Click here to switch to the map view.

The map label for this gene is pdxA [H]

Identifier: 124024740

GI number: 124024740

Start: 28968

End: 29993

Strand: Reverse

Name: pdxA [H]

Synonym: NATL1_00271

Alternate gene names: 124024740

Gene position: 29993-28968 (Counterclockwise)

Preceding gene: 124024741

Following gene: 124024737

Centisome position: 1.61

GC content: 33.04

Gene sequence:

>1026_bases
ATGCAAAAATCTGAAATTACAAAAGAAAATAGTACTACACTTATTATTTCATTAGGAGATCCGGCAGGAATAGGAACTGA
AATAACATTAAAAGCTCTGGGCTCTAAAAGCCTAAACAAAAATATAAAGCCTTTACTTGTAGGATGCAAAAATAATATTC
ATGAAACCTATTCAAAATTAATTAAACATGGAATAGATAATATTCCCGACCCAAACAAACTTCATATTATTGATATCCCT
TTAGAAAATAAAGTTACTCCAGGAATAATTGACAAGTATACTGGGTCTGCAAGCTTTAAATGGCTTTTGAATGCAACTAA
TATACTGTTAGAAGGAAAAGCTAATGCTCTAGTAACAGCACCTATTTCTAAAATTGCTTGGCATAAAGCTGGGCATAAAT
TTGCAGGACAAACTGAATTATTAGGTAAATTAACTAACAAAAAAACATCTATGCTTTTTACAGCAATTTCACCAAATAAT
GGATGGAGATTTAATACTTTATTAGCTACAACACATATACCACTTAATAAAATAAATGATACTTTAACCAAAGAATTGAT
TAAACATAAATTAGATACCTTATTGAATTTCTGTCGTAAGTTTAAAGAGAAGCCATCAATACAAATAGCCGGCTTAAATC
CACATGCTGGGGAAGAAGGAAAAATTGGTATGGAAGAACAAAACTTAATTATTCCTATTTTAAATGAATGGAAATTAGAT
AATCCAGACATCAAAATTATTGGGCCCATCCCTCCAGATACCTGTTGGATTACATCAGTAAATGCATGGAATGGAGCCTC
AATTAAAAACAATGCACCTGATGGAATACTCGCTTTGTATCACGATCAAGGTCTGATCCCTGTCAAGCTAATTGCTTTTG
ATGAAGCCGTTAACACAACTCTTGGGTTGCCTTTTGTAAGAACATCACCTGATCATGGGACAGCTCTTGATATTGCAGGA
ATGTTCAAGGCAAGAGAAAAAAGTATGGTTGCAGCAATGAATAACGCTTGGCTTCTGTCTCAATAA

Upstream 100 bases:

>100_bases
AAGTAAATCCAAGATTATAAAAACTTATTCCAATCTATTCCAAGCCAACTATTACAAATAACTTGGCTAAAAAATCAAAA
CCCCAAGAAAACATCAAAAC

Downstream 100 bases:

>100_bases
GTAAAAACTTTTACACAGGTTTTAATCTCATTAAAACTTGACCAAACTCGACTGGTGTTCCGTTCTCTACAAGAATTTCA
ATTACTTCACCACTTACCTC

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MQKSEITKENSTTLIISLGDPAGIGTEITLKALGSKSLNKNIKPLLVGCKNNIHETYSKLIKHGIDNIPDPNKLHIIDIP
LENKVTPGIIDKYTGSASFKWLLNATNILLEGKANALVTAPISKIAWHKAGHKFAGQTELLGKLTNKKTSMLFTAISPNN
GWRFNTLLATTHIPLNKINDTLTKELIKHKLDTLLNFCRKFKEKPSIQIAGLNPHAGEEGKIGMEEQNLIIPILNEWKLD
NPDIKIIGPIPPDTCWITSVNAWNGASIKNNAPDGILALYHDQGLIPVKLIAFDEAVNTTLGLPFVRTSPDHGTALDIAG
MFKAREKSMVAAMNNAWLLSQ

Sequences:

>Translated_341_residues
MQKSEITKENSTTLIISLGDPAGIGTEITLKALGSKSLNKNIKPLLVGCKNNIHETYSKLIKHGIDNIPDPNKLHIIDIP
LENKVTPGIIDKYTGSASFKWLLNATNILLEGKANALVTAPISKIAWHKAGHKFAGQTELLGKLTNKKTSMLFTAISPNN
GWRFNTLLATTHIPLNKINDTLTKELIKHKLDTLLNFCRKFKEKPSIQIAGLNPHAGEEGKIGMEEQNLIIPILNEWKLD
NPDIKIIGPIPPDTCWITSVNAWNGASIKNNAPDGILALYHDQGLIPVKLIAFDEAVNTTLGLPFVRTSPDHGTALDIAG
MFKAREKSMVAAMNNAWLLSQ
>Mature_341_residues
MQKSEITKENSTTLIISLGDPAGIGTEITLKALGSKSLNKNIKPLLVGCKNNIHETYSKLIKHGIDNIPDPNKLHIIDIP
LENKVTPGIIDKYTGSASFKWLLNATNILLEGKANALVTAPISKIAWHKAGHKFAGQTELLGKLTNKKTSMLFTAISPNN
GWRFNTLLATTHIPLNKINDTLTKELIKHKLDTLLNFCRKFKEKPSIQIAGLNPHAGEEGKIGMEEQNLIIPILNEWKLD
NPDIKIIGPIPPDTCWITSVNAWNGASIKNNAPDGILALYHDQGLIPVKLIAFDEAVNTTLGLPFVRTSPDHGTALDIAG
MFKAREKSMVAAMNNAWLLSQ

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=337, Percent_Identity=34.7181008902077, Blast_Score=156, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 37345; Mature: 37345

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKSEITKENSTTLIISLGDPAGIGTEITLKALGSKSLNKNIKPLLVGCKNNIHETYSKL
CCCCCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHH
IKHGIDNIPDPNKLHIIDIPLENKVTPGIIDKYTGSASFKWLLNATNILLEGKANALVTA
HHHCCCCCCCCCEEEEEEECCCCCCCCCHHHCCCCCCEEEEEEEEEEEEEECCCCEEEEC
PISKIAWHKAGHKFAGQTELLGKLTNKKTSMLFTAISPNNGWRFNTLLATTHIPLNKIND
CHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCEEEEEEEEEECCCHHHHHH
TLTKELIKHKLDTLLNFCRKFKEKPSIQIAGLNPHAGEEGKIGMEEQNLIIPILNEWKLD
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCC
NPDIKIIGPIPPDTCWITSVNAWNGASIKNNAPDGILALYHDQGLIPVKLIAFDEAVNTT
CCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECHHHHHH
LGLPFVRTSPDHGTALDIAGMFKAREKSMVAAMNNAWLLSQ
CCCCEEEECCCCCCEEEHHHHHHHHHHHHEEEECCEEEECC
>Mature Secondary Structure
MQKSEITKENSTTLIISLGDPAGIGTEITLKALGSKSLNKNIKPLLVGCKNNIHETYSKL
CCCCCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHH
IKHGIDNIPDPNKLHIIDIPLENKVTPGIIDKYTGSASFKWLLNATNILLEGKANALVTA
HHHCCCCCCCCCEEEEEEECCCCCCCCCHHHCCCCCCEEEEEEEEEEEEEECCCCEEEEC
PISKIAWHKAGHKFAGQTELLGKLTNKKTSMLFTAISPNNGWRFNTLLATTHIPLNKIND
CHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCEEEEEEEEEECCCHHHHHH
TLTKELIKHKLDTLLNFCRKFKEKPSIQIAGLNPHAGEEGKIGMEEQNLIIPILNEWKLD
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCC
NPDIKIIGPIPPDTCWITSVNAWNGASIKNNAPDGILALYHDQGLIPVKLIAFDEAVNTT
CCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECHHHHHH
LGLPFVRTSPDHGTALDIAGMFKAREKSMVAAMNNAWLLSQ
CCCCEEEECCCCCCEEEHHHHHHHHHHHHEEEECCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA