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The map label for this gene is sua5 [H]

Identifier: 124023897

GI number: 124023897

Start: 1958892

End: 1959482

Strand: Reverse

Name: sua5 [H]

Synonym: P9303_22041

Alternate gene names: 124023897

Gene position: 1959482-1958892 (Counterclockwise)

Preceding gene: 124023898

Following gene: 124023892

Centisome position: 73.04

GC content: 57.7

Gene sequence:

>591_bases
ATGGCACTTCTGCCTTCGGCTGTTCTTGACGCCAGTGCCTTGGCATCCAGATTGCATGCTGGTTCAGCGGCATTGTTGCC
CACAGACACCTTGCCAGCTTTGGCGGCCGCTCCTGTTCATGCTGCACAGTTGTGGACCATGAAGCAGAGGTCGGCCGACA
AACCTCTGATCCTGATGGCAGCGACTCCTGAAGAGTTACTTGCGCATGTTTCGCCGCTTGCTTTGGAGGATGCCTGGTCG
ATGGCCAGGCGCTATTGGCCCGGGGCCCTCACCTTGGTTGTACCGGCTTCGGGTGTGCTTGTTGAGGCTCTTAATCCTGG
AGCTTTCACGCTTGGGTTGCGAGTACCGGATTGTGGAGTGATTAGGTGTTTGCTGAAGCAGAGCGGGCCGCTAGCTACCA
CGAGCGCGAATTTGTCTGGTGCTGCGCCCACGTTCTCTGCAGATGCTGCTCATACTTGTTTCCCAGGATTGCCATTGTTG
GGGCCATTGCCATGGCCGACGCCTTCTGGTTTGGCCAGTACGGTGGTGGCTTGGCAAGGGAGCGGGCGTTGGCATGAGTT
ACGACGTGGTGCAGTGGTGCTTGAGCTTTGA

Upstream 100 bases:

>100_bases
CGTCAGCAGGGTTTGGAGAATGTGGAGTACAAGTCAGATTTACTGGGGGTAAGGCGCTTTGCCATTGCTCGGCATCCTGA
ACATCACGACTCTTTGAACC

Downstream 100 bases:

>100_bases
ATGAATCGCGCGATCAAGAGAGCTTGGCTATTCCAATGGCTAACCAAGGTCGGATAAAAGGTGTATTGCAGAGATGACTT
CAGTGATGTAAAAAACTTCT

Product: translation factor (SUA5)

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MALLPSAVLDASALASRLHAGSAALLPTDTLPALAAAPVHAAQLWTMKQRSADKPLILMAATPEELLAHVSPLALEDAWS
MARRYWPGALTLVVPASGVLVEALNPGAFTLGLRVPDCGVIRCLLKQSGPLATTSANLSGAAPTFSADAAHTCFPGLPLL
GPLPWPTPSGLASTVVAWQGSGRWHELRRGAVVLEL

Sequences:

>Translated_196_residues
MALLPSAVLDASALASRLHAGSAALLPTDTLPALAAAPVHAAQLWTMKQRSADKPLILMAATPEELLAHVSPLALEDAWS
MARRYWPGALTLVVPASGVLVEALNPGAFTLGLRVPDCGVIRCLLKQSGPLATTSANLSGAAPTFSADAAHTCFPGLPLL
GPLPWPTPSGLASTVVAWQGSGRWHELRRGAVVLEL
>Mature_195_residues
ALLPSAVLDASALASRLHAGSAALLPTDTLPALAAAPVHAAQLWTMKQRSADKPLILMAATPEELLAHVSPLALEDAWSM
ARRYWPGALTLVVPASGVLVEALNPGAFTLGLRVPDCGVIRCLLKQSGPLATTSANLSGAAPTFSADAAHTCFPGLPLLG
PLPWPTPSGLASTVVAWQGSGRWHELRRGAVVLEL

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI17537239, Length=174, Percent_Identity=32.183908045977, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI78707274, Length=184, Percent_Identity=30.4347826086957, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 20270; Mature: 20139

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLPSAVLDASALASRLHAGSAALLPTDTLPALAAAPVHAAQLWTMKQRSADKPLILMA
CCCCCHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHCCCHHHHHHHHHHHCCCCCEEEEE
ATPEELLAHVSPLALEDAWSMARRYWPGALTLVVPASGVLVEALNPGAFTLGLRVPDCGV
CCHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCCCEEEEEEECCCHHH
IRCLLKQSGPLATTSANLSGAAPTFSADAAHTCFPGLPLLGPLPWPTPSGLASTVVAWQG
HHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEEECC
SGRWHELRRGAVVLEL
CCCHHHHHCCEEEEEC
>Mature Secondary Structure 
ALLPSAVLDASALASRLHAGSAALLPTDTLPALAAAPVHAAQLWTMKQRSADKPLILMA
CCCCHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHCCCHHHHHHHHHHHCCCCCEEEEE
ATPEELLAHVSPLALEDAWSMARRYWPGALTLVVPASGVLVEALNPGAFTLGLRVPDCGV
CCHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCCCEEEEEEECCCHHH
IRCLLKQSGPLATTSANLSGAAPTFSADAAHTCFPGLPLLGPLPWPTPSGLASTVVAWQG
HHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEEECC
SGRWHELRRGAVVLEL
CCCHHHHHCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]