWEKVLGN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
IRKNILLNYSDKDKISNSIFNFIIGLGSQCFLNEYVYYISTEEKDKLKELKKIINNNKNQ
HHHHEEECCCCHHHHHHHHHHHHHHCCCHHHHHCEEEEEECCCHHHHHHHHHHHCCCCCC
DYTLAIISCYQSLSSINDEIINLNTYIPNKKELNNLLNLQFKELNAEKMISKGIKKIGNI
CHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCHHHHCCHHHHHHHHHHHHCCC
KDSTSKEVKNQYELNPYPRWRYNSYTKENKLNFFSVINSEISPNTIKPNSAQLTNKKINI
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEE
LIAGCGTGIQIIEASRYSNCEITAIDLSNSSISYAKRKVDEYGLKNINFIEMDLLELTSL
EEEECCCCEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHC
NKRFDLIECSGVLHHMNEPIKGLSNLFEVLEPEGFLKLGLYSKYAREEILKARKLIKEKD
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCC
IKPNIDGIRNFRNDLLNGEIKEVNEISNWSDFYSTSMCRDLCFHIHENCYTLIEIKNMLK
CCCCHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSNLEFLGFTLSKEIRDKYQIDNKDKDSLKNLELWDKFEKLNPKSFREMYQFWSRKSTK
HCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SGFGEKKKENKGSSKKLQKLSEKDLKAKSINNHIKGNLDEAEKGYIAFLRNGYSDADII
CCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCHHHH
SNYALICEGKGENEKAIRLYKKCAKSFPNHIYSKLNLSFLYYKLNQLEIAEKIIEEAIQL
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHC
KPSMPNGHCIRGLILKGLDKYDESRLSFEKAIELDKNYFDAYINLGLLNKDSNKYNEAEE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHH
CYLKALEINNKSAIAHLNLGACYKEKQDLDKAILHTKMAIEIDNKLENCYLNLATIYNQI
HHHHHHEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHH
GDYKKSLSLTKKELLLHKHSELSYQLISELIKKGEVLITSEKDNRELLKNLLNRKDISHR
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCHH
ELFGNINSLISKEILEELSILESKLYENNKFNILIKDKELVKALSLLIFCSPLWEKVLGN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
IRKNILLNYSDKDKISNSIFNFIIGLGSQCFLNEYVYYISTEEKDKLKELKKIINNNKNQ
HHHHEEECCCCHHHHHHHHHHHHHHCCCHHHHHCEEEEEECCCHHHHHHHHHHHCCCCCC
DYTLAIISCYQSLSSINDEIINLNTYIPNKKELNNLLNLQFKELNAEKMISKGIKKIGNI
CHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCHHHHCCHHHHHHHHHHHHCCC
KDSTSKEVKNQYELNPYPRWRYNSYTKENKLNFFSVINSEISPNTIKPNSAQLTNKKINI
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEE
LIAGCGTGIQIIEASRYSNCEITAIDLSNSSISYAKRKVDEYGLKNINFIEMDLLELTSL
EEEECCCCEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHC
NKRFDLIECSGVLHHMNEPIKGLSNLFEVLEPEGFLKLGLYSKYAREEILKARKLIKEKD
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCC
IKPNIDGIRNFRNDLLNGEIKEVNEISNWSDFYSTSMCRDLCFHIHENCYTLIEIKNMLK
CCCCHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSNLEFLGFTLSKEIRDKYQIDNKDKDSLKNLELWDKFEKLNPKSFREMYQFWSRKSTK
HCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3041005; 1901865 [H]