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The map label for this gene is ruvA

Identifier: 124025644

GI number: 124025644

Start: 865706

End: 866380

Strand: Reverse

Name: ruvA

Synonym: NATL1_09371

Alternate gene names: 124025644

Gene position: 866380-865706 (Counterclockwise)

Preceding gene: 124025645

Following gene: 124025643

Centisome position: 46.46

GC content: 29.48

Gene sequence:

>675_bases
ATGATTAGCTGGTTAAAAGGCGAAAAAGTTCATACTTGGAAAATATCCTCAAGAAAAGGAGTGGTTCTAAATGTTGGTGG
TGTTGGCTATGAAATACAACTATTACCAAAACAAATAGATAAAGCTGAAGTTTTAAATGAGTTTGAATTATGGATTCATC
AAATAGATCGTGAAGATGGCACAAGCTTATATGGTTTTATAGAGGTTAATCAAAGAGATCTATTCAGAGAAATCATCAGT
GTAAATGGAATAGGCCCCCAAATAGGTATGGCTATGTTAGAGGAATTTGAAGTTCCTCAATTAGTTAATGCAATAGAAAA
TAAAGAATCTAATTTATTAACAAAAACCCAAGGCATAGGTAAAAGAATCGCAGAGAGATTAATAGTTGAGCTAAGAAATA
AACTTCAAAGGTTTACAGACAATGATAAAACAATTCATGAAAACAAAAAAGGCATAGAGGCTAATCAATTCTCCAAATAT
ATTGATGAAATATATTTAATTCTAAATTCACTTGGCTATGTAGATAATGAAATAAAAGAATCAATTAAAATAATCACAAT
CAATGAAAAAGAAAATTCTTTGTTATTGAATTCTTCATCTGCAGAAGAAAAAGCAGAGCTAATGGATAAACATCTCAAAG
AGATTCTTATGAAATTAAGTGAAAAGACTACTTGA

Upstream 100 bases:

>100_bases
GGCAATTCCTGCTGGTTTGGTAGGAGGGTCAATGGTTGGATGTCAGATTGATGGTGGTTGAGAATATTTTATATTTTCAG
AAATTTAATTAAAATAAATA

Downstream 100 bases:

>100_bases
TAGAAGGCTAGGGATTAAATTAGAATTCATGTATAAGAAAAGCTAAACAAATGTCACTTGGCACAGAAGAGAAACAAAAT
CTAATCAACACACATCAAGT

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MISWLKGEKVHTWKISSRKGVVLNVGGVGYEIQLLPKQIDKAEVLNEFELWIHQIDREDGTSLYGFIEVNQRDLFREIIS
VNGIGPQIGMAMLEEFEVPQLVNAIENKESNLLTKTQGIGKRIAERLIVELRNKLQRFTDNDKTIHENKKGIEANQFSKY
IDEIYLILNSLGYVDNEIKESIKIITINEKENSLLLNSSSAEEKAELMDKHLKEILMKLSEKTT

Sequences:

>Translated_224_residues
MISWLKGEKVHTWKISSRKGVVLNVGGVGYEIQLLPKQIDKAEVLNEFELWIHQIDREDGTSLYGFIEVNQRDLFREIIS
VNGIGPQIGMAMLEEFEVPQLVNAIENKESNLLTKTQGIGKRIAERLIVELRNKLQRFTDNDKTIHENKKGIEANQFSKY
IDEIYLILNSLGYVDNEIKESIKIITINEKENSLLLNSSSAEEKAELMDKHLKEILMKLSEKTT
>Mature_224_residues
MISWLKGEKVHTWKISSRKGVVLNVGGVGYEIQLLPKQIDKAEVLNEFELWIHQIDREDGTSLYGFIEVNQRDLFREIIS
VNGIGPQIGMAMLEEFEVPQLVNAIENKESNLLTKTQGIGKRIAERLIVELRNKLQRFTDNDKTIHENKKGIEANQFSKY
IDEIYLILNSLGYVDNEIKESIKIITINEKENSLLLNSSSAEEKAELMDKHLKEILMKLSEKTT

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=152, Percent_Identity=36.8421052631579, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_PROM1 (A2C1Y5)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001014760.1
- ProteinModelPortal:   A2C1Y5
- SMR:   A2C1Y5
- STRING:   A2C1Y5
- GeneID:   4779225
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_09371
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   IATKEVK
- ProtClustDB:   PRK00116
- BioCyc:   PMAR167555:NATL1_09371-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like

EC number: =3.6.4.12

Molecular weight: Translated: 25728; Mature: 25728

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISWLKGEKVHTWKISSRKGVVLNVGGVGYEIQLLPKQIDKAEVLNEFELWIHQIDREDG
CCCCCCCCEEEEEEECCCCCEEEEECCCCEEEEECHHHCCHHHHHHHHHHHHHHHCCCCC
TSLYGFIEVNQRDLFREIISVNGIGPQIGMAMLEEFEVPQLVNAIENKESNLLTKTQGIG
CEEEEEEEECHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHH
KRIAERLIVELRNKLQRFTDNDKTIHENKKGIEANQFSKYIDEIYLILNSLGYVDNEIKE
HHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHC
SIKIITINEKENSLLLNSSSAEEKAELMDKHLKEILMKLSEKTT
CEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MISWLKGEKVHTWKISSRKGVVLNVGGVGYEIQLLPKQIDKAEVLNEFELWIHQIDREDG
CCCCCCCCEEEEEEECCCCCEEEEECCCCEEEEECHHHCCHHHHHHHHHHHHHHHCCCCC
TSLYGFIEVNQRDLFREIISVNGIGPQIGMAMLEEFEVPQLVNAIENKESNLLTKTQGIG
CEEEEEEEECHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHH
KRIAERLIVELRNKLQRFTDNDKTIHENKKGIEANQFSKYIDEIYLILNSLGYVDNEIKE
HHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHC
SIKIITINEKENSLLLNSSSAEEKAELMDKHLKEILMKLSEKTT
CEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA