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The map label for this gene is ho1 [H]

Identifier: 124023934

GI number: 124023934

Start: 1982773

End: 1983492

Strand: Direct

Name: ho1 [H]

Synonym: P9303_22411

Alternate gene names: 124023934

Gene position: 1982773-1983492 (Clockwise)

Preceding gene: 124023933

Following gene: 124023935

Centisome position: 73.91

GC content: 54.17

Gene sequence:

>720_bases
TTGGCGGTAGCCCTTGCGAGCCAATTGAGAGAAGGCACCAAGGCCGCCCACACGATGGCCGAAAACACTGGTTTCGTGAG
CTGTTTCCTTAAAGGTGTGGTTGATCAGTCCAGTTATCGCATGCTGGTGGCTGATCTCTATTTCGTCTACTCCGCATTGG
AAGCAGAAATCGGCAAGCTGCGTGAGCAAAAGCATCCGGTGGTGGCACCTGTTGGCTTCCCCGAGCTCAATCGCTGCGAG
GCCTTAGAACAAGATTTGATTTTTTATTTCGGCAGCAACTGGCGCAATCTGGCCAAGGCAACGCTGGCGGCTGAGGAGTA
TGTGGCCCGTATTCACACGTTGGCTCAGGAGTCGCCTGAGTTACTGGTGGCTCATCACTACACCCGCTATCTCGGGGACC
TTTCAGGCGGTCAGATTCTCAAGACCATCGCCCAGAAGGCCATGAAGCTAGGGGGCAATGACGGCGTGCGTTTTTATATC
TTTGATGACATTGAAGACACCAAAGCCTTCAAGACTCTGTACAGCGCCACCCTTGATAGCCTGCCGATCAATCAGCAGAC
CGCCGAGCGCATGGTCGAGGAGGCAAATATGGCCTTTCACTGCAATATGGCCATGTTCAAGGAGTTGGAAGGCAACCTAG
TGGCTGCAATTGGAAAGGTCCTGTTTGGATTCCTCACGAGCCGCCAACGAGGCGGCAGCACTGAGGATGCGGTGGCCTAA

Upstream 100 bases:

>100_bases
GCCGTTGAATCCTGTTCAAGTGCGAATCCTTCTTTTAAGGTCTTACTGAAACTGCCATTTAGCCTCCTAGGGTCAATCAA
GACATCCGACTTCAAGCACC

Downstream 100 bases:

>100_bases
GAGGAAAGCAAGAGGTTGACGGAGAATCAACGCCTTCAACTGGTCAACACTTTCAACCTGGCTGAGGATGAAATGCTTGC
GATCACCAGTCCCTATAAGA

Product: Heme oxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MAVALASQLREGTKAAHTMAENTGFVSCFLKGVVDQSSYRMLVADLYFVYSALEAEIGKLREQKHPVVAPVGFPELNRCE
ALEQDLIFYFGSNWRNLAKATLAAEEYVARIHTLAQESPELLVAHHYTRYLGDLSGGQILKTIAQKAMKLGGNDGVRFYI
FDDIEDTKAFKTLYSATLDSLPINQQTAERMVEEANMAFHCNMAMFKELEGNLVAAIGKVLFGFLTSRQRGGSTEDAVA

Sequences:

>Translated_239_residues
MAVALASQLREGTKAAHTMAENTGFVSCFLKGVVDQSSYRMLVADLYFVYSALEAEIGKLREQKHPVVAPVGFPELNRCE
ALEQDLIFYFGSNWRNLAKATLAAEEYVARIHTLAQESPELLVAHHYTRYLGDLSGGQILKTIAQKAMKLGGNDGVRFYI
FDDIEDTKAFKTLYSATLDSLPINQQTAERMVEEANMAFHCNMAMFKELEGNLVAAIGKVLFGFLTSRQRGGSTEDAVA
>Mature_238_residues
AVALASQLREGTKAAHTMAENTGFVSCFLKGVVDQSSYRMLVADLYFVYSALEAEIGKLREQKHPVVAPVGFPELNRCEA
LEQDLIFYFGSNWRNLAKATLAAEEYVARIHTLAQESPELLVAHHYTRYLGDLSGGQILKTIAQKAMKLGGNDGVRFYIF
DDIEDTKAFKTLYSATLDSLPINQQTAERMVEEANMAFHCNMAMFKELEGNLVAAIGKVLFGFLTSRQRGGSTEDAVA

Specific function: Catalyzes the opening of the heme ring with the release of iron. Key enzyme in the synthesis of the chromophoric part of the photosynthetic antennae [H]

COG id: COG5398

COG function: function code P; Heme oxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme oxygenase family [H]

Homologues:

Organism=Homo sapiens, GI187761311, Length=208, Percent_Identity=50, Blast_Score=214, Evalue=5e-56,
Organism=Homo sapiens, GI187761309, Length=208, Percent_Identity=50, Blast_Score=214, Evalue=5e-56,
Organism=Homo sapiens, GI187761307, Length=208, Percent_Identity=50, Blast_Score=214, Evalue=5e-56,
Organism=Homo sapiens, GI8051608, Length=208, Percent_Identity=50, Blast_Score=214, Evalue=5e-56,
Organism=Homo sapiens, GI4504437, Length=212, Percent_Identity=46.2264150943396, Blast_Score=192, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002051
- InterPro:   IPR016053
- InterPro:   IPR016084
- InterPro:   IPR018207 [H]

Pfam domain/function: PF01126 Heme_oxygenase [H]

EC number: =1.14.99.3 [H]

Molecular weight: Translated: 26431; Mature: 26299

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00593 HEME_OXYGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVALASQLREGTKAAHTMAENTGFVSCFLKGVVDQSSYRMLVADLYFVYSALEAEIGKL
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
REQKHPVVAPVGFPELNRCEALEQDLIFYFGSNWRNLAKATLAAEEYVARIHTLAQESPE
HHHCCCEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
LLVAHHYTRYLGDLSGGQILKTIAQKAMKLGGNDGVRFYIFDDIEDTKAFKTLYSATLDS
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHC
LPINQQTAERMVEEANMAFHCNMAMFKELEGNLVAAIGKVLFGFLTSRQRGGSTEDAVA
CCCCHHHHHHHHHHCCCEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AVALASQLREGTKAAHTMAENTGFVSCFLKGVVDQSSYRMLVADLYFVYSALEAEIGKL
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
REQKHPVVAPVGFPELNRCEALEQDLIFYFGSNWRNLAKATLAAEEYVARIHTLAQESPE
HHHCCCEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
LLVAHHYTRYLGDLSGGQILKTIAQKAMKLGGNDGVRFYIFDDIEDTKAFKTLYSATLDS
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHC
LPINQQTAERMVEEANMAFHCNMAMFKELEGNLVAAIGKVLFGFLTSRQRGGSTEDAVA
CCCCHHHHHHHHHHCCCEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]