Click here to switch to the map view.

The map label for this gene is argJ [H]

Identifier: 124024777

GI number: 124024777

Start: 70336

End: 71598

Strand: Direct

Name: argJ [H]

Synonym: NATL1_00641

Alternate gene names: 124024777

Gene position: 70336-71598 (Clockwise)

Preceding gene: 124024775

Following gene: 124024778

Centisome position: 3.77

GC content: 39.35

Gene sequence:

>1263_bases
GTGAAAAATGCTCTTCTGAACTTGAGTCTTTTGACATCTTCTGTATGGTCTCCAATATCTGGTGGTATTACTGCCCCTGA
TGGTTTTTTAGCAGCTGGCATTTCCGCAGGATTGAAGCCTTCTGGGAAGAAAGATCTTGCTTTGCTATATGCACCTGATG
GTGCGTGTTGCAGTGGGACATTTACTCAATCAGTGACTCGTGCTTATTGCGTGGATCTTTGTATTGATCGAATCAAGGCA
TCTGAGGGAAAAATACGTGCTGTAGTTATCAACTCTGGACATGCAAATGCTTGTACAGGCAGTCGAGGCAAAATTGATAG
TGAAATGATCACACATAAGCTTGCTCAACGCTTGAGACTATCTAGTGAAGAAGTTTTAATATGTTCTACCGGTGTAATTG
GAGAAGCAATACCTGTTGAAAAGGTTAATAGTCATTTGGATCAACTTATAAATAGTTTAGATAAAGAGGCATATCTAGAT
GCAGCAAATGCAATTTTGACAACTGATCTTCAGGTAAAGCAAATTGCATATCAAGCAGTTTTAGGAGGGAGACGAATATC
AATTGGAGGAATGGCTAAAGGTTCAGGTATGATTCATCCTTCAATGGCAACAATGTTGAGTTATCTTACCTGTGATGTAG
GCGTAGATCATGCTTTATGGTCAGATATGATTAAGCGTGTTGCAGAATCATCTTTTAATTCCATTACAGTTGATGGAGAT
ACGAGTACTAATGACACTTTTTTAGCTTTTGCTTCTGGAGCAGAATTAGATCCAAGATATTTATCAATCCTCGAAGAGGG
ACTTCATTTAACAGCTCAACACTTGGCTAAAGCTATTGCAAGGGATGGAGAAGGGGCTAATTGTTTGCTTGAGATAAAGG
TTGAAGGTGCTTCAAGTGATTTAGATGCTCGTGCAATAGCCCGTACAATTGCTTCATCCTCTCTGGTTAAAACTGCAGTC
AACGGTGCCGACCCTAATTGGGGAAGAATTATTGCTGCACTTGGTCGTGCAGGCACTTCTTTTAACTTTAATGATGTCAA
ACTATGGATTGGACCTTATGAAATCTTTTCTAATGGCACACCTCTGGACTTTGATAGACAAATAGTTAGTAACTTTATGA
AAGCAAGATTAACAGGTAAATATTTGATCGATGATCTTATCAGTATCAGATTAAGGATAGGGATAGGAATAGGCTCGGCT
ACTGCTTGGGGATGTGATTTGTCTGATCAATATGTTCGTATAAATGCCGACTATACAACGTAG

Upstream 100 bases:

>100_bases
TGGCGATACCCCCAGTGATACCTATTCTTCTCTGCTTGCCTTTCCATCTAAGACAAAGATTGTTTGTTTGTTTTTGGTCA
ATCATTAATATTGATAGTAA

Downstream 100 bases:

>100_bases
CTGAGATCTGTTGCGGCACAATAGATCTCAGCGATAGGTCTAACAAATAAAACACTAATAAAACAGTGGATTGATTATGA
CTGCGTTTTGGGCGAATTTA

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MKNALLNLSLLTSSVWSPISGGITAPDGFLAAGISAGLKPSGKKDLALLYAPDGACCSGTFTQSVTRAYCVDLCIDRIKA
SEGKIRAVVINSGHANACTGSRGKIDSEMITHKLAQRLRLSSEEVLICSTGVIGEAIPVEKVNSHLDQLINSLDKEAYLD
AANAILTTDLQVKQIAYQAVLGGRRISIGGMAKGSGMIHPSMATMLSYLTCDVGVDHALWSDMIKRVAESSFNSITVDGD
TSTNDTFLAFASGAELDPRYLSILEEGLHLTAQHLAKAIARDGEGANCLLEIKVEGASSDLDARAIARTIASSSLVKTAV
NGADPNWGRIIAALGRAGTSFNFNDVKLWIGPYEIFSNGTPLDFDRQIVSNFMKARLTGKYLIDDLISIRLRIGIGIGSA
TAWGCDLSDQYVRINADYTT

Sequences:

>Translated_420_residues
MKNALLNLSLLTSSVWSPISGGITAPDGFLAAGISAGLKPSGKKDLALLYAPDGACCSGTFTQSVTRAYCVDLCIDRIKA
SEGKIRAVVINSGHANACTGSRGKIDSEMITHKLAQRLRLSSEEVLICSTGVIGEAIPVEKVNSHLDQLINSLDKEAYLD
AANAILTTDLQVKQIAYQAVLGGRRISIGGMAKGSGMIHPSMATMLSYLTCDVGVDHALWSDMIKRVAESSFNSITVDGD
TSTNDTFLAFASGAELDPRYLSILEEGLHLTAQHLAKAIARDGEGANCLLEIKVEGASSDLDARAIARTIASSSLVKTAV
NGADPNWGRIIAALGRAGTSFNFNDVKLWIGPYEIFSNGTPLDFDRQIVSNFMKARLTGKYLIDDLISIRLRIGIGIGSA
TAWGCDLSDQYVRINADYTT
>Mature_420_residues
MKNALLNLSLLTSSVWSPISGGITAPDGFLAAGISAGLKPSGKKDLALLYAPDGACCSGTFTQSVTRAYCVDLCIDRIKA
SEGKIRAVVINSGHANACTGSRGKIDSEMITHKLAQRLRLSSEEVLICSTGVIGEAIPVEKVNSHLDQLINSLDKEAYLD
AANAILTTDLQVKQIAYQAVLGGRRISIGGMAKGSGMIHPSMATMLSYLTCDVGVDHALWSDMIKRVAESSFNSITVDGD
TSTNDTFLAFASGAELDPRYLSILEEGLHLTAQHLAKAIARDGEGANCLLEIKVEGASSDLDARAIARTIASSSLVKTAV
NGADPNWGRIIAALGRAGTSFNFNDVKLWIGPYEIFSNGTPLDFDRQIVSNFMKARLTGKYLIDDLISIRLRIGIGIGSA
TAWGCDLSDQYVRINADYTT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate [H]

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=437, Percent_Identity=32.0366132723112, Blast_Score=193, Evalue=4e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002813
- InterPro:   IPR016117 [H]

Pfam domain/function: PF01960 ArgJ [H]

EC number: =2.3.1.35; =2.3.1.1 [H]

Molecular weight: Translated: 44655; Mature: 44655

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNALLNLSLLTSSVWSPISGGITAPDGFLAAGISAGLKPSGKKDLALLYAPDGACCSGT
CCCCEEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCH
FTQSVTRAYCVDLCIDRIKASEGKIRAVVINSGHANACTGSRGKIDSEMITHKLAQRLRL
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCC
SSEEVLICSTGVIGEAIPVEKVNSHLDQLINSLDKEAYLDAANAILTTDLQVKQIAYQAV
CCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHH
LGGRRISIGGMAKGSGMIHPSMATMLSYLTCDVGVDHALWSDMIKRVAESSFNSITVDGD
HCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEECCC
TSTNDTFLAFASGAELDPRYLSILEEGLHLTAQHLAKAIARDGEGANCLLEIKVEGASSD
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCC
LDARAIARTIASSSLVKTAVNGADPNWGRIIAALGRAGTSFNFNDVKLWIGPYEIFSNGT
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCEEEEECHHHHHCCCC
PLDFDRQIVSNFMKARLTGKYLIDDLISIRLRIGIGIGSATAWGCDLSDQYVRINADYTT
CCCCCHHHHHHHHHHHHCHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MKNALLNLSLLTSSVWSPISGGITAPDGFLAAGISAGLKPSGKKDLALLYAPDGACCSGT
CCCCEEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCH
FTQSVTRAYCVDLCIDRIKASEGKIRAVVINSGHANACTGSRGKIDSEMITHKLAQRLRL
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCC
SSEEVLICSTGVIGEAIPVEKVNSHLDQLINSLDKEAYLDAANAILTTDLQVKQIAYQAV
CCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHH
LGGRRISIGGMAKGSGMIHPSMATMLSYLTCDVGVDHALWSDMIKRVAESSFNSITVDGD
HCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEECCC
TSTNDTFLAFASGAELDPRYLSILEEGLHLTAQHLAKAIARDGEGANCLLEIKVEGASSD
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCC
LDARAIARTIASSSLVKTAVNGADPNWGRIIAALGRAGTSFNFNDVKLWIGPYEIFSNGT
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCEEEEECHHHHHCCCC
PLDFDRQIVSNFMKARLTGKYLIDDLISIRLRIGIGIGSATAWGCDLSDQYVRINADYTT
CCCCCHHHHHHHHHHHHCHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA