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The map label for this gene is purQ [H]

Identifier: 124023427

GI number: 124023427

Start: 1509314

End: 1509967

Strand: Direct

Name: purQ [H]

Synonym: P9303_17251

Alternate gene names: 124023427

Gene position: 1509314-1509967 (Clockwise)

Preceding gene: 124023426

Following gene: 124023428

Centisome position: 56.26

GC content: 52.6

Gene sequence:

>654_bases
ATGAGTATTGGTGTTGTTGTCTTCCCTGGCTCAAATTGTGATCGCGATGTGCGCTGGGCAGCGCAAGGATGCTTGAACAT
CCCAACGCGCTTTCTCTGGCATGAGACCCGTGATTTAAATGGTCTTGATGCTGTTGTGCTTCCAGGCGGGTTTAGTTATG
GCGACTACCTCCGTTGTGGTGCAATTGCCCGCTTTGCGCCGGTGCTTGAATCGCTGGTGGAATTTGTTGCACGTGGCGGC
AGAGTGCTCGGCATCTGCAATGGCTTTCAGGTTCTGACTGAACTAGGTCTGCTCCCTGGAGCTCTAACCCGCAATCGAAG
CCTTCATTTCATCTGTGAGGATGCTTTGCTCACTGTGGAAAGCAATCGCACGCCTTGGCTAATGGGTCATCAACGCAAGG
ATGCTCTCACCCTGCCCATTGCCCATGGTGAGGGTCGATATCAGTGCAGTGACGAAACCCTTTGCCAGCTACAAGACGAT
GACGCTATCGCCTTGCGCTATGTCAATAATCCCAATGGTTCAGTGGCTGATATCGCTGGAATTACAAACAAGACTGGCAA
TGTGCTTGGCTTGATGCCCCATCCTGAACGGGCTTGTGATCCTGTGATTGGTGGCGTGGATGGCAGAGGATTGTTGCAGT
CACTGCTCGGCTGA

Upstream 100 bases:

>100_bases
CAGCTGGAACTGCTCAGTGATCGCCTGTTTGCCAATCCCGTGATTGAAGATTGGAGCCTTGAGCTTCAGCCGGTTCCTAC
AACCACCGCTTAATTCAGCC

Downstream 100 bases:

>100_bases
TTCACGATGCGACGGCGTTCGCTGCTGATGGGGGTTCCGGCTGCCTTAGCAGCAACCTTGACTTGGCCAAAGCTGGGGCA
AACGTTGACCCCAGCCTTTA

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MSIGVVVFPGSNCDRDVRWAAQGCLNIPTRFLWHETRDLNGLDAVVLPGGFSYGDYLRCGAIARFAPVLESLVEFVARGG
RVLGICNGFQVLTELGLLPGALTRNRSLHFICEDALLTVESNRTPWLMGHQRKDALTLPIAHGEGRYQCSDETLCQLQDD
DAIALRYVNNPNGSVADIAGITNKTGNVLGLMPHPERACDPVIGGVDGRGLLQSLLG

Sequences:

>Translated_217_residues
MSIGVVVFPGSNCDRDVRWAAQGCLNIPTRFLWHETRDLNGLDAVVLPGGFSYGDYLRCGAIARFAPVLESLVEFVARGG
RVLGICNGFQVLTELGLLPGALTRNRSLHFICEDALLTVESNRTPWLMGHQRKDALTLPIAHGEGRYQCSDETLCQLQDD
DAIALRYVNNPNGSVADIAGITNKTGNVLGLMPHPERACDPVIGGVDGRGLLQSLLG
>Mature_216_residues
SIGVVVFPGSNCDRDVRWAAQGCLNIPTRFLWHETRDLNGLDAVVLPGGFSYGDYLRCGAIARFAPVLESLVEFVARGGR
VLGICNGFQVLTELGLLPGALTRNRSLHFICEDALLTVESNRTPWLMGHQRKDALTLPIAHGEGRYQCSDETLCQLQDDD
AIALRYVNNPNGSVADIAGITNKTGNVLGLMPHPERACDPVIGGVDGRGLLQSLLG

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=183, Percent_Identity=33.879781420765, Blast_Score=78, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6321498, Length=182, Percent_Identity=31.3186813186813, Blast_Score=73, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24582111, Length=197, Percent_Identity=35.0253807106599, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24582109, Length=197, Percent_Identity=35.0253807106599, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17137292, Length=197, Percent_Identity=35.0253807106599, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 23427; Mature: 23296

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIGVVVFPGSNCDRDVRWAAQGCLNIPTRFLWHETRDLNGLDAVVLPGGFSYGDYLRCG
CCEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHH
AIARFAPVLESLVEFVARGGRVLGICNGFQVLTELGLLPGALTRNRSLHFICEDALLTVE
HHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCCCCCCCEEEEEECEEEEEE
SNRTPWLMGHQRKDALTLPIAHGEGRYQCSDETLCQLQDDDAIALRYVNNPNGSVADIAG
CCCCCEEECCCCCCEEEEEEECCCCCEEECCCCEEEECCCCEEEEEEEECCCCCEEEECC
ITNKTGNVLGLMPHPERACDPVIGGVDGRGLLQSLLG
CCCCCCCEEEECCCCHHHCCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
SIGVVVFPGSNCDRDVRWAAQGCLNIPTRFLWHETRDLNGLDAVVLPGGFSYGDYLRCG
CEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHH
AIARFAPVLESLVEFVARGGRVLGICNGFQVLTELGLLPGALTRNRSLHFICEDALLTVE
HHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCCCCCCCEEEEEECEEEEEE
SNRTPWLMGHQRKDALTLPIAHGEGRYQCSDETLCQLQDDDAIALRYVNNPNGSVADIAG
CCCCCEEECCCCCCEEEEEEECCCCCEEECCCCEEEECCCCEEEEEEEECCCCCEEEECC
ITNKTGNVLGLMPHPERACDPVIGGVDGRGLLQSLLG
CCCCCCCEEEECCCCHHHCCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]