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The map label for this gene is pip [H]

Identifier: 124025970

GI number: 124025970

Start: 1084267

End: 1085217

Strand: Reverse

Name: pip [H]

Synonym: NATL1_12631

Alternate gene names: 124025970

Gene position: 1085217-1084267 (Counterclockwise)

Preceding gene: 124025974

Following gene: 124025969

Centisome position: 58.2

GC content: 34.28

Gene sequence:

>951_bases
ATGTTATTTCCGGAAATAGAACCTAACGAAAAAGGGATGTTAAATGTCAGTCCACTACATTCCATCTATTGGGAAAGAAG
TGGTAATCCCTATGGTTTGTCTGTCTTAATTATTCATGGCGGCCCAGGAGGAGGTAGCAGTCCTTCTTATCGAAGATATT
TTGATCCAAAAAAATTTAATATTGTTCAATTTGATCAAAGAGGATGTGGTAGATCTACTCCACATTCTGAGTTAGAGGAG
AACACCACTCATCATTTAATTGAAGATATTGAAAAGATAAGACAGCTCTTGAAAATTGAGTCATGGCATGTTTTTGGAGG
CTCATGGGGGTCAACCTTAAGCTTGATTTATGCCATACAACACACAGAAAAAGTTTTAAGTCTTACTCTTAGGGGGATAT
TTTTATGCAGACAACACGAATTAACTTGGTTCTATCAAAAAGGTGCTAGTGAGATTTTCCCTGAAGAATTCGATCTTTAT
CAATCTGTCATTCCGCTAAATGAGAGAGGGAATTTGATTAATGCTTTTCATAAGAGATTAACAAGTCAAGATAGGTCTGA
GAGAACTCAAGCGGCACATGCTTGGACGAGATGGGAAATGTCAACTAGCTATCTCAAGCCAAAAGAATTATCAATTAATA
AAGCTACTAATGATAATTTCTCAGACTCTTTTGCGCGTATAGAATGTCATTATTTTATTAATAATATTTTTTTAGAGGAG
AACTATATTCTAAAAAATATTAATAAGCTAAAAGGTATTCCTGTTTCGATTGTTCAGGGAAGATATGACGTTGTTTGTCC
AATGAGAAGTGCATGGGATCTTAATAAAGCATTGCCCACTTCTAAACTTTATGTAATCGATAATGCAGGACATTCAATGA
AAGAAATTGGAATTTCTAAAAGATTAATTGAATTGACAAATGAGTTAGCCAATTCTTTCTCTAATCTCTAA

Upstream 100 bases:

>100_bases
TAATCAATTCCTTATTGATAATCCTTTATAGCTAATTTTGTTATGTATGCTTGAGTTGAATGACATAGCTTAAAAGTAAA
AGACGAGTATTTAATTAAAA

Downstream 100 bases:

>100_bases
GCTTTAGTAGCTGTTATTAGATCTCAATAATATTTATTAAGTTTGTATGTTTTGTACTTGATTGGATGTCAATGGATTTA
TTTACCGATTGATAAAACTT

Product: hydrolases or acyltransferases

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MLFPEIEPNEKGMLNVSPLHSIYWERSGNPYGLSVLIIHGGPGGGSSPSYRRYFDPKKFNIVQFDQRGCGRSTPHSELEE
NTTHHLIEDIEKIRQLLKIESWHVFGGSWGSTLSLIYAIQHTEKVLSLTLRGIFLCRQHELTWFYQKGASEIFPEEFDLY
QSVIPLNERGNLINAFHKRLTSQDRSERTQAAHAWTRWEMSTSYLKPKELSINKATNDNFSDSFARIECHYFINNIFLEE
NYILKNINKLKGIPVSIVQGRYDVVCPMRSAWDLNKALPTSKLYVIDNAGHSMKEIGISKRLIELTNELANSFSNL

Sequences:

>Translated_316_residues
MLFPEIEPNEKGMLNVSPLHSIYWERSGNPYGLSVLIIHGGPGGGSSPSYRRYFDPKKFNIVQFDQRGCGRSTPHSELEE
NTTHHLIEDIEKIRQLLKIESWHVFGGSWGSTLSLIYAIQHTEKVLSLTLRGIFLCRQHELTWFYQKGASEIFPEEFDLY
QSVIPLNERGNLINAFHKRLTSQDRSERTQAAHAWTRWEMSTSYLKPKELSINKATNDNFSDSFARIECHYFINNIFLEE
NYILKNINKLKGIPVSIVQGRYDVVCPMRSAWDLNKALPTSKLYVIDNAGHSMKEIGISKRLIELTNELANSFSNL
>Mature_316_residues
MLFPEIEPNEKGMLNVSPLHSIYWERSGNPYGLSVLIIHGGPGGGSSPSYRRYFDPKKFNIVQFDQRGCGRSTPHSELEE
NTTHHLIEDIEKIRQLLKIESWHVFGGSWGSTLSLIYAIQHTEKVLSLTLRGIFLCRQHELTWFYQKGASEIFPEEFDLY
QSVIPLNERGNLINAFHKRLTSQDRSERTQAAHAWTRWEMSTSYLKPKELSINKATNDNFSDSFARIECHYFINNIFLEE
NYILKNINKLKGIPVSIVQGRYDVVCPMRSAWDLNKALPTSKLYVIDNAGHSMKEIGISKRLIELTNELANSFSNL

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 36369; Mature: 36369

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFPEIEPNEKGMLNVSPLHSIYWERSGNPYGLSVLIIHGGPGGGSSPSYRRYFDPKKFN
CCCCCCCCCCCCEEECCHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCE
IVQFDQRGCGRSTPHSELEENTTHHLIEDIEKIRQLLKIESWHVFGGSWGSTLSLIYAIQ
EEEECCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHH
HTEKVLSLTLRGIFLCRQHELTWFYQKGASEIFPEEFDLYQSVIPLNERGNLINAFHKRL
HHHHHHHHHHHHHHEEEECCCEEEEECCCHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHH
TSQDRSERTQAAHAWTRWEMSTSYLKPKELSINKATNDNFSDSFARIECHYFINNIFLEE
HCCHHHHHHHHHHHHHEECCHHCCCCCCCCEEECCCCCCCCCCHHEEEEEEEEEEEEECC
NYILKNINKLKGIPVSIVQGRYDVVCPMRSAWDLNKALPTSKLYVIDNAGHSMKEIGISK
CHHHHHHHHHCCCCEEEECCCEEEECCCHHHCCHHHCCCCCEEEEEECCCCHHHHHHHHH
RLIELTNELANSFSNL
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLFPEIEPNEKGMLNVSPLHSIYWERSGNPYGLSVLIIHGGPGGGSSPSYRRYFDPKKFN
CCCCCCCCCCCCEEECCHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCE
IVQFDQRGCGRSTPHSELEENTTHHLIEDIEKIRQLLKIESWHVFGGSWGSTLSLIYAIQ
EEEECCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHH
HTEKVLSLTLRGIFLCRQHELTWFYQKGASEIFPEEFDLYQSVIPLNERGNLINAFHKRL
HHHHHHHHHHHHHHEEEECCCEEEEECCCHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHH
TSQDRSERTQAAHAWTRWEMSTSYLKPKELSINKATNDNFSDSFARIECHYFINNIFLEE
HCCHHHHHHHHHHHHHEECCHHCCCCCCCCEEECCCCCCCCCCHHEEEEEEEEEEEEECC
NYILKNINKLKGIPVSIVQGRYDVVCPMRSAWDLNKALPTSKLYVIDNAGHSMKEIGISK
CHHHHHHHHHCCCCEEEECCCEEEECCCHHHCCHHHCCCCCEEEEEECCCCHHHHHHHHH
RLIELTNELANSFSNL
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA