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The map label for this gene is grxC [C]

Identifier: 124024425

GI number: 124024425

Start: 2411742

End: 2412005

Strand: Reverse

Name: grxC [C]

Synonym: P9303_27371

Alternate gene names: 124024425

Gene position: 2412005-2411742 (Counterclockwise)

Preceding gene: 124024431

Following gene: 124024424

Centisome position: 89.91

GC content: 57.58

Gene sequence:

>264_bases
ATGGCCAAGGTTGAGATCTATACCTGGCAGTCATGCCCTTTCTGCCTGCGTGCCAAGGCTCTCTTGGATCGCAAAGGGGT
GAGTTACCAGGAGCACGCCATCGATGGCGACCAGGATGCCCGCGCAGCGATGGCGAACCGGGCTGGGGGGAGTAACACGT
TGCCCCAGATCTTTATCGATGATCTGAGCATCGGTGGCTGCGATGAGTTGCATGCCCTTGAGGGGGCTCAAAAACTTGAT
GGTTTGCTCCAAGGCAAGGGCTGA

Upstream 100 bases:

>100_bases
AAGTCGGTGAGGTCCAGCAACGTTGGTGCTTGAGTCCAGAGATCTGACGCTATCAGCGTGGCCAGCCTGCATAGGATCTC
AGTGACGTCATCACAGTGCC

Downstream 100 bases:

>100_bases
CGCCATGCGACAGCTGTTCGTCTTGGACCCCCTGCAGTGCATTCAACCTGCCAAGGATTCCTCAGCTGCGTTGATGCAGG
CGGCCCAACGGGCATCGATT

Product: glutaredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 87; Mature: 86

Protein sequence:

>87_residues
MAKVEIYTWQSCPFCLRAKALLDRKGVSYQEHAIDGDQDARAAMANRAGGSNTLPQIFIDDLSIGGCDELHALEGAQKLD
GLLQGKG

Sequences:

>Translated_87_residues
MAKVEIYTWQSCPFCLRAKALLDRKGVSYQEHAIDGDQDARAAMANRAGGSNTLPQIFIDDLSIGGCDELHALEGAQKLD
GLLQGKG
>Mature_86_residues
AKVEIYTWQSCPFCLRAKALLDRKGVSYQEHAIDGDQDARAAMANRAGGSNTLPQIFIDDLSIGGCDELHALEGAQKLDG
LLQGKG

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaredoxin family [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=84, Percent_Identity=57.1428571428571, Blast_Score=95, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9364; Mature: 9232

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVEIYTWQSCPFCLRAKALLDRKGVSYQEHAIDGDQDARAAMANRAGGSNTLPQIFID
CCEEEEEEECCCCHHHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHHCCCCCCCCCEEEEC
DLSIGGCDELHALEGAQKLDGLLQGKG
CCCCCCCCHHHHHCCHHHHHHHHCCCC
>Mature Secondary Structure 
AKVEIYTWQSCPFCLRAKALLDRKGVSYQEHAIDGDQDARAAMANRAGGSNTLPQIFID
CEEEEEEECCCCHHHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHHCCCCCCCCCEEEEC
DLSIGGCDELHALEGAQKLDGLLQGKG
CCCCCCCCHHHHHCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]