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The map label for this gene is tyrA [H]

Identifier: 124023987

GI number: 124023987

Start: 2025487

End: 2026431

Strand: Reverse

Name: tyrA [H]

Synonym: P9303_22941

Alternate gene names: 124023987

Gene position: 2026431-2025487 (Counterclockwise)

Preceding gene: 124023990

Following gene: 124023985

Centisome position: 75.54

GC content: 55.56

Gene sequence:

>945_bases
ATGGACTGCAGTGCGAGAACCGAAGGGATGGAGCAGAACAAAAAAACATCACTTTGCGCTGGAGTCGTAGGGCTTGGGCT
GATTGGTGGCTCCTTGGGATTGGATCTGCAGGCGCTTGGTTGGAAGGTCAATGGTCTGGTGCATCGTTCCAGTACCGCTG
ATAGGGCTCGCGCTAGGGGTTTGGCTCACTTGGTGAGCACCGATCCGGGCATTCTCGCGGATTGTGATTTGGTGATCCTG
GCGTTGCCTTTGGCTCAGCTGCTCAATCCAGATCCGAATCTCCTAAAGGCTTTGCCTACAGCTGCTGTGGTAACTGATGT
GGGTTCAGTGAAGATGCCTGTTTTAGAGCTCTGGCGCGACCTACACCCCCGCTTTGTGGCTAGCCATCCCATGGCAGGCA
CCGCTGAAGCAGGAGTGGAAGCAGGGCTGCGGGGCTTATTTCAGCAACGTCCTTGGGTAGCGACACCTGACAATCAAACA
GACCTTGAGGCGCTCGAGTTGGTGCGTCGATTTGCGGTGTCTTTGGGCAGTCAATGGTTTACGGCGGATGCAGCTAACCA
TGATCAAGCGGTGGCGCTGATTTCCCACCTGCCTGTGCTGGTGAGTGCTGCGTTGCTACGAACAGTGGGTGAGGAGCGTG
ATCCTGCTGTTCGCGAACTCGCCAGAGTGCTGTCTTCTAGTGGTTTTGCTGATACCACCAGGGTGGGTGGTGGTAATCCC
CAGTTGGGAACATCTATGGCTGAGAGCAACACCGCAGCGATCTTGCGTGGTTTGGCTGCTTATCGCTGGAGCTTGGAGCA
GCTTGAGGAGGCCGTTTTGAATGGGCACTGGTCGCAGTTAAAGGCTGAATTGGAACGTTCCCAGGCATTGCGACCCAGCT
TTCTTGTTGCTGCCAACAACGACCTCAATTCGCCACCCGTAACTGATGACCTCGCTGAGCCATGA

Upstream 100 bases:

>100_bases
GAGCAGGTGCTTGAGCTGCTGATGGCTGCGGGCTTCGAGCATTGCGAGAGCCTAGGAAGCCGTAAACCCGAGAAAGCTCC
ATGTTGATTGGTCGATCAAC

Downstream 100 bases:

>100_bases
GCTGGCGACAGGTCATGAGTGCCGAGATGCTCACCCCTGCAGTACCTTCACCAGGGTGAATTGAGTCGCCACAGAGCCAG
AGCCCTCGCATGGGAGTTCG

Product: arogenate dehydrogenase

Products: NA

Alternate protein names: Arogenate dehydrogenase; ADH; Cyclohexadienyl dehydrogenase; Prephenate dehydrogenase; PDH [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MDCSARTEGMEQNKKTSLCAGVVGLGLIGGSLGLDLQALGWKVNGLVHRSSTADRARARGLAHLVSTDPGILADCDLVIL
ALPLAQLLNPDPNLLKALPTAAVVTDVGSVKMPVLELWRDLHPRFVASHPMAGTAEAGVEAGLRGLFQQRPWVATPDNQT
DLEALELVRRFAVSLGSQWFTADAANHDQAVALISHLPVLVSAALLRTVGEERDPAVRELARVLSSSGFADTTRVGGGNP
QLGTSMAESNTAAILRGLAAYRWSLEQLEEAVLNGHWSQLKAELERSQALRPSFLVAANNDLNSPPVTDDLAEP

Sequences:

>Translated_314_residues
MDCSARTEGMEQNKKTSLCAGVVGLGLIGGSLGLDLQALGWKVNGLVHRSSTADRARARGLAHLVSTDPGILADCDLVIL
ALPLAQLLNPDPNLLKALPTAAVVTDVGSVKMPVLELWRDLHPRFVASHPMAGTAEAGVEAGLRGLFQQRPWVATPDNQT
DLEALELVRRFAVSLGSQWFTADAANHDQAVALISHLPVLVSAALLRTVGEERDPAVRELARVLSSSGFADTTRVGGGNP
QLGTSMAESNTAAILRGLAAYRWSLEQLEEAVLNGHWSQLKAELERSQALRPSFLVAANNDLNSPPVTDDLAEP
>Mature_314_residues
MDCSARTEGMEQNKKTSLCAGVVGLGLIGGSLGLDLQALGWKVNGLVHRSSTADRARARGLAHLVSTDPGILADCDLVIL
ALPLAQLLNPDPNLLKALPTAAVVTDVGSVKMPVLELWRDLHPRFVASHPMAGTAEAGVEAGLRGLFQQRPWVATPDNQT
DLEALELVRRFAVSLGSQWFTADAANHDQAVALISHLPVLVSAALLRTVGEERDPAVRELARVLSSSGFADTTRVGGGNP
QLGTSMAESNTAAILRGLAAYRWSLEQLEEAVLNGHWSQLKAELERSQALRPSFLVAANNDLNSPPVTDDLAEP

Specific function: Is competent to function as either prephenate dehydrogenase or as arogenate dehydrogenase [H]

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate/arogenate dehydrogenase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR016040
- InterPro:   IPR003099 [H]

Pfam domain/function: PF02153 PDH [H]

EC number: =1.3.1.43; =1.3.1.12 [H]

Molecular weight: Translated: 33344; Mature: 33344

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDCSARTEGMEQNKKTSLCAGVVGLGLIGGSLGLDLQALGWKVNGLVHRSSTADRARARG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCEEEHHEEECCCHHHHHHHHH
LAHLVSTDPGILADCDLVILALPLAQLLNPDPNLLKALPTAAVVTDVGSVKMPVLELWRD
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LHPRFVASHPMAGTAEAGVEAGLRGLFQQRPWVATPDNQTDLEALELVRRFAVSLGSQWF
HCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCE
TADAANHDQAVALISHLPVLVSAALLRTVGEERDPAVRELARVLSSSGFADTTRVGGGNP
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
QLGTSMAESNTAAILRGLAAYRWSLEQLEEAVLNGHWSQLKAELERSQALRPSFLVAANN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECC
DLNSPPVTDDLAEP
CCCCCCCCCCCCCC
>Mature Secondary Structure
MDCSARTEGMEQNKKTSLCAGVVGLGLIGGSLGLDLQALGWKVNGLVHRSSTADRARARG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCEEEHHEEECCCHHHHHHHHH
LAHLVSTDPGILADCDLVILALPLAQLLNPDPNLLKALPTAAVVTDVGSVKMPVLELWRD
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LHPRFVASHPMAGTAEAGVEAGLRGLFQQRPWVATPDNQTDLEALELVRRFAVSLGSQWF
HCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCE
TADAANHDQAVALISHLPVLVSAALLRTVGEERDPAVRELARVLSSSGFADTTRVGGGNP
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
QLGTSMAESNTAAILRGLAAYRWSLEQLEEAVLNGHWSQLKAELERSQALRPSFLVAANN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECC
DLNSPPVTDDLAEP
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7916685 [H]