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The map label for this gene is typA [H]

Identifier: 124023378

GI number: 124023378

Start: 1465224

End: 1467026

Strand: Direct

Name: typA [H]

Synonym: P9303_16761

Alternate gene names: 124023378

Gene position: 1465224-1467026 (Clockwise)

Preceding gene: 124023377

Following gene: 124023379

Centisome position: 54.62

GC content: 50.8

Gene sequence:

>1803_bases
ATGAGTGCCCAGGCCAAGGCGATCCGCAACATTGCAATTATCGCTCACGTGGATCACGGCAAAACAACCTTGGTTGATGC
CCTGTTGACTCAGTCCGGGATCTTCCGAGACAACGAGGCTGTGCCCACATGTGTCATGGACTCCAATGATTTGGAAAGGG
AACGGGGCATTACGATCCTTTCAAAGAACACGGCCGTTACCTACGACGAGACGCGGATCAACATTGTTGATACCCCTGGT
CATGCCGATTTTGGCGGTGAGGTTGAGCGGGTGCTCGGCATGGTTGATGGCTGTTTGCTGATCGTTGACGCCAACGAGGG
GCCTATGCCACAGACGCGTTTCGTGCTCAAGAAGGCGCTTGAGCAGGGATTGCGGCCGATTGTGTTCGTAAACAAGATTG
ATCGTGCGCGGGTGGATCCTGAAACCGCTGTCAACAAGGTGCTCGATCTGTTTATTGAACTCGGTGCAGATGATGACCAA
TGTGATTTCCCGTACTTATTCGGCAGTGGAATGGGAGGTTTTGCCAAGCCGGATATGGCAACTGAAAGTCAAACAATGAA
GCCACTATTTGATGCCATCCTGCGTCATGTTCCACCACCTGTTGGAGATGAGAACAAGCCTCTTCAGCTACAGATCACTA
CTCTCGATTATTCAGACTTCCTGGGCAGGATTGTGATTGGTCGGGTCCATAACGGGGTTATCCGTAATGGTCAGAGTGCT
TCGTTGATTAAGGATGATGGCAGCATTAAACGTGGCCGGATTAGCAAACTACTCGGTTTCGAAGGGTTGCAACGGATTGA
GATACAAGAAGCTGGAGCGGGAGATCTCGTTGCTTTGGCCGGTTTCGATCAAGTCAATATTGGCGAGACCATTGCCTGTC
CAGATGAACCAAAAGCTTTACCTCTAATCAAGGTGGATGAACCCACTTTGCAGATGACATTTGTCGTCAATGATTCACCC
TTTGCTGGCAAAGAAGGCAAATTCGTCACTAGCCGGCAGCTGCGAGATCGTTTACGCAAGGAATTACTCACCAATGTTGC
CTTACGCGTTGAGGACACTGATTCTCCTGATCGTTTTGCGGTTAGCGGGCGTGGTGAACTACACCTGGGCATCCTGATTG
AAACCATGCGCCGCGAGGGATTTGAGTTTCAGGTAACCCAGCCTCAGGTGATCTTCCGAACGATTGACGGCACTCCTTGC
GAGCCCGTTGAAACCTTGGTGATGGATGTACCAGAGGCAGCCGTTGGCGCCTGCATTGAGAAGTTGGGTGTGCGTCGGGG
TGAAATGCAGAACATGGAAACCGGTAACGACGGTCGCACCCAGCTTGAATTTGTTGTTCCTTCTCGGGGGTTGATCGGTT
TACGTGGTGAGTTTGTACGTGCTACCAGGGGTGAGGGAATTATGAGCCACTCTTTTTTTGAATATCGCCCAATGTTGGGA
GAGTTTGATGCTCGTCGGAATGGTGTTCTGATTGCTTTTGAACAGGGCACTGCGACCTTCTACGCACTCAAGAATGCTGA
GGGTCGTGGTCAGTTCTTCATCTCTCCGGGTGTCAAGGTTTATAAGGGGATGATCGTTGGCGAAAACAATCGACCTCAGG
ATATGGAGTTAAACGTTTGCAAGGCCAAACAACTCACAAATATCCGCTCTGCTGGTGCAGAAGAGCTCGATACCTTGCAG
ACACCTGTTCAGATGACCCTTGAACGTGCTCTTGAGTACATCGGTCCAGATGAAATGCTTGAGGTCACCCCAGAGTCCAT
TCGCTTGCGCAAGTTGCCTGCCAAGAAGATGGCCAAACGCTGA

Upstream 100 bases:

>100_bases
AGCGAAAGGGGCCTAGAAGTTAAGTTGAATCTCAAATTGAGATAGCCTTCCGCCACTACGCCTGTGTGCGTTTCCTTTTC
CTTTTGAAAGTCTCTGACCC

Downstream 100 bases:

>100_bases
AGCTCTTGATGGAGAGATTCCAGCCTACTGATCTGATCAATGATCCACGTTTTCAACTAGCCGTGGAGCTTTTTAATAAG
GCCGATTGGTACCCCGCTCA

Product: tyrosine binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 600; Mature: 599

Protein sequence:

>600_residues
MSAQAKAIRNIAIIAHVDHGKTTLVDALLTQSGIFRDNEAVPTCVMDSNDLERERGITILSKNTAVTYDETRINIVDTPG
HADFGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKALEQGLRPIVFVNKIDRARVDPETAVNKVLDLFIELGADDDQ
CDFPYLFGSGMGGFAKPDMATESQTMKPLFDAILRHVPPPVGDENKPLQLQITTLDYSDFLGRIVIGRVHNGVIRNGQSA
SLIKDDGSIKRGRISKLLGFEGLQRIEIQEAGAGDLVALAGFDQVNIGETIACPDEPKALPLIKVDEPTLQMTFVVNDSP
FAGKEGKFVTSRQLRDRLRKELLTNVALRVEDTDSPDRFAVSGRGELHLGILIETMRREGFEFQVTQPQVIFRTIDGTPC
EPVETLVMDVPEAAVGACIEKLGVRRGEMQNMETGNDGRTQLEFVVPSRGLIGLRGEFVRATRGEGIMSHSFFEYRPMLG
EFDARRNGVLIAFEQGTATFYALKNAEGRGQFFISPGVKVYKGMIVGENNRPQDMELNVCKAKQLTNIRSAGAEELDTLQ
TPVQMTLERALEYIGPDEMLEVTPESIRLRKLPAKKMAKR

Sequences:

>Translated_600_residues
MSAQAKAIRNIAIIAHVDHGKTTLVDALLTQSGIFRDNEAVPTCVMDSNDLERERGITILSKNTAVTYDETRINIVDTPG
HADFGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKALEQGLRPIVFVNKIDRARVDPETAVNKVLDLFIELGADDDQ
CDFPYLFGSGMGGFAKPDMATESQTMKPLFDAILRHVPPPVGDENKPLQLQITTLDYSDFLGRIVIGRVHNGVIRNGQSA
SLIKDDGSIKRGRISKLLGFEGLQRIEIQEAGAGDLVALAGFDQVNIGETIACPDEPKALPLIKVDEPTLQMTFVVNDSP
FAGKEGKFVTSRQLRDRLRKELLTNVALRVEDTDSPDRFAVSGRGELHLGILIETMRREGFEFQVTQPQVIFRTIDGTPC
EPVETLVMDVPEAAVGACIEKLGVRRGEMQNMETGNDGRTQLEFVVPSRGLIGLRGEFVRATRGEGIMSHSFFEYRPMLG
EFDARRNGVLIAFEQGTATFYALKNAEGRGQFFISPGVKVYKGMIVGENNRPQDMELNVCKAKQLTNIRSAGAEELDTLQ
TPVQMTLERALEYIGPDEMLEVTPESIRLRKLPAKKMAKR
>Mature_599_residues
SAQAKAIRNIAIIAHVDHGKTTLVDALLTQSGIFRDNEAVPTCVMDSNDLERERGITILSKNTAVTYDETRINIVDTPGH
ADFGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKALEQGLRPIVFVNKIDRARVDPETAVNKVLDLFIELGADDDQC
DFPYLFGSGMGGFAKPDMATESQTMKPLFDAILRHVPPPVGDENKPLQLQITTLDYSDFLGRIVIGRVHNGVIRNGQSAS
LIKDDGSIKRGRISKLLGFEGLQRIEIQEAGAGDLVALAGFDQVNIGETIACPDEPKALPLIKVDEPTLQMTFVVNDSPF
AGKEGKFVTSRQLRDRLRKELLTNVALRVEDTDSPDRFAVSGRGELHLGILIETMRREGFEFQVTQPQVIFRTIDGTPCE
PVETLVMDVPEAAVGACIEKLGVRRGEMQNMETGNDGRTQLEFVVPSRGLIGLRGEFVRATRGEGIMSHSFFEYRPMLGE
FDARRNGVLIAFEQGTATFYALKNAEGRGQFFISPGVKVYKGMIVGENNRPQDMELNVCKAKQLTNIRSAGAEELDTLQT
PVQMTLERALEYIGPDEMLEVTPESIRLRKLPAKKMAKR

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI94966754, Length=157, Percent_Identity=41.4012738853503, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI157426893, Length=234, Percent_Identity=35.042735042735, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI34147630, Length=274, Percent_Identity=29.9270072992701, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI4503483, Length=145, Percent_Identity=38.6206896551724, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI18390331, Length=145, Percent_Identity=41.3793103448276, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI310132016, Length=110, Percent_Identity=44.5454545454545, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI310110807, Length=110, Percent_Identity=44.5454545454545, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI310123363, Length=110, Percent_Identity=44.5454545454545, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI25306283, Length=144, Percent_Identity=40.9722222222222, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI19923640, Length=144, Percent_Identity=40.9722222222222, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI25306287, Length=144, Percent_Identity=40.9722222222222, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI217272894, Length=138, Percent_Identity=37.6811594202899, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI217272892, Length=138, Percent_Identity=37.6811594202899, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI94966752, Length=153, Percent_Identity=30.0653594771242, Blast_Score=83, Evalue=7e-16,
Organism=Escherichia coli, GI48994988, Length=589, Percent_Identity=52.6315789473684, Blast_Score=624, Evalue=1e-180,
Organism=Escherichia coli, GI1788922, Length=545, Percent_Identity=27.5229357798165, Blast_Score=142, Evalue=9e-35,
Organism=Escherichia coli, GI1789738, Length=148, Percent_Identity=39.8648648648649, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1790412, Length=290, Percent_Identity=28.6206896551724, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1789737, Length=290, Percent_Identity=28.6206896551724, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790835, Length=145, Percent_Identity=31.7241379310345, Blast_Score=83, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17557151, Length=311, Percent_Identity=29.5819935691318, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17506493, Length=219, Percent_Identity=32.4200913242009, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71988811, Length=135, Percent_Identity=39.2592592592593, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71988819, Length=135, Percent_Identity=39.2592592592593, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17556745, Length=142, Percent_Identity=40.1408450704225, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17533571, Length=143, Percent_Identity=42.6573426573427, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17556456, Length=283, Percent_Identity=27.9151943462898, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17552882, Length=134, Percent_Identity=34.3283582089552, Blast_Score=86, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI25141371, Length=271, Percent_Identity=26.5682656826568, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323320, Length=518, Percent_Identity=26.8339768339768, Blast_Score=130, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6324761, Length=304, Percent_Identity=30.9210526315789, Blast_Score=113, Evalue=9e-26,
Organism=Saccharomyces cerevisiae, GI6324707, Length=204, Percent_Identity=35.2941176470588, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6320593, Length=204, Percent_Identity=35.2941176470588, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6323098, Length=156, Percent_Identity=38.4615384615385, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322359, Length=148, Percent_Identity=39.8648648648649, Blast_Score=97, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6324166, Length=143, Percent_Identity=38.4615384615385, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI78706572, Length=527, Percent_Identity=25.2371916508539, Blast_Score=119, Evalue=7e-27,
Organism=Drosophila melanogaster, GI28574573, Length=206, Percent_Identity=34.9514563106796, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24585711, Length=168, Percent_Identity=35.7142857142857, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24585713, Length=168, Percent_Identity=35.7142857142857, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24585709, Length=168, Percent_Identity=35.7142857142857, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI281363316, Length=297, Percent_Identity=29.2929292929293, Blast_Score=106, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17864358, Length=297, Percent_Identity=29.2929292929293, Blast_Score=106, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24582462, Length=145, Percent_Identity=40.6896551724138, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI221458488, Length=147, Percent_Identity=41.4965986394558, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357743, Length=190, Percent_Identity=34.2105263157895, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI19921738, Length=279, Percent_Identity=30.4659498207885, Blast_Score=86, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 66202; Mature: 66071

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQAKAIRNIAIIAHVDHGKTTLVDALLTQSGIFRDNEAVPTCVMDSNDLERERGITIL
CCCHHHHHCEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHCCEEEE
SKNTAVTYDETRINIVDTPGHADFGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKAL
ECCEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
EQGLRPIVFVNKIDRARVDPETAVNKVLDLFIELGADDDQCDFPYLFGSGMGGFAKPDMA
HHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCC
TESQTMKPLFDAILRHVPPPVGDENKPLQLQITTLDYSDFLGRIVIGRVHNGVIRNGQSA
CCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECHHHHHHHEEHHHHCCCHHCCCCCC
SLIKDDGSIKRGRISKLLGFEGLQRIEIQEAGAGDLVALAGFDQVNIGETIACPDEPKAL
EEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCCCEEECCCCCCCC
PLIKVDEPTLQMTFVVNDSPFAGKEGKFVTSRQLRDRLRKELLTNVALRVEDTDSPDRFA
EEEEECCCCEEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHEEEEEECCCCCCEEE
VSGRGELHLGILIETMRREGFEFQVTQPQVIFRTIDGTPCEPVETLVMDVPEAAVGACIE
ECCCCCEEEHHHHHHHHHCCCEEEECCCEEEEEECCCCCCCHHHHHHHCCCHHHHHHHHH
KLGVRRGEMQNMETGNDGRTQLEFVVPSRGLIGLRGEFVRATRGEGIMSHSFFEYRPMLG
HHCCCCCCCCCCCCCCCCCEEEEEEECCCCEEECCCCEEEECCCCCCHHCCHHHHCCCCC
EFDARRNGVLIAFEQGTATFYALKNAEGRGQFFISPGVKVYKGMIVGENNRPQDMELNVC
CCCCCCCCEEEEEECCCEEEEEEECCCCCCEEEECCCCEEEEEEEECCCCCCCCCEEEHH
KAKQLTNIRSAGAEELDTLQTPVQMTLERALEYIGPDEMLEVTPESIRLRKLPAKKMAKR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHEEECCCHHHHHCC
>Mature Secondary Structure 
SAQAKAIRNIAIIAHVDHGKTTLVDALLTQSGIFRDNEAVPTCVMDSNDLERERGITIL
CCHHHHHCEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHCCEEEE
SKNTAVTYDETRINIVDTPGHADFGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKAL
ECCEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
EQGLRPIVFVNKIDRARVDPETAVNKVLDLFIELGADDDQCDFPYLFGSGMGGFAKPDMA
HHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCC
TESQTMKPLFDAILRHVPPPVGDENKPLQLQITTLDYSDFLGRIVIGRVHNGVIRNGQSA
CCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECHHHHHHHEEHHHHCCCHHCCCCCC
SLIKDDGSIKRGRISKLLGFEGLQRIEIQEAGAGDLVALAGFDQVNIGETIACPDEPKAL
EEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCCCEEECCCCCCCC
PLIKVDEPTLQMTFVVNDSPFAGKEGKFVTSRQLRDRLRKELLTNVALRVEDTDSPDRFA
EEEEECCCCEEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHEEEEEECCCCCCEEE
VSGRGELHLGILIETMRREGFEFQVTQPQVIFRTIDGTPCEPVETLVMDVPEAAVGACIE
ECCCCCEEEHHHHHHHHHCCCEEEECCCEEEEEECCCCCCCHHHHHHHCCCHHHHHHHHH
KLGVRRGEMQNMETGNDGRTQLEFVVPSRGLIGLRGEFVRATRGEGIMSHSFFEYRPMLG
HHCCCCCCCCCCCCCCCCCEEEEEEECCCCEEECCCCEEEECCCCCCHHCCHHHHCCCCC
EFDARRNGVLIAFEQGTATFYALKNAEGRGQFFISPGVKVYKGMIVGENNRPQDMELNVC
CCCCCCCCEEEEEECCCEEEEEEECCCCCCEEEECCCCEEEEEEEECCCCCCCCCEEEHH
KAKQLTNIRSAGAEELDTLQTPVQMTLERALEYIGPDEMLEVTPESIRLRKLPAKKMAKR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHEEECCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]