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The map label for this gene is ppnK [H]

Identifier: 124024942

GI number: 124024942

Start: 213039

End: 213944

Strand: Reverse

Name: ppnK [H]

Synonym: NATL1_02291

Alternate gene names: 124024942

Gene position: 213944-213039 (Counterclockwise)

Preceding gene: 124024943

Following gene: 124024941

Centisome position: 11.47

GC content: 33.22

Gene sequence:

>906_bases
ATGACAACAAATCTGATCTGGATCTTATATAGATCAGATAGTGATACTGCATACAAAGAAACCTTAAATTGTAAAAAAAT
AATTGAAGGTTATGGGAAAAAAGTTTTATTTTCCGAAATAAGTAATGAAACCAATAACATTAATCAATTATTTTTAAAAT
CTGAGGTTTTACCAGAAATCACTATTGTTCTAGGAGGTGATGGAACAGTTTTAAGAGCCGCAAGATATTTATCCCCGAAA
AACATACCTATTTTAAGTTTTAATGTTGGAGGGAATCTAGGCTTTTTGACCCATGATCGTCAGATCTTAAAGCAAGAAAC
TTTTTGGGAAAGAGTTTCAAAAAATAGATTTAATATCCAAAAAAGAATGATGCTTGAAGCAACTGTTTTTAAAGAAAAGA
ACAAGAATGAAACCACAATTAAAAAATCATTTTTTGCGTTAAATGATTTTTATTTAAGATCTTGTACAGATGAGATTGCA
CCTACTTGCAGCCTCGCCCTTGAAATAGATGGTGAAGCTGTAGATAGATACAAGGGAGATGGACTTATCTTCTCTACTCC
AACAGGGTCCACTGCTTACTCTATGGCCGCTGGAGGGCCCATTATTCATCCTTCCTTGGATGCCATTATAGTAAGCGCGA
TTTGCCCAATGAGCTTGGCCAGTAGGCCAATAGTTGTCCCTCCTGAATCTCAATTAGTAATTAAACCTATAAGAGGTATG
AAACAAAAAATAAAGTTATGGTTAGATGGATCTAGTGGATGTCTAATTGAAGCTGAAGACACATGCTTAATAAAGAAATC
TAATCACTCAACATCAATAATAATTTTAGATGAAAATCATTCTTATTATAAGACAATTACTCAAAAGCTTCATTGGGCAA
GTAGCCTTAACGATCCTAATAAATAA

Upstream 100 bases:

>100_bases
CGAGGCTGCAGTTGGACTAGCAATACTACTTTCCTTGTATAGAAATAGAGTTACTATTGATATGGAAAGTTTTAATCTAC
TCAAATGGTAGATATTTTTA

Downstream 100 bases:

>100_bases
TAAGTTATGGGCATAGAAATAGAAAGAAGGTTTTTAGTTGAAAATAATGATTGGAAAAATCAGGTAATCCTAAGTGAAAG
TTTTAGTCAAGCCTACTTAA

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase 2 [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MTTNLIWILYRSDSDTAYKETLNCKKIIEGYGKKVLFSEISNETNNINQLFLKSEVLPEITIVLGGDGTVLRAARYLSPK
NIPILSFNVGGNLGFLTHDRQILKQETFWERVSKNRFNIQKRMMLEATVFKEKNKNETTIKKSFFALNDFYLRSCTDEIA
PTCSLALEIDGEAVDRYKGDGLIFSTPTGSTAYSMAAGGPIIHPSLDAIIVSAICPMSLASRPIVVPPESQLVIKPIRGM
KQKIKLWLDGSSGCLIEAEDTCLIKKSNHSTSIIILDENHSYYKTITQKLHWASSLNDPNK

Sequences:

>Translated_301_residues
MTTNLIWILYRSDSDTAYKETLNCKKIIEGYGKKVLFSEISNETNNINQLFLKSEVLPEITIVLGGDGTVLRAARYLSPK
NIPILSFNVGGNLGFLTHDRQILKQETFWERVSKNRFNIQKRMMLEATVFKEKNKNETTIKKSFFALNDFYLRSCTDEIA
PTCSLALEIDGEAVDRYKGDGLIFSTPTGSTAYSMAAGGPIIHPSLDAIIVSAICPMSLASRPIVVPPESQLVIKPIRGM
KQKIKLWLDGSSGCLIEAEDTCLIKKSNHSTSIIILDENHSYYKTITQKLHWASSLNDPNK
>Mature_300_residues
TTNLIWILYRSDSDTAYKETLNCKKIIEGYGKKVLFSEISNETNNINQLFLKSEVLPEITIVLGGDGTVLRAARYLSPKN
IPILSFNVGGNLGFLTHDRQILKQETFWERVSKNRFNIQKRMMLEATVFKEKNKNETTIKKSFFALNDFYLRSCTDEIAP
TCSLALEIDGEAVDRYKGDGLIFSTPTGSTAYSMAAGGPIIHPSLDAIIVSAICPMSLASRPIVVPPESQLVIKPIRGMK
QKIKLWLDGSSGCLIEAEDTCLIKKSNHSTSIIILDENHSYYKTITQKLHWASSLNDPNK

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=257, Percent_Identity=30.7392996108949, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1788968, Length=240, Percent_Identity=32.5, Blast_Score=118, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6320794, Length=299, Percent_Identity=31.7725752508361, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6325068, Length=199, Percent_Identity=35.678391959799, Blast_Score=105, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6322509, Length=251, Percent_Identity=29.8804780876494, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28573828, Length=251, Percent_Identity=30.2788844621514, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573830, Length=251, Percent_Identity=30.2788844621514, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573832, Length=251, Percent_Identity=30.2788844621514, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI161077047, Length=251, Percent_Identity=30.2788844621514, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573826, Length=251, Percent_Identity=30.2788844621514, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI20129957, Length=274, Percent_Identity=27.3722627737226, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24653424, Length=274, Percent_Identity=27.3722627737226, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24653422, Length=274, Percent_Identity=27.3722627737226, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281363323, Length=274, Percent_Identity=27.3722627737226, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281363321, Length=274, Percent_Identity=27.3722627737226, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 33687; Mature: 33556

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNLIWILYRSDSDTAYKETLNCKKIIEGYGKKVLFSEISNETNNINQLFLKSEVLPEI
CCCEEEEEEEECCCCHHHHHHCCHHHHHHHCCCEEEHHHHCCCCCCHHHHHHHHCCCCEE
TIVLGGDGTVLRAARYLSPKNIPILSFNVGGNLGFLTHDRQILKQETFWERVSKNRFNIQ
EEEECCCCHHHHHHHHCCCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHCCHHHHH
KRMMLEATVFKEKNKNETTIKKSFFALNDFYLRSCTDEIAPTCSLALEIDGEAVDRYKGD
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHCCCC
GLIFSTPTGSTAYSMAAGGPIIHPSLDAIIVSAICPMSLASRPIVVPPESQLVIKPIRGM
EEEEECCCCCCEEECCCCCCEECCCHHHHHHHHHCCHHHCCCCEEECCCCCEEEECHHCC
KQKIKLWLDGSSGCLIEAEDTCLIKKSNHSTSIIILDENHSYYKTITQKLHWASSLNDPN
CEEEEEEEECCCCEEEEECCEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCC
K
C
>Mature Secondary Structure 
TTNLIWILYRSDSDTAYKETLNCKKIIEGYGKKVLFSEISNETNNINQLFLKSEVLPEI
CCEEEEEEEECCCCHHHHHHCCHHHHHHHCCCEEEHHHHCCCCCCHHHHHHHHCCCCEE
TIVLGGDGTVLRAARYLSPKNIPILSFNVGGNLGFLTHDRQILKQETFWERVSKNRFNIQ
EEEECCCCHHHHHHHHCCCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHCCHHHHH
KRMMLEATVFKEKNKNETTIKKSFFALNDFYLRSCTDEIAPTCSLALEIDGEAVDRYKGD
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHCCCC
GLIFSTPTGSTAYSMAAGGPIIHPSLDAIIVSAICPMSLASRPIVVPPESQLVIKPIRGM
EEEEECCCCCCEEECCCCCCEECCCHHHHHHHHHCCHHHCCCCEEECCCCCEEEECHHCC
KQKIKLWLDGSSGCLIEAEDTCLIKKSNHSTSIIILDENHSYYKTITQKLHWASSLNDPN
CEEEEEEEECCCCEEEEECCEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA