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The map label for this gene is 124023463

Identifier: 124023463

GI number: 124023463

Start: 1539697

End: 1540278

Strand: Direct

Name: 124023463

Synonym: P9303_17631

Alternate gene names: NA

Gene position: 1539697-1540278 (Clockwise)

Preceding gene: 124023462

Following gene: 124023466

Centisome position: 57.39

GC content: 46.56

Gene sequence:

>582_bases
GTGAACCAAACCAAACGTAAACAGATACTGACATTTCGGTTATTGCTCCCTCTCATCATTGTGGGGATTGCTTGGCTGCA
GGAAAGTATTGATCAGCTATTTTTTTCGGGGAGTTGGAATCTGCCATTAGGGCCTGGTCTGCCTTGGTGGGGTCTACTTA
CAGCTCCATTTAGCCATGCAGGTTTTGGCCATCTGATCTCTAACACAATTATGTTTTTGCCTTTGAGCTGGTTGGTGCTA
ACCAAGGGCTTTCGTGATTACATTGCTGTTTTGATCGCTGTTGTTGTGATGGAAATACCTGTTTGGTTGTTTTGGCCTAG
AGGTAGCCATGGCATGTCGGGCGTCTTGTATGGACTGCTCGGATACCTGTTGCTGATTGGTTTCCTTGAACGCCGTTTCA
TGACCATTTTATTGTCAATCGTGGGTTTGGTTCTTTTTGGAAATGCACTTCCAGCTTTGATCCCAGGCGTGTCTCCGGCT
GGAGTGAGCTGGATCGGACATGCTAGTGGATTTCTTGGAGGTATTTTTGCTGCACTTGCTCTTTCACGGGAGCCAAAGGG
ATTGAATAAGGCTAAGGGTTGA

Upstream 100 bases:

>100_bases
TGCACCTCTGCTGATTACTGCGATGTCTTAATGGAGTTGTAGGGGAGTTGCAGCACAATAAAATGGTGAATCATGCAATT
GTCATTTCAAAGCATCTTGA

Downstream 100 bases:

>100_bases
CAATAAAATATTTTTCTAGCTATATATGTTCATATAATTCTTGACGTCATTTGCGCATGCATAATTATAGATGATATCTG
ATTATTTATCGAGCTAGGCT

Product: rhomboid family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MNQTKRKQILTFRLLLPLIIVGIAWLQESIDQLFFSGSWNLPLGPGLPWWGLLTAPFSHAGFGHLISNTIMFLPLSWLVL
TKGFRDYIAVLIAVVVMEIPVWLFWPRGSHGMSGVLYGLLGYLLLIGFLERRFMTILLSIVGLVLFGNALPALIPGVSPA
GVSWIGHASGFLGGIFAALALSREPKGLNKAKG

Sequences:

>Translated_193_residues
MNQTKRKQILTFRLLLPLIIVGIAWLQESIDQLFFSGSWNLPLGPGLPWWGLLTAPFSHAGFGHLISNTIMFLPLSWLVL
TKGFRDYIAVLIAVVVMEIPVWLFWPRGSHGMSGVLYGLLGYLLLIGFLERRFMTILLSIVGLVLFGNALPALIPGVSPA
GVSWIGHASGFLGGIFAALALSREPKGLNKAKG
>Mature_193_residues
MNQTKRKQILTFRLLLPLIIVGIAWLQESIDQLFFSGSWNLPLGPGLPWWGLLTAPFSHAGFGHLISNTIMFLPLSWLVL
TKGFRDYIAVLIAVVVMEIPVWLFWPRGSHGMSGVLYGLLGYLLLIGFLERRFMTILLSIVGLVLFGNALPALIPGVSPA
GVSWIGHASGFLGGIFAALALSREPKGLNKAKG

Specific function: Unknown

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML1171 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022764 [H]

Pfam domain/function: PF01694 Rhomboid [H]

EC number: NA

Molecular weight: Translated: 21079; Mature: 21079

Theoretical pI: Translated: 10.88; Mature: 10.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQTKRKQILTFRLLLPLIIVGIAWLQESIDQLFFSGSWNLPLGPGLPWWGLLTAPFSHA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCC
GFGHLISNTIMFLPLSWLVLTKGFRDYIAVLIAVVVMEIPVWLFWPRGSHGMSGVLYGLL
CHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHEECCCCCCCHHHHHHHHH
GYLLLIGFLERRFMTILLSIVGLVLFGNALPALIPGVSPAGVSWIGHASGFLGGIFAALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LSREPKGLNKAKG
HCCCCCCCCCCCC
>Mature Secondary Structure
MNQTKRKQILTFRLLLPLIIVGIAWLQESIDQLFFSGSWNLPLGPGLPWWGLLTAPFSHA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCC
GFGHLISNTIMFLPLSWLVLTKGFRDYIAVLIAVVVMEIPVWLFWPRGSHGMSGVLYGLL
CHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHEECCCCCCCHHHHHHHHH
GYLLLIGFLERRFMTILLSIVGLVLFGNALPALIPGVSPAGVSWIGHASGFLGGIFAALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LSREPKGLNKAKG
HCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]