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The map label for this gene is desA [H]

Identifier: 124023801

GI number: 124023801

Start: 1869188

End: 1870330

Strand: Direct

Name: desA [H]

Synonym: P9303_21081

Alternate gene names: 124023801

Gene position: 1869188-1870330 (Clockwise)

Preceding gene: 124023800

Following gene: 124023802

Centisome position: 69.68

GC content: 44.27

Gene sequence:

>1143_bases
ATGATGTCTGGCCTCAATGGAAAGGCGCTCAAGGTTTCCAAAGCGGATATACCTGATCTGGCTGCAATTAAGGCTGTTTT
GCCTCATCAATGCTTGAATTGCAGCACCAACACTTCCCTTGCTTATCTAGCCCAATCTCTGACGATACAGGTCATAGTAA
TTTCCATAGGGATGTCCATCCCTCTCAATGTGGAAATATTGCCTGTTTGGGTTCTCTACTGGCTTGTATCTGGCACAACA
GCAATGGGCTTATGGGTCATCGCACATGAATGCGGACACGGTGCATTTTCGAAAAATAGGAAACTAGAAACATTCGTTGG
CTATGTGTTGCATTCGATGCTTCTTGTTCCATATTTCTCATGGCAGCGTTCACATTTAGTTCACCATACTTATACGAACC
ATATCGCCAATGGTGAGACCCACGTGCCTTTAGTCATTCGTGGCAACGGAATTGATGAGCAGGCTGGTGGAGAAAAAGAT
ATTGCCATAGCAGGCAGATTAGGAAAAGTTCAATATGGTGTATTTCAGCTTGTGCTTCATCTGGTTTTTGGCTGGCCAGC
CTATTTGCTGACTGGGAAGACGGGAGGCCCAAAATATGGCCTATCGAATCACTTCTGGCCGATAGCACCTTTCTCTAGAA
AATTGTGGACAAAAAAATGGATAAATAAAGTCTGGCTTTCCGATTGGGGGATATGTCTGGCTCTGTTTGCATTGATTGCC
TGGAGCCTGCATGATGGCTTTGTTACTGTTTTTGCAATTTATTTAGCTCCTCTGTTAGTAGTCAATATCTGGCTAGTCAC
CTATACGTGGCTGCATCATACTGATACTGATGTTCCCCACCTTGGCGGTTCAGACTTCTCCCAATTGCGAGGTGCGTTCC
TATCGATTGATAGGCCATATGGAAAAGTAATTGATTTCCTCCATCACAAGATAGGCTCTACTCATGCCATTCATCACATA
GCACCTTGGATGCCTCATTACCATGCAGGCAAAGCCACTATTGCCCTAAAAAATGCTTTCCCAAAGGTATATCTTTACAA
TCAAACACCAATTCTTCAGGCTCTCTGGCTTATTTCTACTAACTGCATAGCTGTCACTCGGGAAGAGAACAGTGGACGCT
ATGTCTGGAAAAATCCTTGGTGA

Upstream 100 bases:

>100_bases
ATTATCATATCCAATGAGCCCTTACCAACCATAGTCATTGAAAGATCATTCAGAAAGCCATGAAAAAACATTTTTTAGAC
AAAAAGCTGCTAAAGGCATC

Downstream 100 bases:

>100_bases
GAGCACGAGGATCGAGGAAGATCCATTGACTGGTTCAATATCTATCCAGTCAGTTGTTTAATGATCATTTACAACCAATA
TCTATATTCACTCCATTAAA

Product: fatty acid desaturase, type 2

Products: NA

Alternate protein names: Delta(12)-desaturase [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MMSGLNGKALKVSKADIPDLAAIKAVLPHQCLNCSTNTSLAYLAQSLTIQVIVISIGMSIPLNVEILPVWVLYWLVSGTT
AMGLWVIAHECGHGAFSKNRKLETFVGYVLHSMLLVPYFSWQRSHLVHHTYTNHIANGETHVPLVIRGNGIDEQAGGEKD
IAIAGRLGKVQYGVFQLVLHLVFGWPAYLLTGKTGGPKYGLSNHFWPIAPFSRKLWTKKWINKVWLSDWGICLALFALIA
WSLHDGFVTVFAIYLAPLLVVNIWLVTYTWLHHTDTDVPHLGGSDFSQLRGAFLSIDRPYGKVIDFLHHKIGSTHAIHHI
APWMPHYHAGKATIALKNAFPKVYLYNQTPILQALWLISTNCIAVTREENSGRYVWKNPW

Sequences:

>Translated_380_residues
MMSGLNGKALKVSKADIPDLAAIKAVLPHQCLNCSTNTSLAYLAQSLTIQVIVISIGMSIPLNVEILPVWVLYWLVSGTT
AMGLWVIAHECGHGAFSKNRKLETFVGYVLHSMLLVPYFSWQRSHLVHHTYTNHIANGETHVPLVIRGNGIDEQAGGEKD
IAIAGRLGKVQYGVFQLVLHLVFGWPAYLLTGKTGGPKYGLSNHFWPIAPFSRKLWTKKWINKVWLSDWGICLALFALIA
WSLHDGFVTVFAIYLAPLLVVNIWLVTYTWLHHTDTDVPHLGGSDFSQLRGAFLSIDRPYGKVIDFLHHKIGSTHAIHHI
APWMPHYHAGKATIALKNAFPKVYLYNQTPILQALWLISTNCIAVTREENSGRYVWKNPW
>Mature_380_residues
MMSGLNGKALKVSKADIPDLAAIKAVLPHQCLNCSTNTSLAYLAQSLTIQVIVISIGMSIPLNVEILPVWVLYWLVSGTT
AMGLWVIAHECGHGAFSKNRKLETFVGYVLHSMLLVPYFSWQRSHLVHHTYTNHIANGETHVPLVIRGNGIDEQAGGEKD
IAIAGRLGKVQYGVFQLVLHLVFGWPAYLLTGKTGGPKYGLSNHFWPIAPFSRKLWTKKWINKVWLSDWGICLALFALIA
WSLHDGFVTVFAIYLAPLLVVNIWLVTYTWLHHTDTDVPHLGGSDFSQLRGAFLSIDRPYGKVIDFLHHKIGSTHAIHHI
APWMPHYHAGKATIALKNAFPKVYLYNQTPILQALWLISTNCIAVTREENSGRYVWKNPW

Specific function: Can introduce a second cis double bond at the Delta(12) position of fatty acid bound to membranes glycerolipids. This enzyme is involved in chilling tolerance because the phase transition temperature of lipids of cellular membranes depends on the degree o

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17542730, Length=341, Percent_Identity=30.2052785923754, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71999459, Length=328, Percent_Identity=28.6585365853659, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 42580; Mature: 42580

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSGLNGKALKVSKADIPDLAAIKAVLPHQCLNCSTNTSLAYLAQSLTIQVIVISIGMSI
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHEEEEEEEEECCCC
PLNVEILPVWVLYWLVSGTTAMGLWVIAHECGHGAFSKNRKLETFVGYVLHSMLLVPYFS
CCCEEHHHHHHHHHHHHCCHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
WQRSHLVHHTYTNHIANGETHVPLVIRGNGIDEQAGGEKDIAIAGRLGKVQYGVFQLVLH
CCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHH
LVFGWPAYLLTGKTGGPKYGLSNHFWPIAPFSRKLWTKKWINKVWLSDWGICLALFALIA
HHHCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
WSLHDGFVTVFAIYLAPLLVVNIWLVTYTWLHHTDTDVPHLGGSDFSQLRGAFLSIDRPY
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCHHHEECCCCH
GKVIDFLHHKIGSTHAIHHIAPWMPHYHAGKATIALKNAFPKVYLYNQTPILQALWLIST
HHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCEEEEEECCCCEEEEECCCHHHHHHHHHCC
NCIAVTREENSGRYVWKNPW
CEEEEEEECCCCEEEECCCC
>Mature Secondary Structure
MMSGLNGKALKVSKADIPDLAAIKAVLPHQCLNCSTNTSLAYLAQSLTIQVIVISIGMSI
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHEEEEEEEEECCCC
PLNVEILPVWVLYWLVSGTTAMGLWVIAHECGHGAFSKNRKLETFVGYVLHSMLLVPYFS
CCCEEHHHHHHHHHHHHCCHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
WQRSHLVHHTYTNHIANGETHVPLVIRGNGIDEQAGGEKDIAIAGRLGKVQYGVFQLVLH
CCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHH
LVFGWPAYLLTGKTGGPKYGLSNHFWPIAPFSRKLWTKKWINKVWLSDWGICLALFALIA
HHHCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
WSLHDGFVTVFAIYLAPLLVVNIWLVTYTWLHHTDTDVPHLGGSDFSQLRGAFLSIDRPY
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCHHHEECCCCH
GKVIDFLHHKIGSTHAIHHIAPWMPHYHAGKATIALKNAFPKVYLYNQTPILQALWLIST
HHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCEEEEEECCCCEEEEECCCHHHHHHHHHCC
NCIAVTREENSGRYVWKNPW
CEEEEEEECCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA