Click here to switch to the map view.

The map label for this gene is kdsB [H]

Identifier: 124024242

GI number: 124024242

Start: 2246657

End: 2247472

Strand: Reverse

Name: kdsB [H]

Synonym: P9303_25531

Alternate gene names: 124024242

Gene position: 2247472-2246657 (Counterclockwise)

Preceding gene: 124024243

Following gene: 124024238

Centisome position: 83.78

GC content: 53.06

Gene sequence:

>816_bases
ATGGGAGTTCAACGCTGTGTCGTGGCCGTGCCTGCAAGGCTTGAATCATCGCGATTACCCAATAAGGTTCTGGCAGATAT
CGGCGGGATGCCAATGCTGCAGCGTGTTCTTGAGCGCTGCAGTCAGGCTCATGGGCCAACGGCGGTTGTCCTTTGCACGG
ATAGTGATCGATTGAAAGAGATGGCGGAAGACTGGGGTTTCCCGGTGTTGATGACTTCGGCTTCGTGCAGTTCAGGTAGC
GAAAGAATTGCTTCGGTTGCCGATCATTTGGTTGCCATGGCCTGGGATGAGCAAGCTGATGGTTGGGATCAGCAGCAGCA
GCAACAGCGGTTGGCTATGACTGCAGTGATCAATGTGCAAGGGGATCAGCCGTTCTTGGACCCTGCGGTGGTGACGACAA
TGGCGATGGAGTTTGAGCAGAGAGAGATTGTTCCAGCTGTGATAACTCCGGTTTACCGACTCAAGCCCGAGACCATCCAT
AACCCCAATGTGGTTAAGACCTTATTGGCTATTGACGGCCGAGCGCTTTATTTTTCTCGCTCGGCGATTCCGCATGTGCG
CGATGTGGACCCTTTGGATTGGCATCGCCATGCCACCTACTGGGGGCATGTGGGGATGTATGGCTTTCGAGGAGATGTGT
TGGCTTGCTGGTCAGGTATGCCGCCTTCGCCTTTGGAAGCTCTTGAACGTCTAGAGCAATTGCGATTGATTGAAGCTGGT
CATACGATTTCCACTTTTGCAGTTGAGGGGACATCCCTTTCGGTGGATACGGTTGAGCAGTTGGAAGAAGCTAGGGAATG
TGCCTTGAAATCTTGA

Upstream 100 bases:

>100_bases
GTGGACCATGGTTCCGCGAACAGCGCACGATGGGTGGTGCCTTAGCGGCTGAATGGTTTAGTGCTCGTGATGATGCGATG
AAGCTTTGGGATTGATGCCG

Downstream 100 bases:

>100_bases
TCGTGAAGCCAAGCTGAATGGCATTTATTGGTCTCTGCACCAAGTTGCAGATGTTGACCATATTGAGTCAATATTGACAT
GCGGTAATTGATTTTTGACT

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MGVQRCVVAVPARLESSRLPNKVLADIGGMPMLQRVLERCSQAHGPTAVVLCTDSDRLKEMAEDWGFPVLMTSASCSSGS
ERIASVADHLVAMAWDEQADGWDQQQQQQRLAMTAVINVQGDQPFLDPAVVTTMAMEFEQREIVPAVITPVYRLKPETIH
NPNVVKTLLAIDGRALYFSRSAIPHVRDVDPLDWHRHATYWGHVGMYGFRGDVLACWSGMPPSPLEALERLEQLRLIEAG
HTISTFAVEGTSLSVDTVEQLEEARECALKS

Sequences:

>Translated_271_residues
MGVQRCVVAVPARLESSRLPNKVLADIGGMPMLQRVLERCSQAHGPTAVVLCTDSDRLKEMAEDWGFPVLMTSASCSSGS
ERIASVADHLVAMAWDEQADGWDQQQQQQRLAMTAVINVQGDQPFLDPAVVTTMAMEFEQREIVPAVITPVYRLKPETIH
NPNVVKTLLAIDGRALYFSRSAIPHVRDVDPLDWHRHATYWGHVGMYGFRGDVLACWSGMPPSPLEALERLEQLRLIEAG
HTISTFAVEGTSLSVDTVEQLEEARECALKS
>Mature_270_residues
GVQRCVVAVPARLESSRLPNKVLADIGGMPMLQRVLERCSQAHGPTAVVLCTDSDRLKEMAEDWGFPVLMTSASCSSGSE
RIASVADHLVAMAWDEQADGWDQQQQQQRLAMTAVINVQGDQPFLDPAVVTTMAMEFEQREIVPAVITPVYRLKPETIHN
PNVVKTLLAIDGRALYFSRSAIPHVRDVDPLDWHRHATYWGHVGMYGFRGDVLACWSGMPPSPLEALERLEQLRLIEAGH
TISTFAVEGTSLSVDTVEQLEEARECALKS

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=269, Percent_Identity=35.6877323420074, Blast_Score=135, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 29962; Mature: 29830

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVQRCVVAVPARLESSRLPNKVLADIGGMPMLQRVLERCSQAHGPTAVVLCTDSDRLKE
CCHHHHHHHHCHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHH
MAEDWGFPVLMTSASCSSGSERIASVADHLVAMAWDEQADGWDQQQQQQRLAMTAVINVQ
HHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEEEEC
GDQPFLDPAVVTTMAMEFEQREIVPAVITPVYRLKPETIHNPNVVKTLLAIDGRALYFSR
CCCCCCCHHHHHHHHHHHHHHHCCHHHHCHHHHCCCCCCCCCHHHHHHHHHCCCEEEEEC
SAIPHVRDVDPLDWHRHATYWGHVGMYGFRGDVLACWSGMPPSPLEALERLEQLRLIEAG
CCCCCCCCCCCCCHHHCCCEECCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHCC
HTISTFAVEGTSLSVDTVEQLEEARECALKS
CCEEEEEECCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GVQRCVVAVPARLESSRLPNKVLADIGGMPMLQRVLERCSQAHGPTAVVLCTDSDRLKE
CHHHHHHHHCHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHH
MAEDWGFPVLMTSASCSSGSERIASVADHLVAMAWDEQADGWDQQQQQQRLAMTAVINVQ
HHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEEEEC
GDQPFLDPAVVTTMAMEFEQREIVPAVITPVYRLKPETIHNPNVVKTLLAIDGRALYFSR
CCCCCCCHHHHHHHHHHHHHHHCCHHHHCHHHHCCCCCCCCCHHHHHHHHHCCCEEEEEC
SAIPHVRDVDPLDWHRHATYWGHVGMYGFRGDVLACWSGMPPSPLEALERLEQLRLIEAG
CCCCCCCCCCCCCHHHCCCEECCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHCC
HTISTFAVEGTSLSVDTVEQLEEARECALKS
CCEEEEEECCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA