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The map label for this gene is murG

Identifier: 124024986

GI number: 124024986

Start: 252979

End: 254037

Strand: Direct

Name: murG

Synonym: NATL1_02731

Alternate gene names: 124024986

Gene position: 252979-254037 (Clockwise)

Preceding gene: 124024984

Following gene: 124024997

Centisome position: 13.57

GC content: 36.92

Gene sequence:

>1059_bases
ATGCCTCGCCTTTTAATTGCTGCAAGCGGAACGGGTGGGCACATTTATCCTGCATTATCTTTCGCCGATTCACTTTCAAA
TTCTTGGGAAATAGTGTGGCTAGGTGTGCCAAATAGGCTTGAGGTTGAACTAGTTCCAGAAAAATACAATTTAATTAAGT
TAAAAGTTGGAGGATTACAAGGAAATATTTTTAGAAAACTGTTTGATTTATGTAAATTACTCTTTGCGTCTGTTCAAGTC
TCTGTCTTATTACGTCAAAAAAAAATTAATGTTATTTTCACCACTGGTGGCTACATATCTGCTCCATGTATTCTCGGTGC
AAAAATGGCTGGCATCCCAGTTTTACTGCATGAATCTAATGCGATTCCTGGCAAAGTAACTAGGCTGTTGGGTAGGTTTT
GTGATCATGTAGCTTTAGGAATTCCATCAGCATCTGAGTATTTGCAAAGATGTAGAACAAGCTTTACAGGAACACCTGTA
AGGACAGAATTTTTATTTGAAAAGTCTCTGCCAAGTTGGGTCCCTCTTGGAGAGGGCGTATTGATTGTGGTAATGGGAGG
TAGTCAAGGAGCAATAAAAATGAATGAGATGGTAAGGAAGATTTTACCTTGCTTGATTGAGAAGGGTTGTAGAGTTGTTC
ACTTGACTGGAAAAAACGACTGCTTTTATAGAAATCGAGATCAAGAAAAAAGTCACCCTAATTTGGTTGTAAGAGACTTC
AGTGATGAAATGCCTGCCTTGCTTCGAAACGCTGATCTTGCAATTAGCAGGTCAGGCGCTGGTGCGATTTGTGAATTAAT
GGTAACCAAGACCCCTTCAATTTTAATACCTTTTCCAAGCTCTACCGATCAACATCAAGAACTTAATGCTGCTTATATGG
CCAGATTTGGAGGGGCTATAATAGTTAATCAACATGACCCAGAAAAAAACATATTGAAGAATATTGTGTCGAATTTATTG
GATTCTAATTCTCTTAGGGAAATGAAATTAAATATGAATAATCATGATTATTCATATCCTGAAAAAAAGATATTCGAAAT
AATACATTCTATTAGTTAA

Upstream 100 bases:

>100_bases
TAGAAATAAAAAACCTATTAATTTGGTTGTCAGTGAATGTCTCACGCCTACCTTTTTTACTCAATATAACTTAGCCTAAA
AAGATAGGGTTATTTAATTT

Downstream 100 bases:

>100_bases
TATAATCTTTTAGTGTATTAATAATTTGAATATTTTGTTCTCTTTTTAGAAGACTGATTCTGAACCATTTTTCATCTAAG
TTTATAAATGATCTACAGTC

Product: undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MPRLLIAASGTGGHIYPALSFADSLSNSWEIVWLGVPNRLEVELVPEKYNLIKLKVGGLQGNIFRKLFDLCKLLFASVQV
SVLLRQKKINVIFTTGGYISAPCILGAKMAGIPVLLHESNAIPGKVTRLLGRFCDHVALGIPSASEYLQRCRTSFTGTPV
RTEFLFEKSLPSWVPLGEGVLIVVMGGSQGAIKMNEMVRKILPCLIEKGCRVVHLTGKNDCFYRNRDQEKSHPNLVVRDF
SDEMPALLRNADLAISRSGAGAICELMVTKTPSILIPFPSSTDQHQELNAAYMARFGGAIIVNQHDPEKNILKNIVSNLL
DSNSLREMKLNMNNHDYSYPEKKIFEIIHSIS

Sequences:

>Translated_352_residues
MPRLLIAASGTGGHIYPALSFADSLSNSWEIVWLGVPNRLEVELVPEKYNLIKLKVGGLQGNIFRKLFDLCKLLFASVQV
SVLLRQKKINVIFTTGGYISAPCILGAKMAGIPVLLHESNAIPGKVTRLLGRFCDHVALGIPSASEYLQRCRTSFTGTPV
RTEFLFEKSLPSWVPLGEGVLIVVMGGSQGAIKMNEMVRKILPCLIEKGCRVVHLTGKNDCFYRNRDQEKSHPNLVVRDF
SDEMPALLRNADLAISRSGAGAICELMVTKTPSILIPFPSSTDQHQELNAAYMARFGGAIIVNQHDPEKNILKNIVSNLL
DSNSLREMKLNMNNHDYSYPEKKIFEIIHSIS
>Mature_351_residues
PRLLIAASGTGGHIYPALSFADSLSNSWEIVWLGVPNRLEVELVPEKYNLIKLKVGGLQGNIFRKLFDLCKLLFASVQVS
VLLRQKKINVIFTTGGYISAPCILGAKMAGIPVLLHESNAIPGKVTRLLGRFCDHVALGIPSASEYLQRCRTSFTGTPVR
TEFLFEKSLPSWVPLGEGVLIVVMGGSQGAIKMNEMVRKILPCLIEKGCRVVHLTGKNDCFYRNRDQEKSHPNLVVRDFS
DEMPALLRNADLAISRSGAGAICELMVTKTPSILIPFPSSTDQHQELNAAYMARFGGAIIVNQHDPEKNILKNIVSNLLD
SNSLREMKLNMNNHDYSYPEKKIFEIIHSIS

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=336, Percent_Identity=32.7380952380952, Blast_Score=149, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_PROM1 (A2C027)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001014102.1
- ProteinModelPortal:   A2C027
- SMR:   A2C027
- STRING:   A2C027
- GeneID:   4779926
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_02731
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   HICGKGN
- ProtClustDB:   CLSK2392204
- BioCyc:   PMAR167555:NATL1_02731-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38959; Mature: 38828

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLLIAASGTGGHIYPALSFADSLSNSWEIVWLGVPNRLEVELVPEKYNLIKLKVGGLQ
CCEEEEEECCCCCEEEHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCCEEEEEECCCC
GNIFRKLFDLCKLLFASVQVSVLLRQKKINVIFTTGGYISAPCILGAKMAGIPVLLHESN
CHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEECCCEECHHHHCCHHCCCEEEEECCC
AIPGKVTRLLGRFCDHVALGIPSASEYLQRCRTSFTGTPVRTEFLFEKSLPSWVPLGEGV
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCE
LIVVMGGSQGAIKMNEMVRKILPCLIEKGCRVVHLTGKNDCFYRNRDQEKSHPNLVVRDF
EEEEECCCCCCEEHHHHHHHHHHHHHHCCCEEEEEECCCCCEECCCCCCCCCCCEEEECC
SDEMPALLRNADLAISRSGAGAICELMVTKTPSILIPFPSSTDQHQELNAAYMARFGGAI
CCHHHHHHCCCCEEEECCCCCCEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHCCCEE
IVNQHDPEKNILKNIVSNLLDSNSLREMKLNMNNHDYSYPEKKIFEIIHSIS
EEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
PRLLIAASGTGGHIYPALSFADSLSNSWEIVWLGVPNRLEVELVPEKYNLIKLKVGGLQ
CEEEEEECCCCCEEEHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCCEEEEEECCCC
GNIFRKLFDLCKLLFASVQVSVLLRQKKINVIFTTGGYISAPCILGAKMAGIPVLLHESN
CHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEECCCEECHHHHCCHHCCCEEEEECCC
AIPGKVTRLLGRFCDHVALGIPSASEYLQRCRTSFTGTPVRTEFLFEKSLPSWVPLGEGV
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCE
LIVVMGGSQGAIKMNEMVRKILPCLIEKGCRVVHLTGKNDCFYRNRDQEKSHPNLVVRDF
EEEEECCCCCCEEHHHHHHHHHHHHHHCCCEEEEEECCCCCEECCCCCCCCCCCEEEECC
SDEMPALLRNADLAISRSGAGAICELMVTKTPSILIPFPSSTDQHQELNAAYMARFGGAI
CCHHHHHHCCCCEEEECCCCCCEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHCCCEE
IVNQHDPEKNILKNIVSNLLDSNSLREMKLNMNNHDYSYPEKKIFEIIHSIS
EEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA