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The map label for this gene is folB [H]

Identifier: 124023546

GI number: 124023546

Start: 1608357

End: 1608740

Strand: Direct

Name: folB [H]

Synonym: P9303_18461

Alternate gene names: 124023546

Gene position: 1608357-1608740 (Clockwise)

Preceding gene: 124023545

Following gene: 124023547

Centisome position: 59.95

GC content: 52.6

Gene sequence:

>384_bases
GTGATCAATCGCCTCCCTTTAGGAGCCATTCATGTTAACGATGTGCGCTTGTGGGCTCACGTGGGTGTGCTTGACCATGA
AAGACGTGAAGGTCAGTGGTTCAGCTTGGATTTCAGCCTTTGGTTAGACCTTGACAAGGCTGCCCTGGATGATGACCTCA
ATGCCACTGCGGACTACAGCTTGGCTATTGGTGCAATGCAACGACTCTCCTTTGAACTGAAGTGTTTCACCATCGAACAC
TTCAGCGAGCAATTGCTAGTGCTCTTGGAAGATCTCTACGGTCCTGTGCCGATGCGAGTGCTTGTGCGTAAATGTGCTGC
GCCGGTGCCTGGGTTTAGTGGCAGTGTGGCTGTTGAGAGGTGTCGCCATTGGCCAACACCCTGA

Upstream 100 bases:

>100_bases
AAGGGCTGGTGACCTATCGCTATCGGTTGCGTGGACAAGGCCAGATTGTGGCGGACTATGCCAATGGTGAATGCATGTTC
ACGCACCGGGACCTACCGCT

Downstream 100 bases:

>100_bases
TCTTTGTTAAGGCTTTTCGCGATGTTTACGCATGTCGCATCAGTGGATAAACCCCGTCGACCATTGGTGCTTGTACATGG
TCTTTGGGATACCCCGCATC

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MINRLPLGAIHVNDVRLWAHVGVLDHERREGQWFSLDFSLWLDLDKAALDDDLNATADYSLAIGAMQRLSFELKCFTIEH
FSEQLLVLLEDLYGPVPMRVLVRKCAAPVPGFSGSVAVERCRHWPTP

Sequences:

>Translated_127_residues
MINRLPLGAIHVNDVRLWAHVGVLDHERREGQWFSLDFSLWLDLDKAALDDDLNATADYSLAIGAMQRLSFELKCFTIEH
FSEQLLVLLEDLYGPVPMRVLVRKCAAPVPGFSGSVAVERCRHWPTP
>Mature_127_residues
MINRLPLGAIHVNDVRLWAHVGVLDHERREGQWFSLDFSLWLDLDKAALDDDLNATADYSLAIGAMQRLSFELKCFTIEH
FSEQLLVLLEDLYGPVPMRVLVRKCAAPVPGFSGSVAVERCRHWPTP

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 14400; Mature: 14400

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINRLPLGAIHVNDVRLWAHVGVLDHERREGQWFSLDFSLWLDLDKAALDDDLNATADYS
CCCCCCCCEEEECCEEEEEEECCCCCCCCCCCEEEEEEEEEEECCHHHCCCCCCCCCCHH
LAIGAMQRLSFELKCFTIEHFSEQLLVLLEDLYGPVPMRVLVRKCAAPVPGFSGSVAVER
HHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHH
CRHWPTP
HHCCCCC
>Mature Secondary Structure
MINRLPLGAIHVNDVRLWAHVGVLDHERREGQWFSLDFSLWLDLDKAALDDDLNATADYS
CCCCCCCCEEEECCEEEEEEECCCCCCCCCCCEEEEEEEEEEECCHHHCCCCCCCCCCHH
LAIGAMQRLSFELKCFTIEHFSEQLLVLLEDLYGPVPMRVLVRKCAAPVPGFSGSVAVER
HHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHH
CRHWPTP
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]