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The map label for this gene is msrB [H]

Identifier: 124024727

GI number: 124024727

Start: 18170

End: 18637

Strand: Direct

Name: msrB [H]

Synonym: NATL1_00141

Alternate gene names: 124024727

Gene position: 18170-18637 (Clockwise)

Preceding gene: 124024725

Following gene: 124024728

Centisome position: 0.97

GC content: 38.25

Gene sequence:

>468_bases
ATGTTTGGACTCTTGAATACTCTTTTTGGTTTTACTATCGAACCAAAAAGCGCTTTTGCCTCCTCTAAACCTATGGAAAA
CTATAAAACTCTAACTGATGCAGACTGGGAAAATCGTTTACCCAAAGACGCTTTTTACGTCTTACGAAAGGAAGGAACAG
AGAGACCGTTTTCAAGTTCATTAAATGATGAAAAAAGGAAAGGAGTTTTTCGTTGTGCAGGATGCGGTCTTGCTTTATTT
TCTTCAACAACAAAGTTTGACAGTGGAACAGGCTGGCCAAGTTTTTTTGATCATTTACCGGATGCAATAGAGACAAAAAC
AGACTTCAAATTAATTGTCCCTAGAACTGAATATCATTGCCGAAGATGTGGTGGGCATCAAGGACATGTTTTTAATGATG
GTCCAAGACCCACTGGTAAACGATATTGTAATAATGGTGTCGCTCTTGCTTTCGAAGTTGATTCGTAA

Upstream 100 bases:

>100_bases
TTGGAAATCATTTTTTATGAATTAATTTTTTCAACTTTTAGGGAGGAAATTTTATTAAGATTCACTGAATTGAGAAATTT
CTTTGAAACGTAGATTTTTT

Downstream 100 bases:

>100_bases
ATGATTATCTTTTCTATTCAAATAGGTGTGGGCTTCCGTAGCTTGTACAAAAAACCCTTTGCAATCAACATGGTCTAAAA
GCTGATTGAATTATATGAAT

Product: hypothetical protein

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MFGLLNTLFGFTIEPKSAFASSKPMENYKTLTDADWENRLPKDAFYVLRKEGTERPFSSSLNDEKRKGVFRCAGCGLALF
SSTTKFDSGTGWPSFFDHLPDAIETKTDFKLIVPRTEYHCRRCGGHQGHVFNDGPRPTGKRYCNNGVALAFEVDS

Sequences:

>Translated_155_residues
MFGLLNTLFGFTIEPKSAFASSKPMENYKTLTDADWENRLPKDAFYVLRKEGTERPFSSSLNDEKRKGVFRCAGCGLALF
SSTTKFDSGTGWPSFFDHLPDAIETKTDFKLIVPRTEYHCRRCGGHQGHVFNDGPRPTGKRYCNNGVALAFEVDS
>Mature_155_residues
MFGLLNTLFGFTIEPKSAFASSKPMENYKTLTDADWENRLPKDAFYVLRKEGTERPFSSSLNDEKRKGVFRCAGCGLALF
SSTTKFDSGTGWPSFFDHLPDAIETKTDFKLIVPRTEYHCRRCGGHQGHVFNDGPRPTGKRYCNNGVALAFEVDS

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=133, Percent_Identity=43.609022556391, Blast_Score=117, Evalue=5e-27,
Organism=Homo sapiens, GI301336162, Length=133, Percent_Identity=43.609022556391, Blast_Score=117, Evalue=5e-27,
Organism=Homo sapiens, GI73089054, Length=133, Percent_Identity=43.609022556391, Blast_Score=117, Evalue=5e-27,
Organism=Homo sapiens, GI37620216, Length=123, Percent_Identity=44.7154471544715, Blast_Score=116, Evalue=8e-27,
Organism=Homo sapiens, GI117606353, Length=130, Percent_Identity=43.0769230769231, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI1788077, Length=118, Percent_Identity=44.0677966101695, Blast_Score=105, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17553450, Length=133, Percent_Identity=42.8571428571429, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI115532676, Length=133, Percent_Identity=42.8571428571429, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319816, Length=129, Percent_Identity=37.984496124031, Blast_Score=90, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45553335, Length=125, Percent_Identity=44, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21356369, Length=125, Percent_Identity=44, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24645799, Length=125, Percent_Identity=44, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24645804, Length=135, Percent_Identity=41.4814814814815, Blast_Score=106, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24645801, Length=135, Percent_Identity=41.4814814814815, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI221378662, Length=131, Percent_Identity=39.6946564885496, Blast_Score=102, Evalue=7e-23,
Organism=Drosophila melanogaster, GI221378664, Length=125, Percent_Identity=41.6, Blast_Score=102, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 17418; Mature: 17418

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGLLNTLFGFTIEPKSAFASSKPMENYKTLTDADWENRLPKDAFYVLRKEGTERPFSSS
CCCHHHHHHCCEECCHHHHCCCCCCHHHCCCCCCCHHHCCCHHHHHHHHCCCCCCCCCCC
LNDEKRKGVFRCAGCGLALFSSTTKFDSGTGWPSFFDHLPDAIETKTDFKLIVPRTEYHC
CCCHHHCCEEEECCCCHHHHCCCCCCCCCCCCHHHHHHCCHHHCCCCCCEEEECCCHHHH
RRCGGHQGHVFNDGPRPTGKRYCNNGVALAFEVDS
HHCCCCCCCCCCCCCCCCCHHHCCCCEEEEEEECC
>Mature Secondary Structure
MFGLLNTLFGFTIEPKSAFASSKPMENYKTLTDADWENRLPKDAFYVLRKEGTERPFSSS
CCCHHHHHHCCEECCHHHHCCCCCCHHHCCCCCCCHHHCCCHHHHHHHHCCCCCCCCCCC
LNDEKRKGVFRCAGCGLALFSSTTKFDSGTGWPSFFDHLPDAIETKTDFKLIVPRTEYHC
CCCHHHCCEEEECCCCHHHHCCCCCCCCCCCCHHHHHHCCHHHCCCCCCEEEECCCHHHH
RRCGGHQGHVFNDGPRPTGKRYCNNGVALAFEVDS
HHCCCCCCCCCCCCCCCCCHHHCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA