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The map label for this gene is engA [H]

Identifier: 124023844

GI number: 124023844

Start: 1912683

End: 1914068

Strand: Reverse

Name: engA [H]

Synonym: P9303_21511

Alternate gene names: 124023844

Gene position: 1914068-1912683 (Counterclockwise)

Preceding gene: 124023845

Following gene: 124023843

Centisome position: 71.35

GC content: 55.7

Gene sequence:

>1386_bases
TTGCAAGGATTCAGCCAAGTGGCGCGTCCGATTGTCGCCATCATCGGTCGCCCCAACGTCGGCAAGTCCACGCTGGTGAA
TCGACTTTGTCGCAGTCGCGAGGCGATCGTTGATGACAAGCCTGGCGTCACCCGCGATCGCACCTATCAGGATGGTTTCT
GGGGAGATCGTGAGTTCAAGGTGGTCGACACCGGTGGCTTGGTCTTTGATGACGACAGTGAGTTTTTGCCCGAGATTCGC
GAACAGGCCAACTTGGCTCTGGCGGAAGCCTCTGTAGCACTTGTGATTGTTGATGGCCAGCAGGGTGTTACGGCTGCAGA
TGAGTCGATCGCTGAATGGTTACGTATGCAACCATGTCCCACTCTGGTGGCAGTGAATAAGTGCGAATCGCCAGATCAGG
GTTTGGCGATGGCGGCTGAGTTTTGGCGTCTTGGCCTAGGAGAGCCTTTCCCGATTTCTGCAATCCATGGAGCTGGCACA
GGCGATCTGCTCGATCGTGTGCTCTCTCTTCTGCCGCCAAAGCATGAGGAGGCAGAAGAGGATGAACCGATTCAGATGGC
CATTATTGGCAGGCCCAATGTGGGTAAATCAAGCCTGCTCAATGCCATTTGTGGCGAGCCACGCGCGATTGTTAGCCCGA
TTCGTGGCACCACCCGCGACACCATCGATACACGTCTTGAACGTGAAGGCCATCCTTGGAGACTGATCGATACAGCTGGC
ATCAGGCGTCGGCGCAGTGTGAATTACGGCCCTGAGTTTTTTGGCATCAACCGGAGTTTTAAGGCGATTGAACGCAGCGA
TGTGTGTGTGTTGGTGATTGATGCCCTTGATGGGGTCACAGAGCAGGATCAGCGCCTAGCCGGCAGGATTGAAGATGATG
GCCGCGCATGCGTGCTGGTGGTGAACAAATGGGATGCGGTCGAGAAAGATAGTCACACCATGCCGATGGTTGAAAAAGAG
CTGCGCGCCAAGCTTTACTTTCTCGATTGGGCCACGATGTTGTTCACCTCTGCACTCACTGGGCAGCGGGTGGAAAGTAT
CTTTGCTTTGGCCGCCTTGGCGGTTGAGCAGCACCGTCGTCGGGTGAGCACCTCGGTGGTGAATGAGGTGTTGAAGGAAG
CCTTGAGTTGGCGCAGTCCACCCACCTCCCGTGGGGGTCGCCAGGGACGTCTTTATTACGGCACTCAAGTGGCTAGCAGG
CCGCCTAGTTTCACGTTGTTTGTCAATGACCCGAAGTTGTTTGGCGATACCTACCGCCGCTATGTGGAACGGCAGTTACG
AGAAGGGCTTGGTTTTGATGGCACTCCTTTGAAGCTGTTTTGGCGTGGTAAGCAGCAACGGGCTGCCGAACGCGACCTGG
CTCGTCAGCAGAACCGTTTGGGATAA

Upstream 100 bases:

>100_bases
CCGTTAAAGGGCATCCTGGCGATCCGATTGTTGAGTGAATCCTGATTGCAGAGCTGCATCACCCCGTCTCGGTTTGATGC
CTCTGTAGGGTCGAGAATGA

Downstream 100 bases:

>100_bases
GTCATGGACTGGTTGCGTCAGCTTCCGATCGGGCAGTACGTGGCTGGCAACTCCGGTTGGTTGCGTCGTCTCGATCCCCG
TTTGAAGCTGGCTTGGGTGT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MQGFSQVARPIVAIIGRPNVGKSTLVNRLCRSREAIVDDKPGVTRDRTYQDGFWGDREFKVVDTGGLVFDDDSEFLPEIR
EQANLALAEASVALVIVDGQQGVTAADESIAEWLRMQPCPTLVAVNKCESPDQGLAMAAEFWRLGLGEPFPISAIHGAGT
GDLLDRVLSLLPPKHEEAEEDEPIQMAIIGRPNVGKSSLLNAICGEPRAIVSPIRGTTRDTIDTRLEREGHPWRLIDTAG
IRRRRSVNYGPEFFGINRSFKAIERSDVCVLVIDALDGVTEQDQRLAGRIEDDGRACVLVVNKWDAVEKDSHTMPMVEKE
LRAKLYFLDWATMLFTSALTGQRVESIFALAALAVEQHRRRVSTSVVNEVLKEALSWRSPPTSRGGRQGRLYYGTQVASR
PPSFTLFVNDPKLFGDTYRRYVERQLREGLGFDGTPLKLFWRGKQQRAAERDLARQQNRLG

Sequences:

>Translated_461_residues
MQGFSQVARPIVAIIGRPNVGKSTLVNRLCRSREAIVDDKPGVTRDRTYQDGFWGDREFKVVDTGGLVFDDDSEFLPEIR
EQANLALAEASVALVIVDGQQGVTAADESIAEWLRMQPCPTLVAVNKCESPDQGLAMAAEFWRLGLGEPFPISAIHGAGT
GDLLDRVLSLLPPKHEEAEEDEPIQMAIIGRPNVGKSSLLNAICGEPRAIVSPIRGTTRDTIDTRLEREGHPWRLIDTAG
IRRRRSVNYGPEFFGINRSFKAIERSDVCVLVIDALDGVTEQDQRLAGRIEDDGRACVLVVNKWDAVEKDSHTMPMVEKE
LRAKLYFLDWATMLFTSALTGQRVESIFALAALAVEQHRRRVSTSVVNEVLKEALSWRSPPTSRGGRQGRLYYGTQVASR
PPSFTLFVNDPKLFGDTYRRYVERQLREGLGFDGTPLKLFWRGKQQRAAERDLARQQNRLG
>Mature_461_residues
MQGFSQVARPIVAIIGRPNVGKSTLVNRLCRSREAIVDDKPGVTRDRTYQDGFWGDREFKVVDTGGLVFDDDSEFLPEIR
EQANLALAEASVALVIVDGQQGVTAADESIAEWLRMQPCPTLVAVNKCESPDQGLAMAAEFWRLGLGEPFPISAIHGAGT
GDLLDRVLSLLPPKHEEAEEDEPIQMAIIGRPNVGKSSLLNAICGEPRAIVSPIRGTTRDTIDTRLEREGHPWRLIDTAG
IRRRRSVNYGPEFFGINRSFKAIERSDVCVLVIDALDGVTEQDQRLAGRIEDDGRACVLVVNKWDAVEKDSHTMPMVEKE
LRAKLYFLDWATMLFTSALTGQRVESIFALAALAVEQHRRRVSTSVVNEVLKEALSWRSPPTSRGGRQGRLYYGTQVASR
PPSFTLFVNDPKLFGDTYRRYVERQLREGLGFDGTPLKLFWRGKQQRAAERDLARQQNRLG

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Homo sapiens, GI193082991, Length=132, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI193082988, Length=132, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87082120, Length=476, Percent_Identity=39.9159663865546, Blast_Score=310, Evalue=9e-86,
Organism=Escherichia coli, GI2367268, Length=93, Percent_Identity=43.010752688172, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788919, Length=174, Percent_Identity=28.735632183908, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17507259, Length=91, Percent_Identity=42.8571428571429, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=166, Percent_Identity=31.9277108433735, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI45550813, Length=142, Percent_Identity=33.0985915492958, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 51456; Mature: 51456

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGFSQVARPIVAIIGRPNVGKSTLVNRLCRSREAIVDDKPGVTRDRTYQDGFWGDREFK
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEE
VVDTGGLVFDDDSEFLPEIREQANLALAEASVALVIVDGQQGVTAADESIAEWLRMQPCP
EEECCCEEECCCHHHHHHHHHHHHHEEEECCEEEEEEECCCCCCHHHHHHHHHHHCCCCC
TLVAVNKCESPDQGLAMAAEFWRLGLGEPFPISAIHGAGTGDLLDRVLSLLPPKHEEAEE
CEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCC
DEPIQMAIIGRPNVGKSSLLNAICGEPRAIVSPIRGTTRDTIDTRLEREGHPWRLIDTAG
CCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHCCCCCEEEEECCC
IRRRRSVNYGPEFFGINRSFKAIERSDVCVLVIDALDGVTEQDQRLAGRIEDDGRACVLV
CHHHCCCCCCCCEEECCCHHHHHCCCCEEEEEEECCCCCCHHHHHHHCCCCCCCCEEEEE
VNKWDAVEKDSHTMPMVEKELRAKLYFLDWATMLFTSALTGQRVESIFALAALAVEQHRR
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVSTSVVNEVLKEALSWRSPPTSRGGRQGRLYYGTQVASRPPSFTLFVNDPKLFGDTYRR
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCHHHHHHHHH
YVERQLREGLGFDGTPLKLFWRGKQQRAAERDLARQQNRLG
HHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQGFSQVARPIVAIIGRPNVGKSTLVNRLCRSREAIVDDKPGVTRDRTYQDGFWGDREFK
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEE
VVDTGGLVFDDDSEFLPEIREQANLALAEASVALVIVDGQQGVTAADESIAEWLRMQPCP
EEECCCEEECCCHHHHHHHHHHHHHEEEECCEEEEEEECCCCCCHHHHHHHHHHHCCCCC
TLVAVNKCESPDQGLAMAAEFWRLGLGEPFPISAIHGAGTGDLLDRVLSLLPPKHEEAEE
CEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCC
DEPIQMAIIGRPNVGKSSLLNAICGEPRAIVSPIRGTTRDTIDTRLEREGHPWRLIDTAG
CCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHCCCCCEEEEECCC
IRRRRSVNYGPEFFGINRSFKAIERSDVCVLVIDALDGVTEQDQRLAGRIEDDGRACVLV
CHHHCCCCCCCCEEECCCHHHHHCCCCEEEEEEECCCCCCHHHHHHHCCCCCCCCEEEEE
VNKWDAVEKDSHTMPMVEKELRAKLYFLDWATMLFTSALTGQRVESIFALAALAVEQHRR
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVSTSVVNEVLKEALSWRSPPTSRGGRQGRLYYGTQVASRPPSFTLFVNDPKLFGDTYRR
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCHHHHHHHHH
YVERQLREGLGFDGTPLKLFWRGKQQRAAERDLARQQNRLG
HHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]