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The map label for this gene is mtnD [H]

Identifier: 124023853

GI number: 124023853

Start: 1919014

End: 1919670

Strand: Direct

Name: mtnD [H]

Synonym: P9303_21601

Alternate gene names: 124023853

Gene position: 1919014-1919670 (Clockwise)

Preceding gene: 124023850

Following gene: 124023859

Centisome position: 71.53

GC content: 55.4

Gene sequence:

>657_bases
TTGAAACAGCAGGGCTCGACAAAGCCGAACGAAACATTCAGCCGTCGTTCTAAGACGCCACGATCAAGATGGCTGCAAAG
ACCCCTTCAACCTCTGGGAATGAGTCGCCTCAGCATCCACCCCGAAGGCAACACCAACGCCACAAGCCCGGCGGAACCCT
TATTGGAGAGCGATGATCCTGCAGTGATCAAAGCCGAGCTGGCCAAACGGGGCATTGAATTCCAGCATTGGCCAGCCAAA
GTCAAGCTCCATCAGAACTCAATCGAGTCAGACATCCTTGCGGCCTACGCCGTCGAGATCGCCCGAGTGCAGGCTGATGG
CCGTTACCCCACGGTGGATGCAATCCGAATCACGCCAGACCACCCCGATCGTGAAGCACTGCGCCAAAAATTCTTAGCCG
AACACACCCATGCCGAAGACGAGGTTCGCTTCTTTGTAGAAGGCCGTGGCTTGTTCTGCTTACACATCGGCGCTGAAGTG
CTGCAAGTGCTGTGCGAACAAAACGACTGCATCAACGTGCCTGCCGGAACTCGCCATTGGTTCGATATGGGCAGCAAGCC
ACAGTTTTGTGCTGTGCGCTTCTTCGATAACCCAGAAGGCTGGATTGCAAGCTTCACAGGGGATGCGATCGCCGAGAGAT
TCGCCAAACTGCCATAA

Upstream 100 bases:

>100_bases
GGATAGGCCACAACAGTGGCCGCTTCAATCGCCTCAATGGCAGCCAGGGTCAACAGGGCAGGATCACCAGGGCCCACCCC
GACCAGGATGAGAGCTGTAG

Downstream 100 bases:

>100_bases
AGCTGATCGGCTTCAGCTATGCATGCGTGGCTGAGGATGCAAGTTGGCGAGGATCCCTGCCTCCACCGCTGCCAACTCCT
GCAAACGAGCAATGATCAGC

Product: methionine salvage pathway enzyme E-2/E-2'-like protein

Products: NA

Alternate protein names: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; DHK-MTPene dioxygenase; Acireductone dioxygenase (Fe(2+)-requiring); ARD'; Fe-ARD; Acireductone dioxygenase (Ni(2+)-requiring); ARD; Ni-ARD [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MKQQGSTKPNETFSRRSKTPRSRWLQRPLQPLGMSRLSIHPEGNTNATSPAEPLLESDDPAVIKAELAKRGIEFQHWPAK
VKLHQNSIESDILAAYAVEIARVQADGRYPTVDAIRITPDHPDREALRQKFLAEHTHAEDEVRFFVEGRGLFCLHIGAEV
LQVLCEQNDCINVPAGTRHWFDMGSKPQFCAVRFFDNPEGWIASFTGDAIAERFAKLP

Sequences:

>Translated_218_residues
MKQQGSTKPNETFSRRSKTPRSRWLQRPLQPLGMSRLSIHPEGNTNATSPAEPLLESDDPAVIKAELAKRGIEFQHWPAK
VKLHQNSIESDILAAYAVEIARVQADGRYPTVDAIRITPDHPDREALRQKFLAEHTHAEDEVRFFVEGRGLFCLHIGAEV
LQVLCEQNDCINVPAGTRHWFDMGSKPQFCAVRFFDNPEGWIASFTGDAIAERFAKLP
>Mature_218_residues
MKQQGSTKPNETFSRRSKTPRSRWLQRPLQPLGMSRLSIHPEGNTNATSPAEPLLESDDPAVIKAELAKRGIEFQHWPAK
VKLHQNSIESDILAAYAVEIARVQADGRYPTVDAIRITPDHPDREALRQKFLAEHTHAEDEVRFFVEGRGLFCLHIGAEV
LQVLCEQNDCINVPAGTRHWFDMGSKPQFCAVRFFDNPEGWIASFTGDAIAERFAKLP

Specific function: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- me

COG id: COG1791

COG function: function code S; Uncharacterized conserved protein, contains double-stranded beta-helix domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acireductone dioxygenase (ARD) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004313
- InterPro:   IPR011051
- InterPro:   IPR014710 [H]

Pfam domain/function: PF03079 ARD [H]

EC number: =1.13.11.54; =1.13.11.53 [H]

Molecular weight: Translated: 24597; Mature: 24597

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQQGSTKPNETFSRRSKTPRSRWLQRPLQPLGMSRLSIHPEGNTNATSPAEPLLESDDP
CCCCCCCCCCHHHHHHCCCHHHHHHHCCHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCC
AVIKAELAKRGIEFQHWPAKVKLHQNSIESDILAAYAVEIARVQADGRYPTVDAIRITPD
CEEHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHEECCCCCCCCEEEEECCC
HPDREALRQKFLAEHTHAEDEVRFFVEGRGLFCLHIGAEVLQVLCEQNDCINVPAGTRHW
CCCHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEHHHHHHHHHHCCCCEEECCCCCCHH
FDMGSKPQFCAVRFFDNPEGWIASFTGDAIAERFAKLP
HCCCCCCCEEEEEEECCCCCEEEECCHHHHHHHHHCCC
>Mature Secondary Structure
MKQQGSTKPNETFSRRSKTPRSRWLQRPLQPLGMSRLSIHPEGNTNATSPAEPLLESDDP
CCCCCCCCCCHHHHHHCCCHHHHHHHCCHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCC
AVIKAELAKRGIEFQHWPAKVKLHQNSIESDILAAYAVEIARVQADGRYPTVDAIRITPD
CEEHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHEECCCCCCCCEEEEECCC
HPDREALRQKFLAEHTHAEDEVRFFVEGRGLFCLHIGAEVLQVLCEQNDCINVPAGTRHW
CCCHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEHHHHHHHHHHCCCCEEECCCCCCHH
FDMGSKPQFCAVRFFDNPEGWIASFTGDAIAERFAKLP
HCCCCCCCEEEEEEECCCCCEEEECCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA