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The map label for this gene is glnH [C]

Identifier: 124023452

GI number: 124023452

Start: 1532370

End: 1533371

Strand: Direct

Name: glnH [C]

Synonym: P9303_17521

Alternate gene names: 124023452

Gene position: 1532370-1533371 (Clockwise)

Preceding gene: 124023450

Following gene: 124023455

Centisome position: 57.12

GC content: 43.21

Gene sequence:

>1002_bases
ATGGCTTTAAGGGTTGGAGTGAGTGGTTCGCCACCATTTGTGGACAAGAGGGCTGATGTATATGAGGGGATTAGTATTGA
AGTTTGGGAACAAATCGCTAATGCAGAGAAGCTTGAATACATTCTCGTTCCATATCCCAACATAGATTCGAACATCAAGG
CGGTTGCTGATGGAAAGATTGATTTAGCCATCGGGCCTATCAGCATTACGCCAGATCGGGCGGCAAAAAATGGGATTGAA
TTCACTCAACCTTATTTCTATGCAGAGGAGGGTGTTTTAGTACCATCACAGCCACCCGGATTGTGGACGAGGATCAAACC
TCTCTTTGGTGTCGCTGCTTTATCTTCTATCACGTTCTTGCTATTTACACTTTTTTGTGTAGGCAATCTGATTTGGCTTG
CAGAGCGAAAACGCAACCCTGAACATTTTCCTCCTCAATATATAAAGGGTCTAGGGAATGGGATTTGGTTTGCCTTGGTT
ACACTCACCACCGTAGGTTACGGAGACCGTGCACCTTTAACGAAAGCAGGAAGGACTATAGCAGGGGTCTGGATGGTAAT
TTCGCTAGTATCAGTGTCGACAATTACTGCAGGATTGGCTTCGGCATTTACCGTCTCGCTATCTCAGACACAATTGTCTA
GGATCATGAAACCATCGGATTTGGATGGTGAACTAATTGGCGTAGTCACTGGCACCACAGGTGTATCTTTAGCAAGATCA
TATGGCGCACGGCCGTTGCCAGTACCAACCCTTAAGGAAGCTATTCATCTAATCAAGAAAAATAAAGTCTCAGGACTGAT
CTCAGACAAACCTATCTTGAGTTATTATATGAAAAATAATCCTGATAAATCTCTAAAATTAGCACCTTTTAGGCTTTCCC
TTCAGACCTATGGATTTGTCGTGCCTAGTGATAGTCCATTGGAACGTTTAATTAATATTGAACTCCTTCGTCTTGAACGC
AGTAATCAGGTTCAAGCGATAAGCGACAGGCTTTTGAAATAA

Upstream 100 bases:

>100_bases
TCATTTCGTGTATAGGCGATTGATGGGCGGCATGAATTTAAAGAGAAGGCTCTCCGTTGCTGCCTTGATTGTCATGGCGA
CTCCGTCTCCCCTTCAGGCA

Downstream 100 bases:

>100_bases
TTCCTCTGATCTAATGCTCACAAACATTTAGTTTTGCAGCTGACACTTCAGCACTGCTAGCGCTTCATCGGGTAGTCCCA
AAAATTGATCCAGCCATGCG

Product: GIC family ligand gated channel

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: Ionotropic Glutamate Receptor; Ligand-Gated Ion Channel Family Protein; Ion Transport 2 Domain-Containing Protein; Ion Channel Family; Glutamate-Gated Potassium Channel; Ligand Gated Channel; Ligand-Gated Ion Channel Periplasmic Domain

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MALRVGVSGSPPFVDKRADVYEGISIEVWEQIANAEKLEYILVPYPNIDSNIKAVADGKIDLAIGPISITPDRAAKNGIE
FTQPYFYAEEGVLVPSQPPGLWTRIKPLFGVAALSSITFLLFTLFCVGNLIWLAERKRNPEHFPPQYIKGLGNGIWFALV
TLTTVGYGDRAPLTKAGRTIAGVWMVISLVSVSTITAGLASAFTVSLSQTQLSRIMKPSDLDGELIGVVTGTTGVSLARS
YGARPLPVPTLKEAIHLIKKNKVSGLISDKPILSYYMKNNPDKSLKLAPFRLSLQTYGFVVPSDSPLERLINIELLRLER
SNQVQAISDRLLK

Sequences:

>Translated_333_residues
MALRVGVSGSPPFVDKRADVYEGISIEVWEQIANAEKLEYILVPYPNIDSNIKAVADGKIDLAIGPISITPDRAAKNGIE
FTQPYFYAEEGVLVPSQPPGLWTRIKPLFGVAALSSITFLLFTLFCVGNLIWLAERKRNPEHFPPQYIKGLGNGIWFALV
TLTTVGYGDRAPLTKAGRTIAGVWMVISLVSVSTITAGLASAFTVSLSQTQLSRIMKPSDLDGELIGVVTGTTGVSLARS
YGARPLPVPTLKEAIHLIKKNKVSGLISDKPILSYYMKNNPDKSLKLAPFRLSLQTYGFVVPSDSPLERLINIELLRLER
SNQVQAISDRLLK
>Mature_332_residues
ALRVGVSGSPPFVDKRADVYEGISIEVWEQIANAEKLEYILVPYPNIDSNIKAVADGKIDLAIGPISITPDRAAKNGIEF
TQPYFYAEEGVLVPSQPPGLWTRIKPLFGVAALSSITFLLFTLFCVGNLIWLAERKRNPEHFPPQYIKGLGNGIWFALVT
LTTVGYGDRAPLTKAGRTIAGVWMVISLVSVSTITAGLASAFTVSLSQTQLSRIMKPSDLDGELIGVVTGTTGVSLARSY
GARPLPVPTLKEAIHLIKKNKVSGLISDKPILSYYMKNNPDKSLKLAPFRLSLQTYGFVVPSDSPLERLINIELLRLERS
NQVQAISDRLLK

Specific function: Involved In A Glutamine-Transport System Glnhpq. [C]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI164419736, Length=356, Percent_Identity=24.7191011235955, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI164419734, Length=355, Percent_Identity=23.943661971831, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24644257, Length=289, Percent_Identity=22.1453287197232, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: 1440 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 460 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 36381; Mature: 36250

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALRVGVSGSPPFVDKRADVYEGISIEVWEQIANAEKLEYILVPYPNIDSNIKAVADGKI
CEEEECCCCCCCCCCCCCHHHCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEECCEE
DLAIGPISITPDRAAKNGIEFTQPYFYAEEGVLVPSQPPGLWTRIKPLFGVAALSSITFL
EEEEECEEECCCHHHHCCCCCCCCEEECCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHH
LFTLFCVGNLIWLAERKRNPEHFPPQYIKGLGNGIWFALVTLTTVGYGDRAPLTKAGRTI
HHHHHHHHHHEEEHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHCCCHH
AGVWMVISLVSVSTITAGLASAFTVSLSQTQLSRIMKPSDLDGELIGVVTGTTGVSLARS
HHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHH
YGARPLPVPTLKEAIHLIKKNKVSGLISDKPILSYYMKNNPDKSLKLAPFRLSLQTYGFV
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEEEEEEEEEHEEEE
VPSDSPLERLINIELLRLERSNQVQAISDRLLK
ECCCCHHHHHHCEEEEEECCCCCHHHHHHHHCC
>Mature Secondary Structure 
ALRVGVSGSPPFVDKRADVYEGISIEVWEQIANAEKLEYILVPYPNIDSNIKAVADGKI
EEEECCCCCCCCCCCCCHHHCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEECCEE
DLAIGPISITPDRAAKNGIEFTQPYFYAEEGVLVPSQPPGLWTRIKPLFGVAALSSITFL
EEEEECEEECCCHHHHCCCCCCCCEEECCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHH
LFTLFCVGNLIWLAERKRNPEHFPPQYIKGLGNGIWFALVTLTTVGYGDRAPLTKAGRTI
HHHHHHHHHHEEEHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHCCCHH
AGVWMVISLVSVSTITAGLASAFTVSLSQTQLSRIMKPSDLDGELIGVVTGTTGVSLARS
HHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHH
YGARPLPVPTLKEAIHLIKKNKVSGLISDKPILSYYMKNNPDKSLKLAPFRLSLQTYGFV
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEEEEEEEEEHEEEE
VPSDSPLERLINIELLRLERSNQVQAISDRLLK
ECCCCHHHHHHCEEEEEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: Translocates substrate across the membrane [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA