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The map label for this gene is glmM [H]

Identifier: 124025071

GI number: 124025071

Start: 330652

End: 332112

Strand: Direct

Name: glmM [H]

Synonym: NATL1_03581

Alternate gene names: 124025071

Gene position: 330652-332112 (Clockwise)

Preceding gene: 124025069

Following gene: 124025072

Centisome position: 17.73

GC content: 40.04

Gene sequence:

>1461_bases
ATGAAAAAGAAAAAGTTGAATCTCACTAAGGAGAGAATTTCTTTCGGAACAGATGGATGGAGAGGGATATTAGGAGTTGA
GTTCACCTTGGAAAGATTACTTAAAGTTGCAGCAGCAGCAGCTCAAGAGCTTGATTATGTGGAAGAAAAAAATAATAATA
AAATAATCATTGGTTATGACCGACGATTCCTAGCAGAGGAGATGGCTGAGGCGGTCGCATCTGCAGTGAGAGGAGTTGAT
TTAGTCCCTTTGTTGGCTTCTTCCGCGCTGCCAACTCCCTCTTGTAGCTGGGGGATAGTTGAAGAAAATGCACTTGGTGC
ACTAGTGATTACAGCAAGTCATAACCCATGCGAATGGTTGGGTTTGAAAATTAAAGGTCCTTTTGGAGGCTCAGTTGATA
GCTCTTTTACCGATTCCGTGCAAAAAAGATTAGATGCTGGGGGGATATCAATTCCAATCGAAGGAGTAACCGAGAAAGTT
GATTTTCGAAAACAACATCTTTTGGGGATTAGTCAGGAATTTGACATGCATTTGATTGCTGATGGCTTGAGGAAACTAGG
AGTGAAAATTTTTGTCGATCCAATGCATGGATCTGCTGCGGGCTGCATGTCTGAATTATTTGGAGTTGATAGTGAAGAGC
TTATTTATGAAATAAGAACTGAAAGAGACCCAAGCTTTGGTGGGAATCCTCCAGAACCTCTGAAGGCTTACCTATCGCAA
TTAATACAAGAAGTTCAGGATGAATCCCAGGCAGGGAAATTGTCTATGGGCCTTGTTTTTGATGGAGATGGAGATCGAAT
TGCGGCAATAGATGAAAAAGGTAGATATTGCAATACGCAGTTATTAATGCCTGTCTTGATAGATCATTTGGCAAGAGTTA
GAAATATGCCAGGTTGCGTTGTAAAAACTGTGAGTGGATCGGACTTGATGAGATTAGTTGCTGAGGATCTGGGGAGAGAA
GTGCTCGAAAAGCCAGTTGGGTTTAAATATATTGCTGAAGAAATGCTTTCAAGAGAAGTTCTTATTGGAGGAGAGGAGTC
AGGGGGAGTTGGGTTTGGACATCACTTGCCAGAACGTGATGCTTTGTTTACCGCTTTGCTTTTGATGGAGTCAATAGTTG
CTGATGGTAAATGTTTAGGTGAGAAAATAGATTCTCTTCATGCTCGTTTTGGTAAGAGTCATTTCGAACGTATTGATTTA
ACTCTCAAAGACATGGAGATGAGAAGGTCTTTGGAAGATTTTTTGAAACAGAAAACCCCATCTTCAATTGGTCATAAATC
AGTTTTAGAGGTTATTTCAACTGATGGAATAAAACTCATACTTGATAAAAGTCATTGGCTGATGTTCCGTTTCTCTGGAA
CAGAGCCTCTTTTAAGAATTTATTGTGAAGCGCCATCCAGTGCAGAAGTTACTTCAACTTTGTATTATGCAAAGCAACTT
ATAGATAATAGTTTTGGATAA

Upstream 100 bases:

>100_bases
ACTCCTTAAAAGGTGATCGTTAATTGGTTTGGATTTATTACATTTCATACTTAGAGAATAATCCGCATTTCTTTAAGAAC
AAAGTTTCTCCAATATAAAG

Downstream 100 bases:

>100_bases
TGTCCCTCTTGTAATTGCTAGTGGCAATAAGGGTAAAATTGGAGAATTTAAAAAACTTTTAGACGATTTTCCCATTGATT
TATTGACTCAACCTGTTGGT

Product: phosphotransferase superclass

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MKKKKLNLTKERISFGTDGWRGILGVEFTLERLLKVAAAAAQELDYVEEKNNNKIIIGYDRRFLAEEMAEAVASAVRGVD
LVPLLASSALPTPSCSWGIVEENALGALVITASHNPCEWLGLKIKGPFGGSVDSSFTDSVQKRLDAGGISIPIEGVTEKV
DFRKQHLLGISQEFDMHLIADGLRKLGVKIFVDPMHGSAAGCMSELFGVDSEELIYEIRTERDPSFGGNPPEPLKAYLSQ
LIQEVQDESQAGKLSMGLVFDGDGDRIAAIDEKGRYCNTQLLMPVLIDHLARVRNMPGCVVKTVSGSDLMRLVAEDLGRE
VLEKPVGFKYIAEEMLSREVLIGGEESGGVGFGHHLPERDALFTALLLMESIVADGKCLGEKIDSLHARFGKSHFERIDL
TLKDMEMRRSLEDFLKQKTPSSIGHKSVLEVISTDGIKLILDKSHWLMFRFSGTEPLLRIYCEAPSSAEVTSTLYYAKQL
IDNSFG

Sequences:

>Translated_486_residues
MKKKKLNLTKERISFGTDGWRGILGVEFTLERLLKVAAAAAQELDYVEEKNNNKIIIGYDRRFLAEEMAEAVASAVRGVD
LVPLLASSALPTPSCSWGIVEENALGALVITASHNPCEWLGLKIKGPFGGSVDSSFTDSVQKRLDAGGISIPIEGVTEKV
DFRKQHLLGISQEFDMHLIADGLRKLGVKIFVDPMHGSAAGCMSELFGVDSEELIYEIRTERDPSFGGNPPEPLKAYLSQ
LIQEVQDESQAGKLSMGLVFDGDGDRIAAIDEKGRYCNTQLLMPVLIDHLARVRNMPGCVVKTVSGSDLMRLVAEDLGRE
VLEKPVGFKYIAEEMLSREVLIGGEESGGVGFGHHLPERDALFTALLLMESIVADGKCLGEKIDSLHARFGKSHFERIDL
TLKDMEMRRSLEDFLKQKTPSSIGHKSVLEVISTDGIKLILDKSHWLMFRFSGTEPLLRIYCEAPSSAEVTSTLYYAKQL
IDNSFG
>Mature_486_residues
MKKKKLNLTKERISFGTDGWRGILGVEFTLERLLKVAAAAAQELDYVEEKNNNKIIIGYDRRFLAEEMAEAVASAVRGVD
LVPLLASSALPTPSCSWGIVEENALGALVITASHNPCEWLGLKIKGPFGGSVDSSFTDSVQKRLDAGGISIPIEGVTEKV
DFRKQHLLGISQEFDMHLIADGLRKLGVKIFVDPMHGSAAGCMSELFGVDSEELIYEIRTERDPSFGGNPPEPLKAYLSQ
LIQEVQDESQAGKLSMGLVFDGDGDRIAAIDEKGRYCNTQLLMPVLIDHLARVRNMPGCVVKTVSGSDLMRLVAEDLGRE
VLEKPVGFKYIAEEMLSREVLIGGEESGGVGFGHHLPERDALFTALLLMESIVADGKCLGEKIDSLHARFGKSHFERIDL
TLKDMEMRRSLEDFLKQKTPSSIGHKSVLEVISTDGIKLILDKSHWLMFRFSGTEPLLRIYCEAPSSAEVTSTLYYAKQL
IDNSFG

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI133922562, Length=483, Percent_Identity=23.3954451345756, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI21361621, Length=479, Percent_Identity=23.1732776617954, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI290463102, Length=481, Percent_Identity=22.6611226611227, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI290463104, Length=312, Percent_Identity=24.0384615384615, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1786904, Length=503, Percent_Identity=27.037773359841, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789566, Length=497, Percent_Identity=23.943661971831, Blast_Score=92, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17535441, Length=494, Percent_Identity=25.5060728744939, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6323752, Length=408, Percent_Identity=23.0392156862745, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6322722, Length=390, Percent_Identity=23.8461538461538, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17864244, Length=473, Percent_Identity=24.7357293868922, Blast_Score=119, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24651977, Length=425, Percent_Identity=23.7647058823529, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20129809, Length=425, Percent_Identity=23.7647058823529, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 53479; Mature: 53479

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKKLNLTKERISFGTDGWRGILGVEFTLERLLKVAAAAAQELDYVEEKNNNKIIIGYD
CCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
RRFLAEEMAEAVASAVRGVDLVPLLASSALPTPSCSWGIVEENALGALVITASHNPCEWL
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEECCCCEEEEEEECCCCCEEE
GLKIKGPFGGSVDSSFTDSVQKRLDAGGISIPIEGVTEKVDFRKQHLLGISQEFDMHLIA
EEEEECCCCCCCCCHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCHHHHH
DGLRKLGVKIFVDPMHGSAAGCMSELFGVDSEELIYEIRTERDPSFGGNPPEPLKAYLSQ
HHHHHCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
LIQEVQDESQAGKLSMGLVFDGDGDRIAAIDEKGRYCNTQLLMPVLIDHLARVRNMPGCV
HHHHHHCCHHCCCEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCE
VKTVSGSDLMRLVAEDLGREVLEKPVGFKYIAEEMLSREVLIGGEESGGVGFGHHLPERD
EEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCHH
ALFTALLLMESIVADGKCLGEKIDSLHARFGKSHFERIDLTLKDMEMRRSLEDFLKQKTP
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
SSIGHKSVLEVISTDGIKLILDKSHWLMFRFSGTEPLLRIYCEAPSSAEVTSTLYYAKQL
CCCCHHHHHHHHHCCCEEEEEECCCEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHH
IDNSFG
HHCCCC
>Mature Secondary Structure
MKKKKLNLTKERISFGTDGWRGILGVEFTLERLLKVAAAAAQELDYVEEKNNNKIIIGYD
CCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
RRFLAEEMAEAVASAVRGVDLVPLLASSALPTPSCSWGIVEENALGALVITASHNPCEWL
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEECCCCEEEEEEECCCCCEEE
GLKIKGPFGGSVDSSFTDSVQKRLDAGGISIPIEGVTEKVDFRKQHLLGISQEFDMHLIA
EEEEECCCCCCCCCHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCHHHHH
DGLRKLGVKIFVDPMHGSAAGCMSELFGVDSEELIYEIRTERDPSFGGNPPEPLKAYLSQ
HHHHHCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
LIQEVQDESQAGKLSMGLVFDGDGDRIAAIDEKGRYCNTQLLMPVLIDHLARVRNMPGCV
HHHHHHCCHHCCCEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCE
VKTVSGSDLMRLVAEDLGREVLEKPVGFKYIAEEMLSREVLIGGEESGGVGFGHHLPERD
EEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCHH
ALFTALLLMESIVADGKCLGEKIDSLHARFGKSHFERIDLTLKDMEMRRSLEDFLKQKTP
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
SSIGHKSVLEVISTDGIKLILDKSHWLMFRFSGTEPLLRIYCEAPSSAEVTSTLYYAKQL
CCCCHHHHHHHHHCCCEEEEEECCCEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHH
IDNSFG
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA