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The map label for this gene is pheA [H]

Identifier: 124024060

GI number: 124024060

Start: 2087116

End: 2088030

Strand: Reverse

Name: pheA [H]

Synonym: P9303_23691

Alternate gene names: 124024060

Gene position: 2088030-2087116 (Counterclockwise)

Preceding gene: 124024062

Following gene: 124024051

Centisome position: 77.83

GC content: 55.08

Gene sequence:

>915_bases
TTGGAAAGCCAGAGGCATGGCTTGCGGTTGACGCGTCATGATCCTATCGACCTCACTTGCGATGCGCTTCTGATGCCAAT
ACGCGTGGCCTTCCTCGGACCGGAGGGAACCTATGGTCAGCAAGCGGCCCAAGCTCTGGCGGAGCTTGAGGGATTAGCAA
ATTTTGAGCTGGTGCCATGTATAGGTCTGCGTTCTGTCGTTGAGCATGTGGCCACTAAACGCTCTGAAATGGCGGTGGTT
CCGGTTGAGAATTCCGTGGAGGGTGGTGTAACTGCCAGCTTGGATGCGCTTTGGTCTCATCCGCAGTTATGCATCCTTAG
GGCAGTGGTTTTGCCGATTCGTCATGCTCTACTGAGCAGTGGCGGACTCAAAGACATCTCTGAAGTCCTGTCTCACCCCC
AAGCTCTGGCTCAGTGCAGTGGCTGGTTGGCTGATCATCTTCCTGATGCGCTGCAGTTGCCTACAAGTTCTACGGCCGAG
GCGGCCAGAATGGTTATAGATAGTCGATTTCGGGCAGCGATCGCTTCTCGGCCTACGGGCCAGGGAAGAGGCCTTAAAGA
ACTGGCTTTCCCTATCAACGATGTCGCGGGCAATCGCACCAGATTCCTGTTGTTACGGCAGGGAACACCGCTGCAACGTG
GTGATGTGGCCAGCTTCGCATTCTCTCTGCATGCCAACGCCCCGGGCAGCCTGCTCGAAGCACTCACTTGTGTGGCTCGA
CTGGGGTTCAATATGAGTCGGATTGAGTCGCGTCCCTCGAAGCGAGAACTAGGTGAATACGTGTTCTTTGTGGATGTGGA
ATTGAGGGATGGGGGTGTTGGTGCATCTGAGCAGCTCATCGAGGCCTTGCAGCCTTTCTGTGAACATCTTGTGCATTTCG
GCTCTTATCTCAGCAGCGACTTGGAGCTCGATTGA

Upstream 100 bases:

>100_bases
CCCATTCCAGTAGAGCAGCCAGAACCCTATCCTGCTCGAGCAGGTAAGCAGGCAGTCGCTCAGCGTTTTGCCTTACCGGC
AAATTGAGGTTCTGGCTGGC

Downstream 100 bases:

>100_bases
GATCAGTCGCGGCTGCGGAAGACACCGAATTGCATCAGACCATGGGCAAAAGCCCAGCGCATCAACAAAATCGTTGGTAT
TTCTCTGAATCCCTTGACCA

Product: chorismate mutase-prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MESQRHGLRLTRHDPIDLTCDALLMPIRVAFLGPEGTYGQQAAQALAELEGLANFELVPCIGLRSVVEHVATKRSEMAVV
PVENSVEGGVTASLDALWSHPQLCILRAVVLPIRHALLSSGGLKDISEVLSHPQALAQCSGWLADHLPDALQLPTSSTAE
AARMVIDSRFRAAIASRPTGQGRGLKELAFPINDVAGNRTRFLLLRQGTPLQRGDVASFAFSLHANAPGSLLEALTCVAR
LGFNMSRIESRPSKRELGEYVFFVDVELRDGGVGASEQLIEALQPFCEHLVHFGSYLSSDLELD

Sequences:

>Translated_304_residues
MESQRHGLRLTRHDPIDLTCDALLMPIRVAFLGPEGTYGQQAAQALAELEGLANFELVPCIGLRSVVEHVATKRSEMAVV
PVENSVEGGVTASLDALWSHPQLCILRAVVLPIRHALLSSGGLKDISEVLSHPQALAQCSGWLADHLPDALQLPTSSTAE
AARMVIDSRFRAAIASRPTGQGRGLKELAFPINDVAGNRTRFLLLRQGTPLQRGDVASFAFSLHANAPGSLLEALTCVAR
LGFNMSRIESRPSKRELGEYVFFVDVELRDGGVGASEQLIEALQPFCEHLVHFGSYLSSDLELD
>Mature_304_residues
MESQRHGLRLTRHDPIDLTCDALLMPIRVAFLGPEGTYGQQAAQALAELEGLANFELVPCIGLRSVVEHVATKRSEMAVV
PVENSVEGGVTASLDALWSHPQLCILRAVVLPIRHALLSSGGLKDISEVLSHPQALAQCSGWLADHLPDALQLPTSSTAE
AARMVIDSRFRAAIASRPTGQGRGLKELAFPINDVAGNRTRFLLLRQGTPLQRGDVASFAFSLHANAPGSLLEALTCVAR
LGFNMSRIESRPSKRELGEYVFFVDVELRDGGVGASEQLIEALQPFCEHLVHFGSYLSSDLELD

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=246, Percent_Identity=32.520325203252, Blast_Score=97, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324013, Length=322, Percent_Identity=26.3975155279503, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 32877; Mature: 32877

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESQRHGLRLTRHDPIDLTCDALLMPIRVAFLGPEGTYGQQAAQALAELEGLANFELVPC
CCCCCCCCEEECCCCCCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCCCCEECH
IGLRSVVEHVATKRSEMAVVPVENSVEGGVTASLDALWSHPQLCILRAVVLPIRHALLSS
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
GGLKDISEVLSHPQALAQCSGWLADHLPDALQLPTSSTAEAARMVIDSRFRAAIASRPTG
CCHHHHHHHHHCHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
QGRGLKELAFPINDVAGNRTRFLLLRQGTPLQRGDVASFAFSLHANAPGSLLEALTCVAR
CCCCHHHHHCCHHHCCCCCEEEEEEECCCCCCCCCHHHHEEEECCCCCHHHHHHHHHHHH
LGFNMSRIESRPSKRELGEYVFFVDVELRDGGVGASEQLIEALQPFCEHLVHFGSYLSSD
HCCCHHHHHCCCCHHHHCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
LELD
CCCC
>Mature Secondary Structure
MESQRHGLRLTRHDPIDLTCDALLMPIRVAFLGPEGTYGQQAAQALAELEGLANFELVPC
CCCCCCCCEEECCCCCCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCCCCEECH
IGLRSVVEHVATKRSEMAVVPVENSVEGGVTASLDALWSHPQLCILRAVVLPIRHALLSS
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
GGLKDISEVLSHPQALAQCSGWLADHLPDALQLPTSSTAEAARMVIDSRFRAAIASRPTG
CCHHHHHHHHHCHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
QGRGLKELAFPINDVAGNRTRFLLLRQGTPLQRGDVASFAFSLHANAPGSLLEALTCVAR
CCCCHHHHHCCHHHCCCCCEEEEEEECCCCCCCCCHHHHEEEECCCCCHHHHHHHHHHHH
LGFNMSRIESRPSKRELGEYVFFVDVELRDGGVGASEQLIEALQPFCEHLVHFGSYLSSD
HCCCHHHHHCCCCHHHHCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
LELD
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]