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The map label for this gene is nrdR

Identifier: 124023908

GI number: 124023908

Start: 1965293

End: 1965769

Strand: Direct

Name: nrdR

Synonym: P9303_22151

Alternate gene names: 124023908

Gene position: 1965293-1965769 (Clockwise)

Preceding gene: 124023907

Following gene: 124023909

Centisome position: 73.26

GC content: 48.22

Gene sequence:

>477_bases
ATGCAATGCCCCTCCTGCCAAAACACTGATAGTCGGGTACTTGAATCCCGCGCTGCTGATGCCGGGCGAAGTGTAAGAAG
GCGCCGTGAATGCTTACATTGTGACTTTCGCTTCACGACCTACGAACGCGTCGAAACTGTTCCAATCACAGTTTTGAAGC
GTAATGGCAATAGGGAGACTTTCAATCGCAGTAAAATCCTTAATGGCCTTACTATGGCCTGTCAAAAAACCGGTCTCGAG
CAAGACAGACTTGAGTCAATGGTGAACGAACTTGAACTGCAACTTCAGCAACGAAGTGGGCGTGAAGTGAATAGTGCTGA
AATCGGCGAAATGGTTTTGGACCAACTATCTGAAATGAGCGAGGTCGCTTACGTACGCTTTGCGTCGGTATATCGTCATT
TCCGTGGAATTAATGATTTCGTAGCAGCACTTGAAGGCATTCATGCCAACAAGGAACAGCTCGCAGCCGTTCGCTGA

Upstream 100 bases:

>100_bases
GATTTACGGCAGTAAAGCCTGAGAATGCAGTTCAACAGGTCCTTCTCAAGGCTCGAATTACTGTCTAGACTTAGTTCACT
AAATTTGGAGTCTTACGGGC

Downstream 100 bases:

>100_bases
GAATAAGGAGTCAATCTGTAGAGTGATCCATTAATTCCGAAAGGTCGGCGGGCCACTCGGATTTCCTTGCGCACTGCCAT
AGGGCAGACCGCCATCCAAC

Product: NrdR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MQCPSCQNTDSRVLESRAADAGRSVRRRRECLHCDFRFTTYERVETVPITVLKRNGNRETFNRSKILNGLTMACQKTGLE
QDRLESMVNELELQLQQRSGREVNSAEIGEMVLDQLSEMSEVAYVRFASVYRHFRGINDFVAALEGIHANKEQLAAVR

Sequences:

>Translated_158_residues
MQCPSCQNTDSRVLESRAADAGRSVRRRRECLHCDFRFTTYERVETVPITVLKRNGNRETFNRSKILNGLTMACQKTGLE
QDRLESMVNELELQLQQRSGREVNSAEIGEMVLDQLSEMSEVAYVRFASVYRHFRGINDFVAALEGIHANKEQLAAVR
>Mature_158_residues
MQCPSCQNTDSRVLESRAADAGRSVRRRRECLHCDFRFTTYERVETVPITVLKRNGNRETFNRSKILNGLTMACQKTGLE
QDRLESMVNELELQLQQRSGREVNSAEIGEMVLDQLSEMSEVAYVRFASVYRHFRGINDFVAALEGIHANKEQLAAVR

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=148, Percent_Identity=44.5945945945946, Blast_Score=126, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_PROM3 (A2CBU0)

Other databases:

- EMBL:   CP000554
- RefSeq:   YP_001018215.1
- STRING:   A2CBU0
- GeneID:   4778050
- GenomeReviews:   CP000554_GR
- KEGG:   pmf:P9303_22151
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 18100; Mature: 18100

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQCPSCQNTDSRVLESRAADAGRSVRRRRECLHCDFRFTTYERVETVPITVLKRNGNRET
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEECCCCCHH
FNRSKILNGLTMACQKTGLEQDRLESMVNELELQLQQRSGREVNSAEIGEMVLDQLSEMS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
EVAYVRFASVYRHFRGINDFVAALEGIHANKEQLAAVR
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHCCC
>Mature Secondary Structure
MQCPSCQNTDSRVLESRAADAGRSVRRRRECLHCDFRFTTYERVETVPITVLKRNGNRET
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEECCCCCHH
FNRSKILNGLTMACQKTGLEQDRLESMVNELELQLQQRSGREVNSAEIGEMVLDQLSEMS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
EVAYVRFASVYRHFRGINDFVAALEGIHANKEQLAAVR
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA