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The map label for this gene is smtA [C]

Identifier: 124023751

GI number: 124023751

Start: 1811084

End: 1813426

Strand: Reverse

Name: smtA [C]

Synonym: P9303_20571

Alternate gene names: 124023751

Gene position: 1813426-1811084 (Counterclockwise)

Preceding gene: 124023754

Following gene: 124023750

Centisome position: 67.6

GC content: 36.45

Gene sequence:

>2343_bases
ATGAAAGGATTTGGAGAAAAGAAGAAAATAAAAAATAAACAACCCTCCAAGAAGTTTGCCCGAATACCACCTGATCAACT
CAAGGCTATCGCTTTTAAATATCACCAACAAGGCAATATAAATGAGGCGCAAAAAGCCTATCAGGAATTTATTAATAGTG
GTTTAAGTGATCCAGATGTTTTCTCTAACTTTGCATTAATCTGTCAATCCCAAGGAGAGATTGACAAGGCAATAAAAGTC
TATAAGAAAAGCGTCAAACTATTTCCTGGCCATGCTTTTTCACATGCAAACTTGGGATATCTTCTCTTTCAGATAGGAAT
GTTAGATGATGCTGAAGTGGCTATCCGCCAGGCGATTGTTATACAGCCTAACCTCGCCAATGCTTATTCATACTTGGGTT
TAGTTTTACGAGAAAAAGGAAGACTAACTGATGCAGAAGATATAACCCGAAAGGCCATTGAACTTCAACCAGATTTGGCT
GATGCATACGTAAACCTTGGTCAGATCCTACAGAATCAAGGCAAACTAGATGAAGCAGAACATACAACACGCAAGGCAAT
TGAATTACAAGATGATTCGGCAAGTATATATCTCAATCTAGGTGGTATCCTGCAAGACCAAGGTAATCTAACTGATGCAG
AAGCGAACACAAGAAAGGCAATGAACTTACAGGCCGATCTGCCTGATGTCAATTTAAACCTTTCTATAATTTTAAAGGAT
CTTGGCAGATTAGAGGAGGCTGTATTTCATTTAACAAGAGAAATTGAGCTTTACCCACAAAACCAATCATCATATTTGCT
TCTTAACTCACTGCTTGAGGAATCTGATCTTTCATTCTTACCTGAAAGACAGTCTAGAATTTTGCTTCGTGGCCTATTAA
AGAGAAATGATATTGCACATAAAAATCTATTTTCAGCAATTAATCGCTTGATCTCAGAACAAACACTAGACAAAATTTCA
GGCATTCATCATGATTTATTTGATGACCCCTCTTTTCAACAAATTCTTGCTGATGATGAGATAATCAGTGCCCTTGGTTT
GATGTTATTTACCACAATGGCCTGGGAGAAGGCATTGACTAATATACGCAAGCAAATATGCCTTTCAATTCAAAATAATG
GTTTTGATAAAAGGATTATTGATTTAACTATTGCTCTTGCGGAGCAGTGTTTCCTAAATGAATATGTTTTTACATTTACC
AAGCAAGAATCTGATGCAATAGAACAGTTTAAACTTTCCTACTTGAGAAGTGATTTTGATTTAAAAACTCTTTCTATCTT
AGCTTGTTATATACCCATTACACATCTTTCTGAACAGTTCCCTTTATTAAGAGGATTCATCGATGAAAATGAGAAATTAA
ATAATTTAAAAATTATGCAACTCGTCGAACCCGAACGTGAACATGATTTTGCAGTATCTATTCCTAAATATGGATCTATA
GATGATGGTACTTCTATTCAGGTTAAAAAGCAGTATGAAGAGCATCCTTATCCGCGTTGGAGATATGCTTCTTATTCAAG
TGAAAATATTCAAACTATATCTTCAGCGATTAATAATGAAATAAACCCTAATCGGATCTCAATCATTTTGCCCAAGCAGA
GATCTCGCGTCTTAATAGCTGGCTGTGGAACCGGACAGCAAATATTCGATGCCCTCTCTTATTCTAACTCTGATTTAACT
GCTATCGATCTCAGTTCTTCTAGTATCGCTTATGCAAAGCGTAAGGCTCATGAATATGGAATTGAGCATATAAGATTTAT
AGAGATGGATATTCTTGATCTTCCAAAACTAAATGAAGAATTTGATCTCATAGAATGTACGGGAGTTCTCCATCATATGA
AGGACCCATCTGAAGGTCTGCAATCTCTACTTACAATACTCGCATCCGATGGAATGCTCAAATTAGGTTTTTATAGTGAG
CTAGCACGTCAAGATATTGTCGAGGCTAGGAAAATTATTAAATCAGAATCTTTTGAGGCTAGTAATGAAGGCATTTGTCT
ATTTAGGGATAAACTAATCAACGGTGAATATCCGAACATTAGTTCAATCTCAAACTGGCCAGACTTCTACACAACTTCTA
TGTGTAGAGACCTTTGTTTTCATATTATGGAGCATCGTTACTCACTAGTGATGATAGCATCGCTGCTTGAACAATTTGAA
CTTAGATTCTTAGGTTTTGTGTTGCCAAGTATTGTTAAAAAAGATTATGCCAGGGCTTATCCATCTGATGCAATGCAGAC
TGACCTCGGCTATTGGCACGAGTATGAACAAGCCAATCCCAATACCTTTCGACAAATGTACCAGTTCTGGACGAATAGAA
AGAAGATAATGTATTACGGTTAA

Upstream 100 bases:

>100_bases
TCTCTTGCCCATCAAAAAAGTCCATCGTTTCATGCTATTACCTTCAAGGTTCAAGAATTTCTTTGGCGATTAGATTAAAG
AAGAATATCTCGTTGTGAAC

Downstream 100 bases:

>100_bases
AATTTCTGCAAAAAGCATTGATAATTTTCGCGCTAAACAATATTGAACAATGTGGATGATTAAGTGTATTGCCTGGCAAC
CACTCTAATGCTATAATAAT

Product: SAM-binding motif-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 780; Mature: 780

Protein sequence:

>780_residues
MKGFGEKKKIKNKQPSKKFARIPPDQLKAIAFKYHQQGNINEAQKAYQEFINSGLSDPDVFSNFALICQSQGEIDKAIKV
YKKSVKLFPGHAFSHANLGYLLFQIGMLDDAEVAIRQAIVIQPNLANAYSYLGLVLREKGRLTDAEDITRKAIELQPDLA
DAYVNLGQILQNQGKLDEAEHTTRKAIELQDDSASIYLNLGGILQDQGNLTDAEANTRKAMNLQADLPDVNLNLSIILKD
LGRLEEAVFHLTREIELYPQNQSSYLLLNSLLEESDLSFLPERQSRILLRGLLKRNDIAHKNLFSAINRLISEQTLDKIS
GIHHDLFDDPSFQQILADDEIISALGLMLFTTMAWEKALTNIRKQICLSIQNNGFDKRIIDLTIALAEQCFLNEYVFTFT
KQESDAIEQFKLSYLRSDFDLKTLSILACYIPITHLSEQFPLLRGFIDENEKLNNLKIMQLVEPEREHDFAVSIPKYGSI
DDGTSIQVKKQYEEHPYPRWRYASYSSENIQTISSAINNEINPNRISIILPKQRSRVLIAGCGTGQQIFDALSYSNSDLT
AIDLSSSSIAYAKRKAHEYGIEHIRFIEMDILDLPKLNEEFDLIECTGVLHHMKDPSEGLQSLLTILASDGMLKLGFYSE
LARQDIVEARKIIKSESFEASNEGICLFRDKLINGEYPNISSISNWPDFYTTSMCRDLCFHIMEHRYSLVMIASLLEQFE
LRFLGFVLPSIVKKDYARAYPSDAMQTDLGYWHEYEQANPNTFRQMYQFWTNRKKIMYYG

Sequences:

>Translated_780_residues
MKGFGEKKKIKNKQPSKKFARIPPDQLKAIAFKYHQQGNINEAQKAYQEFINSGLSDPDVFSNFALICQSQGEIDKAIKV
YKKSVKLFPGHAFSHANLGYLLFQIGMLDDAEVAIRQAIVIQPNLANAYSYLGLVLREKGRLTDAEDITRKAIELQPDLA
DAYVNLGQILQNQGKLDEAEHTTRKAIELQDDSASIYLNLGGILQDQGNLTDAEANTRKAMNLQADLPDVNLNLSIILKD
LGRLEEAVFHLTREIELYPQNQSSYLLLNSLLEESDLSFLPERQSRILLRGLLKRNDIAHKNLFSAINRLISEQTLDKIS
GIHHDLFDDPSFQQILADDEIISALGLMLFTTMAWEKALTNIRKQICLSIQNNGFDKRIIDLTIALAEQCFLNEYVFTFT
KQESDAIEQFKLSYLRSDFDLKTLSILACYIPITHLSEQFPLLRGFIDENEKLNNLKIMQLVEPEREHDFAVSIPKYGSI
DDGTSIQVKKQYEEHPYPRWRYASYSSENIQTISSAINNEINPNRISIILPKQRSRVLIAGCGTGQQIFDALSYSNSDLT
AIDLSSSSIAYAKRKAHEYGIEHIRFIEMDILDLPKLNEEFDLIECTGVLHHMKDPSEGLQSLLTILASDGMLKLGFYSE
LARQDIVEARKIIKSESFEASNEGICLFRDKLINGEYPNISSISNWPDFYTTSMCRDLCFHIMEHRYSLVMIASLLEQFE
LRFLGFVLPSIVKKDYARAYPSDAMQTDLGYWHEYEQANPNTFRQMYQFWTNRKKIMYYG
>Mature_780_residues
MKGFGEKKKIKNKQPSKKFARIPPDQLKAIAFKYHQQGNINEAQKAYQEFINSGLSDPDVFSNFALICQSQGEIDKAIKV
YKKSVKLFPGHAFSHANLGYLLFQIGMLDDAEVAIRQAIVIQPNLANAYSYLGLVLREKGRLTDAEDITRKAIELQPDLA
DAYVNLGQILQNQGKLDEAEHTTRKAIELQDDSASIYLNLGGILQDQGNLTDAEANTRKAMNLQADLPDVNLNLSIILKD
LGRLEEAVFHLTREIELYPQNQSSYLLLNSLLEESDLSFLPERQSRILLRGLLKRNDIAHKNLFSAINRLISEQTLDKIS
GIHHDLFDDPSFQQILADDEIISALGLMLFTTMAWEKALTNIRKQICLSIQNNGFDKRIIDLTIALAEQCFLNEYVFTFT
KQESDAIEQFKLSYLRSDFDLKTLSILACYIPITHLSEQFPLLRGFIDENEKLNNLKIMQLVEPEREHDFAVSIPKYGSI
DDGTSIQVKKQYEEHPYPRWRYASYSSENIQTISSAINNEINPNRISIILPKQRSRVLIAGCGTGQQIFDALSYSNSDLT
AIDLSSSSIAYAKRKAHEYGIEHIRFIEMDILDLPKLNEEFDLIECTGVLHHMKDPSEGLQSLLTILASDGMLKLGFYSE
LARQDIVEARKIIKSESFEASNEGICLFRDKLINGEYPNISSISNWPDFYTTSMCRDLCFHIMEHRYSLVMIASLLEQFE
LRFLGFVLPSIVKKDYARAYPSDAMQTDLGYWHEYEQANPNTFRQMYQFWTNRKKIMYYG

Specific function: Unknown

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv2067c [H]

Homologues:

Organism=Homo sapiens, GI32307148, Length=237, Percent_Identity=32.4894514767932, Blast_Score=120, Evalue=6e-27,
Organism=Homo sapiens, GI32307150, Length=237, Percent_Identity=32.4894514767932, Blast_Score=120, Evalue=6e-27,
Organism=Homo sapiens, GI118766330, Length=205, Percent_Identity=28.2926829268293, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI118766328, Length=205, Percent_Identity=28.2926829268293, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI22749211, Length=153, Percent_Identity=32.6797385620915, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI83415184, Length=206, Percent_Identity=27.6699029126214, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI301336134, Length=206, Percent_Identity=27.6699029126214, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115532692, Length=226, Percent_Identity=30.5309734513274, Blast_Score=115, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI115532690, Length=226, Percent_Identity=30.5309734513274, Blast_Score=115, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI25147174, Length=180, Percent_Identity=27.2222222222222, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17647755, Length=242, Percent_Identity=32.6446280991736, Blast_Score=118, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24585827, Length=242, Percent_Identity=32.6446280991736, Blast_Score=118, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24585829, Length=242, Percent_Identity=32.6446280991736, Blast_Score=118, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24656717, Length=218, Percent_Identity=28.8990825688073, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI18110006, Length=218, Percent_Identity=28.8990825688073, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI19920486, Length=255, Percent_Identity=25.8823529411765, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI161076610, Length=255, Percent_Identity=25.8823529411765, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24647123, Length=170, Percent_Identity=28.2352941176471, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281364285, Length=259, Percent_Identity=26.2548262548263, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24581187, Length=259, Percent_Identity=26.2548262548263, Blast_Score=74, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 89167; Mature: 89167

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGFGEKKKIKNKQPSKKFARIPPDQLKAIAFKYHQQGNINEAQKAYQEFINSGLSDPDV
CCCCCCHHHHCCCCCCHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHH
FSNFALICQSQGEIDKAIKVYKKSVKLFPGHAFSHANLGYLLFQIGMLDDAEVAIRQAIV
HHHHHHEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHEE
IQPNLANAYSYLGLVLREKGRLTDAEDITRKAIELQPDLADAYVNLGQILQNQGKLDEAE
ECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHH
HTTRKAIELQDDSASIYLNLGGILQDQGNLTDAEANTRKAMNLQADLPDVNLNLSIILKD
HHHHHHEEEECCCCEEEEEECCEEECCCCCCCCCCCCHHHCEEECCCCCCCCHHHHHHHH
LGRLEEAVFHLTREIELYPQNQSSYLLLNSLLEESDLSFLPERQSRILLRGLLKRNDIAH
HHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHH
KNLFSAINRLISEQTLDKISGIHHDLFDDPSFQQILADDEIISALGLMLFTTMAWEKALT
HHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIRKQICLSIQNNGFDKRIIDLTIALAEQCFLNEYVFTFTKQESDAIEQFKLSYLRSDFD
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHCCCC
LKTLSILACYIPITHLSEQFPLLRGFIDENEKLNNLKIMQLVEPEREHDFAVSIPKYGSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCC
DDGTSIQVKKQYEEHPYPRWRYASYSSENIQTISSAINNEINPNRISIILPKQRSRVLIA
CCCCCEEEEEHHHCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEE
GCGTGQQIFDALSYSNSDLTAIDLSSSSIAYAKRKAHEYGIEHIRFIEMDILDLPKLNEE
ECCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCHHEEEEEEHHHCCCCCCCC
FDLIECTGVLHHMKDPSEGLQSLLTILASDGMLKLGFYSELARQDIVEARKIIKSESFEA
CCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCC
SNEGICLFRDKLINGEYPNISSISNWPDFYTTSMCRDLCFHIMEHRYSLVMIASLLEQFE
CCCCEEEEEEHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRFLGFVLPSIVKKDYARAYPSDAMQTDLGYWHEYEQANPNTFRQMYQFWTNRKKIMYYG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MKGFGEKKKIKNKQPSKKFARIPPDQLKAIAFKYHQQGNINEAQKAYQEFINSGLSDPDV
CCCCCCHHHHCCCCCCHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHH
FSNFALICQSQGEIDKAIKVYKKSVKLFPGHAFSHANLGYLLFQIGMLDDAEVAIRQAIV
HHHHHHEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHEE
IQPNLANAYSYLGLVLREKGRLTDAEDITRKAIELQPDLADAYVNLGQILQNQGKLDEAE
ECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHH
HTTRKAIELQDDSASIYLNLGGILQDQGNLTDAEANTRKAMNLQADLPDVNLNLSIILKD
HHHHHHEEEECCCCEEEEEECCEEECCCCCCCCCCCCHHHCEEECCCCCCCCHHHHHHHH
LGRLEEAVFHLTREIELYPQNQSSYLLLNSLLEESDLSFLPERQSRILLRGLLKRNDIAH
HHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHH
KNLFSAINRLISEQTLDKISGIHHDLFDDPSFQQILADDEIISALGLMLFTTMAWEKALT
HHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIRKQICLSIQNNGFDKRIIDLTIALAEQCFLNEYVFTFTKQESDAIEQFKLSYLRSDFD
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHCCCC
LKTLSILACYIPITHLSEQFPLLRGFIDENEKLNNLKIMQLVEPEREHDFAVSIPKYGSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCC
DDGTSIQVKKQYEEHPYPRWRYASYSSENIQTISSAINNEINPNRISIILPKQRSRVLIA
CCCCCEEEEEHHHCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEE
GCGTGQQIFDALSYSNSDLTAIDLSSSSIAYAKRKAHEYGIEHIRFIEMDILDLPKLNEE
ECCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCHHEEEEEEHHHCCCCCCCC
FDLIECTGVLHHMKDPSEGLQSLLTILASDGMLKLGFYSELARQDIVEARKIIKSESFEA
CCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCC
SNEGICLFRDKLINGEYPNISSISNWPDFYTTSMCRDLCFHIMEHRYSLVMIASLLEQFE
CCCCEEEEEEHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRFLGFVLPSIVKKDYARAYPSDAMQTDLGYWHEYEQANPNTFRQMYQFWTNRKKIMYYG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3041005; 1901865 [H]