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The map label for this gene is ybbO [C]

Identifier: 124023496

GI number: 124023496

Start: 1567116

End: 1568018

Strand: Direct

Name: ybbO [C]

Synonym: P9303_17961

Alternate gene names: 124023496

Gene position: 1567116-1568018 (Clockwise)

Preceding gene: 124023495

Following gene: 124023497

Centisome position: 58.42

GC content: 49.39

Gene sequence:

>903_bases
ATGAGTTGGAAAGTTGCAGATATCCCTGATCAGAAAGGAAGGGTTGCATTAGTAACAGGTGCCAATAGTGGCCTTGGTCT
TGAGACGGCCAAGGCATTGCTTAACAAGGGCGCCAGAGTCATTATGGCTTGTCGCTCACGACCCAAAGGTGAAGCTGTAC
GCCAAATTATTCTCGAGAGCAATGATTCCACAAAGCTTGATCTGATTGAGTTAGATCTCGCTGATTTAGCGAGCGTTAGA
CGTGCAGCTGAGCAGGTAGAAAGACAATACAGCCGAGTGGACCTGCTAATTAATAATGCTGGAGTAATGGCTACTCCACA
GACCCTCAGCAAACAGGGTCTGGAGCTTCAGTTCGCCGTTAATCATCTTGGCCACATGGCATTGACCCTAAAGCTCCTAC
CCTTACTCGCAAAGCAACATGGAGCAAGGGTTGTTACCGTCACTTCTGGCGCACAGTACATGGGTCGAATCGCATGGGAG
GATCTTCAAGGGATCAAGCACTATGACCGCTGGGCTGCCTACTCACAAAGCAAACTTGCTAATGTGATGTTCGCCTTAGA
GCTCGACAAGCGAGTGCGCAATGCAGCAAGTGGGATTGCATCATTGTTGGCACATCCAGGTCTTGCACGCACTAATTTGC
AGCCTAAATCTGTTGCTGCGAACAAATCCTGGCAGGAAGGCCTTGCTTATCGGTTAATGGATCCCATGTTTCAGAGCGCT
GCAATGGGATCCCTACCGCAATTACATGCTGCAACCGCGCCAACTGCTCAAGGCGGCGAACAATACGGACCTAGATTTAA
CTTTAGGGGTTACCCCAAGCTTTGCCGCATTGCCCCGTTGGCACTTAGGGAGGAAGACCGTCAAAGGCTTTGGAGCATCA
GTGAAAAACTTTTAGAGATTTGA

Upstream 100 bases:

>100_bases
GTAACCATTAAGGAATTACAGGCCCTGCTCAAGATGCTATGCAGCAGCTTATGCTTCAATGTTCTACTTTATGGATCACC
GCTGATAAGGGAGCCACCTG

Downstream 100 bases:

>100_bases
ACTTGCCATTAACAAGTATTTTAACGCTTTCCTTGGTTTAATCTGTCACTTTTGACTCTCACAGCTATGATCTAATGGCA
GTGAATTCCGCCCATGCCTG

Product: Short-chain dehydrogenase/reductase (SDR) superfamily protein

Products: protochlorophyllide; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSWKVADIPDQKGRVALVTGANSGLGLETAKALLNKGARVIMACRSRPKGEAVRQIILESNDSTKLDLIELDLADLASVR
RAAEQVERQYSRVDLLINNAGVMATPQTLSKQGLELQFAVNHLGHMALTLKLLPLLAKQHGARVVTVTSGAQYMGRIAWE
DLQGIKHYDRWAAYSQSKLANVMFALELDKRVRNAASGIASLLAHPGLARTNLQPKSVAANKSWQEGLAYRLMDPMFQSA
AMGSLPQLHAATAPTAQGGEQYGPRFNFRGYPKLCRIAPLALREEDRQRLWSISEKLLEI

Sequences:

>Translated_300_residues
MSWKVADIPDQKGRVALVTGANSGLGLETAKALLNKGARVIMACRSRPKGEAVRQIILESNDSTKLDLIELDLADLASVR
RAAEQVERQYSRVDLLINNAGVMATPQTLSKQGLELQFAVNHLGHMALTLKLLPLLAKQHGARVVTVTSGAQYMGRIAWE
DLQGIKHYDRWAAYSQSKLANVMFALELDKRVRNAASGIASLLAHPGLARTNLQPKSVAANKSWQEGLAYRLMDPMFQSA
AMGSLPQLHAATAPTAQGGEQYGPRFNFRGYPKLCRIAPLALREEDRQRLWSISEKLLEI
>Mature_299_residues
SWKVADIPDQKGRVALVTGANSGLGLETAKALLNKGARVIMACRSRPKGEAVRQIILESNDSTKLDLIELDLADLASVRR
AAEQVERQYSRVDLLINNAGVMATPQTLSKQGLELQFAVNHLGHMALTLKLLPLLAKQHGARVVTVTSGAQYMGRIAWED
LQGIKHYDRWAAYSQSKLANVMFALELDKRVRNAASGIASLLAHPGLARTNLQPKSVAANKSWQEGLAYRLMDPMFQSAA
MGSLPQLHAATAPTAQGGEQYGPRFNFRGYPKLCRIAPLALREEDRQRLWSISEKLLEI

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI186928839, Length=291, Percent_Identity=38.1443298969072, Blast_Score=171, Evalue=7e-43,
Organism=Homo sapiens, GI166795268, Length=291, Percent_Identity=35.3951890034364, Blast_Score=154, Evalue=6e-38,
Organism=Homo sapiens, GI7706523, Length=303, Percent_Identity=34.983498349835, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI10190746, Length=309, Percent_Identity=35.5987055016181, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI225579078, Length=299, Percent_Identity=36.4548494983278, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI193804850, Length=296, Percent_Identity=32.7702702702703, Blast_Score=134, Evalue=8e-32,
Organism=Homo sapiens, GI146231950, Length=204, Percent_Identity=39.7058823529412, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI19923931, Length=230, Percent_Identity=36.5217391304348, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI7705421, Length=233, Percent_Identity=28.3261802575107, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI13375997, Length=159, Percent_Identity=33.9622641509434, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI72534732, Length=159, Percent_Identity=33.9622641509434, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI20149619, Length=233, Percent_Identity=29.6137339055794, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI40548397, Length=215, Percent_Identity=32.5581395348837, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI214010158, Length=215, Percent_Identity=32.5581395348837, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI214010156, Length=215, Percent_Identity=32.5581395348837, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI22758144, Length=215, Percent_Identity=32.5581395348837, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI7706318, Length=228, Percent_Identity=28.0701754385965, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI150247226, Length=210, Percent_Identity=30.4761904761905, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1786701, Length=203, Percent_Identity=30.5418719211823, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786812, Length=207, Percent_Identity=28.5024154589372, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17558006, Length=211, Percent_Identity=38.8625592417062, Blast_Score=131, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17532791, Length=302, Percent_Identity=28.476821192053, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17532805, Length=307, Percent_Identity=31.2703583061889, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI193207620, Length=299, Percent_Identity=30.1003344481605, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17505416, Length=215, Percent_Identity=33.4883720930233, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI72001364, Length=214, Percent_Identity=33.6448598130841, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71992402, Length=258, Percent_Identity=28.2945736434109, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32565532, Length=211, Percent_Identity=30.3317535545024, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17535059, Length=258, Percent_Identity=26.7441860465116, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI115533174, Length=181, Percent_Identity=33.1491712707182, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI115533172, Length=181, Percent_Identity=33.1491712707182, Blast_Score=81, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6324820, Length=295, Percent_Identity=28.135593220339, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6322227, Length=210, Percent_Identity=25.2380952380952, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45554248, Length=293, Percent_Identity=39.2491467576792, Blast_Score=168, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24640117, Length=293, Percent_Identity=39.2491467576792, Blast_Score=168, Evalue=4e-42,
Organism=Drosophila melanogaster, GI28573296, Length=290, Percent_Identity=36.8965517241379, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI22024069, Length=291, Percent_Identity=36.0824742268041, Blast_Score=160, Evalue=9e-40,
Organism=Drosophila melanogaster, GI19921754, Length=245, Percent_Identity=39.1836734693878, Blast_Score=157, Evalue=8e-39,
Organism=Drosophila melanogaster, GI24586328, Length=287, Percent_Identity=35.8885017421603, Blast_Score=154, Evalue=5e-38,
Organism=Drosophila melanogaster, GI161076371, Length=245, Percent_Identity=36.734693877551, Blast_Score=153, Evalue=1e-37,
Organism=Drosophila melanogaster, GI20129347, Length=298, Percent_Identity=33.2214765100671, Blast_Score=144, Evalue=9e-35,
Organism=Drosophila melanogaster, GI24656154, Length=254, Percent_Identity=37.007874015748, Blast_Score=138, Evalue=5e-33,
Organism=Drosophila melanogaster, GI19922628, Length=254, Percent_Identity=37.007874015748, Blast_Score=138, Evalue=5e-33,
Organism=Drosophila melanogaster, GI45553409, Length=301, Percent_Identity=31.5614617940199, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24647948, Length=301, Percent_Identity=31.5614617940199, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24647946, Length=301, Percent_Identity=31.5614617940199, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24647931, Length=314, Percent_Identity=28.0254777070064, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21358495, Length=205, Percent_Identity=32.6829268292683, Blast_Score=85, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.3.1.33

Molecular weight: Translated: 32961; Mature: 32829

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWKVADIPDQKGRVALVTGANSGLGLETAKALLNKGARVIMACRSRPKGEAVRQIILES
CCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEHHHCCCCCHHHHHHHHHCC
NDSTKLDLIELDLADLASVRRAAEQVERQYSRVDLLINNAGVMATPQTLSKQGLELQFAV
CCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEECCHHHHHCCCEEEEHH
NHLGHMALTLKLLPLLAKQHGARVVTVTSGAQYMGRIAWEDLQGIKHYDRWAAYSQSKLA
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVMFALELDKRVRNAASGIASLLAHPGLARTNLQPKSVAANKSWQEGLAYRLMDPMFQSA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHH
AMGSLPQLHAATAPTAQGGEQYGPRFNFRGYPKLCRIAPLALREEDRQRLWSISEKLLEI
HHCCCCHHHHCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SWKVADIPDQKGRVALVTGANSGLGLETAKALLNKGARVIMACRSRPKGEAVRQIILES
CCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEHHHCCCCCHHHHHHHHHCC
NDSTKLDLIELDLADLASVRRAAEQVERQYSRVDLLINNAGVMATPQTLSKQGLELQFAV
CCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEECCHHHHHCCCEEEEHH
NHLGHMALTLKLLPLLAKQHGARVVTVTSGAQYMGRIAWEDLQGIKHYDRWAAYSQSKLA
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVMFALELDKRVRNAASGIASLLAHPGLARTNLQPKSVAANKSWQEGLAYRLMDPMFQSA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHH
AMGSLPQLHAATAPTAQGGEQYGPRFNFRGYPKLCRIAPLALREEDRQRLWSISEKLLEI
HHCCCCHHHHCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: chlorophyllide a; NADP+

Specific reaction: chlorophyllide a + NADP+ = protochlorophyllide + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]