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The map label for this gene is mqo [H]

Identifier: 124025185

GI number: 124025185

Start: 430432

End: 431958

Strand: Direct

Name: mqo [H]

Synonym: NATL1_04721

Alternate gene names: 124025185

Gene position: 430432-431958 (Clockwise)

Preceding gene: 124025183

Following gene: 124025187

Centisome position: 23.08

GC content: 36.41

Gene sequence:

>1527_bases
TTGCAGGATAGTCTGTATGTAATCTTGATAAAGATTTTGTTTAATACCCCTACTCCAGATTCAGAAAATACTTATGACGC
AATATTAGTAGGTGCAGGAATCATGAGCTCCACTCTTGCAGTACTTCTGCATGAGCTTGAGCCAGATCTACGGTTGTTGG
TTGTTGAAAAATTATCTTCTGCTGGCTTGGAAAGTAGCTGCGCTAAGAATAATGCTGGAACAGGACATGCTGCTAACTGT
GAGCTTAATTACACTCCAATCCAAGAGGATGGCCATCTTAGTACTAACAAAGCTTTTGAAATAAATAAATCCTTTGAGCA
AAGCTTAGAGTTTTGGGCATCTTTAGCAGAAAAAGGGAAATTGATACCAAAAACTTTTTTAAATAAGTTGCCACACATCA
GCCTTGTCTTTGGAGATGAGGATATTTCTTTGCTTAAAAAAAGGTTTTCTAAACTTAGTTCTCATGCCGCTTTTGCTGAA
ATGGAATTCACCATGGACCATGGTGAATTAAAAGATTGGGTCCCATTGATTATGGATGGTAGGCAACATAGTGAGAAGAT
TGCCGCGACAAGAATTAAAAGAGGTACTGATATTGATTTTGGCAATTTAACTCGCTCATATATCAATCAAATTGAAGGAG
CAAAATCTATTGATATTAACTACTCTACAAATGTTGAAAATCTTCAACAAGATAGCGAAGGAGATTGGTATTTATCTTTA
GAAGGAGCCAAAAACAATAGAATTGTTAGATCAAAGTTTGTTTTCCTGGGGGCAGGTGGAGGAGCTTTATCCCTTTTGCA
AAAATCGAGAATTCCAGAAGGCTTGTTATATGCAGGATTCCCTGTTAGCGGCAAGTGGTTGATTTGTGATGAGGAGAAAT
CAACAAAAACACATAATGCAAAGGTTTATGGAAAGGCAGCAGTTGGAGCCCCGCCAATGTCAGTCCCGCACTTAGATACA
AGATGGATAGATAAAAAAAAATCTCTTTTGTTTGGTCCTTTCGCAGGATTTAGTTCAAATTTTTTAAAATACGGATCAAA
GTTGGATTTGTTTAGATCAATCAAAACAACTAATCTTTTCTCAATGTTGCAAGCAGGATTAGACAATATAGACCTAGGAA
AATACTTGTTAAATCAATTAATACAAACAAATGAGGATCGAATAGATACTTTAAAAAGATTTCTTCCACAGGTTTCACCT
AATGATTGGAAGCTTTCAACTGCAGGACAGCGTGTTCAAATAATTAAACAAACCTCTAAAGGTGGTGTTTTAAAAATGGG
GACAGAAGTGGTTACTTCATCAGATGGATCTTTAGCTGCTTTGCTTGGTGCTTCTCCGGGCGCAAGCACAGCAGTAACAA
TCATGATTGAAGTTCTAAACCGCTGCTGGCTGGAAAAAATGAAATCAAGTAAGTGGAAAAATAAAATGTTAGAGCTTTTC
CCCAGTATTGGTACAGATATTAATTCAGATCAAGAAGCTCTTTTGGCAATTCGAAAAAGAAACGATTTCTTACTTAAATT
AATTTAA

Upstream 100 bases:

>100_bases
CTTAATTCATCAAGAACCTTTTCAACGTTTTCTGTCGTCAGTGCAAGAGTTTCGTCGCTCATTTCGATTTACTTAATTTA
ATTTTGCTTAGCTTAGTTAA

Downstream 100 bases:

>100_bases
AACTTTAGTACTGGTGAGCTATATTTAATTTTTATTCAGAGTTGAATTGATAAATGAAGATCTTGCTCCTTTAATTGCTT
TCGTATGACTAATGTGCCCA

Product: malate:quinone oxidoreductase

Products: NA

Alternate protein names: MQO; Malate dehydrogenase [quinone] [H]

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MQDSLYVILIKILFNTPTPDSENTYDAILVGAGIMSSTLAVLLHELEPDLRLLVVEKLSSAGLESSCAKNNAGTGHAANC
ELNYTPIQEDGHLSTNKAFEINKSFEQSLEFWASLAEKGKLIPKTFLNKLPHISLVFGDEDISLLKKRFSKLSSHAAFAE
MEFTMDHGELKDWVPLIMDGRQHSEKIAATRIKRGTDIDFGNLTRSYINQIEGAKSIDINYSTNVENLQQDSEGDWYLSL
EGAKNNRIVRSKFVFLGAGGGALSLLQKSRIPEGLLYAGFPVSGKWLICDEEKSTKTHNAKVYGKAAVGAPPMSVPHLDT
RWIDKKKSLLFGPFAGFSSNFLKYGSKLDLFRSIKTTNLFSMLQAGLDNIDLGKYLLNQLIQTNEDRIDTLKRFLPQVSP
NDWKLSTAGQRVQIIKQTSKGGVLKMGTEVVTSSDGSLAALLGASPGASTAVTIMIEVLNRCWLEKMKSSKWKNKMLELF
PSIGTDINSDQEALLAIRKRNDFLLKLI

Sequences:

>Translated_508_residues
MQDSLYVILIKILFNTPTPDSENTYDAILVGAGIMSSTLAVLLHELEPDLRLLVVEKLSSAGLESSCAKNNAGTGHAANC
ELNYTPIQEDGHLSTNKAFEINKSFEQSLEFWASLAEKGKLIPKTFLNKLPHISLVFGDEDISLLKKRFSKLSSHAAFAE
MEFTMDHGELKDWVPLIMDGRQHSEKIAATRIKRGTDIDFGNLTRSYINQIEGAKSIDINYSTNVENLQQDSEGDWYLSL
EGAKNNRIVRSKFVFLGAGGGALSLLQKSRIPEGLLYAGFPVSGKWLICDEEKSTKTHNAKVYGKAAVGAPPMSVPHLDT
RWIDKKKSLLFGPFAGFSSNFLKYGSKLDLFRSIKTTNLFSMLQAGLDNIDLGKYLLNQLIQTNEDRIDTLKRFLPQVSP
NDWKLSTAGQRVQIIKQTSKGGVLKMGTEVVTSSDGSLAALLGASPGASTAVTIMIEVLNRCWLEKMKSSKWKNKMLELF
PSIGTDINSDQEALLAIRKRNDFLLKLI
>Mature_508_residues
MQDSLYVILIKILFNTPTPDSENTYDAILVGAGIMSSTLAVLLHELEPDLRLLVVEKLSSAGLESSCAKNNAGTGHAANC
ELNYTPIQEDGHLSTNKAFEINKSFEQSLEFWASLAEKGKLIPKTFLNKLPHISLVFGDEDISLLKKRFSKLSSHAAFAE
MEFTMDHGELKDWVPLIMDGRQHSEKIAATRIKRGTDIDFGNLTRSYINQIEGAKSIDINYSTNVENLQQDSEGDWYLSL
EGAKNNRIVRSKFVFLGAGGGALSLLQKSRIPEGLLYAGFPVSGKWLICDEEKSTKTHNAKVYGKAAVGAPPMSVPHLDT
RWIDKKKSLLFGPFAGFSSNFLKYGSKLDLFRSIKTTNLFSMLQAGLDNIDLGKYLLNQLIQTNEDRIDTLKRFLPQVSP
NDWKLSTAGQRVQIIKQTSKGGVLKMGTEVVTSSDGSLAALLGASPGASTAVTIMIEVLNRCWLEKMKSSKWKNKMLELF
PSIGTDINSDQEALLAIRKRNDFLLKLI

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0579

COG function: function code R; Predicted dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MQO family [H]

Homologues:

Organism=Escherichia coli, GI1788539, Length=476, Percent_Identity=46.6386554621849, Blast_Score=465, Evalue=1e-132,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006231 [H]

Pfam domain/function: PF06039 Mqo [H]

EC number: =1.1.5.4 [H]

Molecular weight: Translated: 56202; Mature: 56202

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDSLYVILIKILFNTPTPDSENTYDAILVGAGIMSSTLAVLLHELEPDLRLLVVEKLSS
CCCCHHHHEEEHHHCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHCCCCCEEHHHHHHHH
AGLESSCAKNNAGTGHAANCELNYTPIQEDGHLSTNKAFEINKSFEQSLEFWASLAEKGK
CCCCHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCC
LIPKTFLNKLPHISLVFGDEDISLLKKRFSKLSSHAAFAEMEFTMDHGELKDWVPLIMDG
CCHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHCC
RQHSEKIAATRIKRGTDIDFGNLTRSYINQIEGAKSIDINYSTNVENLQQDSEGDWYLSL
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCCCCEEEEE
EGAKNNRIVRSKFVFLGAGGGALSLLQKSRIPEGLLYAGFPVSGKWLICDEEKSTKTHNA
ECCCCCCEEEEEEEEEECCCHHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCCCCCCCC
KVYGKAAVGAPPMSVPHLDTRWIDKKKSLLFGPFAGFSSNFLKYGSKLDLFRSIKTTNLF
EEEEEEECCCCCCCCCCCCHHHHCCCCCEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHH
SMLQAGLDNIDLGKYLLNQLIQTNEDRIDTLKRFLPQVSPNDWKLSTAGQRVQIIKQTSK
HHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEECCCCCEEEEEEECCC
GGVLKMGTEVVTSSDGSLAALLGASPGASTAVTIMIEVLNRCWLEKMKSSKWKNKMLELF
CCEEEECCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PSIGTDINSDQEALLAIRKRNDFLLKLI
HHHCCCCCCCHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MQDSLYVILIKILFNTPTPDSENTYDAILVGAGIMSSTLAVLLHELEPDLRLLVVEKLSS
CCCCHHHHEEEHHHCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHCCCCCEEHHHHHHHH
AGLESSCAKNNAGTGHAANCELNYTPIQEDGHLSTNKAFEINKSFEQSLEFWASLAEKGK
CCCCHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCC
LIPKTFLNKLPHISLVFGDEDISLLKKRFSKLSSHAAFAEMEFTMDHGELKDWVPLIMDG
CCHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHCC
RQHSEKIAATRIKRGTDIDFGNLTRSYINQIEGAKSIDINYSTNVENLQQDSEGDWYLSL
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCCCCEEEEE
EGAKNNRIVRSKFVFLGAGGGALSLLQKSRIPEGLLYAGFPVSGKWLICDEEKSTKTHNA
ECCCCCCEEEEEEEEEECCCHHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCCCCCCCC
KVYGKAAVGAPPMSVPHLDTRWIDKKKSLLFGPFAGFSSNFLKYGSKLDLFRSIKTTNLF
EEEEEEECCCCCCCCCCCCHHHHCCCCCEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHH
SMLQAGLDNIDLGKYLLNQLIQTNEDRIDTLKRFLPQVSPNDWKLSTAGQRVQIIKQTSK
HHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEECCCCCEEEEEEECCC
GGVLKMGTEVVTSSDGSLAALLGASPGASTAVTIMIEVLNRCWLEKMKSSKWKNKMLELF
CCEEEECCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PSIGTDINSDQEALLAIRKRNDFLLKLI
HHHCCCCCCCHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA