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The map label for this gene is xseA [H]

Identifier: 124024875

GI number: 124024875

Start: 156443

End: 157603

Strand: Direct

Name: xseA [H]

Synonym: NATL1_01621

Alternate gene names: 124024875

Gene position: 156443-157603 (Clockwise)

Preceding gene: 124024874

Following gene: 124024876

Centisome position: 8.39

GC content: 30.66

Gene sequence:

>1161_bases
TTGACTGATCTTAAAAACGCTAAACAATCTCTAAATACATATAGTGTTAAAGAATTAAACGAATCTATTGGCTTATTATT
ATCAAGAGGCTTTGCCCCAAAGTTTATAGTTGAAGCCACTGTTTCTAAATCGCAAATAAAAAAAGGTCATTTATGGCTAA
CTTTAACGGACGGGAAAGCAAGTGTAGATGCGGTTGCATGGTCATCAACAATAAAGTCTTTAAAATTTTTACCAAAGCAA
GATGATGGCGTTGTTATTATTGGTAAATTAAATTTCTGGGAATCTCAAGCAAGAGTATCGGTACAAGTTTTTGATATTCG
ACCAAGTATTTCTACGGTTCTTAGGAAGTTCGAAATAGTCAAATCAAAACTTTTTAAAGAAGGTTTGATTGATGATTCGT
TAAGAAAAAAATTGCCAAAATATCCTCATTCAATTGGTATCCTTACAAGTGTTCCAAGCTCTGCTTTAGCTGACATGCTT
AGAACAGCTAAGGAGAGATGGCCATTAACGAAGCTGCAAATAATTCCTATTCCAGTTCAAGGTGATAATGCAAATAAACT
AAAATCTATTTTAAGTAAATTAAAAAAAAATAAGTTAAAATTAGAGGCTTTAATTATAGCTAGAGGAGGAGGTAGCAGAG
AAGATTTAATGTTGTTTGATAGTGAAATCATAGCTAGAGAAATCGCAACTTTCCCAATACCTGTAATTACAGGGATAGGT
CACGAAGATGATCTAACAGTTGCTGATCTGGTTTCAGATCATCGATCTGCCACTCCAACTGCTGCGATTGTTGATCTATT
GCCCTCAAGAGAAATTGAAAAAAATAAGTTTTTACAAAATAAAAAATTACTTAAATATTATTTGAAATTGTTTTTTCAGA
ACGCAAAGAAATCATTAATTACAAAAAAATCTATTTTTCAATCTTATTCACCCCGACTATTAATAAAAAATAAAAGAACA
AGAATAAATTATATGTATGATATTTTGAATGCACTTTCTCCAAGAAAATTGTTAAAAAGAGGTTTTGCGCTAATTACTGA
CGAGTCAGGTAATTCGATTTATAGTGTAAAAAATATTAAGGAAAATGATAAGCTGATAGTTCAATTTTGTGATGGAAAAA
TTACAGCAGAGGTTGATAGTCTTAATTATGATAAAATATAA

Upstream 100 bases:

>100_bases
TTTAATAGGTTTAACAACAGAACTTTTAACAGGGCAAGGGATTTTAACTCAGATGGGAATCGGTTGAAAAACTAATTTTT
AGTTTTTTATTTTTAAAAGT

Downstream 100 bases:

>100_bases
ATTTATTGAATAAAAATTTGTTATTACATTCCAATTGAAAATCAAGTTATCCCAAATCATTTATCAATGTCTAACAAAGT
TACTAACAAAAAAAATATAG

Product: exonuclease VII, large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MTDLKNAKQSLNTYSVKELNESIGLLLSRGFAPKFIVEATVSKSQIKKGHLWLTLTDGKASVDAVAWSSTIKSLKFLPKQ
DDGVVIIGKLNFWESQARVSVQVFDIRPSISTVLRKFEIVKSKLFKEGLIDDSLRKKLPKYPHSIGILTSVPSSALADML
RTAKERWPLTKLQIIPIPVQGDNANKLKSILSKLKKNKLKLEALIIARGGGSREDLMLFDSEIIAREIATFPIPVITGIG
HEDDLTVADLVSDHRSATPTAAIVDLLPSREIEKNKFLQNKKLLKYYLKLFFQNAKKSLITKKSIFQSYSPRLLIKNKRT
RINYMYDILNALSPRKLLKRGFALITDESGNSIYSVKNIKENDKLIVQFCDGKITAEVDSLNYDKI

Sequences:

>Translated_386_residues
MTDLKNAKQSLNTYSVKELNESIGLLLSRGFAPKFIVEATVSKSQIKKGHLWLTLTDGKASVDAVAWSSTIKSLKFLPKQ
DDGVVIIGKLNFWESQARVSVQVFDIRPSISTVLRKFEIVKSKLFKEGLIDDSLRKKLPKYPHSIGILTSVPSSALADML
RTAKERWPLTKLQIIPIPVQGDNANKLKSILSKLKKNKLKLEALIIARGGGSREDLMLFDSEIIAREIATFPIPVITGIG
HEDDLTVADLVSDHRSATPTAAIVDLLPSREIEKNKFLQNKKLLKYYLKLFFQNAKKSLITKKSIFQSYSPRLLIKNKRT
RINYMYDILNALSPRKLLKRGFALITDESGNSIYSVKNIKENDKLIVQFCDGKITAEVDSLNYDKI
>Mature_385_residues
TDLKNAKQSLNTYSVKELNESIGLLLSRGFAPKFIVEATVSKSQIKKGHLWLTLTDGKASVDAVAWSSTIKSLKFLPKQD
DGVVIIGKLNFWESQARVSVQVFDIRPSISTVLRKFEIVKSKLFKEGLIDDSLRKKLPKYPHSIGILTSVPSSALADMLR
TAKERWPLTKLQIIPIPVQGDNANKLKSILSKLKKNKLKLEALIIARGGGSREDLMLFDSEIIAREIATFPIPVITGIGH
EDDLTVADLVSDHRSATPTAAIVDLLPSREIEKNKFLQNKKLLKYYLKLFFQNAKKSLITKKSIFQSYSPRLLIKNKRTR
INYMYDILNALSPRKLLKRGFALITDESGNSIYSVKNIKENDKLIVQFCDGKITAEVDSLNYDKI

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=314, Percent_Identity=30.5732484076433, Blast_Score=159, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 43417; Mature: 43286

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLKNAKQSLNTYSVKELNESIGLLLSRGFAPKFIVEATVSKSQIKKGHLWLTLTDGKA
CCCHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCEEEEEHHCHHHHCCCEEEEEEECCCC
SVDAVAWSSTIKSLKFLPKQDDGVVIIGKLNFWESQARVSVQVFDIRPSISTVLRKFEIV
CHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEEEEEEECCCHHHHHHHHHHH
KSKLFKEGLIDDSLRKKLPKYPHSIGILTSVPSSALADMLRTAKERWPLTKLQIIPIPVQ
HHHHHHHCCCCHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEC
GDNANKLKSILSKLKKNKLKLEALIIARGGGSREDLMLFDSEIIAREIATFPIPVITGIG
CCCHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCEEEEHHHHHHHHHHHCCCHHEECCC
HEDDLTVADLVSDHRSATPTAAIVDLLPSREIEKNKFLQNKKLLKYYLKLFFQNAKKSLI
CCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKKSIFQSYSPRLLIKNKRTRINYMYDILNALSPRKLLKRGFALITDESGNSIYSVKNIK
HHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHCCCEEEEECCCCEEEEECCCC
ENDKLIVQFCDGKITAEVDSLNYDKI
CCCEEEEEEECCEEEEEECCCCCCCC
>Mature Secondary Structure 
TDLKNAKQSLNTYSVKELNESIGLLLSRGFAPKFIVEATVSKSQIKKGHLWLTLTDGKA
CCHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCEEEEEHHCHHHHCCCEEEEEEECCCC
SVDAVAWSSTIKSLKFLPKQDDGVVIIGKLNFWESQARVSVQVFDIRPSISTVLRKFEIV
CHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEEEEEEECCCHHHHHHHHHHH
KSKLFKEGLIDDSLRKKLPKYPHSIGILTSVPSSALADMLRTAKERWPLTKLQIIPIPVQ
HHHHHHHCCCCHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEC
GDNANKLKSILSKLKKNKLKLEALIIARGGGSREDLMLFDSEIIAREIATFPIPVITGIG
CCCHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCEEEEHHHHHHHHHHHCCCHHEECCC
HEDDLTVADLVSDHRSATPTAAIVDLLPSREIEKNKFLQNKKLLKYYLKLFFQNAKKSLI
CCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKKSIFQSYSPRLLIKNKRTRINYMYDILNALSPRKLLKRGFALITDESGNSIYSVKNIK
HHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHCCCEEEEECCCCEEEEECCCC
ENDKLIVQFCDGKITAEVDSLNYDKI
CCCEEEEEEECCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA