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The map label for this gene is 124024085

Identifier: 124024085

GI number: 124024085

Start: 2109259

End: 2109927

Strand: Reverse

Name: 124024085

Synonym: P9303_23941

Alternate gene names: NA

Gene position: 2109927-2109259 (Counterclockwise)

Preceding gene: 124024087

Following gene: 124024084

Centisome position: 78.65

GC content: 56.2

Gene sequence:

>669_bases
GTGAAGAAGGTTGTTGCTCCAGCCACGCCCATAGCCACTACTTCCATCGCCAAGGATTTCCCGCCCTTACCCAAATCCTT
CTTCTGCCGCCCTGCAGAAGTTGTTGGTCCTGAGTTGGTGGGCTGCAGGTTGGTGAAACGCCAAGCGGATGGCAGTTTGC
TTTGGGGCGTGATTGTGGAAACAGAGGCGTATTCACAGGATGAGCCTGCCTGCCATGGCTACCGCCGCCGTTCACCGCAG
AACGAAACGCTGTTTGGTGAGCCAGGGCGTTTCTATGTGTATGTGAGCTATGGCATCCACCACTGCGTGAATGTGGTGAC
GGATCGAGCCGAATGGGCCAATGGTGTTTTGTTGAGGGCGATTGCACTGCCGGACGAACCGGAACGCGTCGCGGCGGGGC
CAGCTTTATTGGCGCGTCGTTTTGGTTTGGATCGCTCCCATGACAGAGCAGCCGTCACAGGAGAGAATGATGTGTGGCTG
GCACCTAGGCCAGCTGCTTTCGGTACGCCAACGATTGTGAGCACAACCAGGATCGGTATCTCTCAAGGACAAGACATTCC
TTGGCGTTGGTATCTCAAGAACTGTCGCAGTATTAGTCGCCGTGCCAAGGGAGATCGCACGCCGCTTTTGCAGCAAGCCT
GGGCTCCTGTTGCTAGTGATGGTCAATGA

Upstream 100 bases:

>100_bases
AACCTTCTCTAGGAATGCTTTGAGTTGCTCTTCTGACATCTGAGAGAAAGGGCTTTGTTCATTTCATTATCTCTTCTTCA
AGCAGCGTTGTCAGACTTGG

Downstream 100 bases:

>100_bases
GCGGTTGGTCCCATCGGCATATCCTTGATCTGGCCAGCTTCTCCCTTGAGGATTACAGCTCTGTTCTGGAGCTAGCGCAT
CGTTTCCGCTCGATGCCTGT

Product: methylpurine-DNA glycosylase (MPG)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MKKVVAPATPIATTSIAKDFPPLPKSFFCRPAEVVGPELVGCRLVKRQADGSLLWGVIVETEAYSQDEPACHGYRRRSPQ
NETLFGEPGRFYVYVSYGIHHCVNVVTDRAEWANGVLLRAIALPDEPERVAAGPALLARRFGLDRSHDRAAVTGENDVWL
APRPAAFGTPTIVSTTRIGISQGQDIPWRWYLKNCRSISRRAKGDRTPLLQQAWAPVASDGQ

Sequences:

>Translated_222_residues
MKKVVAPATPIATTSIAKDFPPLPKSFFCRPAEVVGPELVGCRLVKRQADGSLLWGVIVETEAYSQDEPACHGYRRRSPQ
NETLFGEPGRFYVYVSYGIHHCVNVVTDRAEWANGVLLRAIALPDEPERVAAGPALLARRFGLDRSHDRAAVTGENDVWL
APRPAAFGTPTIVSTTRIGISQGQDIPWRWYLKNCRSISRRAKGDRTPLLQQAWAPVASDGQ
>Mature_222_residues
MKKVVAPATPIATTSIAKDFPPLPKSFFCRPAEVVGPELVGCRLVKRQADGSLLWGVIVETEAYSQDEPACHGYRRRSPQ
NETLFGEPGRFYVYVSYGIHHCVNVVTDRAEWANGVLLRAIALPDEPERVAAGPALLARRFGLDRSHDRAAVTGENDVWL
APRPAAFGTPTIVSTTRIGISQGQDIPWRWYLKNCRSISRRAKGDRTPLLQQAWAPVASDGQ

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family [H]

Homologues:

Organism=Homo sapiens, GI62632769, Length=159, Percent_Identity=30.8176100628931, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI62632771, Length=159, Percent_Identity=30.8176100628931, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI62632765, Length=159, Percent_Identity=30.8176100628931, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011034
- InterPro:   IPR003180 [H]

Pfam domain/function: PF02245 Pur_DNA_glyco [H]

EC number: 3.2.2.-

Molecular weight: Translated: 24475; Mature: 24475

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVVAPATPIATTSIAKDFPPLPKSFFCRPAEVVGPELVGCRLVKRQADGSLLWGVIVE
CCCCCCCCCCCHHHHHHHCCCCCCHHHCCCCHHHCCCHHHHHHHHHHCCCCCEEEEEEEE
TEAYSQDEPACHGYRRRSPQNETLFGEPGRFYVYVSYGIHHCVNVVTDRAEWANGVLLRA
CCCCCCCCCCHHHHHHCCCCCCCEECCCCCEEEEEEHHHHHHHHHHHHHHHHHCCEEEEE
IALPDEPERVAAGPALLARRFGLDRSHDRAAVTGENDVWLAPRPAAFGTPTIVSTTRIGI
EECCCCCHHHHCCHHHHHHHHCCCCCCCCEEEECCCCEEECCCCCCCCCCCEEEEEEECC
SQGQDIPWRWYLKNCRSISRRAKGDRTPLLQQAWAPVASDGQ
CCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKKVVAPATPIATTSIAKDFPPLPKSFFCRPAEVVGPELVGCRLVKRQADGSLLWGVIVE
CCCCCCCCCCCHHHHHHHCCCCCCHHHCCCCHHHCCCHHHHHHHHHHCCCCCEEEEEEEE
TEAYSQDEPACHGYRRRSPQNETLFGEPGRFYVYVSYGIHHCVNVVTDRAEWANGVLLRA
CCCCCCCCCCHHHHHHCCCCCCCEECCCCCEEEEEEHHHHHHHHHHHHHHHHHCCEEEEE
IALPDEPERVAAGPALLARRFGLDRSHDRAAVTGENDVWLAPRPAAFGTPTIVSTTRIGI
EECCCCCHHHHCCHHHHHHHHCCCCCCCCEEEECCCCEEECCCCCCCCCCCEEEEEEECC
SQGQDIPWRWYLKNCRSISRRAKGDRTPLLQQAWAPVASDGQ
CCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA