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The map label for this gene is lspA [H]

Identifier: 124023355

GI number: 124023355

Start: 1443677

End: 1444174

Strand: Reverse

Name: lspA [H]

Synonym: P9303_16531

Alternate gene names: 124023355

Gene position: 1444174-1443677 (Counterclockwise)

Preceding gene: 124023356

Following gene: 124023354

Centisome position: 53.83

GC content: 50.2

Gene sequence:

>498_bases
ATGAATCAACCTCAAATACTGAAGCAACGTCAACTATCACGCCGGGCAATGCTGCTAATCAGCATCCTGCTGATGCTGAT
TGATCAGATCAGCAAAAGCTGGGCCCGTGAACAACTCAGTTCAGGCTTCGTATTCCCTTTTGTTCCTGGGCTATTGCAGT
TGCGTCTGATCAGCAATACAGGCGCAGCTTTTAATCTTTTCAATGGAGCAACATTCCTCTTAGGGCTGCTCAGCCTGGTT
GTGACCATTGGTTTGATGGTCTGGATATGGAGAGCAGGACAGATGCCGATATGGCAAGGCCTTGCCGTTTCCTTTCTGCT
CGGCGGAACCATCGGCAATGGCTTGGACCGATGGCGTCTAGGGCACGTCACCGACTTTCTGCAACTTGTACCGGTGGACT
TTCCGATTTTCAATGGAGCTGATGTGGCGATCAATTTGGCCGTGATCTGCTTCGGAATCGATGCCTTGACAAGACGCCAT
GGACAACAACACACCTAA

Upstream 100 bases:

>100_bases
TGCTATTTAGCTATACCTTTGGCCCCCTACCCGCTCAACTAGTCCTCTGTGCAGGCGTTGGCGTACTTGCTTTGCCATTG
CGAAATCTGCTGTTTGTTGA

Downstream 100 bases:

>100_bases
GCGATTTGCGATGACTGGAGTGATCATCCATCAGATCAGTCAAACCGATCGAAAAGCTTTTCTTTAAAGCGATAGTTGCC
GGTTTAGTGGAAACGAAAAG

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MNQPQILKQRQLSRRAMLLISILLMLIDQISKSWAREQLSSGFVFPFVPGLLQLRLISNTGAAFNLFNGATFLLGLLSLV
VTIGLMVWIWRAGQMPIWQGLAVSFLLGGTIGNGLDRWRLGHVTDFLQLVPVDFPIFNGADVAINLAVICFGIDALTRRH
GQQHT

Sequences:

>Translated_165_residues
MNQPQILKQRQLSRRAMLLISILLMLIDQISKSWAREQLSSGFVFPFVPGLLQLRLISNTGAAFNLFNGATFLLGLLSLV
VTIGLMVWIWRAGQMPIWQGLAVSFLLGGTIGNGLDRWRLGHVTDFLQLVPVDFPIFNGADVAINLAVICFGIDALTRRH
GQQHT
>Mature_165_residues
MNQPQILKQRQLSRRAMLLISILLMLIDQISKSWAREQLSSGFVFPFVPGLLQLRLISNTGAAFNLFNGATFLLGLLSLV
VTIGLMVWIWRAGQMPIWQGLAVSFLLGGTIGNGLDRWRLGHVTDFLQLVPVDFPIFNGADVAINLAVICFGIDALTRRH
GQQHT

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 18325; Mature: 18325

Theoretical pI: Translated: 11.65; Mature: 11.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQPQILKQRQLSRRAMLLISILLMLIDQISKSWAREQLSSGFVFPFVPGLLQLRLISNT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
GAAFNLFNGATFLLGLLSLVVTIGLMVWIWRAGQMPIWQGLAVSFLLGGTIGNGLDRWRL
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHCCCHHHHHH
GHVTDFLQLVPVDFPIFNGADVAINLAVICFGIDALTRRHGQQHT
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNQPQILKQRQLSRRAMLLISILLMLIDQISKSWAREQLSSGFVFPFVPGLLQLRLISNT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
GAAFNLFNGATFLLGLLSLVVTIGLMVWIWRAGQMPIWQGLAVSFLLGGTIGNGLDRWRL
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHCCCHHHHHH
GHVTDFLQLVPVDFPIFNGADVAINLAVICFGIDALTRRHGQQHT
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12917641 [H]