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The map label for this gene is cynS

Identifier: 124024783

GI number: 124024783

Start: 75407

End: 75850

Strand: Reverse

Name: cynS

Synonym: NATL1_00701

Alternate gene names: 124024783

Gene position: 75850-75407 (Counterclockwise)

Preceding gene: 124024784

Following gene: 124024782

Centisome position: 4.07

GC content: 35.59

Gene sequence:

>444_bases
ATGTCATTTCCTGAATCAACTCAATTATTATTAAAAGCAAAAAAAGAAAAAGGATTAACCTTTGCAGATATTGGAATTCT
ACTAGGACTAGATGAAGTCTGGGTTGCTAGTCTTTTTTATGGACAATCAACTGCCAGTGATGAAGAGGCTGATAAATTAT
TAACTACTTTAGGACTTGGTACGGAACATAAAGAGATATTGACAACTCCACCCGTAAAAGGATCACTAGATCCAGTAATT
CCCACCGATCCATTGATATATCGTTTTTATGAAATCATGCAAGTTTATGGCATGCCAATGAAAGACGTGATTCAAGAAAA
GTTTGGTGATGGGATCATGAGTGCAATAGATTTTACAATCAATGTAGATAAAGTCGAAGATCCGAAAGGTGACAGAGTGA
AGGTTTCAATGTGTGGGAAGTTTTTACCCTACAAGAAATGGTAA

Upstream 100 bases:

>100_bases
CTAACTGAAACAATCAAGATTTAATCGTATTAGTTAATTACCTATCTAATGAATATCTCTCGTTAGATATACCTCTCTTT
ACGTTGTTAAATTTGTTTCT

Downstream 100 bases:

>100_bases
AGATTAATTCCTTTCTTTATGTTCAAGTGGTATAAAAGTGGTATATTTGAAAAAGTAATCCCTCAAATCCATTCCGGTGG
AAAAGATCTTAGGTCAAGTG

Product: cyanate hydratase

Products: NA

Alternate protein names: Cyanase; Cyanate hydrolase; Cyanate lyase

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MSFPESTQLLLKAKKEKGLTFADIGILLGLDEVWVASLFYGQSTASDEEADKLLTTLGLGTEHKEILTTPPVKGSLDPVI
PTDPLIYRFYEIMQVYGMPMKDVIQEKFGDGIMSAIDFTINVDKVEDPKGDRVKVSMCGKFLPYKKW

Sequences:

>Translated_147_residues
MSFPESTQLLLKAKKEKGLTFADIGILLGLDEVWVASLFYGQSTASDEEADKLLTTLGLGTEHKEILTTPPVKGSLDPVI
PTDPLIYRFYEIMQVYGMPMKDVIQEKFGDGIMSAIDFTINVDKVEDPKGDRVKVSMCGKFLPYKKW
>Mature_146_residues
SFPESTQLLLKAKKEKGLTFADIGILLGLDEVWVASLFYGQSTASDEEADKLLTTLGLGTEHKEILTTPPVKGSLDPVIP
TDPLIYRFYEIMQVYGMPMKDVIQEKFGDGIMSAIDFTINVDKVEDPKGDRVKVSMCGKFLPYKKW

Specific function: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide

COG id: COG1513

COG function: function code P; Cyanate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cyanase family

Homologues:

Organism=Escherichia coli, GI1786535, Length=140, Percent_Identity=43.5714285714286, Blast_Score=111, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYNS_PROM1 (A2BZH4)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001013899.1
- ProteinModelPortal:   A2BZH4
- SMR:   A2BZH4
- STRING:   A2BZH4
- GeneID:   4779099
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_00701
- eggNOG:   COG1513
- HOGENOM:   HBG317643
- OMA:   QTIPLRG
- ProtClustDB:   PRK02866
- BioCyc:   PMAR167555:NATL1_00701-MONOMER
- HAMAP:   MF_00535
- InterPro:   IPR008076
- InterPro:   IPR003712
- InterPro:   IPR010982
- Gene3D:   G3DSA:3.30.1160.10
- PIRSF:   PIRSF001263
- PRINTS:   PR01693
- TIGRFAMs:   TIGR00673

Pfam domain/function: PF02560 Cyanate_lyase; SSF55234 Cyanate_lyase_C; SSF47413 Lambda_like_DNA

EC number: =4.2.1.104

Molecular weight: Translated: 16424; Mature: 16293

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: ACT_SITE 88-88 ACT_SITE 91-91 ACT_SITE 114-114

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFPESTQLLLKAKKEKGLTFADIGILLGLDEVWVASLFYGQSTASDEEADKLLTTLGLG
CCCCHHHHHHHHHHHHCCCEEEHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
TEHKEILTTPPVKGSLDPVIPTDPLIYRFYEIMQVYGMPMKDVIQEKFGDGIMSAIDFTI
CCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHEE
NVDKVEDPKGDRVKVSMCGKFLPYKKW
ECCCCCCCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure 
SFPESTQLLLKAKKEKGLTFADIGILLGLDEVWVASLFYGQSTASDEEADKLLTTLGLG
CCCHHHHHHHHHHHHCCCEEEHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
TEHKEILTTPPVKGSLDPVIPTDPLIYRFYEIMQVYGMPMKDVIQEKFGDGIMSAIDFTI
CCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHEE
NVDKVEDPKGDRVKVSMCGKFLPYKKW
ECCCCCCCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA